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The map label for this gene is treR [H]

Identifier: 126700707

GI number: 126700707

Start: 3591394

End: 3592116

Strand: Direct

Name: treR [H]

Synonym: CD3090

Alternate gene names: 126700707

Gene position: 3591394-3592116 (Clockwise)

Preceding gene: 126700700

Following gene: 126700708

Centisome position: 83.71

GC content: 28.63

Gene sequence:

>723_bases
ATGGCTAAAAATAAATTTTCAGAGATATATGAAGTATTGAAAGAGGAAATACTTGATGGTAAATATACAAGTAATATGAT
GCTGCCTACTGAACTTCAACTTATTGAAAGGTTTTCATGTAGCAGAAACACTGTACGTAGAGCAATTTCTCAATTAAACA
CAGAAGGATATGTTCAAAGTATAAAAGGCAAGGGTGTTGTAGTGTTAGAAAATAGTTGTTCTAATGATTTTTTTCTAAAT
ATGCACAATTTCAAAGGTGTAGAATCGATTGTAGAAGATAAAAAGGTTAATACTGCTACTAGTGTTCTCAACTTCAGCAA
AATCTTAATTGATAATAAGTTATCTAAAAAGACAGGTTTTAAAGTTGGTAGTGAAGTATATTACCTTCACAGACTAAGAT
ATATTGATAACATACCTAAAATTCTCGACATTAACTATTTTCTATGTAGTATAGTTAAAGACCTTGATGTTTCTATAGCA
CAAGGCTCTATTTATAAATATATAGAAGAGTGTCTAGGTACAAAAATTGTTTCATCCAGAAAGATATTTAAAATTGAAAA
AGCTACAGAACTTGAGTTAAAAACGCTACCTCTAAATGATTATAATTGTGTTGGTGTTATTAAAAATAGTGTATATACTG
ATGATGGAAAGCTTTTTGAATATACTGAATCAAAGCATACACCTGAAACATTTGTATTCATGGATGTTACTCAAAGATAT
TAA

Upstream 100 bases:

>100_bases
TGATTCTATTTTCACTATACATGTCTAAACACATTTGATATAATTTGTTCATATCAGTTCAATAATATTACTAAAGACCT
TTAAGGAGGGATAGGGGTAT

Downstream 100 bases:

>100_bases
AAAAATTATGTTTAATTAAACATAATTTTTTTACGTTTAGACACTTTATCCCATACTAACCTCACTATTCTATATACAAT
TATATGTTTATACAAATAAT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNTVRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLN
MHNFKGVESIVEDKKVNTATSVLNFSKILIDNKLSKKTGFKVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIA
QGSIYKYIEECLGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKLFEYTESKHTPETFVFMDVTQRY

Sequences:

>Translated_240_residues
MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNTVRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLN
MHNFKGVESIVEDKKVNTATSVLNFSKILIDNKLSKKTGFKVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIA
QGSIYKYIEECLGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKLFEYTESKHTPETFVFMDVTQRY
>Mature_239_residues
AKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNTVRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLNM
HNFKGVESIVEDKKVNTATSVLNFSKILIDNKLSKKTGFKVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIAQ
GSIYKYIEECLGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKLFEYTESKHTPETFVFMDVTQRY

Specific function: Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate, which probably acts as an inducer [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=239, Percent_Identity=27.1966527196653, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI87082252, Length=211, Percent_Identity=27.9620853080569, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1790118, Length=217, Percent_Identity=21.6589861751152, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR012770
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27608; Mature: 27477

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNTVRRAISQLNTEGYVQS
CCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHH
IKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSVLNFSKILIDNKLSKKTGF
HCCCEEEEECCCCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHCCC
KVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIAQGSIYKYIEECLGTKIVSSR
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHCCHHHCCC
KIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKLFEYTESKHTPETFVFMDVTQRY
CEEEECCCCCEEEEEECCCCCCEEEEEECCEECCCCCEEEECCCCCCCCEEEEEEECCCC
>Mature Secondary Structure 
AKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNTVRRAISQLNTEGYVQS
CCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHH
IKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSVLNFSKILIDNKLSKKTGF
HCCCEEEEECCCCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHCCC
KVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIAQGSIYKYIEECLGTKIVSSR
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHCCHHHCCC
KIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKLFEYTESKHTPETFVFMDVTQRY
CEEEECCCCCEEEEEECCCCCCEEEEEECCEECCCCCEEEECCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8917076; 8969503; 9384377; 7651129; 8755887 [H]