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The map label for this gene is vanY [H]

Identifier: 126699231

GI number: 126699231

Start: 1885100

End: 1885906

Strand: Direct

Name: vanY [H]

Synonym: CD1627

Alternate gene names: 126699231

Gene position: 1885100-1885906 (Clockwise)

Preceding gene: 126699230

Following gene: 126699232

Centisome position: 43.94

GC content: 28.75

Gene sequence:

>807_bases
ATGATGAATAATATTTTATTAGATAAAAATAAAGAAGATAAAATGACAAATACTATCTTATTGACTAAAGATAAAGTTTA
TGATGGGAATCTAATTCTAGTAAATGCTTTTTTACCAGTTAAAACATCTGAAGATATAGATTTAATTCCTGTAGATACAA
GGTTTCCAAGTATTCTTATGAAACGTGAAGCTACAAACATTTTACAAAATATTTTAAAAAGTATATGTGGAATAAATGAA
ATAGTACCTGTAAGTGGATATCGTACTGCAGAAGAACAACAAGATATATATTCAAGTTCTCTGCGTGACAATGGAAAAGA
CTTTACTAAAAAGTTTGTAGCACTTCCAAATCACAGTGAACATCAGACAGGGCTTGCTATTGATTTAGGGTTAAAGAAAG
AAGTTATAGATTTTATCTGCCCTGAATTTCCTTATAATGGTATTTGTAATGAGTTTCGTAAGGCAGCACTACATTATGGT
TTTATAGAGCGTTATCAGTGTAAAAAAGAAGAAATAACAGGAATATCTCAAGAACCATGGCATTTTCGTTATGTGGGATA
TCCGCATTCTGAGATTATCAATAAAATGAATCTCGCTCTTGAAGAATATATAGAATATATTAAGAGATTTTCGTATACAA
ATTGTTTAAAAATAGAAGATAAAGAAAAAATTATAGAAATCTTTTATGTGCCTATTCATACTAAAGAAGAAGTGAGAATC
TCTATACCTGAACAATGTGTATATCAAATATCGGGTAACAATAAGGATGGTTTTATTGTGACATTTTGGAGAAATAGAAA
GGACTAA

Upstream 100 bases:

>100_bases
TTCCTGGCTTTACTTCTCATAGTCGTTATCCAAATATGATGAAAGGTATTGGACTGTCTTTTGAAGAAATATTGGACAAG
ATAATTGAGGTGTACATAAA

Downstream 100 bases:

>100_bases
GAAATGGAGGAACAAGAATGATTAGGAATAAATCTTATGCAGGGCTTGATTATTTTAGGATTATAGCTGCATTACTTATA
ATTGCAATTCATACATCTCC

Product: D-alanyl-D-alanine carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSEDIDLIPVDTRFPSILMKREATNILQNILKSICGINE
IVPVSGYRTAEEQQDIYSSSLRDNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKIEDKEKIIEIFYVPIHTKEEVRI
SIPEQCVYQISGNNKDGFIVTFWRNRKD

Sequences:

>Translated_268_residues
MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSEDIDLIPVDTRFPSILMKREATNILQNILKSICGINE
IVPVSGYRTAEEQQDIYSSSLRDNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKIEDKEKIIEIFYVPIHTKEEVRI
SIPEQCVYQISGNNKDGFIVTFWRNRKD
>Mature_268_residues
MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSEDIDLIPVDTRFPSILMKREATNILQNILKSICGINE
IVPVSGYRTAEEQQDIYSSSLRDNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKIEDKEKIIEIFYVPIHTKEEVRI
SIPEQCVYQISGNNKDGFIVTFWRNRKD

Specific function: Vancomycin-inducible, penicillin-resistant, DD- carboxypeptidase that hydrolyzes depsipeptide- and D-alanyl-D- alanine-containing peptidoglycan precursors. Insensitive to beta- lactams [H]

COG id: COG1876

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M15B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003709 [H]

Pfam domain/function: PF02557 VanY [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 31276; Mature: 31276

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSEDIDLIPVDTRFPSILM
CCCCEECCCCCCCCCCEEEEEEECCEECCCEEEEEEEECCCCCCCCEEEEECCCCHHHHH
KREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLRDNGKDFTKKFVALPNHSE
HHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCC
HQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYGFIERYQCKKEEITGISQEPW
CCCCEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCC
HFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKIEDKEKIIEIFYVPIHTKEEVRI
EEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEEEECCCCCCEEE
SIPEQCVYQISGNNKDGFIVTFWRNRKD
ECCHHEEEEECCCCCCCEEEEEECCCCC
>Mature Secondary Structure
MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSEDIDLIPVDTRFPSILM
CCCCEECCCCCCCCCCEEEEEEECCEECCCEEEEEEEECCCCCCCCEEEEECCCCHHHHH
KREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLRDNGKDFTKKFVALPNHSE
HHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCC
HQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYGFIERYQCKKEEITGISQEPW
CCCCEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCC
HFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKIEDKEKIIEIFYVPIHTKEEVRI
EEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEEEECCCCCCEEE
SIPEQCVYQISGNNKDGFIVTFWRNRKD
ECCHHEEEEECCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1398115; 8380148 [H]