Click here to switch to the map view.

The map label for this gene is nuoE [H]

Identifier: 134299513

GI number: 134299513

Start: 1814446

End: 1814937

Strand: Reverse

Name: nuoE [H]

Synonym: Dred_1656

Alternate gene names: 134299513

Gene position: 1814937-1814446 (Counterclockwise)

Preceding gene: 134299532

Following gene: 134299512

Centisome position: 50.3

GC content: 41.87

Gene sequence:

>492_bases
ATGATGGAAAATAGAGATATAAAATTCCTAAATGTTCAAAAGATAATTGATTCACACGAGGGAAAGGTTTCTCATTTGAT
TGGAATATTACAAGAAGTGCAATCAGACTACGGTTATTTGCCGAAGGAAGTTTTAACCTACATAGCTACATCAATGGGAA
TCTCCCCAGCCACCGTACTGGGAGTAGCAACCTTCTATGCTCAGTTTTCTCTAATCCCAAAGGGCAAGTACGTTATCCGT
GTTTGTGATGGAACTGCATGTCACGTGCGTGGGTCAGAGCCCATTATGATGGCGTTACGAAAGGAACTTGGCATTAACAC
AGAAAAACCAACCACGGATGATTTAATGTTTACTTTAGAAACAGTCTCCTGTTTAGGAGCTTGCGGACTAGCTCCAGTTG
TGGTTGCCGATGAGGAAGTTCATGGTCAAATGACCCCGGATGGGATCTTAGAAATAGTAAGAAAATTGGCACCTGCTGCC
AGTGAAAATTAG

Upstream 100 bases:

>100_bases
TCATTTGGCTCTATTTATTTTTGAAAAGAGGTGGTTTTAAAAATTAACATCATATCAGTTATAGGCAGATCACATGGTTT
TTAACACCAAAGGGGGGTTT

Downstream 100 bases:

>100_bases
GGGGGACTATAGATGCTAATAAAAAGTCATGATGATCTAAAACAACTTAGACAGAAGGTAAAGGCTGCCCTTGATCAAGA
AAAGATGCGCATCTTAGTCT

Product: NADH dehydrogenase (ubiquinone), 24 kDa subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MMENRDIKFLNVQKIIDSHEGKVSHLIGILQEVQSDYGYLPKEVLTYIATSMGISPATVLGVATFYAQFSLIPKGKYVIR
VCDGTACHVRGSEPIMMALRKELGINTEKPTTDDLMFTLETVSCLGACGLAPVVVADEEVHGQMTPDGILEIVRKLAPAA
SEN

Sequences:

>Translated_163_residues
MMENRDIKFLNVQKIIDSHEGKVSHLIGILQEVQSDYGYLPKEVLTYIATSMGISPATVLGVATFYAQFSLIPKGKYVIR
VCDGTACHVRGSEPIMMALRKELGINTEKPTTDDLMFTLETVSCLGACGLAPVVVADEEVHGQMTPDGILEIVRKLAPAA
SEN
>Mature_163_residues
MMENRDIKFLNVQKIIDSHEGKVSHLIGILQEVQSDYGYLPKEVLTYIATSMGISPATVLGVATFYAQFSLIPKGKYVIR
VCDGTACHVRGSEPIMMALRKELGINTEKPTTDDLMFTLETVSCLGACGLAPVVVADEEVHGQMTPDGILEIVRKLAPAA
SEN

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=151, Percent_Identity=35.7615894039735, Blast_Score=93, Evalue=1e-19,
Organism=Escherichia coli, GI1788621, Length=129, Percent_Identity=40.3100775193798, Blast_Score=99, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17561328, Length=162, Percent_Identity=35.1851851851852, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI18859877, Length=135, Percent_Identity=37.037037037037, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI21355353, Length=143, Percent_Identity=32.1678321678322, Blast_Score=85, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 17727; Mature: 17727

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMENRDIKFLNVQKIIDSHEGKVSHLIGILQEVQSDYGYLPKEVLTYIATSMGISPATVL
CCCCCCCCEEHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHH
GVATFYAQFSLIPKGKYVIRVCDGTACHVRGSEPIMMALRKELGINTEKPTTDDLMFTLE
HHHHHHHHHHCCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHH
TVSCLGACGLAPVVVADEEVHGQMTPDGILEIVRKLAPAASEN
HHHHHHHCCCCCEEEECHHHCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMENRDIKFLNVQKIIDSHEGKVSHLIGILQEVQSDYGYLPKEVLTYIATSMGISPATVL
CCCCCCCCEEHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHH
GVATFYAQFSLIPKGKYVIRVCDGTACHVRGSEPIMMALRKELGINTEKPTTDDLMFTLE
HHHHHHHHHHCCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHH
TVSCLGACGLAPVVVADEEVHGQMTPDGILEIVRKLAPAASEN
HHHHHHHCCCCCEEEECHHHCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12522265 [H]