Click here to switch to the map view.

The map label for this gene is sleB [H]

Identifier: 126698131

GI number: 126698131

Start: 658485

End: 659201

Strand: Direct

Name: sleB [H]

Synonym: CD0552

Alternate gene names: 126698131

Gene position: 658485-659201 (Clockwise)

Preceding gene: 126698129

Following gene: 126698132

Centisome position: 15.35

GC content: 27.2

Gene sequence:

>717_bases
ATGAAGCTAGATTTATTTTTATTAGCAATAATTCCTATATTGATAGGGATGTTTTGGATAAGGTCTAAAGATAGATATTG
TAGAGAACCCCTAATCCATCTAATTAAATTTTTTTTAATAGGTGCTTTTCTAAGTGTTATAATTATACTTTTAGAAAATT
TACTGATGAAGTTTAATGTATTTGAAGGGTATTCAGAACTAATATATGTATCATTTGTAGTTGCAGGACTTGTAGAAGAA
GGTGTAAAAGCTCTGATACTGATTCCTGCCCTAATTAAAGAAAAACACTTTACTGAAAAGTTAGATGGTATTATTTACTC
TGTATTTTTAGCTTTAGGATTTGCAACAATTGAAAATATGGTTTATATTTTTTCTGAAAGTAGAAATCTAGCACTGCAAG
TTGGTATTAATAGGGCAGTTATCTCTATACCAGCTCATGTAATGTTTGCAATTACTATGGGCTACTATATTTCTAAGTAT
AAATTTGAGGGAAATAAAAATAAAAGACGTGAGTATTTGTTTATGGCAGTGTTAATTCCAATTTTATTACATGGAGTTTT
TGATTTCATATTGATGATAGAATATAGATGGGCTATTATATTACTTATAGTTTATGTAATAATTTTGTGGAAGATAAATC
TTGATAAACTTGAGAAATATATGAATCACTCTAAAAAAGTGTTTTTCGGTAATCTTAGGAAAAAGAAGAAGAAATAA

Upstream 100 bases:

>100_bases
TAATGTATATTTTAGTATGTATTTAAAACACGAATAAGTTAAAAATAAGTAGATGATATAAATCATAAATAAATCAAAAA
TTTTGAAAGGAAAATAATCT

Downstream 100 bases:

>100_bases
AATTTAAAGGAAAGACATAAATAATTAAAGTATAATAAATGACACACAAGTAAAGCAGATTGAAGGGGGATTATAGATTT
GACAGAATTACCAAAGGAAT

Product: spore-cortex-lytic protein

Products: NA

Alternate protein names: Protease responsible for activating sigma-W [H]

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MKLDLFLLAIIPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFLSVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEE
GVKALILIPALIKEKHFTEKLDGIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLEKYMNHSKKVFFGNLRKKKKK

Sequences:

>Translated_238_residues
MKLDLFLLAIIPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFLSVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEE
GVKALILIPALIKEKHFTEKLDGIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLEKYMNHSKKVFFGNLRKKKKK
>Mature_238_residues
MKLDLFLLAIIPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFLSVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEE
GVKALILIPALIKEKHFTEKLDGIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLEKYMNHSKKVFFGNLRKKKKK

Specific function: Is responsible for Site-1 cleavage of the RsiW anti- sigma factor. This results, after two other proteolytic steps catalyzed by the RasP and ClpXP proteases, in the release of SigW and the transcription activation of the genes under the control of the sig

COG id: COG2339

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protease prsW family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 27827; Mature: 27827

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDLFLLAIIPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFLSVIIILLENLLMKFNV
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLDGIIYSVFLALGFATIENM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKYKFEGNKNKRREYLFMAVLIP
HHEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHH
ILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLEKYMNHSKKVFFGNLRKKKKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKLDLFLLAIIPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFLSVIIILLENLLMKFNV
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLDGIIYSVFLALGFATIENM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKYKFEGNKNKRREYLFMAVLIP
HHEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHH
ILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLEKYMNHSKKVFFGNLRKKKKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377; 8830707 [H]