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The map label for this gene is fchA [H]

Identifier: 126698299

GI number: 126698299

Start: 881326

End: 881958

Strand: Direct

Name: fchA [H]

Synonym: CD0719

Alternate gene names: 126698299

Gene position: 881326-881958 (Clockwise)

Preceding gene: 126698298

Following gene: 126698300

Centisome position: 20.54

GC content: 32.23

Gene sequence:

>633_bases
ATGAAAATAGCAGATAAAACTTGTGTTGATTTTGTAGAAGTACTATCTTCCAAAGAAGCAGTACCAGGTGGTGGGGGAGC
TGCTGCACTAGTAGGTGCAATAGGTATGGCTTTAGGTAGTATGGTATGTAACCTTACAATAGGGAAGAAGAAGTATGCTG
AGTATGAAGAAAGTGTAAAAGAGATATTAAGTAAGGCAGGAAAGTTAGAAAAAGATTTATTAAAAATGATAGATGATGAT
GCAGAATGTTTCTTACCATTATCAAAAGCTTACGGGCTTCCTAAAGAAACAGAAGAAGAAAAAAGAATAAAAGCAGAAAC
AATGGAAAAGGCATTAAAAGTTGCTTGTGAAGTACCATTAAACATAGTAAGAGTTTGCTATGAAGCTATTAAGTTACATG
AAGATTTAGTTGATAAAGGTTCAAGACTTGCTATAAGTGATGTTGGTGTAGGAGTTCAGTGTTTAAGAGCTGCTATACTT
GGTGGACAATTAAATGTAGTTATAAATATAAATTCTATACAAGATAAAGAATATGTTAATAAGGTAAAAACAGAAGTAGA
TAAGTTAGTTGAAGATGGTGTAAAAATTTGTGATGAAGTTTATGCCAAAGTTGAAAAAGCTCTTGGAAAATAA

Upstream 100 bases:

>100_bases
ATTAATTTATAAATAAAGAGTAGGAGATATCTTAAAATAGTTCGTAAAATATCTCGAACAATTTGAGATATTTTCCTACA
TCCTTTCAAGGAGGATTATC

Downstream 100 bases:

>100_bases
TTTTTAAATGACGAAAGTAGATACTATGTTATTAATATGTGGTATATAGAATAAATTAATTTAAGTTTGCTTGTAGGGGA
GTTGTGAATGTATGGAAGGA

Product: methenyltetrahydrofolate cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCNLTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDD
AECFLPLSKAYGLPKETEEEKRIKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
GGQLNVVININSIQDKEYVNKVKTEVDKLVEDGVKICDEVYAKVEKALGK

Sequences:

>Translated_210_residues
MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCNLTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDD
AECFLPLSKAYGLPKETEEEKRIKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
GGQLNVVININSIQDKEYVNKVKTEVDKLVEDGVKICDEVYAKVEKALGK
>Mature_210_residues
MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCNLTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDD
AECFLPLSKAYGLPKETEEEKRIKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
GGQLNVVININSIQDKEYVNKVKTEVDKLVEDGVKICDEVYAKVEKALGK

Specific function: Required for both C1 and C2 metabolism [H]

COG id: COG3404

COG function: function code E; Methenyl tetrahydrofolate cyclohydrolase

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cyclodeaminase/cyclohydrolase family [H]

Homologues:

Organism=Homo sapiens, GI46255035, Length=154, Percent_Identity=25.3246753246753, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI11140815, Length=154, Percent_Identity=25.3246753246753, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007044 [H]

Pfam domain/function: PF04961 FTCD_C [H]

EC number: =3.5.4.9 [H]

Molecular weight: Translated: 22707; Mature: 22707

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCNLTIGKKKYAEYEESVK
CCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
EILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKRIKAETMEKALKVACEVPL
HHHHHHCCHHHHHHHHHCCCHHHHEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCH
NIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAILGGQLNVVININSIQDKEYVN
HHHHHHHHHHHHHHHHHCCCCEEEHHHHCHHHHHHHHHHHCCCEEEEEEECCHHHHHHHH
KVKTEVDKLVEDGVKICDEVYAKVEKALGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCNLTIGKKKYAEYEESVK
CCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
EILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKRIKAETMEKALKVACEVPL
HHHHHHCCHHHHHHHHHCCCHHHHEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCH
NIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAILGGQLNVVININSIQDKEYVN
HHHHHHHHHHHHHHHHHCCCCEEEHHHHCHHHHHHHHHHHCCCEEEEEEECCHHHHHHHH
KVKTEVDKLVEDGVKICDEVYAKVEKALGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7961516; 10215859 [H]