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The map label for this gene is yqiR [H]

Identifier: 134299353

GI number: 134299353

Start: 1617261

End: 1618673

Strand: Reverse

Name: yqiR [H]

Synonym: Dred_1494

Alternate gene names: 134299353

Gene position: 1618673-1617261 (Counterclockwise)

Preceding gene: 134299355

Following gene: 134299352

Centisome position: 44.86

GC content: 37.72

Gene sequence:

>1413_bases
TTGGAAATTCATAAGTCAAGAGACCACCAAATAATAGAACAAGAATTGAACGAAAATCAAGTCTTAGCCTCTATGTGGGA
TGTACTTATCGAAAATCCTTATGAAGGTATGATTGTTGTAAACGCACAGGGGTATATTATCTTTATTAATAATACCTATC
TAAATATTTTAGGTCTCAAAAAAAGTGATGCTATAGGAAAACATGTTTGGGATGTTACCAGCCATTCTCAATTACCCCAG
GTGATTGAGACAGGCCGCCCCATTTTATATGATTTCTGGGAAGTCAATGGTCGTAAACTAATTGTTGTACGTATTCCCAT
TATTAACAACGAAGGCAACGTTATTGGAGCCATCGGGAAATCTCTCTTTACCGATATACCTTCAGGAAAACTGCTATTTA
CTAAACTGCAGGTATTGGAAAAGGAGTTAGCTTTTTACAAAGAAGAAATACGCAAGGTTTATAAGGCTAAATACTCTTGT
AAAAATCTAATTGGAGAAAGCGAGTCAGTTAAGGAAATAAAAAAACTTGCCCGCAAGGTGGCCTCTTCTAACTCCACCAT
TCTGATTACCGGCGAAAGCGGTACAGGCAAGGAACTACTTGCCCAGGCCATACATAACGCCGGTTGCCGAAACCAAAGGC
CCTTCGTTCGGGTAAATTGTGCTGCTGTACCAGAAAATCTACTTGAGACAGAACTTTTTGGCTACGATGACGGAGCCTTC
ACCGGGGCCAAAAAAGGTGGTAAACCTGGTAAATTTGAATTAGCCCAAGGAGGTACCATTTTCTTGGATGAAATTGGGGA
AATACCTCTCACTATGCAGTCAAAACTTTTGGCCGTTCTACAGGAAAGGGAATTGGAGCGTGTAGGGGGAATTAAGACTG
TTCCTTTAGATGTACGGGTTATTTCAGCCACCAACCGAAACCTTGAGGATATGGTTAAAAATGGTACTTTTCGGGAGGAT
CTTTATTATCGTTTAAATGTAATAAACTTTCGATTACCTTCACTGCGAGAACGTTCAGAGGATATTCCTCTGTTAGTTAA
TTATTTGACTCATAAACTAAATAAAAAGTTAAATTGTCATGTGGAAGGGTACACAGAGCAAGCTATGCAACTGCTAACAA
AATATCATTGGCCTGGAAATGTAAGACAGTTGGAAAATGCTTTAGAAAGAATGTTTAGTTTTACAGATGATAAGATCTTA
TCCACAGAGCATATGCCTTTTCTCAAAAAAATTGTTAATGTTAATTCTAGTGAAGTTAATACAAAATCTTTAGCCGAGAC
CATTGCTGAAACCGAGAAGAAAATGATTTTGGATGCCTTGCAAAAGGTTGATGGCAATCGAAATAAGGCTGCGAAGCTTC
TGGATATACATCTTTCGGTTTTATACAGAAAAATAAAAAAATATGATATTTAA

Upstream 100 bases:

>100_bases
TCCCTTTTATTGTTAAAATTCAACAAAAAGTTTTGCAGGATATTTTTTATAATTGAAGAAATTTTTAAATAATTTAATAA
ATTCTTGGGAGGGGGTCGCT

Downstream 100 bases:

>100_bases
TACTAGTCCTCACCTTTTAAGGGTGAGGCTTTTTTAGCATATCAGAAAGTATAAAACTTTCCGATATGCATAAGGGCAAA
CTAAGGCTCCGCCGACGTCT

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MEIHKSRDHQIIEQELNENQVLASMWDVLIENPYEGMIVVNAQGYIIFINNTYLNILGLKKSDAIGKHVWDVTSHSQLPQ
VIETGRPILYDFWEVNGRKLIVVRIPIINNEGNVIGAIGKSLFTDIPSGKLLFTKLQVLEKELAFYKEEIRKVYKAKYSC
KNLIGESESVKEIKKLARKVASSNSTILITGESGTGKELLAQAIHNAGCRNQRPFVRVNCAAVPENLLETELFGYDDGAF
TGAKKGGKPGKFELAQGGTIFLDEIGEIPLTMQSKLLAVLQERELERVGGIKTVPLDVRVISATNRNLEDMVKNGTFRED
LYYRLNVINFRLPSLRERSEDIPLLVNYLTHKLNKKLNCHVEGYTEQAMQLLTKYHWPGNVRQLENALERMFSFTDDKIL
STEHMPFLKKIVNVNSSEVNTKSLAETIAETEKKMILDALQKVDGNRNKAAKLLDIHLSVLYRKIKKYDI

Sequences:

>Translated_470_residues
MEIHKSRDHQIIEQELNENQVLASMWDVLIENPYEGMIVVNAQGYIIFINNTYLNILGLKKSDAIGKHVWDVTSHSQLPQ
VIETGRPILYDFWEVNGRKLIVVRIPIINNEGNVIGAIGKSLFTDIPSGKLLFTKLQVLEKELAFYKEEIRKVYKAKYSC
KNLIGESESVKEIKKLARKVASSNSTILITGESGTGKELLAQAIHNAGCRNQRPFVRVNCAAVPENLLETELFGYDDGAF
TGAKKGGKPGKFELAQGGTIFLDEIGEIPLTMQSKLLAVLQERELERVGGIKTVPLDVRVISATNRNLEDMVKNGTFRED
LYYRLNVINFRLPSLRERSEDIPLLVNYLTHKLNKKLNCHVEGYTEQAMQLLTKYHWPGNVRQLENALERMFSFTDDKIL
STEHMPFLKKIVNVNSSEVNTKSLAETIAETEKKMILDALQKVDGNRNKAAKLLDIHLSVLYRKIKKYDI
>Mature_470_residues
MEIHKSRDHQIIEQELNENQVLASMWDVLIENPYEGMIVVNAQGYIIFINNTYLNILGLKKSDAIGKHVWDVTSHSQLPQ
VIETGRPILYDFWEVNGRKLIVVRIPIINNEGNVIGAIGKSLFTDIPSGKLLFTKLQVLEKELAFYKEEIRKVYKAKYSC
KNLIGESESVKEIKKLARKVASSNSTILITGESGTGKELLAQAIHNAGCRNQRPFVRVNCAAVPENLLETELFGYDDGAF
TGAKKGGKPGKFELAQGGTIFLDEIGEIPLTMQSKLLAVLQERELERVGGIKTVPLDVRVISATNRNLEDMVKNGTFRED
LYYRLNVINFRLPSLRERSEDIPLLVNYLTHKLNKKLNCHVEGYTEQAMQLLTKYHWPGNVRQLENALERMFSFTDDKIL
STEHMPFLKKIVNVNSSEVNTKSLAETIAETEKKMILDALQKVDGNRNKAAKLLDIHLSVLYRKIKKYDI

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=337, Percent_Identity=45.1038575667656, Blast_Score=294, Evalue=9e-81,
Organism=Escherichia coli, GI1789233, Length=463, Percent_Identity=36.0691144708423, Blast_Score=275, Evalue=5e-75,
Organism=Escherichia coli, GI1790437, Length=336, Percent_Identity=42.8571428571429, Blast_Score=269, Evalue=2e-73,
Organism=Escherichia coli, GI87082117, Length=234, Percent_Identity=51.7094017094017, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI1786524, Length=335, Percent_Identity=41.4925373134328, Blast_Score=254, Evalue=8e-69,
Organism=Escherichia coli, GI1789087, Length=314, Percent_Identity=43.312101910828, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI1788905, Length=294, Percent_Identity=42.1768707482993, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1790299, Length=377, Percent_Identity=35.0132625994695, Blast_Score=241, Evalue=8e-65,
Organism=Escherichia coli, GI87082152, Length=315, Percent_Identity=40, Blast_Score=223, Evalue=3e-59,
Organism=Escherichia coli, GI87081872, Length=320, Percent_Identity=39.6875, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1787583, Length=310, Percent_Identity=35.8064516129032, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI87081858, Length=452, Percent_Identity=26.7699115044248, Blast_Score=162, Evalue=6e-41,
Organism=Escherichia coli, GI1789828, Length=234, Percent_Identity=35.8974358974359, Blast_Score=132, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR002197
- InterPro:   IPR016040
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 53314; Mature: 53314

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIHKSRDHQIIEQELNENQVLASMWDVLIENPYEGMIVVNAQGYIIFINNTYLNILGLK
CCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCEEEEEEECCEEEEEECC
KSDAIGKHVWDVTSHSQLPQVIETGRPILYDFWEVNGRKLIVVRIPIINNEGNVIGAIGK
CCCCHHHHHHCCCCCCCCHHHHHCCCCEEEEEEECCCCEEEEEEEEEECCCCCEEEHHHH
SLFTDIPSGKLLFTKLQVLEKELAFYKEEIRKVYKAKYSCKNLIGESESVKEIKKLARKV
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ASSNSTILITGESGTGKELLAQAIHNAGCRNQRPFVRVNCAAVPENLLETELFGYDDGAF
HCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEHHHCCHHHHHHHHCCCCCCCC
TGAKKGGKPGKFELAQGGTIFLDEIGEIPLTMQSKLLAVLQERELERVGGIKTVPLDVRV
CCCCCCCCCCCEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECEEEEE
ISATNRNLEDMVKNGTFREDLYYRLNVINFRLPSLRERSEDIPLLVNYLTHKLNKKLNCH
EECCCCCHHHHHHCCCCHHHHHEEEEEEEEECCCHHHCCCCCHHHHHHHHHHHCCCEEEE
VEGYTEQAMQLLTKYHWPGNVRQLENALERMFSFTDDKILSTEHMPFLKKIVNVNSSEVN
ECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCC
TKSLAETIAETEKKMILDALQKVDGNRNKAAKLLDIHLSVLYRKIKKYDI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEIHKSRDHQIIEQELNENQVLASMWDVLIENPYEGMIVVNAQGYIIFINNTYLNILGLK
CCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCEEEEEEECCEEEEEECC
KSDAIGKHVWDVTSHSQLPQVIETGRPILYDFWEVNGRKLIVVRIPIINNEGNVIGAIGK
CCCCHHHHHHCCCCCCCCHHHHHCCCCEEEEEEECCCCEEEEEEEEEECCCCCEEEHHHH
SLFTDIPSGKLLFTKLQVLEKELAFYKEEIRKVYKAKYSCKNLIGESESVKEIKKLARKV
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ASSNSTILITGESGTGKELLAQAIHNAGCRNQRPFVRVNCAAVPENLLETELFGYDDGAF
HCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEHHHCCHHHHHHHHCCCCCCCC
TGAKKGGKPGKFELAQGGTIFLDEIGEIPLTMQSKLLAVLQERELERVGGIKTVPLDVRV
CCCCCCCCCCCEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECEEEEE
ISATNRNLEDMVKNGTFREDLYYRLNVINFRLPSLRERSEDIPLLVNYLTHKLNKKLNCH
EECCCCCHHHHHHCCCCHHHHHEEEEEEEEECCCHHHCCCCCHHHHHHHHHHHCCCEEEE
VEGYTEQAMQLLTKYHWPGNVRQLENALERMFSFTDDKILSTEHMPFLKKIVNVNSSEVN
ECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCC
TKSLAETIAETEKKMILDALQKVDGNRNKAAKLLDIHLSVLYRKIKKYDI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]