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The map label for this gene is rpoD1 [H]

Identifier: 126699059

GI number: 126699059

Start: 1684700

End: 1685872

Strand: Direct

Name: rpoD1 [H]

Synonym: CD1455

Alternate gene names: 126699059

Gene position: 1684700-1685872 (Clockwise)

Preceding gene: 126699058

Following gene: 126699060

Centisome position: 39.27

GC content: 33.42

Gene sequence:

>1173_bases
TTGAGTGTGGAAAATAAATCGAATAAAAAAGAGTTAAAAAAGGTTACTGCTAAGACATTAATAGAAAAAGGAAAAAAGCA
AGGTTCTCTGACACTTGCAGAGATAATGGAAGCTTTTTCGGAGACTGAACTTGATAAGGATCAAGTAGAAAATCTTTATG
AGACTTTAGGAAATTTGGGAATAGAAATAACAGAAACAAAAAACTATAAAGCTGATATAGATTTTTCGGTTGCTGATGAC
GATTTAAGTATAGGCCACTTAGATGAAGATGCAGAGGCAATTTCACATGATGACTCTTCTGCAATAGAAATAGAAACTGT
GGATTTATCTTTACCAAAAGGGATAAGTATAGATGACCCTGTAAGAATGTACTTAAAAGAAATAGGAAAAATTCCTCTAC
TTAAACCACATGAAGAAGTAGAATTTGCTAGAAGGATGCACGAAGGTGATGAGATAGCAAAACAAAGGTTAGTTGAAGCA
AACTTAAGACTAGTTGTAAGTATAGCAAAAAGATATGTAGGAAGAGGTATGCTTTTCTTGGATTTAATACAAGAGGGAAA
TTTAGGTCTTATAAAAGCAGTCGAAAAATTTGACTATACAAAAGGATATAAGTTTAGTACTTATGCAACATGGTGGATAA
GACAAGCTATAACACGTGCTATTGCAGACCAAGCTAGAACTATAAGAATACCAGTTCATATGGTAGAGACTATAAATAAG
CTAATAAGAGTATCAAGACAACTACTTCAAGAACTTGGAAGAGATCCAAAACCAGAAGAAATTGCAAAAGAAATGGAAAT
GACAGAAGATAAAGTAAGAGAAATAATGAAAATAGCTCAAGACCCTGTGTCTTTAGAAACACCAATAGGAGAAGAAGAAG
ATAGCCATTTAGGTGACTTTATTCCAGATGATGATGCTCCAGCCCCAGCAGAGGCAGCAGCATATTCTTTATTAAAAGAA
CAAATAGAAGATGTACTTGGTTCATTAAATGATAGAGAACAAAAAGTATTAAAGCTTAGATTTGGTCTTGAGGATGGTAG
AGCCAGAACTCTTGAGGAAGTTGGAAAAGAGTTTGATGTAACTAGAGAGAGAATAAGACAGATAGAAGCAAAAGCACTAA
GAAAACTAAGACATCCAAGTAGATCAAAAAAACTTAGAGATTATTTAGACTAA

Upstream 100 bases:

>100_bases
ATAATAATGATATGAAAGAGGTAGATGGTAGAGTTATGGAAATTGCTTTAAAAATAGTTGAGATAAATAAAATTTTAAAG
AGCTTGTAGAGAAAGGAGGT

Downstream 100 bases:

>100_bases
AAAGATACATCATTGATGTTTTTGTGATAAATGCCATGAGATAAGTGATATCTCATGGCTATTTTGTAGTAAAGATTTAA
TTTTATTTTTGTAGTTATTT

Product: RNA polymerase sigma factor (sigma-43)

Products: NA

Alternate protein names: Sigma-43; Sigma-A [H]

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MSVENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDKDQVENLYETLGNLGIEITETKNYKADIDFSVADD
DLSIGHLDEDAEAISHDDSSAIEIETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEA
NLRLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
LIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKIAQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKE
QIEDVLGSLNDREQKVLKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD

Sequences:

>Translated_390_residues
MSVENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDKDQVENLYETLGNLGIEITETKNYKADIDFSVADD
DLSIGHLDEDAEAISHDDSSAIEIETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEA
NLRLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
LIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKIAQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKE
QIEDVLGSLNDREQKVLKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD
>Mature_389_residues
SVENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDKDQVENLYETLGNLGIEITETKNYKADIDFSVADDD
LSIGHLDEDAEAISHDDSSAIEIETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEAN
LRLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINKL
IRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKIAQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQ
IEDVLGSLNDREQKVLKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This is the primary sigma factor of this bacterium [H]

COG id: COG0568

COG function: function code K; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family [H]

Homologues:

Organism=Escherichia coli, GI1789448, Length=250, Percent_Identity=66.8, Blast_Score=349, Evalue=2e-97,
Organism=Escherichia coli, GI1789098, Length=322, Percent_Identity=41.9254658385093, Blast_Score=248, Evalue=4e-67,
Organism=Escherichia coli, GI1789871, Length=272, Percent_Identity=29.4117647058824, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1788231, Length=199, Percent_Identity=27.1356783919598, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: 700 (log & stationary phase) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000943
- InterPro:   IPR009042
- InterPro:   IPR007627
- InterPro:   IPR007624
- InterPro:   IPR007630
- InterPro:   IPR007127
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR012760
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03979 Sigma70_r1_1; PF00140 Sigma70_r1_2; PF04542 Sigma70_r2; PF04539 Sigma70_r3; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 44427; Mature: 44296

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00715 SIGMA70_1 ; PS00716 SIGMA70_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDKDQVENLYETLGNLG
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
IEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHDDSSAIEIETVDLSLPKGISIDDP
EEEEECCCCCCCCEEEECCCCCCCCCCCHHHHHHCCCCCCEEEEEEEEEECCCCCCCCHH
VRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANLRLVVSIAKRYVGRGMLFL
HHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
DLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
HHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHH
LIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKIAQDPVSLETPIGEEEDSHLGDF
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
IPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKVLKLRFGLEDGRARTLEEVGKEFDV
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
TRERIRQIEAKALRKLRHPSRSKKLRDYLD
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure 
SVENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDKDQVENLYETLGNLG
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
IEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHDDSSAIEIETVDLSLPKGISIDDP
EEEEECCCCCCCCEEEECCCCCCCCCCCHHHHHHCCCCCCEEEEEEEEEECCCCCCCCHH
VRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANLRLVVSIAKRYVGRGMLFL
HHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
DLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
HHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHH
LIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKIAQDPVSLETPIGEEEDSHLGDF
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
IPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKVLKLRFGLEDGRARTLEEVGKEFDV
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
TRERIRQIEAKALRKLRHPSRSKKLRDYLD
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]