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The map label for this gene is fruA [H]

Identifier: 126697777

GI number: 126697777

Start: 270469

End: 270921

Strand: Direct

Name: fruA [H]

Synonym: CD0206

Alternate gene names: 126697777

Gene position: 270469-270921 (Clockwise)

Preceding gene: 126697776

Following gene: 126697778

Centisome position: 6.3

GC content: 25.83

Gene sequence:

>453_bases
ATGAATAAATTAGTTAATGTAAAATGTTCATTTAAAATACATGTTAATTCAAAAGAAGAAGCCATTATATCGTTAGTTGA
TGTAGTGTCAAAAGAAGGATATTTAATAGATAAAAATCAATTTTTAAAAGATGTTTTAAAGAGAGAAGAAACATTGTCGA
CTTATATTGGACATGGTATAGGTCTTCCTCATAGTCAAAGTGTAGGTGTTAAAAACTCTTGTATTACAATAGGAAAGCTT
GATACTCCTATTGAATGGACAGAAGAAGGAGAAAAAGTGGATTTAATATTTTTGATATCAGTAACAAAAGACAATGAAAA
TAATCTTCATTTAAAGATTTTATCAAAATTAGCACGTTTATTGATGCATGAAAGTTTTAGAAATCAAATTAGATGTTCAG
ATGAACAAACTGTTTATAATCTTATAAAAGAAAAAATAGAGGAGGAAGATTAA

Upstream 100 bases:

>100_bases
AAATGGTTTATAAGACTAATTTTATTGCTATGTTAGAAAGTGCAAAGACAAAAGAAGAAGCAGAAGTTTTAATTCATAAA
TATGAGAAGGAGGTCACTGT

Downstream 100 bases:

>100_bases
AATGAGAATTTTAAAGTTTTTGCAAAAACATCTTATGACAGCAACATCTTATATGATTCCATTTGTGGTTGCAGGAGGAA
TATTATTTGCTTTATCAGTA

Product: PTS system transporter subunit IIA

Products: NA

Alternate protein names: EIIABC-Fru; Fructose-specific phosphotransferase enzyme IIA component; EII-Fru; PTS system fructose-specific EIIA component; Fructose-specific phosphotransferase enzyme IIB component; EIII-Fru; PTS system fructose-specific EIIB component; Fructose permease IIC component; PTS system fructose-specific EIIC component [H]

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MNKLVNVKCSFKIHVNSKEEAIISLVDVVSKEGYLIDKNQFLKDVLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKL
DTPIEWTEEGEKVDLIFLISVTKDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED

Sequences:

>Translated_150_residues
MNKLVNVKCSFKIHVNSKEEAIISLVDVVSKEGYLIDKNQFLKDVLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKL
DTPIEWTEEGEKVDLIFLISVTKDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED
>Mature_150_residues
MNKLVNVKCSFKIHVNSKEEAIISLVDVVSKEGYLIDKNQFLKDVLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKL
DTPIEWTEEGEKVDLIFLISVTKDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1762

COG function: function code GT; Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788726, Length=132, Percent_Identity=31.0606060606061, Blast_Score=78, Evalue=3e-16,
Organism=Escherichia coli, GI48994992, Length=146, Percent_Identity=27.3972602739726, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1786951, Length=119, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI2367327, Length=147, Percent_Identity=26.530612244898, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004715
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 17155; Mature: 17155

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS51094 PTS_EIIA_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLVNVKCSFKIHVNSKEEAIISLVDVVSKEGYLIDKNQFLKDVLKREETLSTYIGHGI
CCCEEEEEEEEEEEECCHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHCCC
GLPHSQSVGVKNSCITIGKLDTPIEWTEEGEKVDLIFLISVTKDNENNLHLKILSKLARL
CCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHH
LMHESFRNQIRCSDEQTVYNLIKEKIEEED
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKLVNVKCSFKIHVNSKEEAIISLVDVVSKEGYLIDKNQFLKDVLKREETLSTYIGHGI
CCCEEEEEEEEEEEECCHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHCCC
GLPHSQSVGVKNSCITIGKLDTPIEWTEEGEKVDLIFLISVTKDNENNLHLKILSKLARL
CCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHH
LMHESFRNQIRCSDEQTVYNLIKEKIEEED
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]