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The map label for this gene is deoD

Identifier: 13357841

GI number: 13357841

Start: 316587

End: 317306

Strand: Direct

Name: deoD

Synonym: UU281

Alternate gene names: 13357841

Gene position: 316587-317306 (Clockwise)

Preceding gene: 13357840

Following gene: 13357842

Centisome position: 42.12

GC content: 30.69

Gene sequence:

>720_bases
ATGACTGCACATAATCAAGCTAAATTAGGAGAAATAGCTAAAGTAGTACTAATGCCAGGGGACCCAATGCGCGCTAAATG
AATTGCTGAAACTTTTTTAGAAAATGCAATTTTAGTTAATGAAGTTCGTGGCATGCTATGCTATACAGGAACATATAAAG
GCAAAAAAATATCAATTATGGGCCATGGTATGGGAATTCCTTCGATCGGAATTTATTCATATGAATTATATAAATTTTAT
GAAGTTGAAACAATTATTCGTGTTGGTTCAACTGGTTCATATAAAAAAGATTTGAATGTTAATGATGTGGTTTTAGTTGA
AAAATCATATAGTGATTCTACATTCGCATCACTGATTGGTGCACAAGTTGGCGATGATAAGGTTTTATTACCATCAAGAG
AAGTTAATAATTTAATTAAAAATACTGCGAAGGAATTAAATTTAGAATTATCATTAGCAACTTGTCATGCTTCTGATGTG
TTTTATAATAATGATTTTCAAACATTAGATGAAATTATTCATCGAACTAAATCCGATTGTGTTGATATGGAATCATTTGG
TTTATTCGCAAATGCACAAATTTTAAATAAAAATGCAGCAACTTTACTAACAGTTAGTGATTCATTGATTACAGGTGATG
CACTATCACCCGCAGAGCGTGCTAATACTTTTAAAAAAATGGTAACATTAGCCTTAGAAAGCGCAATTAAATTACTTTAA

Upstream 100 bases:

>100_bases
GAATTTGAAAAAGTAAAATTTAAATAATTTTTATATCAAATAAAAACCTTTTAATATAAAATTAAATATCGTAATAAATT
TATTTTTAGGAGAATAAAAT

Downstream 100 bases:

>100_bases
TTTTAAAAATAAATAAATTATTATTTAATGGTTAATTTTTATAAAATTAATTATAAAAATAACATTTACTAAATTCAAAG
AAAGAACAAAGCCTTATGAA

Product: purine-nucleoside phosphorylase

Products: NA

Alternate protein names: PNP [H]

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MTAHNQAKLGEIAKVVLMPGDPMRAKWIAETFLENAILVNEVRGMLCYTGTYKGKKISIMGHGMGIPSIGIYSYELYKFY
EVETIIRVGSTGSYKKDLNVNDVVLVEKSYSDSTFASLIGAQVGDDKVLLPSREVNNLIKNTAKELNLELSLATCHASDV
FYNNDFQTLDEIIHRTKSDCVDMESFGLFANAQILNKNAATLLTVSDSLITGDALSPAERANTFKKMVTLALESAIKLL

Sequences:

>Translated_239_residues
MTAHNQAKLGEIAKVVLMPGDPMRAK*IAETFLENAILVNEVRGMLCYTGTYKGKKISIMGHGMGIPSIGIYSYELYKFY
EVETIIRVGSTGSYKKDLNVNDVVLVEKSYSDSTFASLIGAQVGDDKVLLPSREVNNLIKNTAKELNLELSLATCHASDV
FYNNDFQTLDEIIHRTKSDCVDMESFGLFANAQILNKNAATLLTVSDSLITGDALSPAERANTFKKMVTLALESAIKLL
>Mature_238_residues
TAHNQAKLGEIAKVVLMPGDPMRAK*IAETFLENAILVNEVRGMLCYTGTYKGKKISIMGHGMGIPSIGIYSYELYKFYE
VETIIRVGSTGSYKKDLNVNDVVLVEKSYSDSTFASLIGAQVGDDKVLLPSREVNNLIKNTAKELNLELSLATCHASDVF
YNNDFQTLDEIIHRTKSDCVDMESFGLFANAQILNKNAATLLTVSDSLITGDALSPAERANTFKKMVTLALESAIKLL

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790844, Length=235, Percent_Identity=42.5531914893617, Blast_Score=169, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.1 [H]

Molecular weight: Translated: 26067; Mature: 25936

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAHNQAKLGEIAKVVLMPGDPMRAKIAETFLENAILVNEVRGMLCYTGTYKGKKISIMG
CCCCCHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEE
HGMGIPSIGIYSYELYKFYEVETIIRVGSTGSYKKDLNVNDVVLVEKSYSDSTFASLIGA
CCCCCCCCCEEEEEEHEEEEHEEEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHC
QVGDDKVLLPSREVNNLIKNTAKELNLELSLATCHASDVFYNNDFQTLDEIIHRTKSDCV
CCCCCEEEECCHHHHHHHHHHHHHCEEEEEEEEEECCCCEECCCHHHHHHHHHHHHHHHC
DMESFGLFANAQILNKNAATLLTVSDSLITGDALSPAERANTFKKMVTLALESAIKLL
CHHHCCCEECEEEECCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TAHNQAKLGEIAKVVLMPGDPMRAKIAETFLENAILVNEVRGMLCYTGTYKGKKISIMG
CCCCHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEE
HGMGIPSIGIYSYELYKFYEVETIIRVGSTGSYKKDLNVNDVVLVEKSYSDSTFASLIGA
CCCCCCCCCEEEEEEHEEEEHEEEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHC
QVGDDKVLLPSREVNNLIKNTAKELNLELSLATCHASDVFYNNDFQTLDEIIHRTKSDCV
CCCCCEEEECCHHHHHHHHHHHHHCEEEEEEEEEECCCCEECCCHHHHHHHHHHHHHHHC
DMESFGLFANAQILNKNAATLLTVSDSLITGDALSPAERANTFKKMVTLALESAIKLL
CHHHCCCEECEEEECCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]