Click here to switch to the map view.

The map label for this gene is ygfA [C]

Identifier: 126701079

GI number: 126701079

Start: 4050029

End: 4050598

Strand: Direct

Name: ygfA [C]

Synonym: CD3456

Alternate gene names: 126701079

Gene position: 4050029-4050598 (Clockwise)

Preceding gene: 126701076

Following gene: 126701142

Centisome position: 94.4

GC content: 27.54

Gene sequence:

>570_bases
ATGAAAAAAGAATTTAGAAAAAAAGTTATTGAATCAAGAAAAAATAAGAGTGCAAACTTTGTACTTAGTAATTCAAATTT
AATAACTGAAAAATTACTTCAAATGGAAGATATAAGAAATGCAACTAATATAATGCTTTATCTAAATTTTAACAATGAAG
TTCAAACAGATAATTTAATCAAAAAACTTTTGTCTCTAAAGAAAATAGTATCAAGTCCCATCACAATAAAAGAAAATCAT
ACATTAATCCCTACTCAAATAACAGATTTAAAAGAGGGATTGAGAATTGGAGCATATGGAATAAGAGAACCTAACGAAAA
ATCACCTACAATTGATATTAAGGCCTTAGATGTTGTAATTGTACCAGCTGTAGCATATGATATACATTGCTATAGATTAG
GATATGGTGGAGGATTTTATGATAGATTTTTAGAAAACTTAAGAAAAGATGCTATAACTATCGGCATAGCATTTGACTTC
CAGATATTCGATTCTATTCCAAAAGAAACTCATGATGCACAATTAGACTACATAGTTACTGAAACTAGAATTATCACTCC
AAATAGTTAG

Upstream 100 bases:

>100_bases
TTTACCCAAATATATTGCTTTATTACAATAAATTATACTAAAATTTATATTAAATACAATTGCTGTACACATTATAACAT
ATTAAGGGAGGAATTATTTT

Downstream 100 bases:

>100_bases
AATATTAAGTATTTCCAGACCCCATTTAATGTAGTAATAAATACTACTGTTAATATCTTACTTTATAAGCATTTTAAGTC
ATGGCTTTTACAACAATAAG

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MKKEFRKKVIESRKNKSANFVLSNSNLITEKLLQMEDIRNATNIMLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENH
TLIPTQITDLKEGLRIGAYGIREPNEKSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
QIFDSIPKETHDAQLDYIVTETRIITPNS

Sequences:

>Translated_189_residues
MKKEFRKKVIESRKNKSANFVLSNSNLITEKLLQMEDIRNATNIMLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENH
TLIPTQITDLKEGLRIGAYGIREPNEKSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
QIFDSIPKETHDAQLDYIVTETRIITPNS
>Mature_189_residues
MKKEFRKKVIESRKNKSANFVLSNSNLITEKLLQMEDIRNATNIMLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENH
TLIPTQITDLKEGLRIGAYGIREPNEKSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
QIFDSIPKETHDAQLDYIVTETRIITPNS

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=193, Percent_Identity=24.3523316062176, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI1789278, Length=163, Percent_Identity=29.4478527607362, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17510857, Length=172, Percent_Identity=27.3255813953488, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321031, Length=184, Percent_Identity=27.7173913043478, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI161077430, Length=192, Percent_Identity=27.0833333333333, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: NA

Molecular weight: Translated: 21605; Mature: 21605

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEFRKKVIESRKNKSANFVLSNSNLITEKLLQMEDIRNATNIMLYLNFNNEVQTDNLI
CCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHH
KKLLSLKKIVSSPITIKENHTLIPTQITDLKEGLRIGAYGIREPNEKSPTIDIKALDVVI
HHHHHHHHHHCCCCEECCCCEECCCCHHHHHCCCEECEECCCCCCCCCCEEEEEEEEEEE
VPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDFQIFDSIPKETHDAQLDYIVT
EEEHEEEEEEEEEECCCCHHHHHHHHHHHCEEEEEEEEEHHHHHCCCCCCCCCEEEEEEE
ETRIITPNS
EEEEECCCC
>Mature Secondary Structure
MKKEFRKKVIESRKNKSANFVLSNSNLITEKLLQMEDIRNATNIMLYLNFNNEVQTDNLI
CCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHH
KKLLSLKKIVSSPITIKENHTLIPTQITDLKEGLRIGAYGIREPNEKSPTIDIKALDVVI
HHHHHHHHHHCCCCEECCCCEECCCCHHHHHCCCEECEECCCCCCCCCCEEEEEEEEEEE
VPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDFQIFDSIPKETHDAQLDYIVT
EEEHEEEEEEEEEECCCCHHHHHHHHHHHCEEEEEEEEEHHHHHCCCCCCCCCEEEEEEE
ETRIITPNS
EEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]