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The map label for this gene is gmr [H]

Identifier: 126697775

GI number: 126697775

Start: 265952

End: 268186

Strand: Direct

Name: gmr [H]

Synonym: CD0204

Alternate gene names: 126697775

Gene position: 265952-268186 (Clockwise)

Preceding gene: 126697772

Following gene: 126697776

Centisome position: 6.2

GC content: 26.31

Gene sequence:

>2235_bases
ATGAAATTATCAAGGTATAAGAAAAATAGTTTAGTTCTGTCTATAATTTTATGTTCACTTATTATTTCAATCCTTGTAAT
TACTGTTTTTAATACCGTAAAACTACACAATATATCTAATAAACAATCTAAAAACTATTTAAACGATGTATCTACACAGA
TTGTAATGAATGTTGATTCTAAAATCAAATTTATTTTATCCGACTTAAGAATAATGGCAGATTTTATTAAGCAATATGAA
GGTGATAGTCGATATGAGTATTTATCTAAAAGAAAGACTAGTTATAAGTATTATGATGTTGGAATAATAGATTTAAAAGG
TAAAGCTGAGTTTTTAAGTGGAAAAAAGTTTGACTTAAAGAATACTGCTTCCTATAAAAAAGGAATTGAAGGTAAAGAAT
ACTCAGAAGTAATAGAGTCAATGGGTTTTGTTCTTTATAGTGTACCTATATTTAATGATAATCATGAAGTATCTAGTATT
TTAATAGGTGTATCTGATAAAGAAAGTATGAATGAGATTCTTAATATAGATAACTTTAATGGAAAAGGAACTATTGAAAT
TATTAATAGTAAGGGAAAACCTCTTTTCATAGGAAAAAATACTGAATTAATAAAGGACCTTAGCCATAAATATAAGAGTT
CTGGAGATGAACCTTGGGCACAAAAGATGCTTGAGGATTTTAAAAATGATAAATCAGGGAATATTACAATAACCTCATCA
AAAGGTGTACAATGCTTATTAACTTATCATCCAATTACAAGAGGTTTAAATGATTGGCATTTTCTTCTCATAGTACCTGA
AGATGCTGTACTTGGTGAACTTAATAAATTAAACTCTTTTACAATAACAATGACATTTATAATCACATGTATTATTGGAA
TTATAACATTAATTTTATATATTATAAGAAGAAAATATGTAAATCAAATAGAAAATATTGCATATTTAGATAGTATAACA
AATGGTATAAACTCAACTAAGTTTAGTATGCTAGTCAAACCTTTAATTTCAGAATCACCTGATAGTACTTATATGATGAT
AGCAATGAATATAAAAGATTTTAAGCTAATAAATGATTGTTTCGGTAGTGAAAAGGGAAATATGACACTAAAACATCTTT
ACAATATTTTGTATAAAAACATTGATGAAAATGAAGAGTTTGTGTGCCGTCATGATGCAGACCTTTTCTATTTGCTTATT
AAGAATAGACCAGTGTTAGAAGCCCTGGAGTTATTATATAAAATAGAAGCTGACACAAATTATTTTAATAAAAATAGGGA
AAATCCATACTTTTTAAGACTATCAGTAGGTATTTACACAATTGAAAATCATAATGAAGATTTAATTACAATACAAGACC
ATGCAAATACAGCAAGAAAAAGCTTTAATAAAACTCATCAAAGTGATTTTTCTTTTTATAGTGATATAGAAAGAAAACGA
TTAATATCTGAAAAGGAAATTTCAAATTTAATGGAAAAAGCCCTTGAAAATAAAGAATTTTTTATGTGCTTACAACCCAA
AATTGATATAAAAAGTGGAAAAATTAGTGGAGCAGAGTCTCTTGTGCGTTGGAAAAATTCAGAAAAGGGCATAATTTATC
CAAGTGATTTTATTCCTCTTTTCGAAAAAAGTGGATTTATATGTAAGTTAGATTTATATATACTAGAAGAAACATGCAAA
TTGATTTCTAAGTGGATAAAAGAAGGTAAAGAAGTGTTGAGAATTTCTGTTAATGTATCACGTCAACATCTGAATGATAA
ATTGTTTTTAGAAAAATATAAGCATATATGCAATAAATACAATGTACCAACATGTCTGATAGATTTAGAACTTACCGAAT
CTATTTTCTTAGAAAATCCAGAAGCTATAGATATAATAGAGGATATTCATTCTAATGGATTTAAGTGTTCTATAGACGAT
TTTGGATTTGGGTACTCATCATTAGGAATATTAAAGGATTTTAAAGTTGATATAATTAAGTTAGACCGTTCATTCTTTGT
TAGCAAAAATAATATAGACCGTGGTAAGGTAGTTATTAAGTCTATTATTGAACTTAGCAAAAGGCTAGGTATGAAAGTAA
CAGCTGAAGGAATTGAAGAATTAGAACAAGTTGAGTTTCTAAAAAATGTGGGATGTGATTATATTCAAGGTTATGTTTTT
TCAAAACCATTATTAATTTCTGACTTTGAAAATTTTGCATATGAAAATAATAAAATTAAAAATATCCATTATTAA

Upstream 100 bases:

>100_bases
AGAAATAGAATACTATAATATAGTGTGAAGGATTTTTAGTAAAAAAATTTGTAAGTGTTAATATACATTAAAAAATAGGT
TTATAATTTGGAGGAAAAAA

Downstream 100 bases:

>100_bases
ATGTACAAGATAAAAAATTTAGGCAAGTTATATAATTAAAAATATAACTTGTCTTTTTTATTTATATATTTAATAAAAAT
ATATTTGCAGATTTTGTAAA

Product: signaling protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 744; Mature: 744

Protein sequence:

>744_residues
MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSKNYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYE
GDSRYEYLSKRKTSYKYYDVGIIDLKGKAEFLSGKKFDLKNTASYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSI
LIGVSDKESMNEILNIDNFNGKGTIEIINSKGKPLFIGKNTELIKDLSHKYKSSGDEPWAQKMLEDFKNDKSGNITITSS
KGVQCLLTYHPITRGLNDWHFLLIVPEDAVLGELNKLNSFTITMTFIITCIIGIITLILYIIRRKYVNQIENIAYLDSIT
NGINSTKFSMLVKPLISESPDSTYMMIAMNIKDFKLINDCFGSEKGNMTLKHLYNILYKNIDENEEFVCRHDADLFYLLI
KNRPVLEALELLYKIEADTNYFNKNRENPYFLRLSVGIYTIENHNEDLITIQDHANTARKSFNKTHQSDFSFYSDIERKR
LISEKEISNLMEKALENKEFFMCLQPKIDIKSGKISGAESLVRWKNSEKGIIYPSDFIPLFEKSGFICKLDLYILEETCK
LISKWIKEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENPEAIDIIEDIHSNGFKCSIDD
FGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSIIELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVF
SKPLLISDFENFAYENNKIKNIHY

Sequences:

>Translated_744_residues
MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSKNYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYE
GDSRYEYLSKRKTSYKYYDVGIIDLKGKAEFLSGKKFDLKNTASYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSI
LIGVSDKESMNEILNIDNFNGKGTIEIINSKGKPLFIGKNTELIKDLSHKYKSSGDEPWAQKMLEDFKNDKSGNITITSS
KGVQCLLTYHPITRGLNDWHFLLIVPEDAVLGELNKLNSFTITMTFIITCIIGIITLILYIIRRKYVNQIENIAYLDSIT
NGINSTKFSMLVKPLISESPDSTYMMIAMNIKDFKLINDCFGSEKGNMTLKHLYNILYKNIDENEEFVCRHDADLFYLLI
KNRPVLEALELLYKIEADTNYFNKNRENPYFLRLSVGIYTIENHNEDLITIQDHANTARKSFNKTHQSDFSFYSDIERKR
LISEKEISNLMEKALENKEFFMCLQPKIDIKSGKISGAESLVRWKNSEKGIIYPSDFIPLFEKSGFICKLDLYILEETCK
LISKWIKEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENPEAIDIIEDIHSNGFKCSIDD
FGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSIIELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVF
SKPLLISDFENFAYENNKIKNIHY
>Mature_744_residues
MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSKNYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYE
GDSRYEYLSKRKTSYKYYDVGIIDLKGKAEFLSGKKFDLKNTASYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSI
LIGVSDKESMNEILNIDNFNGKGTIEIINSKGKPLFIGKNTELIKDLSHKYKSSGDEPWAQKMLEDFKNDKSGNITITSS
KGVQCLLTYHPITRGLNDWHFLLIVPEDAVLGELNKLNSFTITMTFIITCIIGIITLILYIIRRKYVNQIENIAYLDSIT
NGINSTKFSMLVKPLISESPDSTYMMIAMNIKDFKLINDCFGSEKGNMTLKHLYNILYKNIDENEEFVCRHDADLFYLLI
KNRPVLEALELLYKIEADTNYFNKNRENPYFLRLSVGIYTIENHNEDLITIQDHANTARKSFNKTHQSDFSFYSDIERKR
LISEKEISNLMEKALENKEFFMCLQPKIDIKSGKISGAESLVRWKNSEKGIIYPSDFIPLFEKSGFICKLDLYILEETCK
LISKWIKEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENPEAIDIIEDIHSNGFKCSIDD
FGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSIIELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVF
SKPLLISDFENFAYENNKIKNIHY

Specific function: Part of a 2 protein system that seems to be dedicated to transcription of csgD. This protein decreases csgD transcription and thus decreases expression of adhesive curli fimbriae genes csgEFG, csgBAC/ymaD and adrA (yaic). Activity of this protein is antag

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=440, Percent_Identity=29.3181818181818, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1790496, Length=234, Percent_Identity=34.1880341880342, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI87081743, Length=246, Percent_Identity=34.5528455284553, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI87081921, Length=440, Percent_Identity=24.5454545454545, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI226510982, Length=294, Percent_Identity=29.5918367346939, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI1786507, Length=279, Percent_Identity=30.8243727598566, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788502, Length=240, Percent_Identity=32.0833333333333, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI87081845, Length=252, Percent_Identity=30.1587301587302, Blast_Score=136, Evalue=6e-33,
Organism=Escherichia coli, GI87081980, Length=244, Percent_Identity=29.9180327868852, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1787055, Length=266, Percent_Identity=29.6992481203008, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1788849, Length=249, Percent_Identity=28.5140562248996, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI87082096, Length=246, Percent_Identity=29.2682926829268, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF00989 PAS [H]

EC number: =3.1.4.52 [H]

Molecular weight: Translated: 85804; Mature: 85804

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSKNYLNDVSTQIVMNVDS
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCEEEEECCH
KIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDVGIIDLKGKAEFLSGKKFDLK
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEEEEEECCCHHHHCCCCCCCC
NTASYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSILIGVSDKESMNEILNIDNFN
CCHHHHCCCCCCHHHHHHHHCCEEEEEEEEECCCCCEEEEEEECCCHHHHHHHHCCCCCC
GKGTIEIINSKGKPLFIGKNTELIKDLSHKYKSSGDEPWAQKMLEDFKNDKSGNITITSS
CCEEEEEEECCCCEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEEC
KGVQCLLTYHPITRGLNDWHFLLIVPEDAVLGELNKLNSFTITMTFIITCIIGIITLILY
CCCEEEEEECHHHCCCCCEEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
IIRRKYVNQIENIAYLDSITNGINSTKFSMLVKPLISESPDSTYMMIAMNIKDFKLINDC
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHH
FGSEKGNMTLKHLYNILYKNIDENEEFVCRHDADLFYLLIKNRPVLEALELLYKIEADTN
HCCCCCCEEHHHHHHHHHHCCCCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHCCCCC
YFNKNRENPYFLRLSVGIYTIENHNEDLITIQDHANTARKSFNKTHQSDFSFYSDIERKR
HHCCCCCCCEEEEEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHCHHHHHHHHHHH
LISEKEISNLMEKALENKEFFMCLQPKIDIKSGKISGAESLVRWKNSEKGIIYPSDFIPL
HHHHHHHHHHHHHHHCCCCEEEEECCCEECCCCCCCCHHHHHHHCCCCCCEECCCCCCHH
FEKSGFICKLDLYILEETCKLISKWIKEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKY
HCCCCCEEEEHHHHHHHHHHHHHHHHHCCHHEEEEEEEEHHHHCCHHHHHHHHHHHHCCC
NVPTCLIDLELTESIFLENPEAIDIIEDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIK
CCCEEEEEEEEHHHHHCCCCCHHHHHHHHCCCCCEEEECCCCCCHHHHCHHHHCCEEEEE
LDRSFFVSKNNIDRGKVVIKSIIELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVF
ECHHHEEECCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCHHHHHHHHH
SKPLLISDFENFAYENNKIKNIHY
CCCEEEECHHHHHCCCCCEECCCC
>Mature Secondary Structure
MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSKNYLNDVSTQIVMNVDS
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCEEEEECCH
KIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDVGIIDLKGKAEFLSGKKFDLK
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEEEEEECCCHHHHCCCCCCCC
NTASYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSILIGVSDKESMNEILNIDNFN
CCHHHHCCCCCCHHHHHHHHCCEEEEEEEEECCCCCEEEEEEECCCHHHHHHHHCCCCCC
GKGTIEIINSKGKPLFIGKNTELIKDLSHKYKSSGDEPWAQKMLEDFKNDKSGNITITSS
CCEEEEEEECCCCEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEEC
KGVQCLLTYHPITRGLNDWHFLLIVPEDAVLGELNKLNSFTITMTFIITCIIGIITLILY
CCCEEEEEECHHHCCCCCEEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
IIRRKYVNQIENIAYLDSITNGINSTKFSMLVKPLISESPDSTYMMIAMNIKDFKLINDC
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHH
FGSEKGNMTLKHLYNILYKNIDENEEFVCRHDADLFYLLIKNRPVLEALELLYKIEADTN
HCCCCCCEEHHHHHHHHHHCCCCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHCCCCC
YFNKNRENPYFLRLSVGIYTIENHNEDLITIQDHANTARKSFNKTHQSDFSFYSDIERKR
HHCCCCCCCEEEEEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHCHHHHHHHHHHH
LISEKEISNLMEKALENKEFFMCLQPKIDIKSGKISGAESLVRWKNSEKGIIYPSDFIPL
HHHHHHHHHHHHHHHCCCCEEEEECCCEECCCCCCCCHHHHHHHCCCCCCEECCCCCCHH
FEKSGFICKLDLYILEETCKLISKWIKEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKY
HCCCCCEEEEHHHHHHHHHHHHHHHHHCCHHEEEEEEEEHHHHCCHHHHHHHHHHHHCCC
NVPTCLIDLELTESIFLENPEAIDIIEDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIK
CCCEEEEEEEEHHHHHCCCCCHHHHHHHHCCCCCEEEECCCCCCHHHHCHHHHCCEEEEE
LDRSFFVSKNNIDRGKVVIKSIIELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVF
ECHHHEEECCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCHHHHHHHHH
SKPLLISDFENFAYENNKIKNIHY
CCCEEEECHHHHHCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]