| Definition | Clostridium difficile 630 chromosome, complete genome. |
|---|---|
| Accession | NC_009089 |
| Length | 4,290,252 |
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The map label for this gene is licR [H]
Identifier: 126697776
GI number: 126697776
Start: 268442
End: 270472
Strand: Direct
Name: licR [H]
Synonym: CD0205
Alternate gene names: 126697776
Gene position: 268442-270472 (Clockwise)
Preceding gene: 126697775
Following gene: 126697777
Centisome position: 6.26
GC content: 26.24
Gene sequence:
>2031_bases ATGATAAGTGGGAGAATGTTACTCATCATGAATTTTCTAAAAGGAAAAAATAAGACAAGTTACAAGGATATTAGCAAACA ACTTAGTATAGAAGAAAGAAAAGTTAGATATGATATAAATAATTTAAATATTGTTTTGCGTTCATTAAACAAGTCAGTAA TACAAAAGATGAACAAAGGTGTGTTAATTATTCCTGATGACTTCCAAGTAGTATGTATAAATAATAACGAATATGTATTT TCCTTAACTGAGCGAGTATCTATTATGAAAATTATATCAATGTTTAAAATAGATAATCTAAACTTAGAAAAATTGAGTAA AGAATTTCGGGTTTCTAGAAGTTCAATTAAAAATGACCTTAATGTTTTGTCAAGTGAATTAGAAAGAAACCAAATAATTA TTACTTATGATAAATCTTTTAAAATAAGTGGAGAAGAAGACATTATATATAAGCAAAGATTGAACATATTAAAATCGTAT TCTTATCTTTTTGGTAAGGAAAAATCTGATTTAAGTGTATTTGAGAAGTATTTAGTGAATGTAATTGAAAAAATATTCAA AGGGATTTATTTGATTGATATATATAATTGGTCTATGAATTTATTATTGCAAATGGGATGGACTTTAAATGATGAATCTT TTACATGGTATGTGTCGAACATTTTCCTTTTTACATGGTATATACATTCAGATGAAAAACATCCTTTAGAATCTGCTTCA TTAAGTGAGCCGTGTTTTGAAAATAAGTTTGACCAAGAATTTGAAACAATTATTCAAAAAAAGTTGACTAAGGAACAAAT TTTTCTGTTAAAGAGTTTTGTATTTTTTACAAATAAATATGCAAGTTTAAACGAGGATATGGATTTGATTAGTACAGAAA TTATAGTTCAAGACCTAATTTACAATATGTCAGAAATATTAGAGATTAGCTTTAAAGAAGATATGATTCTTTATAAAGGA TTACTCAATCATATTGCTCCATTGATAGAGAGAATCAAGCAGAATATACAGATTTATGAGGAATTACTTCATGTAATACC AGATAAATATCAATATGTACTTGAAGCTACTAAGGTTTCTATTCAAAAAAACAGAGTTTTAAGTCAAATAAAGAATGAAA ATGAAACAATACTTTTGGCAATACATTTTTTAGGAAGTATACATAGAAATGAGAGGAATAACTACAAAAATATATTGTTA GTTTGTGGATTTGGATATGGTGTAATTGCTATGTTAAAGGATAGTTTAGTAAATGATTACCAGATAAATATAGTAGAGAG TATTCCATCATATAAGTTACAAGATTATAAAGAATGGGAAAGTATTGACTTCATTATAACAACATCAAAGATAGTAATAG ACTTGCCTAAAACAATTATTGAGATAAATCCATTTTTACAAGAAGAGGATTATTTGAAGTTTGAAGAAAAAGGGATAAAA AGAAAGAACGTCTTAACTAATTATATGTCAATAAAAAAAAGGTTGGACTTTTTAGAAGAAGATGACCAAAAAAGAGTATT AAGTATTATATGTCAAGAACTTGGATACAGTGATGAGAGAATATTATTTAGACAACTTAATTTAAGTGATTTAATAGGGA TTGATACCATAAGGATAATTGATGGAGATATGAAATGGGAAGATGCTGTAAAATTTAGTTCAAACATACTTGCTAATTGT GATTTTGTATCAGCACAATATGCTGAGAATATTATAGATATTTTAAAAAATGTGGGTTTTTATGCTGTAAAGGATAACGA ATTTGCTTTACTACATGGCAATGATAGTTCATTAGTCAAAGTAAGTTCGATAAGTTTATTAATATGTAAAGAAGCAGTTA GTTTTGGAGATAAAAAGGTTAAAATCATATTTTGCCTAGCAAGCAGAGATAAAAAAGAGCAAATTCCTGCAATAATTAAT CTAACTAAAATGGTTTATAAGACTAATTTTATTGCTATGTTAGAAAGTGCAAAGACAAAAGAAGAAGCAGAAGTTTTAAT TCATAAATATGAGAAGGAGGTCACTGTATGA
Upstream 100 bases:
>100_bases ATAGAAAGATAGTTACTGTCTTAGATAAAAACTGAAACATACATAATAATATAAAATTTGCTATATTAATAACTCTAATT ATTTTGGAAGGAGGGAAAAT
Downstream 100 bases:
>100_bases ATAAATTAGTTAATGTAAAATGTTCATTTAAAATACATGTTAATTCAAAAGAAGAAGCCATTATATCGTTAGTTGATGTA GTGTCAAAAGAAGGATATTT
Product: transcription antiterminator
Products: NA
Alternate protein names: Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]
Number of amino acids: Translated: 676; Mature: 676
Protein sequence:
>676_residues MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNIVLRSLNKSVIQKMNKGVLIIPDDFQVVCINNNEYVF SLTERVSIMKIISMFKIDNLNLEKLSKEFRVSRSSIKNDLNVLSSELERNQIIITYDKSFKISGEEDIIYKQRLNILKSY SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYVSNIFLFTWYIHSDEKHPLESAS LSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFFTNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKG LLNHIAPLIERIKQNIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENETILLAIHFLGSIHRNERNNYKNILL VCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKEWESIDFIITTSKIVIDLPKTIIEINPFLQEEDYLKFEEKGIK RKNVLTNYMSIKKRLDFLEEDDQKRVLSIICQELGYSDERILFRQLNLSDLIGIDTIRIIDGDMKWEDAVKFSSNILANC DFVSAQYAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIFCLASRDKKEQIPAIIN LTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV
Sequences:
>Translated_676_residues MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNIVLRSLNKSVIQKMNKGVLIIPDDFQVVCINNNEYVF SLTERVSIMKIISMFKIDNLNLEKLSKEFRVSRSSIKNDLNVLSSELERNQIIITYDKSFKISGEEDIIYKQRLNILKSY SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYVSNIFLFTWYIHSDEKHPLESAS LSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFFTNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKG LLNHIAPLIERIKQNIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENETILLAIHFLGSIHRNERNNYKNILL VCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKEWESIDFIITTSKIVIDLPKTIIEINPFLQEEDYLKFEEKGIK RKNVLTNYMSIKKRLDFLEEDDQKRVLSIICQELGYSDERILFRQLNLSDLIGIDTIRIIDGDMKWEDAVKFSSNILANC DFVSAQYAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIFCLASRDKKEQIPAIIN LTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV >Mature_676_residues MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNIVLRSLNKSVIQKMNKGVLIIPDDFQVVCINNNEYVF SLTERVSIMKIISMFKIDNLNLEKLSKEFRVSRSSIKNDLNVLSSELERNQIIITYDKSFKISGEEDIIYKQRLNILKSY SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYVSNIFLFTWYIHSDEKHPLESAS LSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFFTNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKG LLNHIAPLIERIKQNIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENETILLAIHFLGSIHRNERNNYKNILL VCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKEWESIDFIITTSKIVIDLPKTIIEINPFLQEEDYLKFEEKGIK RKNVLTNYMSIKKRLDFLEEDDQKRVLSIICQELGYSDERILFRQLNLSDLIGIDTIRIIDGDMKWEDAVKFSSNILANC DFVSAQYAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIFCLASRDKKEQIPAIIN LTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV
Specific function: Positive regulator of the licABCH operon [H]
COG id: COG3711
COG function: function code K; Transcriptional antiterminator
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PTS EIIB type-2 domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013196 - InterPro: IPR007737 - InterPro: IPR011608 - InterPro: IPR016152 - InterPro: IPR002178 - InterPro: IPR013011 - InterPro: IPR003501 - InterPro: IPR011991 [H]
Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF00359 PTS_EIIA_2; PF02302 PTS_IIB [H]
EC number: =2.7.1.69 [H]
Molecular weight: Translated: 79017; Mature: 79017
Theoretical pI: Translated: 5.84; Mature: 5.84
Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.0 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 1.0 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 3.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNIVLRSLNKSVIQKMNKG CCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHEEECCHHHHHHHHHHHHHHHHHCCC VLIIPDDFQVVCINNNEYVFSLTERVSIMKIISMFKIDNLNLEKLSKEFRVSRSSIKNDL EEEECCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH NVLSSELERNQIIITYDKSFKISGEEDIIYKQRLNILKSYSYLFGKEKSDLSVFEKYLVN HHHHHHHCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH VIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYVSNIFLFTWYIHSDEKHPLESAS HHHHHHCCEEEEEEECCCHHHHHEECCEECCCCEEEEEEEEEEEEEEEECCCCCCCCCCC LSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFFTNKYASLNEDMDLISTEIIVQDLI CCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH YNMSEILEISFKEDMILYKGLLNHIAPLIERIKQNIQIYEELLHVIPDKYQYVLEATKVS HCHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH IQKNRVLSQIKNENETILLAIHFLGSIHRNERNNYKNILLVCGFGYGVIAMLKDSLVNDY HHHHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHCCCE QINIVESIPSYKLQDYKEWESIDFIITTSKIVIDLPKTIIEINPFLQEEDYLKFEEKGIK EEEEECCCCCCCCCCCCCCCCEEEEEEECEEEEECCHHHHCCCCCCCCCCCHHHHHCCCC RKNVLTNYMSIKKRLDFLEEDDQKRVLSIICQELGYSDERILFRQLNLSDLIGIDTIRII HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHEEECCHHHHCCCCEEEEE DGDMKWEDAVKFSSNILANCDFVSAQYAENIIDILKNVGFYAVKDNEFALLHGNDSSLVK ECCCCHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCEEE VSSISLLICKEAVSFGDKKVKIIFCLASRDKKEQIPAIINLTKMVYKTNFIAMLESAKTK EECHHHEEEHHHHHCCCCEEEEEEEECCCCCCHHCHHHHHHHHHHHHHHHHHHHHHCCCH EEAEVLIHKYEKEVTV HHHHHHHHHHHHHCCC >Mature Secondary Structure MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNIVLRSLNKSVIQKMNKG CCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHEEECCHHHHHHHHHHHHHHHHHCCC VLIIPDDFQVVCINNNEYVFSLTERVSIMKIISMFKIDNLNLEKLSKEFRVSRSSIKNDL EEEECCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH NVLSSELERNQIIITYDKSFKISGEEDIIYKQRLNILKSYSYLFGKEKSDLSVFEKYLVN HHHHHHHCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH VIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYVSNIFLFTWYIHSDEKHPLESAS HHHHHHCCEEEEEEECCCHHHHHEECCEECCCCEEEEEEEEEEEEEEEECCCCCCCCCCC LSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFFTNKYASLNEDMDLISTEIIVQDLI CCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH YNMSEILEISFKEDMILYKGLLNHIAPLIERIKQNIQIYEELLHVIPDKYQYVLEATKVS HCHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH IQKNRVLSQIKNENETILLAIHFLGSIHRNERNNYKNILLVCGFGYGVIAMLKDSLVNDY HHHHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHCCCE QINIVESIPSYKLQDYKEWESIDFIITTSKIVIDLPKTIIEINPFLQEEDYLKFEEKGIK EEEEECCCCCCCCCCCCCCCCEEEEEEECEEEEECCHHHHCCCCCCCCCCCHHHHHCCCC RKNVLTNYMSIKKRLDFLEEDDQKRVLSIICQELGYSDERILFRQLNLSDLIGIDTIRII HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHEEECCHHHHCCCCEEEEE DGDMKWEDAVKFSSNILANCDFVSAQYAENIIDILKNVGFYAVKDNEFALLHGNDSSLVK ECCCCHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCEEE VSSISLLICKEAVSFGDKKVKIIFCLASRDKKEQIPAIINLTKMVYKTNFIAMLESAKTK EECHHHEEEHHHHHCCCCEEEEEEEECCCCCCHHCHHHHHHHHHHHHHHHHHHHHHCCCH EEAEVLIHKYEKEVTV HHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8990303; 8969509; 9384377; 10438772 [H]