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The map label for this gene is agaA [H]

Identifier: 126701076

GI number: 126701076

Start: 4045779

End: 4046933

Strand: Direct

Name: agaA [H]

Synonym: CD3453

Alternate gene names: 126701076

Gene position: 4045779-4046933 (Clockwise)

Preceding gene: 126701075

Following gene: 126701079

Centisome position: 94.3

GC content: 30.48

Gene sequence:

>1155_bases
TTGAAAAGTTTTATTTATGCAGATAAATTTTTTATGAAACATGGAATCAAAGAAAAAGGTTACCTTAGTATAATTAATGG
CAAATTCGGTGAATTTCAACAAGAAAGACCTAATATTACTGATAATGTTATAGATTTTTCAGGTAAATATATTGCTCCTG
GCTTAGTTGATACTCACATTCACGGTCTTTTAGGTGCAGATGTCATGGACAATACATTTGAAGCAATAAACACAATTTCA
AAAGGCTTATTAAAATATGGAGTAACATCTTTCCTACCTACAACTTTAACTGATTCTGTAGATACACTAAGTGATTCTGT
AGAAAATATAAGCAATAGCTTCAATCGAGTTGAGGGTGCAAAAATACAAGGGATTTATTTAGAAGGTCCATTTTTTACAG
AAAAATATAAGGGCGCTCAAAATGAAAAATATTTTAAAGACCCTGACATCAATATATTAAAATTATGGCAAAAAAAATCG
AAAAATTTAATAAGAAAAATAGCAATTGCTCCAGAACGTAAAGGTTCAATAGAATTAACAAGATATGCAACTAAAAATAA
TATATCAGTTTCTCTTGGTCATAGTTCAGCTACATTTGAGCAAGTTAAACAAGTCGTTAATTCAGGTGCTAAAGTGTTTG
TACATACATATAATGGGATGAGTCCTTTAAATCATAGAGAACCTGGAATGGTTGGGGCTGCTATGGTACTAAAAGATACT
TATGCTGAATTAATTTGTGATGGTCATCATGTAAGCCCAATAGCTGTTAAAATAATGATGGATGCTAAGTCTAGTAATAA
CATAGCTTTAATTACAGATTGTATGAGAGCTGGTGCTATGGAGGATGGAAAATATACTCTTGGTAAGTTTAATGTAAATG
TAAAAAATAGTGTTGCAAGATTAAATAGTGGGAGTTTAGCTGGAAGTGTATTAACTATGGACAAGGCTGTGAGAAATATA
GTTGATTGGAACATATCAACTTTAGAAGATGCAATAAAAATGGCTACATATGTCCCTGCTTTAAGTTGTAATATTGATAA
TGTCTGTGGCTCTATATATCAAGGTATGGATGCAGATTTTATAGTAACAGATAATGACTTTAATATACACGAAACTTATA
TAAATGGTATCTGTAAGTACAAAGTTAATAAATAG

Upstream 100 bases:

>100_bases
GTAAGACATGTAAGATAGTAAGTTAAATAGCTTTCAAGAAAATAGAATGATATTATAAACGTCAATGCCACAATGATAGT
ATAATTATAAGGAGGTTATT

Downstream 100 bases:

>100_bases
GTTCAATATAAGGTTATGGAGGCTGTCTAAAAAGAGTCTGGAAATATTTAAAGTTATTTCTCCAAAATCTGATTTAACAC
TTTTATTTCCATATCGTTAA

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNITDNVIDFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTIS
KGLLKYGVTSFLPTTLTDSVDTLSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQKKS
KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYNGMSPLNHREPGMVGAAMVLKDT
YAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMRAGAMEDGKYTLGKFNVNVKNSVARLNSGSLAGSVLTMDKAVRNI
VDWNISTLEDAIKMATYVPALSCNIDNVCGSIYQGMDADFIVTDNDFNIHETYINGICKYKVNK

Sequences:

>Translated_384_residues
MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNITDNVIDFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTIS
KGLLKYGVTSFLPTTLTDSVDTLSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQKKS
KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYNGMSPLNHREPGMVGAAMVLKDT
YAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMRAGAMEDGKYTLGKFNVNVKNSVARLNSGSLAGSVLTMDKAVRNI
VDWNISTLEDAIKMATYVPALSCNIDNVCGSIYQGMDADFIVTDNDFNIHETYINGICKYKVNK
>Mature_384_residues
MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNITDNVIDFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTIS
KGLLKYGVTSFLPTTLTDSVDTLSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQKKS
KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYNGMSPLNHREPGMVGAAMVLKDT
YAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMRAGAMEDGKYTLGKFNVNVKNSVARLNSGSLAGSVLTMDKAVRNI
VDWNISTLEDAIKMATYVPALSCNIDNVCGSIYQGMDADFIVTDNDFNIHETYINGICKYKVNK

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=395, Percent_Identity=28.1012658227848, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI224922791, Length=388, Percent_Identity=28.6082474226804, Blast_Score=173, Evalue=3e-43,
Organism=Escherichia coli, GI1786892, Length=335, Percent_Identity=27.4626865671642, Blast_Score=142, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17553768, Length=390, Percent_Identity=29.2307692307692, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI19920392, Length=351, Percent_Identity=33.048433048433, Blast_Score=181, Evalue=6e-46,
Organism=Drosophila melanogaster, GI281361140, Length=365, Percent_Identity=32.0547945205479, Blast_Score=178, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 42454; Mature: 42454

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNITDNVIDFSGKYIAPGLVDTHI
CCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHCCCCCCCHHHCCCCCEECCCHHHHHH
HGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDTLSDSVENISNSFNRVEGA
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
KIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQKKSKNLIRKIAIAPERKGSIELT
EEEEEEEECCEEHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
RYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYNGMSPLNHREPGMVGAAMVLKDT
EEECCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHH
YAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMRAGAMEDGKYTLGKFNVNVKNSVAR
HHHHHCCCCCCCCEEEEEEEECCCCCCEEEEEHHHHCCCCCCCCEEEEEEEEEHHHHHHH
LNSGSLAGSVLTMDKAVRNIVDWNISTLEDAIKMATYVPALSCNIDNVCGSIYQGMDADF
CCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEECCHHHHHHHHHCCCCCCE
IVTDNDFNIHETYINGICKYKVNK
EEECCCCCCHHHHHCCEEEEEECC
>Mature Secondary Structure
MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNITDNVIDFSGKYIAPGLVDTHI
CCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHCCCCCCCHHHCCCCCEECCCHHHHHH
HGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDTLSDSVENISNSFNRVEGA
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
KIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQKKSKNLIRKIAIAPERKGSIELT
EEEEEEEECCEEHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
RYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYNGMSPLNHREPGMVGAAMVLKDT
EEECCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHH
YAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMRAGAMEDGKYTLGKFNVNVKNSVAR
HHHHHCCCCCCCCEEEEEEEECCCCCCEEEEEHHHHCCCCCCCCEEEEEEEEEHHHHHHH
LNSGSLAGSVLTMDKAVRNIVDWNISTLEDAIKMATYVPALSCNIDNVCGSIYQGMDADF
CCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEECCHHHHHHHHHCCCCCCE
IVTDNDFNIHETYINGICKYKVNK
EEECCCCCCHHHHHCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969210 [H]