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The map label for this gene is ycbL [H]

Identifier: 126698221

GI number: 126698221

Start: 765815

End: 766504

Strand: Direct

Name: ycbL [H]

Synonym: CD0643

Alternate gene names: 126698221

Gene position: 765815-766504 (Clockwise)

Preceding gene: 126698220

Following gene: 126698222

Centisome position: 17.85

GC content: 29.71

Gene sequence:

>690_bases
ATGGACATCTTATTGGTTGAAGATGATAAGAATATTCGAGAAATGGTATACGATTTTCTGATTAGTGAGAATTACTCTGT
TAAAACTGCCATTGATGGAAATACAGCTATTGAAATATTTAAAAATTATTCATTTGATATTATTTTACTGGACTTGATGT
TACCAAAGTCTAGTGGTTTTGAAGTATTAAAATATATACGAAGTGTGAGTGTTGTTCCTGTTATTATTACTACTGCGAAA
GATAGTGACACAGATAAAATGCTAGGGCTTAATCTTGGTGCAGATGATTATATTACAAAGCCTTTTTCAATCGTAGAATT
GCTTGCAAGAATTAAAGCTAATATTAGACGTGCAACAGTGTACAGTAGTTCAAGAAACTCTCAAGATATGGTTATTCAGT
ATAAAGATTTGATTATAAACATATCAAAATATGTAGTTTCAAAGAGTGGAATTGCCTTGAACTTAACACATACAGAATTT
GAAATTGTTAAATTACTAGCGACTAATCAAGGACGTGCTTTTTCAAAGGAACAATTATACAACGCTATTTGGAAAGAACC
TTATTATGGAAATGAAAATGTGCTAAATACTCATATTAACAGGTTAAGAAATAAATTGTCTGATGGTATGGAAAAAAATA
ATTATATTAAAACTCTTTGGGGAATTGGCTACAAAATGGAGGAAGAATAA

Upstream 100 bases:

>100_bases
ACCAAATTGCAGATACAATATCATAAGCAGTTATTTATTGACAACCCTTTTTAATAAATATATCATTTGAAGTATACTGA
CGAAAAGGAGTTGAATAATA

Downstream 100 bases:

>100_bases
TGGAGTTATTTTTAGTTGTAATTTCTATTGTACTATTTGCTCTCTACTTAAAAGAACGAAATAAATCAAAGAAAATGGAA
AGTGATTATAAGTATATCAA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MDILLVEDDKNIREMVYDFLISENYSVKTAIDGNTAIEIFKNYSFDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAK
DSDTDKMLGLNLGADDYITKPFSIVELLARIKANIRRATVYSSSRNSQDMVIQYKDLIINISKYVVSKSGIALNLTHTEF
EIVKLLATNQGRAFSKEQLYNAIWKEPYYGNENVLNTHINRLRNKLSDGMEKNNYIKTLWGIGYKMEEE

Sequences:

>Translated_229_residues
MDILLVEDDKNIREMVYDFLISENYSVKTAIDGNTAIEIFKNYSFDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAK
DSDTDKMLGLNLGADDYITKPFSIVELLARIKANIRRATVYSSSRNSQDMVIQYKDLIINISKYVVSKSGIALNLTHTEF
EIVKLLATNQGRAFSKEQLYNAIWKEPYYGNENVLNTHINRLRNKLSDGMEKNNYIKTLWGIGYKMEEE
>Mature_229_residues
MDILLVEDDKNIREMVYDFLISENYSVKTAIDGNTAIEIFKNYSFDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAK
DSDTDKMLGLNLGADDYITKPFSIVELLARIKANIRRATVYSSSRNSQDMVIQYKDLIINISKYVVSKSGIALNLTHTEF
EIVKLLATNQGRAFSKEQLYNAIWKEPYYGNENVLNTHINRLRNKLSDGMEKNNYIKTLWGIGYKMEEE

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=34.2222222222222, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1789809, Length=224, Percent_Identity=32.1428571428571, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=36.283185840708, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=35.3982300884956, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=32.5892857142857, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=30.3571428571429, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=30.5676855895196, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1789402, Length=234, Percent_Identity=32.4786324786325, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=31.1111111111111, Blast_Score=123, Evalue=8e-30,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=30.8370044052863, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=32.15859030837, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=28.1938325991189, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=29.8245614035088, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=27.1929824561404, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=33.9622641509434, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26246; Mature: 26246

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDILLVEDDKNIREMVYDFLISENYSVKTAIDGNTAIEIFKNYSFDIILLDLMLPKSSGF
CEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCEEEEEEEECCCCCCH
EVLKYIRSVSVVPVIITTAKDSDTDKMLGLNLGADDYITKPFSIVELLARIKANIRRATV
HHHHHHHHCCEEEEEEEECCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEEE
YSSSRNSQDMVIQYKDLIINISKYVVSKSGIALNLTHTEFEIVKLLATNQGRAFSKEQLY
ECCCCCCCCEEEEEHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCCCCHHHHH
NAIWKEPYYGNENVLNTHINRLRNKLSDGMEKNNYIKTLWGIGYKMEEE
HHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEHHHCCCEEECCC
>Mature Secondary Structure
MDILLVEDDKNIREMVYDFLISENYSVKTAIDGNTAIEIFKNYSFDIILLDLMLPKSSGF
CEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCEEEEEEEECCCCCCH
EVLKYIRSVSVVPVIITTAKDSDTDKMLGLNLGADDYITKPFSIVELLARIKANIRRATV
HHHHHHHHCCEEEEEEEECCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEEE
YSSSRNSQDMVIQYKDLIINISKYVVSKSGIALNLTHTEFEIVKLLATNQGRAFSKEQLY
ECCCCCCCCEEEEEHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCCCCHHHHH
NAIWKEPYYGNENVLNTHINRLRNKLSDGMEKNNYIKTLWGIGYKMEEE
HHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]