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The map label for this gene is hupA

Identifier: 13357842

GI number: 13357842

Start: 317402

End: 317794

Strand: Direct

Name: hupA

Synonym: UU282

Alternate gene names: 13357842

Gene position: 317402-317794 (Clockwise)

Preceding gene: 13357841

Following gene: 13357843

Centisome position: 42.22

GC content: 27.74

Gene sequence:

>393_bases
ATGAATGCAAAAATTAAAGCCAAAACACGTTCACAAATGATAGATGAATTATCAAAAATGTTAAATATTGAAAAAAAACA
AACAAAAGCATTTATGGATACTTACGAAGCTTTTTTAATTCTTGAATTATCACGAGCTAAAGAAGTTCGTTTAGGAAATA
TTGGAAAATTCAAGGTTAGTGTACGTGCAGAACGTAAGGGAATTAACCCTAAAACGGGTGAAACTGTAATTATTCCCGAG
AAAACAATTCCTAAATTTACTTTTACTAAAGGAATTAAAGAAATTATTAATGCTGGTATTTCAATTGATAATGAAAGAGT
ATCGATTGATGATAATGATTTTGATGATGACGATGAATTTGTAGAAGAGTACATTGTATCAGAAAATAATTAA

Upstream 100 bases:

>100_bases
TTTAATTTTAAAAATAAATAAATTATTATTTAATGGTTAATTTTTATAAAATTAATTATAAAAATAACATTTACTAAATT
CAAAGAAAGAACAAAGCCTT

Downstream 100 bases:

>100_bases
TTAATAATATGAAAACACGAGTTTTAATAACTCGTGTTTTGTTATTATTTAAATAAGTATAATAAATGATTATAACTTAT
TTTTAATAATGGAGTAATTA

Product: DNA-binding protein HU-alpha (HU-2)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MNAKIKAKTRSQMIDELSKMLNIEKKQTKAFMDTYEAFLILELSRAKEVRLGNIGKFKVSVRAERKGINPKTGETVIIPE
KTIPKFTFTKGIKEIINAGISIDNERVSIDDNDFDDDDEFVEEYIVSENN

Sequences:

>Translated_130_residues
MNAKIKAKTRSQMIDELSKMLNIEKKQTKAFMDTYEAFLILELSRAKEVRLGNIGKFKVSVRAERKGINPKTGETVIIPE
KTIPKFTFTKGIKEIINAGISIDNERVSIDDNDFDDDDEFVEEYIVSENN
>Mature_130_residues
MNAKIKAKTRSQMIDELSKMLNIEKKQTKAFMDTYEAFLILELSRAKEVRLGNIGKFKVSVRAERKGINPKTGETVIIPE
KTIPKFTFTKGIKEIINAGISIDNERVSIDDNDFDDDDEFVEEYIVSENN

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family

Homologues:

None

Paralogues:

None

Copy number: 1380 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DBH_UREPA (Q9PQK9)

Other databases:

- EMBL:   AF222894
- RefSeq:   NP_078116.1
- ProteinModelPortal:   Q9PQK9
- SMR:   Q9PQK9
- GeneID:   875782
- GenomeReviews:   AF222894_GR
- KEGG:   uur:UU282
- HOGENOM:   HBG734405
- OMA:   MNSITYE
- ProtClustDB:   CLSK2298861
- BioCyc:   UURE95667:UU282-MONOMER
- InterPro:   IPR000119
- InterPro:   IPR010992
- Gene3D:   G3DSA:4.10.520.10
- PRINTS:   PR01727
- SMART:   SM00411

Pfam domain/function: PF00216 Bac_DNA_binding; SSF47729 IHF_like_DNA_bnd

EC number: NA

Molecular weight: Translated: 14862; Mature: 14862

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAKIKAKTRSQMIDELSKMLNIEKKQTKAFMDTYEAFLILELSRAKEVRLGNIGKFKVS
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEECCCCCEECCCCCCEEEEE
VRAERKGINPKTGETVIIPEKTIPKFTFTKGIKEIINAGISIDNERVSIDDNDFDDDDEF
EEECCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHH
VEEYIVSENN
HHHHHHCCCC
>Mature Secondary Structure
MNAKIKAKTRSQMIDELSKMLNIEKKQTKAFMDTYEAFLILELSRAKEVRLGNIGKFKVS
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEECCCCCEECCCCCCEEEEE
VRAERKGINPKTGETVIIPEKTIPKFTFTKGIKEIINAGISIDNERVSIDDNDFDDDDEF
EEECCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHH
VEEYIVSENN
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11048724