BacMap

Definition	Clostridium difficile 630 chromosome, complete genome.
Accession	NC_009089
Length	4,290,252

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The map label for this gene is steT [H]

Identifier: 126699159

GI number: 126699159

Start: 1802604

End: 1803947

Strand: Direct

Name: steT [H]

Synonym: CD1555

Alternate gene names: 126699159

Gene position: 1802604-1803947 (Clockwise)

Preceding gene: 126699158

Following gene: 126699160

Centisome position: 42.02

GC content: 33.56

Gene sequence:

>1344_bases
ATGAGGAGGAAAAAAATGGGAAGTAATGAACTGAAAAAGACTCTTGGCGTATCAGCAGCATTATCAACTGTTGTTGGTTC
CGTTATAGGAGCGGGCGTATTTTTTAAACCACAAGCAGTCTATACATTAACTGGAGGAGCTCCAGGTCTTGGTATATTGG
CATGGTTAATAGCTGGAATCATAACTATAACAGCTGGTCTTACAGCTGCAGAGGTATCAGTTGCGATACCAAAAACTGGT
GGAATGATGGTATATATAAAAGAAATTTATGGAGAAAAATTAGGTTTTTTAACTGGATGGATGCAAATTGTATTATTTTA
TCCAGGGATGATGGCAGCATTAGGTGTTATATTTGGAGAACAAGCATCAGCACTAATTGGTAGTCCATCACTTTTACTTC
CAATAGCAATTGGAATTATAATAATAGTTGCAGGGCTTAATATGTTAGGTTCAAAAACTGGAGGAGTCATACAAACTGTT
TCTACAATTTGTAAGTTAATACCACTTATTTTAATAATGGTTGTTGGATTTATTAAAGGTGGTGGAAATAATCCAATACT
TACACCTATGGTTGGTGAAGGATTAAGCCTGGGTAGTGTACTAGGTCAAGTTTTAATTGCTATATTATTTGCTTTTGATG
GATGGATGAATGTTGGTACTTTAGCTGGAGAAATGAAGAATCCTGGAAAAGACCTTCCAAAAGCTATAATAGGTGGATTG
TCAGTTGTTATGGCTGTTTATTTTATAATAAATTTAGCGTATCTTTGGGTATTACCAGCTAATGAATTAGCAAATTATGC
TTCTCCTGCATCAGCAGTTGCTGAAGTTATATTTGGTTCAATGGGTGGAAAAATAATATCTGTAGGTATATTAATTTCAG
TGTTTGGAGCATTAAATGGATTTTTACTAACTGGTTCAAGGGTGGCATATACTTTAGCTACAGATAAGACTTTACCAAAG
TATGGTATATTTTCTAAATTAAATTCTGCTCAAGTTCCAGCAAATGCAATAGCATTAGTATCTGTTATTGCATCTATATA
TGCTTTGTCAGGTCAATTTAATTTATTAACTGACTTAGCTGTATTTGCTACTTGGATATTCTATGTATTAACTTTTATAG
GGGTTATGAAACTTAGAAAGACTCATCCAAATATACCAAGAGAGTATAAAGTTCCATTATATCCTATTGTTCCTATAATA
GCTATAGCAAGTGGTATATTTGTTGTAGTTAATCAATTGTGTTTTGCAGGTATGAAAACTACTATGATATCTATAGGAGG
TCTTGTAATAACAGCTATAGGCTTACCAGTGTATGCTTATATGACTAGAGGAGTAAAAAGATAA

Upstream 100 bases:

>100_bases
AGTAGAGTTTATTTTATTTTAATAAATAATAAAGCTATTTTTCTATATATTGGCATAATATATGCTTATTTAACTATGAA
ATTAAAATTAAATAGGATTA

Downstream 100 bases:

>100_bases
ACCAAGTAGTTTACAAATGCTTCATAATTAAAATAAAAGAGACTGTCTCAAATAGAGATAAGTCTCTTTTTTATTGTTAA
AATGGTAAAGATATGTTTAA

Product: amino acid permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MRRKKMGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPGLGILAWLIAGIITITAGLTAAEVSVAIPKTG
GMMVYIKEIYGEKLGFLTGWMQIVLFYPGMMAALGVIFGEQASALIGSPSLLLPIAIGIIIIVAGLNMLGSKTGGVIQTV
STICKLIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAGEMKNPGKDLPKAIIGGL
SVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSMGGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPK
YGIFSKLNSAQVPANAIALVSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIVPII
AIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGVKR

Sequences:

>Translated_447_residues
MRRKKMGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPGLGILAWLIAGIITITAGLTAAEVSVAIPKTG
GMMVYIKEIYGEKLGFLTGWMQIVLFYPGMMAALGVIFGEQASALIGSPSLLLPIAIGIIIIVAGLNMLGSKTGGVIQTV
STICKLIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAGEMKNPGKDLPKAIIGGL
SVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSMGGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPK
YGIFSKLNSAQVPANAIALVSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIVPII
AIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGVKR
>Mature_447_residues
MRRKKMGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPGLGILAWLIAGIITITAGLTAAEVSVAIPKTG
GMMVYIKEIYGEKLGFLTGWMQIVLFYPGMMAALGVIFGEQASALIGSPSLLLPIAIGIIIIVAGLNMLGSKTGGVIQTV
STICKLIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAGEMKNPGKDLPKAIIGGL
SVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSMGGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPK
YGIFSKLNSAQVPANAIALVSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIVPII
AIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGVKR

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI187423910, Length=422, Percent_Identity=28.9099526066351, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI7657591, Length=422, Percent_Identity=28.9099526066351, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI33286428, Length=439, Percent_Identity=28.4738041002278, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI115648063, Length=444, Percent_Identity=27.2522522522523, Blast_Score=149, Evalue=7e-36,
Organism=Homo sapiens, GI115648022, Length=444, Percent_Identity=27.2522522522523, Blast_Score=149, Evalue=7e-36,
Organism=Homo sapiens, GI186910308, Length=442, Percent_Identity=26.2443438914027, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI186910306, Length=442, Percent_Identity=26.2443438914027, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI186910304, Length=442, Percent_Identity=26.2443438914027, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI71979932, Length=445, Percent_Identity=28.5393258426966, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI7657683, Length=439, Percent_Identity=27.5626423690205, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI71999149, Length=402, Percent_Identity=27.363184079602, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI9790235, Length=438, Percent_Identity=27.3972602739726, Blast_Score=119, Evalue=8e-27,
Organism=Homo sapiens, GI258645169, Length=429, Percent_Identity=25.6410256410256, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI4507047, Length=438, Percent_Identity=26.4840182648402, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI258614003, Length=430, Percent_Identity=26.046511627907, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI258614005, Length=430, Percent_Identity=26.046511627907, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI33286430, Length=230, Percent_Identity=28.2608695652174, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI114326544, Length=425, Percent_Identity=24.9411764705882, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI114326550, Length=425, Percent_Identity=24.9411764705882, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI87082250, Length=461, Percent_Identity=27.114967462039, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI2367353, Length=438, Percent_Identity=27.3972602739726, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI87081708, Length=416, Percent_Identity=25.2403846153846, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788480, Length=463, Percent_Identity=23.3261339092873, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787890, Length=352, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786908, Length=357, Percent_Identity=22.96918767507, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87081915, Length=410, Percent_Identity=25.1219512195122, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1789017, Length=430, Percent_Identity=25.5813953488372, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790584, Length=379, Percent_Identity=24.802110817942, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786302, Length=412, Percent_Identity=23.7864077669903, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786789, Length=441, Percent_Identity=22.9024943310658, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790653, Length=427, Percent_Identity=22.0140515222482, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786602, Length=421, Percent_Identity=23.7529691211401, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71982612, Length=419, Percent_Identity=27.2076372315036, Blast_Score=137, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI71982608, Length=419, Percent_Identity=27.2076372315036, Blast_Score=137, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI32566699, Length=366, Percent_Identity=27.5956284153005, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71995388, Length=404, Percent_Identity=27.970297029703, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71995382, Length=404, Percent_Identity=27.970297029703, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI71993915, Length=405, Percent_Identity=25.679012345679, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17540018, Length=444, Percent_Identity=26.3513513513513, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI71990446, Length=469, Percent_Identity=25.7995735607676, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17568033, Length=453, Percent_Identity=25.60706401766, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71982623, Length=283, Percent_Identity=28.2685512367491, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI193208714, Length=415, Percent_Identity=23.855421686747, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32566695, Length=416, Percent_Identity=23.7980769230769, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71987339, Length=448, Percent_Identity=22.3214285714286, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=425, Percent_Identity=24.7058823529412, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321492, Length=340, Percent_Identity=22.9411764705882, Blast_Score=83, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6321751, Length=411, Percent_Identity=25.7907542579075, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24651635, Length=409, Percent_Identity=27.1393643031785, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24651633, Length=409, Percent_Identity=27.1393643031785, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI45550968, Length=445, Percent_Identity=26.5168539325843, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI19921172, Length=445, Percent_Identity=26.5168539325843, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24641995, Length=404, Percent_Identity=27.2277227722772, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24641993, Length=404, Percent_Identity=27.2277227722772, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI21357367, Length=437, Percent_Identity=26.3157894736842, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI221331183, Length=444, Percent_Identity=25.9009009009009, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17647653, Length=444, Percent_Identity=25.9009009009009, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24664379, Length=444, Percent_Identity=25.9009009009009, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24667468, Length=394, Percent_Identity=26.9035532994924, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24668806, Length=432, Percent_Identity=23.6111111111111, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356285, Length=432, Percent_Identity=23.6111111111111, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24668802, Length=432, Percent_Identity=23.6111111111111, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24666159, Length=392, Percent_Identity=24.4897959183673, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221512776, Length=392, Percent_Identity=24.4897959183673, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 46728; Mature: 46728

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRKKMGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPGLGILAWLIAGI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEEEECCCCCHHHHHHHHHHHH
ITITAGLTAAEVSVAIPKTGGMMVYIKEIYGEKLGFLTGWMQIVLFYPGMMAALGVIFGE
HHHHCCCHHHHEEEEECCCCCEEEEHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QASALIGSPSLLLPIAIGIIIIVAGLNMLGSKTGGVIQTVSTICKLIPLILIMVVGFIKG
CHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAGEMKNPGKDLPKAIIGGL
CCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHH
SVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSMGGKIISVGILISVFGALNG
HHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
FLLTGSRVAYTLATDKTLPKYGIFSKLNSAQVPANAIALVSVIASIYALSGQFNLLTDLA
EEEECCEEEEEEECCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
VFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIVPIIAIASGIFVVVNQLCFAGMKT
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMISIGGLVITAIGLPVYAYMTRGVKR
HHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRRKKMGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPGLGILAWLIAGI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEEEECCCCCHHHHHHHHHHHH
ITITAGLTAAEVSVAIPKTGGMMVYIKEIYGEKLGFLTGWMQIVLFYPGMMAALGVIFGE
HHHHCCCHHHHEEEEECCCCCEEEEHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QASALIGSPSLLLPIAIGIIIIVAGLNMLGSKTGGVIQTVSTICKLIPLILIMVVGFIKG
CHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAGEMKNPGKDLPKAIIGGL
CCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHH
SVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSMGGKIISVGILISVFGALNG
HHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
FLLTGSRVAYTLATDKTLPKYGIFSKLNSAQVPANAIALVSVIASIYALSGQFNLLTDLA
EEEECCEEEEEEECCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
VFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIVPIIAIASGIFVVVNQLCFAGMKT
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMISIGGLVITAIGLPVYAYMTRGVKR
HHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]