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The map label for this gene is frwB [H]

Identifier: 126697779

GI number: 126697779

Start: 272045

End: 272353

Strand: Direct

Name: frwB [H]

Synonym: CD0208

Alternate gene names: 126697779

Gene position: 272045-272353 (Clockwise)

Preceding gene: 126697778

Following gene: 126697780

Centisome position: 6.34

GC content: 30.42

Gene sequence:

>309_bases
ATGAAAATTGTAGCAGTAACATCTTGTCCTAGTGGAGTAGCACATACTTACATGTCGGCTGAATCACTTGAATTATCAGC
CAAAAAATTTGGTATAGAAATAAAGGTTGAGACTCAAGGAAGCTCTGGAATAGATAATGAATTGTCACTTAAAGATATTG
ATGAAGCAACTTGTGTAATATTGACTAATGATGTTGAGATTAGAAATATGGAACGTTTTAAAGGAAAGAAGGTAGTAAGA
ATGAGTGTATCTGAGATAATTAAGAAATCTGATGCATTAATTAAGAAAATAAAAGATACTTTTCAATAA

Upstream 100 bases:

>100_bases
TGAATCAATTGAATTAATATTTGAAGAATTATAAATATAAATGGAAGGAATTTGTATAAAAAAGTAAATATAAAACTATA
AATTTAAAGGAGATAAGAAT

Downstream 100 bases:

>100_bases
AAATTGATTTATTTTACATATAACTCAAAGATGTTTTTAAAGAAATTTTTATTAAAAGCATCTTTGAAAATATCTTAAAA
ATAGAATAAAAGGAGATATA

Product: PTS system fructose-like transporter subunit EIIB

Products: NA

Alternate protein names: PTS system fructose-like EIIB component 2 [H]

Number of amino acids: Translated: 102; Mature: 102

Protein sequence:

>102_residues
MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGIDNELSLKDIDEATCVILTNDVEIRNMERFKGKKVVR
MSVSEIIKKSDALIKKIKDTFQ

Sequences:

>Translated_102_residues
MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGIDNELSLKDIDEATCVILTNDVEIRNMERFKGKKVVR
MSVSEIIKKSDALIKKIKDTFQ
>Mature_102_residues
MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGIDNELSLKDIDEATCVILTNDVEIRNMERFKGKKVVR
MSVSEIIKKSDALIKKIKDTFQ

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane [H]

COG id: COG1445

COG function: function code G; Phosphotransferase system fructose-specific component IIB

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1790387, Length=97, Percent_Identity=56.701030927835, Blast_Score=120, Evalue=2e-29,
Organism=Escherichia coli, GI87082348, Length=104, Percent_Identity=44.2307692307692, Blast_Score=92, Evalue=8e-21,
Organism=Escherichia coli, GI1786951, Length=94, Percent_Identity=42.5531914893617, Blast_Score=91, Evalue=2e-20,
Organism=Escherichia coli, GI1788730, Length=98, Percent_Identity=40.8163265306122, Blast_Score=89, Evalue=5e-20,
Organism=Escherichia coli, GI1788492, Length=89, Percent_Identity=43.8202247191011, Blast_Score=83, Evalue=4e-18,
Organism=Escherichia coli, GI1790390, Length=98, Percent_Identity=38.7755102040816, Blast_Score=74, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003353 [H]

Pfam domain/function: PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 11266; Mature: 11266

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGIDNELSLKDIDEATCVI
CEEEEEECCCCCHHHHHCCCCCCEEEHHHCCEEEEEEECCCCCCCCCCCCCCCCCEEEEE
LTNDVEIRNMERFKGKKVVRMSVSEIIKKSDALIKKIKDTFQ
EECCCCCCCHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGIDNELSLKDIDEATCVI
CEEEEEECCCCCHHHHHCCCCCCEEEHHHCCEEEEEEECCCCCCCCCCCCCCCCCEEEEE
LTNDVEIRNMERFKGKKVVRMSVSEIIKKSDALIKKIKDTFQ
EECCCCCCCHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]