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The map label for this gene is yisK [H]

Identifier: 126698420

GI number: 126698420

Start: 1015654

End: 1016538

Strand: Direct

Name: yisK [H]

Synonym: CD0840

Alternate gene names: 126698420

Gene position: 1015654-1016538 (Clockwise)

Preceding gene: 126698419

Following gene: 126698421

Centisome position: 23.67

GC content: 28.47

Gene sequence:

>885_bases
ATGAAATTTGTGACTTTTTGTAGTAGCAATGAAGAAAAAATAGGTGTATTTAATTCAGAAACAAATAGTATATATGAAAT
TAATAGTTTAGGATTAAGTAAATTATATACTGATATGAATGATTTTATTGAAAACGTATCTACAGGAGATTTAGAAAAAA
TAAAAAACAATTCATTTGAAAACGCAAAGTGTTATAAGTTAGAAGAAGTTAAATTATGTTCCCCAATTGTAAGACCTAAA
AAAGATATTATATGTTTAGGTCTAAACTATAAAGACCATGTCAATGAAATCCCAGATGGAGTTATAAAAAACGTAGTTAT
GCCAGATTATCCAATTTATTTTTCTAAGAGAGCAGACAAAATAATTGGAGTGGATGATAAGATAAGCTTACATGGAGATT
TGGTAGAGAAGTTGGACTATGAATCAGAACTTGCAGTAATCATAGGTAAAGAAGGTATAAATATATCAAAAGAAGATGCT
TATGAATATATATTTGGATATACAATAGTAAATGATATAAGTGAAAGAGCACTTCAAGATAAACATGTTCAATGGTTTAG
AGGAAAAAGCTTAGACACACATACATCTATGGGACCTTGTATAGTACATAAAGAAGAATTTGAACATCCTTTAAAATTAG
ATATAAGTAGTGTAGTAAATGGAGAAGTAAGACAAGATTCTAATACAGAGTACTTTATATTTGATATACCTACTATAATA
AATGATTTATCAAGAGGAATGACTCTAAAGCCAGGAGATATAATTTCAACTGGAACTCCAGCAGGGGTTGCTATGGGGAT
GAATCCTCAAGTATATTTAAAGCATGGCGATATAGTTGAATGTAAAGTCGAAGGAATAGGAGTTTTAAAAAATATAGTTG
ATTAA

Upstream 100 bases:

>100_bases
ATATAAATATGTATTGACATATAAATATTATGAATTACAATTTATATAAACTAATAAAAATTAAATAATATTAATCAACT
TATTGAATGGAGGAATAAAA

Downstream 100 bases:

>100_bases
TGGATAAATATGCCATATAATTTTATTAGTACGAATAATTTAATTAATATAGGATTAATCAAACTTATGATTAATTTATT
ATAGAGAGGGATGAGTATAT

Product: hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIENVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPK
KDIICLGLNYKDHVNEIPDGVIKNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSVVNGEVRQDSNTEYFIFDIPTII
NDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHGDIVECKVEGIGVLKNIVD

Sequences:

>Translated_294_residues
MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIENVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPK
KDIICLGLNYKDHVNEIPDGVIKNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSVVNGEVRQDSNTEYFIFDIPTII
NDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHGDIVECKVEGIGVLKNIVD
>Mature_294_residues
MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIENVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPK
KDIICLGLNYKDHVNEIPDGVIKNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSVVNGEVRQDSNTEYFIFDIPTII
NDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHGDIVECKVEGIGVLKNIVD

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=297, Percent_Identity=34.6801346801347, Blast_Score=172, Evalue=2e-43,
Organism=Homo sapiens, GI40786394, Length=297, Percent_Identity=34.3434343434343, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI66348062, Length=210, Percent_Identity=33.8095238095238, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI215422413, Length=210, Percent_Identity=33.8095238095238, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI13654274, Length=210, Percent_Identity=33.8095238095238, Blast_Score=106, Evalue=3e-23,
Organism=Escherichia coli, GI1787428, Length=190, Percent_Identity=30, Blast_Score=86, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17557057, Length=202, Percent_Identity=33.1683168316832, Blast_Score=107, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6324161, Length=243, Percent_Identity=29.2181069958848, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI28572127, Length=295, Percent_Identity=34.5762711864407, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24663695, Length=296, Percent_Identity=32.4324324324324, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28571789, Length=214, Percent_Identity=32.7102803738318, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 33044; Mature: 33044

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIENVSTGDLEKIKNNSFE
CCEEEEECCCCCEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCC
NAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVIKNVVMPDYPIYFSKRADK
CCEEEEECHHHHHHHCCCCCCCEEEEECCCHHHHHHCCHHHHHHCCCCCCCEEEECCCCE
IIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDAYEYIFGYTIVNDISERALQD
EECCCCCEECCHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KHVQWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSVVNGEVRQDSNTEYFIFDIPTII
HHHHHHCCCCCCCCCCCCCEEEEHHHCCCCCEEEHHHHCCCCCCCCCCCEEEEEECHHHH
NDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHGDIVECKVEGIGVLKNIVD
HHHHCCCEECCCCEEECCCCCCEEECCCCEEEEECCCEEEEEECCCHHHHHHCC
>Mature Secondary Structure
MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIENVSTGDLEKIKNNSFE
CCEEEEECCCCCEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCC
NAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVIKNVVMPDYPIYFSKRADK
CCEEEEECHHHHHHHCCCCCCCEEEEECCCHHHHHHCCHHHHHHCCCCCCCEEEECCCCE
IIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDAYEYIFGYTIVNDISERALQD
EECCCCCEECCHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KHVQWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSVVNGEVRQDSNTEYFIFDIPTII
HHHHHHCCCCCCCCCCCCCEEEEHHHCCCCCEEEHHHHCCCCCCCCCCCEEEEEECHHHH
NDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHGDIVECKVEGIGVLKNIVD
HHHHCCCEECCCCEEECCCCCCEEECCCCEEEEECCCEEEEEECCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377 [H]