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The map label for this gene is yycF [H]

Identifier: 126699391

GI number: 126699391

Start: 2063607

End: 2064341

Strand: Direct

Name: yycF [H]

Synonym: CD1782

Alternate gene names: 126699391

Gene position: 2063607-2064341 (Clockwise)

Preceding gene: 126699390

Following gene: 126699392

Centisome position: 48.1

GC content: 29.52

Gene sequence:

>735_bases
ATGGTTAATATTATACTCAATTGGAGGTTTTATTTTATGAAGGAAAAGATACTTATACTAGAAGATGAAATTGGTATTAG
AAGTTTTGTTAGTATAAACTTAAAAAGGGAAGGCTATGAAATAGTTGAGGCAGGTACTGGAAGAGAAGCTATAGAAAAAA
TGACAACAGAAAAGGATATTACAATAGCTCTTTTAGATGTAATGCTTCCAGATATAAGTGGTATAGAAGTATGTAAATTT
ATAAGGGAGAATTTTGACCAAGTAGGTATAATAATGCTTACTGCTAAAGCTCAAGAAGATGATAAAATAGAAGGATTTAT
CTCAGGAGCAGATGATTACATCATAAAACCATTTAGTATAAAAGAGCTTTTAGTCAGAGTTTCTGCTCTTCTTAGAAGAG
TAGCAAAGGATGATTCAAGTGTTAAGTCGAGTGAGATAGTTTCTCCACCATTTATACTTGATATAGACAAAAGAAAATTA
TTTAAAAATGGAAAGGAAATTGAGCTTACACCAACTGAATTTTCAATAGTGAAATATCTAATATCAAATGCTAAGCAGTC
GTTAAGTAGAGACCAGATATTAGACGAAGTATGGGGAACTAACTATTTATATGATTTTAAAATAGTAGATGTAAATATAA
GAAGGATAAGAAATAAAATAGAAGATGACCCATCAAAACCAAAATATATACAAACTATTTGGGGTTATGGATACTGTTTT
AGAAAGGAAGAATAA

Upstream 100 bases:

>100_bases
AGCGATGAATATACTTTCTTACTAGTTGTAAACAATGCAAATGAAATGGATAAGCTAGATATGACTATAGACGCATTAAA
AGAATATTTCTCATTAATAT

Downstream 100 bases:

>100_bases
TAGTGTTACATTTTGAAGGTCTGAGAAAAAAAGTAATAAAAAACTATTTTATAATAATTATTATAATGGTTACTCTGTTT
GAAGGATTGTTCATGTTTTA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MVNIILNWRFYFMKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTTEKDITIALLDVMLPDISGIEVCKF
IRENFDQVGIIMLTAKAQEDDKIEGFISGADDYIIKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKL
FKNGKEIELTPTEFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYIQTIWGYGYCF
RKEE

Sequences:

>Translated_244_residues
MVNIILNWRFYFMKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTTEKDITIALLDVMLPDISGIEVCKF
IRENFDQVGIIMLTAKAQEDDKIEGFISGADDYIIKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKL
FKNGKEIELTPTEFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYIQTIWGYGYCF
RKEE
>Mature_244_residues
MVNIILNWRFYFMKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTTEKDITIALLDVMLPDISGIEVCKF
IRENFDQVGIIMLTAKAQEDDKIEGFISGADDYIIKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKL
FKNGKEIELTPTEFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYIQTIWGYGYCF
RKEE

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=36.4035087719298, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1786599, Length=231, Percent_Identity=36.3636363636364, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=36.4035087719298, Blast_Score=143, Evalue=8e-36,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=34.070796460177, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=36.4444444444444, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=32.4444444444444, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=35.3448275862069, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=32.1428571428571, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=29.6943231441048, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=33.9130434782609, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=29.8701298701299, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=29.5652173913043, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=28.4444444444444, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=26.2931034482759, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=32.4074074074074, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28295; Mature: 28295

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNIILNWRFYFMKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTTEKDI
CEEEEEEEEEEEEECEEEEEECCCCCEEEEEEEEECCCEEEEECCCCHHHHHHHCCCCCH
TIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYIIKPFSI
HEEEHHHHCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHEEECCCCCEEECCCCH
KELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPTEFSIVKYL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHCCCCEEEECCCHHHHHHHH
ISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYIQTIWGYGYCF
HHHHHHHHHHHHHHHHHCCCCEEEEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHCCEEEE
RKEE
ECCC
>Mature Secondary Structure
MVNIILNWRFYFMKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTTEKDI
CEEEEEEEEEEEEECEEEEEECCCCCEEEEEEEEECCCEEEEECCCCHHHHHHHCCCCCH
TIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYIIKPFSI
HEEEHHHHCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHEEECCCCCEEECCCCH
KELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPTEFSIVKYL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHCCCCEEEECCCHHHHHHHH
ISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYIQTIWGYGYCF
HHHHHHHHHHHHHHHHHCCCCEEEEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHCCEEEE
RKEE
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]