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The map label for this gene is act [H]

Identifier: 126698379

GI number: 126698379

Start: 970487

End: 971680

Strand: Direct

Name: act [H]

Synonym: CD0799

Alternate gene names: 126698379

Gene position: 970487-971680 (Clockwise)

Preceding gene: 126698378

Following gene: 126698380

Centisome position: 22.62

GC content: 34.09

Gene sequence:

>1194_bases
ATGAAAAAAGGAGCATTAAGCAATATAAAGGTACTTGACCTTACAAGAGTTCTTGCAGGTCCATATTGTACAATGATGTT
GGCGGATTTTGGAGCTGATGTTATAAAAATAGAGATGCCAAGAAAAGGTGATGATACAAGAGGTTTTGGACCTTTTGTAA
ATGGAGAGAGTTTATACTATGCAAATATAAATAGAAATAAAAAAGGTATCACTCTAAACCTTAAATCAGAAGAAGGAAAA
AATATATTTTTAGAAATGGTAAAACATGCTGATGTTGTAGTAGAAAATTACAGACCAGGTGTAATGGAAAAGTTAGGTCT
GGGTTATGATGAGTTGGCTAAAGTTAACAATCAAATAATTTATGGAGCTGTATCAGGATTTGGATGTTATGGACCATATT
CAGAACGTCCAGGTTATGATATTATTGCACAGGCAATGGGTGGTCTTATGAGTATAACAGGGCAAGAAGGAGGAGAACCA
ACGAGAGTTGGTAATGCTATGGGTGATGTACTAGGTGGAATGAATTTAACCATTGGTATACTCACAGCACTCAACGCTAG
AAAAATAATAGGAAAAGGACAAAGAGTAGATGTTTCCCTCGTTGATTCTGTTGTATCGTCTCTCGAAACTGGTATACAGA
GATACTTTGATTCAGGACAACCTGAACTTATGGGTAATAGATATGCTTCAGCCTATCCTTATGACTCTTTTAAGGCAAGT
GATGGAAGTTTTGTAATAGGCTGTGGTAATGACAAACTTTTTGAAAAGTTATGTAAAAAAGTTCTTTTTAGAGAAGACCT
TTTAATAGATGAGAGATTTAAAACAAATCTTAATCGTTGTGAACATTACAAGGCTCTTAAACCAGAAATAGAAAAATGGT
CTGTTAAGCATACAATAAAAGAAGCAGTTGACTTAATATCAGAGGCTGGAGTTCCTGCTGCTCCTATCTATAATCTTGAT
TGTGTTACAACAGATGAACATATAGCAAAAGCAAGAGAAATGATTGTAGATATTAGTCATCCTATTATAGGAAATATGAA
AGTCAATGGAAATCCAGTTAAGTTGATGACAACAAAAGCTAAAATTGATATGCCAGCACCATCTCTAGGGGAAAGTAACG
AGGAGATTTATAATGGTTGGCTTGGTTTTGATAGTGATAAAATAAAAGATTTAAAAGAAAATGGAGTTATTTGA

Upstream 100 bases:

>100_bases
TGCAATAACACATTTAATGAACTAATTAGAATAACTGAAAATAAATCATTAAATTTAACTTTTAATATTAATCAATATAA
TATAATTTGGAGGGAAAGTT

Downstream 100 bases:

>100_bases
TTAAAAGATAGCTAAACACACTTGTGACTTTAGTCATGGGAGGTTCAGTTAGAATAATATCAAAAAATATTAAATCAATA
CTGTAAATCAAATATAGAAT

Product: beta-alanine CoA-transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGDDTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGK
NIFLEMVKHADVVVENYRPGVMEKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDSGQPELMGNRYASAYPYDSFKAS
DGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTNLNRCEHYKALKPEIEKWSVKHTIKEAVDLISEAGVPAAPIYNLD
CVTTDEHIAKAREMIVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLKENGVI

Sequences:

>Translated_397_residues
MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGDDTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGK
NIFLEMVKHADVVVENYRPGVMEKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDSGQPELMGNRYASAYPYDSFKAS
DGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTNLNRCEHYKALKPEIEKWSVKHTIKEAVDLISEAGVPAAPIYNLD
CVTTDEHIAKAREMIVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLKENGVI
>Mature_397_residues
MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGDDTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGK
NIFLEMVKHADVVVENYRPGVMEKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDSGQPELMGNRYASAYPYDSFKAS
DGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTNLNRCEHYKALKPEIEKWSVKHTIKEAVDLISEAGVPAAPIYNLD
CVTTDEHIAKAREMIVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLKENGVI

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=395, Percent_Identity=38.2278481012658, Blast_Score=261, Evalue=7e-70,
Organism=Homo sapiens, GI300863124, Length=420, Percent_Identity=36.6666666666667, Blast_Score=252, Evalue=4e-67,
Organism=Homo sapiens, GI300863126, Length=393, Percent_Identity=34.0966921119593, Blast_Score=221, Evalue=6e-58,
Organism=Homo sapiens, GI13376042, Length=420, Percent_Identity=33.3333333333333, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI42794625, Length=401, Percent_Identity=27.1820448877805, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI266456254, Length=401, Percent_Identity=27.1820448877805, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI266458393, Length=259, Percent_Identity=32.046332046332, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI266458397, Length=259, Percent_Identity=32.046332046332, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI42822893, Length=144, Percent_Identity=35.4166666666667, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI266458395, Length=144, Percent_Identity=35.4166666666667, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI87082093, Length=378, Percent_Identity=39.6825396825397, Blast_Score=284, Evalue=6e-78,
Organism=Escherichia coli, GI1788717, Length=416, Percent_Identity=31.25, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1786222, Length=346, Percent_Identity=24.2774566473988, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32564160, Length=262, Percent_Identity=32.4427480916031, Blast_Score=117, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI115535051, Length=274, Percent_Identity=30.2919708029197, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24648431, Length=400, Percent_Identity=37.75, Blast_Score=267, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24585488, Length=266, Percent_Identity=30.4511278195489, Blast_Score=122, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 43574; Mature: 43574

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGDDTRGFGPFVNGESLYY
CCCCCCCCCCHHHHHHHHHCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEE
ANINRNKKGITLNLKSEEGKNIFLEMVKHADVVVENYRPGVMEKLGLGYDELAKVNNQII
EECCCCCCCEEEEECCCCCCHHHHHHHHHHHHEEECCCCCHHHHHCCCHHHHHHHCCEEE
YGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEPTRVGNAMGDVLGGMNLTIGI
EEECCCCCCCCCCCCCCCHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHCCCCHHHHH
LTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDSGQPELMGNRYASAYPYDSFKAS
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
DGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTNLNRCEHYKALKPEIEKWSVKHTIK
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
EAVDLISEAGVPAAPIYNLDCVTTDEHIAKAREMIVDISHPIIGNMKVNGNPVKLMTTKA
HHHHHHHHCCCCCCCEECCEEECCHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEEEE
KIDMPAPSLGESNEEIYNGWLGFDSDKIKDLKENGVI
EECCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGDDTRGFGPFVNGESLYY
CCCCCCCCCCHHHHHHHHHCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEE
ANINRNKKGITLNLKSEEGKNIFLEMVKHADVVVENYRPGVMEKLGLGYDELAKVNNQII
EECCCCCCCEEEEECCCCCCHHHHHHHHHHHHEEECCCCCHHHHHCCCHHHHHHHCCEEE
YGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEPTRVGNAMGDVLGGMNLTIGI
EEECCCCCCCCCCCCCCCHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHCCCCHHHHH
LTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDSGQPELMGNRYASAYPYDSFKAS
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
DGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTNLNRCEHYKALKPEIEKWSVKHTIK
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
EAVDLISEAGVPAAPIYNLDCVTTDEHIAKAREMIVDISHPIIGNMKVNGNPVKLMTTKA
HHHHHHHHCCCCCCCEECCEEECCHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEEEE
KIDMPAPSLGESNEEIYNGWLGFDSDKIKDLKENGVI
EECCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]