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The map label for this gene is frwC [H]

Identifier: 126697778

GI number: 126697778

Start: 270923

End: 271978

Strand: Direct

Name: frwC [H]

Synonym: CD0207

Alternate gene names: 126697778

Gene position: 270923-271978 (Clockwise)

Preceding gene: 126697777

Following gene: 126697779

Centisome position: 6.31

GC content: 34.38

Gene sequence:

>1056_bases
ATGAGAATTTTAAAGTTTTTGCAAAAACATCTTATGACAGCAACATCTTATATGATTCCATTTGTGGTTGCAGGAGGAAT
ATTATTTGCTTTATCAGTAACTTTAAGTGGACAAGCTGCTGTTCCTGAAACAGGCTGGTTGGCTAAACTGAATCAAATTG
GAGCTGCTGGCTTGGCTTTATTCATTCCTATATTAGGTGGATATATAGCATTTAGTATGGCAGATAAACCAGGATTAGCT
CCAGGTATGATAGGTGCATATTTAGCAAAAGAAGTAAATGCAGGTTTTATAGGTGGTATCATAGCAGGATTTATAGCAGG
ATTTGTTGTTTTACAATTAAAGAAAATTAAATTAGCTCCTACAATGAGAACTTTAGGTTCTATATTTATTTATCCTTTAG
TTGGTACATTGATTACAGGTGGTATAATTGTATTTTTAATTGGAGAACCTATAGCTTCTTTTATGACATGGATGACAAAC
TGGTTAAATGGAATGTCTGGTGTTTCTAAAATTCCTTTAGGTGGAATCTTAGGAGGAATGATAGCCTCAGATATGGGTGG
CCCTATAAATAAGGTTGCTGCTACTTTTGCCCAAACTCAAGTTGACACACTTCCATATTTAATGGGTGGAGTTGGCGTTG
CAATTTGTATACCTCCAATTGGTTTAGGATTAGCTACATTATTGTTTCCAAAAAAATTTAGCAAGGAAGAAAGAGATTCA
GGTAAAGCTTCACTATTAATGGGATGTGTTGGAATTACAGAAGGAGCTATTCCATTTGCAACATCAGATCCAGTTAGAGT
AATACCTTGTATTATGGCTGGGTCGATTGTAGGAAATATTATGGCTTTTTTATTAGGATGTTTAAATCATGCACCCTGGG
GAGGTCTGATAGTGTTACCTGTAGTTGACAATAGGTTGGGGTATATTGCATCAGTATTAACTGGAGCAGTAGTTGTTGCG
GTATTAATGAAATTAGTAAAAAAAGACGTGAAAGAAGATGAAGAAATTGAAGAAGATTTAGATGAATCAATTGAATTAAT
ATTTGAAGAATTATAA

Upstream 100 bases:

>100_bases
CGTTTATTGATGCATGAAAGTTTTAGAAATCAAATTAGATGTTCAGATGAACAAACTGTTTATAATCTTATAAAAGAAAA
AATAGAGGAGGAAGATTAAA

Downstream 100 bases:

>100_bases
ATATAAATGGAAGGAATTTGTATAAAAAAGTAAATATAAAACTATAAATTTAAAGGAGATAAGAATATGAAAATTGTAGC
AGTAACATCTTGTCCTAGTG

Product: fructose-like permease EIIC subunit 2

Products: NA

Alternate protein names: PTS system fructose-like EIIC component 2 [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPETGWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLA
PGMIGAYLAKEVNAGFIGGIIAGFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLVGTLITGGIIVFLIGEPIASFMTWMTN
WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIPPIGLGLATLLFPKKFSKEERDS
GKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSIVGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVA
VLMKLVKKDVKEDEEIEEDLDESIELIFEEL

Sequences:

>Translated_351_residues
MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPETGWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLA
PGMIGAYLAKEVNAGFIGGIIAGFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLVGTLITGGIIVFLIGEPIASFMTWMTN
WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIPPIGLGLATLLFPKKFSKEERDS
GKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSIVGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVA
VLMKLVKKDVKEDEEIEEDLDESIELIFEEL
>Mature_351_residues
MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPETGWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLA
PGMIGAYLAKEVNAGFIGGIIAGFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLVGTLITGGIIVFLIGEPIASFMTWMTN
WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIPPIGLGLATLLFPKKFSKEERDS
GKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSIVGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVA
VLMKLVKKDVKEDEEIEEDLDESIELIFEEL

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane [H]

COG id: COG1299

COG function: function code G; Phosphotransferase system, fructose-specific IIC component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1790386, Length=313, Percent_Identity=52.7156549520767, Blast_Score=300, Evalue=9e-83,
Organism=Escherichia coli, GI1788492, Length=327, Percent_Identity=43.1192660550459, Blast_Score=244, Evalue=4e-66,
Organism=Escherichia coli, GI1786951, Length=346, Percent_Identity=32.3699421965318, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI87082348, Length=293, Percent_Identity=33.1058020477816, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1788729, Length=379, Percent_Identity=27.4406332453826, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013014
- InterPro:   IPR006327 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 36771; Mature: 36771

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPETGWLAKLNQIGAAGLAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
FIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIAGFIAGFVVLQLKKIKLAP
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TMRTLGSIFIYPLVGTLITGGIIVFLIGEPIASFMTWMTNWLNGMSGVSKIPLGGILGGM
HHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
IASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIPPIGLGLATLLFPKKFSKEERDS
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHCHHHHCC
GKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSIVGNIMAFLLGCLNHAPWGGLIVLP
CHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
VVDNRLGYIASVLTGAVVVAVLMKLVKKDVKEDEEIEEDLDESIELIFEEL
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPETGWLAKLNQIGAAGLAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
FIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIAGFIAGFVVLQLKKIKLAP
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TMRTLGSIFIYPLVGTLITGGIIVFLIGEPIASFMTWMTNWLNGMSGVSKIPLGGILGGM
HHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
IASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIPPIGLGLATLLFPKKFSKEERDS
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHCHHHHCC
GKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSIVGNIMAFLLGCLNHAPWGGLIVLP
CHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
VVDNRLGYIASVLTGAVVVAVLMKLVKKDVKEDEEIEEDLDESIELIFEEL
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7773398 [H]