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The map label for this gene is mngB [H]

Identifier: 126700188

GI number: 126700188

Start: 2970721

End: 2973399

Strand: Direct

Name: mngB [H]

Synonym: CD2569

Alternate gene names: 126700188

Gene position: 2970721-2973399 (Clockwise)

Preceding gene: 126700187

Following gene: 126700212

Centisome position: 69.24

GC content: 28.33

Gene sequence:

>2679_bases
ATGAAAAAGACAAAAGTACATGTAGTTCCACACAGTCATTGGGATAGAGAATGGTATTTTACAACATCAAGGTCAAAAAT
ATATTTAATGAAAGATTTTCAAGATATATTAGACATATTGGAAGAAAAAGAAGACTTTAAATACTTTACTATGGATGCAC
AAGCTTCTCTCTTAGATGATTATTTAAAATGGAGACCTCAGGATGAATATAGAATAAGAGATTTAGTTCAAAGAAGAAGA
TTAGTTATTGGACCTTGGTATACTCAAACAGACCAATTGGTTATATCAGGAGAATCTATAATTAGAAACCTTTACTATGG
AATAGATAGATGCAATGAATTTGGTGAACCTATGAGGGTTGGATATGTACCAGATTCTTTTGGGCAATCAGCTCAAATGC
CACAAATATACAGAGGTTTTGGAATAGATAGTTCATTATTTTGGCGTGGAGTTTCTGATGATATGGTAGATACAACAGAG
TTTATATGGAAAGGTTCTGATGGTTCAAAAGTATTAGCAGTTCAAATACCATTTGGTTATTACTATGGAGGTAATATACC
AGAAGATGATTCTGATTTAAAAGAATATTTAAAAGATATAATCGGAAAACTTAAGGTTAAAGCTTCTACTAATAACGTAT
ATTTTCCAAATGGATTTGACCAAGCACCAATAAGAAAAAACCTTCCTGATATATTAAAAAAAGCTAATGAAATAGATAAT
GAAAATGAATACGAAATAAGTGATATAGAAAACTATATAGATTCAGTAAGAAATGAAAGAAATGAATTTACAGAGCTTAA
AGGTGAATTTTTAAATGCTAAACATATGAGAATACACAAATCCATATTCTCCTCAAGGTCAGACCTTAAAATAATGAATA
ACAAATTAGAAAATTATATTACAAATGTACTTGAACCATTATTAACATTAAGTTATTCACTTGGAAATGAATACCCTCAC
CTAGTTATAAAAGATATATGGAAACTTATGTTTGAAAATGCAGCTCATGACAGCATAGGTTCTTGTAATAGTGACACAAC
AAATGAGGATGTATACACAAGATACAAACAAGCCAGAGATTTGAGTATAAATTTATTAGATTTGCATATGAGACTTATAA
GTACTCAAATCAAAAATAATAATGAAGAAATAACATTAACAGTATTCAATGGATTCCCAGAAGTCAGAAATGAAGTTGTA
GAATTTGATACTTATATTCCAGGTCAAGATTTTGTGATAAAGAATAAAAATGGAAAAATTCTTAATTATATAATAAAAGA
AAAAGAAGATATTACAAATTATATATTAACTCAAACAATAAGATTAAACCCAAGTAAAAAAATATATATACCCAAAACTG
TATATAGAGCAAAAATTGCACTTTCAGTAAAAGATATACCACCAATGGGATATACTCAACTAGTTTTTGAATTGGATACT
AAAAATAAATGTGAAATAGAAACAAGTAATTGCAAGGAAATAGAAAACAAATACTACAAAATAACAGCCAATAAAAATGG
TTCATTAGAAATATTAGATAAAGAATCTAATAAGACTTATAAAAACCAAGCTGTAATTGAAGACAATGGAGATGATGGAG
ATTCATACAACTATTCTCCTCCAAGAAAAGATATTTATGTTTCATCTTTAGATTCTGTATCTTCAGTAGAAGTGCTAAAA
TCAAACATTCAAGAAGAAATGATACTTAAATATTCATTGACCATACCAACTTCACTGGAAGAAAGGGCTATAGGTAAAGT
TTCTGTGAAAATGCCAGTAACAATGAAAATCACCTTAGAACCTAAAGAACAAATAATTAAGTTTAATGTTAATATAAAAA
ATAACCAAGCACTATCTCATAGAGTAAGAGTTTTATTTAATACAGAAATAGCATCTAAGTTTTCTATAGCAGATCAACAA
TTTGGAATAATACAAAGACCAACAGTATTAGAAAAAGACCTTGCATTGTGGAAAAGAGACAATTACTCATGGCAAGAAAA
ACCTATAACTATCGAACCAATGCAAAGTTTTGTTACTTTAGAGGATGGACAAAGAGGAATAGCATTAATAACTGGTTGTG
TAAGAGAATATCAAATAGTTGGTGATAATTTAGATACAATAGCATTAACACTATTCAGGTCATTTGGATATATGGGAAGA
GAAAATTTACTTTATAGACCAGGAAGAGCTTCTGGAGAAAAAATAATAGCAACACCAGATGCACAATTACTTAAAGAGTT
AAACTTTGACTTTGGTCTTTACATATATAACAATAAATTTGATGAAGCAAATGTAGCTAATACAGCTAAGAGATTCTTAA
CACCTATACAAATATATGAATATGCTGATTTTTTAAATGGTAGACTTATATTTGCATTCAATGACGAAAAACAAATATAT
GAAAATGAATTTAGTTTGATGAATGTAAATAATTCAAATTTCACAGTAAGTGCAATAAAGAAAGAAGAAAAAGGAGATGG
AATTGTAGTTAGAATCTTCAATGGTATGAAAAATGAGGATGCTAAGGGAAGTCTTAACATCAATAAAAATGTCAATGATG
CTTATAGTGCAATGCTCGACGAAATCTATGATAATACTAGCAAGCTTAAAGTAAATACTAAAACTGTAGAGGTAAATTCT
TTATCACATTGTAAAGTACAAACAATAGTAATTAAATAA

Upstream 100 bases:

>100_bases
ATGAAATAGAGTTAGATATAATGTAAATTAAAAACTTAATTTTAGATAATTGAGAATTGAGTGTACTCTCAATTCTCAAT
TAAATTTTGGGAGGATTTTT

Downstream 100 bases:

>100_bases
TATAAAATAGCTTATACAAGATTTCAAAATAAATTGCTAGTACTATGTTAATAGTAAAGCCAGATATTATGCTATTTATA
AGCTCTGTAACACTAAATAA

Product: alpha-mannosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 892; Mature: 892

Protein sequence:

>892_residues
MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKEDFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRRR
LVIGPWYTQTDQLVISGESIIRNLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNGFDQAPIRKNLPDILKKANEIDN
ENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHMRIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPH
LVIKDIWKLMFENAAHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGFPEVRNEVV
EFDTYIPGQDFVIKNKNGKILNYIIKEKEDITNYILTQTIRLNPSKKIYIPKTVYRAKIALSVKDIPPMGYTQLVFELDT
KNKCEIETSNCKEIENKYYKITANKNGSLEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLK
SNIQEEMILKYSLTIPTSLEERAIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRVLFNTEIASKFSIADQQ
FGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLEDGQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGR
ENLLYRPGRASGEKIIATPDAQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLIFAFNDEKQIY
ENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYSAMLDEIYDNTSKLKVNTKTVEVNS
LSHCKVQTIVIK

Sequences:

>Translated_892_residues
MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKEDFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRRR
LVIGPWYTQTDQLVISGESIIRNLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNGFDQAPIRKNLPDILKKANEIDN
ENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHMRIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPH
LVIKDIWKLMFENAAHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGFPEVRNEVV
EFDTYIPGQDFVIKNKNGKILNYIIKEKEDITNYILTQTIRLNPSKKIYIPKTVYRAKIALSVKDIPPMGYTQLVFELDT
KNKCEIETSNCKEIENKYYKITANKNGSLEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLK
SNIQEEMILKYSLTIPTSLEERAIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRVLFNTEIASKFSIADQQ
FGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLEDGQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGR
ENLLYRPGRASGEKIIATPDAQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLIFAFNDEKQIY
ENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYSAMLDEIYDNTSKLKVNTKTVEVNS
LSHCKVQTIVIK
>Mature_892_residues
MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKEDFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRRR
LVIGPWYTQTDQLVISGESIIRNLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNGFDQAPIRKNLPDILKKANEIDN
ENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHMRIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPH
LVIKDIWKLMFENAAHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGFPEVRNEVV
EFDTYIPGQDFVIKNKNGKILNYIIKEKEDITNYILTQTIRLNPSKKIYIPKTVYRAKIALSVKDIPPMGYTQLVFELDT
KNKCEIETSNCKEIENKYYKITANKNGSLEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLK
SNIQEEMILKYSLTIPTSLEERAIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRVLFNTEIASKFSIADQQ
FGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLEDGQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGR
ENLLYRPGRASGEKIIATPDAQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLIFAFNDEKQIY
ENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYSAMLDEIYDNTSKLKVNTKTVEVNS
LSHCKVQTIVIK

Specific function: May hydrolyze mannosyl-D-glycerate to mannose-6- phosphate and glycerate [H]

COG id: COG0383

COG function: function code G; Alpha-mannosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 38 family [H]

Homologues:

Organism=Homo sapiens, GI46852164, Length=346, Percent_Identity=25.7225433526012, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI1786952, Length=860, Percent_Identity=34.3023255813954, Blast_Score=583, Evalue=1e-167,
Organism=Saccharomyces cerevisiae, GI6321282, Length=513, Percent_Identity=21.4424951267057, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011013
- InterPro:   IPR011330
- InterPro:   IPR011682
- InterPro:   IPR015341
- InterPro:   IPR000602 [H]

Pfam domain/function: PF09261 Alpha-mann_mid; PF01074 Glyco_hydro_38; PF07748 Glyco_hydro_38C [H]

EC number: NA

Molecular weight: Translated: 103136; Mature: 103136

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKEDFKYFTMDAQASLLDD
CCCCEEEEECCCCCCCEEEEEECCCEEEEHHHHHHHHHHHHCCCCCEEEEECCHHHHHHH
YLKWRPQDEYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIRNLYYGIDRCNEFGEPMRV
HHHCCCCCHHHHHHHHHHCCEEEECCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCEEE
GYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTEFIWKGSDGSKVLAVQIPFGY
ECCCCCCCCCCCCCHHHHCCCCCHHHEECCCCCCCCCCCHHEEECCCCCEEEEEEECCEE
YYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNGFDQAPIRKNLPDILKKANEIDN
EECCCCCCCHHHHHHHHHHHHHHEEEEECCCCEECCCCCCCCCCCCCCHHHHHHHHHCCC
ENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHMRIHKSIFSSRSDLKIMNNKLENYI
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
TNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENAAHDSIGSCNSDTTNEDVYTRYKQARD
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCC
LSINLLDLHMRLISTQIKNNNEEITLTVFNGFPEVRNEVVEFDTYIPGQDFVIKNKNGKI
CEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCCE
LNYIIKEKEDITNYILTQTIRLNPSKKIYIPKTVYRAKIALSVKDIPPMGYTQLVFELDT
EEHHHHCHHHHHHHHHHEEEEECCCCEEEECHHEEEEEEEEEEECCCCCCCEEEEEEECC
KNKCEIETSNCKEIENKYYKITANKNGSLEILDKESNKTYKNQAVIEDNGDDGDSYNYSP
CCCEEEECCCHHHHCCCEEEEEECCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCCC
PRKDIYVSSLDSVSSVEVLKSNIQEEMILKYSLTIPTSLEERAIGKVSVKMPVTMKITLE
CCCCEEEECCCCHHHHHHHHHCCHHHEEEEEEEECCCCHHHHCCCEEEEEEEEEEEEEEC
PKEQIIKFNVNIKNNQALSHRVRVLFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRD
CCCEEEEEEEEECCCCHHHHEEEEEEECCHHHHHCCCHHHCCCCCCCCHHHHHHHHHCCC
NYSWQEKPITIEPMQSFVTLEDGQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGR
CCCCCCCCEEEECHHHEEEECCCCCCHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCCC
ENLLYRPGRASGEKIIATPDAQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYE
CCCEECCCCCCCCEEEECCCHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCCHHHHHH
YADFLNGRLIFAFNDEKQIYENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNED
HHHHHCCEEEEEECCCHHHHCCCEEEEEECCCCEEEEEEECCCCCCCEEEEEECCCCCCC
AKGSLNINKNVNDAYSAMLDEIYDNTSKLKVNTKTVEVNSLSHCKVQTIVIK
CCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCEEEEEEEC
>Mature Secondary Structure
MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKEDFKYFTMDAQASLLDD
CCCCEEEEECCCCCCCEEEEEECCCEEEEHHHHHHHHHHHHCCCCCEEEEECCHHHHHHH
YLKWRPQDEYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIRNLYYGIDRCNEFGEPMRV
HHHCCCCCHHHHHHHHHHCCEEEECCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCEEE
GYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTEFIWKGSDGSKVLAVQIPFGY
ECCCCCCCCCCCCCHHHHCCCCCHHHEECCCCCCCCCCCHHEEECCCCCEEEEEEECCEE
YYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNGFDQAPIRKNLPDILKKANEIDN
EECCCCCCCHHHHHHHHHHHHHHEEEEECCCCEECCCCCCCCCCCCCCHHHHHHHHHCCC
ENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHMRIHKSIFSSRSDLKIMNNKLENYI
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
TNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENAAHDSIGSCNSDTTNEDVYTRYKQARD
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCC
LSINLLDLHMRLISTQIKNNNEEITLTVFNGFPEVRNEVVEFDTYIPGQDFVIKNKNGKI
CEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCCE
LNYIIKEKEDITNYILTQTIRLNPSKKIYIPKTVYRAKIALSVKDIPPMGYTQLVFELDT
EEHHHHCHHHHHHHHHHEEEEECCCCEEEECHHEEEEEEEEEEECCCCCCCEEEEEEECC
KNKCEIETSNCKEIENKYYKITANKNGSLEILDKESNKTYKNQAVIEDNGDDGDSYNYSP
CCCEEEECCCHHHHCCCEEEEEECCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCCC
PRKDIYVSSLDSVSSVEVLKSNIQEEMILKYSLTIPTSLEERAIGKVSVKMPVTMKITLE
CCCCEEEECCCCHHHHHHHHHCCHHHEEEEEEEECCCCHHHHCCCEEEEEEEEEEEEEEC
PKEQIIKFNVNIKNNQALSHRVRVLFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRD
CCCEEEEEEEEECCCCHHHHEEEEEEECCHHHHHCCCHHHCCCCCCCCHHHHHHHHHCCC
NYSWQEKPITIEPMQSFVTLEDGQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGR
CCCCCCCCEEEECHHHEEEECCCCCCHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCCC
ENLLYRPGRASGEKIIATPDAQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYE
CCCEECCCCCCCCEEEECCCHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCCHHHHHH
YADFLNGRLIFAFNDEKQIYENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNED
HHHHHCCEEEEEECCCHHHHCCCEEEEEECCCCEEEEEEECCCCCCCEEEEEECCCCCCC
AKGSLNINKNVNDAYSAMLDEIYDNTSKLKVNTKTVEVNSLSHCKVQTIVIK
CCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 9063979 [H]