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The map label for this gene is comF [H]

Identifier: 126697705

GI number: 126697705

Start: 179479

End: 180261

Strand: Direct

Name: comF [H]

Synonym: CD0133

Alternate gene names: 126697705

Gene position: 179479-180261 (Clockwise)

Preceding gene: 126697704

Following gene: 126697706

Centisome position: 4.18

GC content: 21.33

Gene sequence:

>783_bases
ATGAAAATATGCAATGATAATTTTATTAAGAATTTTAAAAATATGATTAATAAATGTTTGGATTTTATATATCCTGAGAA
TATAAGTTGCATAATTTGTGATAAATCCATAAAGAAAACAAATACTTATTCAATATTTAAAAGTTGTTTTAAAGAAATGA
ATTTTATACAAGATGGTTGCATGAAGTGTGGAAAACCAATAATACGTCATTCAATTGAAAAAGAATTTATTGAAGAGTGT
AGTTATTGTTTTAATAAAGACTTTTATTTTGATAAATCAATATCTTGTATTGAATACAATGATGTGACAAAAAAGATGGT
GTTAGGGCTGAAGTATAACCAAAAAACCTTTATGGCTAAGTATATAGCTCAAATAATGAAAGAAAAATTATATTTAGAAA
ACATAAAATTTGATTATATATTATTTGTTCCACTTCATAAAAAAAGGCTAAATAAAAGAGGTTTTAATCAGGCACAAAAA
ATAGCATTTAATTTAAGTAAAATAGTAAATATTCCATTATTAGATTGCATAAGTAGAAAAAAATATACAAGAATGCTATA
TAAATTGAATAAGAAAGAACGAAAAGAAGAATTAAAAAATGTATTTGTTGTTAAAGAAAATGTTAAATTAATAAATAATA
AAAATATACTTTTAATAGATGATATATTTACTACTGGTCTAACAACAAACGAAATTTCTAAACTTTTAAAGTTATCAGGT
GCTAATAAGGTTTTTGTATTGACTCTACTTACAAAAGCAAATGATAATTATATTATGGAATAA

Upstream 100 bases:

>100_bases
TTGAATATATGATAAAAAATAATAGAGTTAATCAAAGGTATTCAAATTTAGGATATAAGCTAAATAAATTTAAACAAGAA
GGGTTGTTGATAGAATAAAT

Downstream 100 bases:

>100_bases
TCTTATATATTGACAATTTTAGTTTAAAATATTAAAATGAATAAGTGATATTTAGGTCTGTGGTTGAAAGTCCAAGCCAG
TCGCAGGCAAAGGGATCCAC

Product: phosphoribosyl transferase

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MKICNDNFIKNFKNMINKCLDFIYPENISCIICDKSIKKTNTYSIFKSCFKEMNFIQDGCMKCGKPIIRHSIEKEFIEEC
SYCFNKDFYFDKSISCIEYNDVTKKMVLGLKYNQKTFMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQK
IAFNLSKIVNIPLLDCISRKKYTRMLYKLNKKERKEELKNVFVVKENVKLINNKNILLIDDIFTTGLTTNEISKLLKLSG
ANKVFVLTLLTKANDNYIME

Sequences:

>Translated_260_residues
MKICNDNFIKNFKNMINKCLDFIYPENISCIICDKSIKKTNTYSIFKSCFKEMNFIQDGCMKCGKPIIRHSIEKEFIEEC
SYCFNKDFYFDKSISCIEYNDVTKKMVLGLKYNQKTFMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQK
IAFNLSKIVNIPLLDCISRKKYTRMLYKLNKKERKEELKNVFVVKENVKLINNKNILLIDDIFTTGLTTNEISKLLKLSG
ANKVFVLTLLTKANDNYIME
>Mature_260_residues
MKICNDNFIKNFKNMINKCLDFIYPENISCIICDKSIKKTNTYSIFKSCFKEMNFIQDGCMKCGKPIIRHSIEKEFIEEC
SYCFNKDFYFDKSISCIEYNDVTKKMVLGLKYNQKTFMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQK
IAFNLSKIVNIPLLDCISRKKYTRMLYKLNKKERKEELKNVFVVKENVKLINNKNILLIDDIFTTGLTTNEISKLLKLSG
ANKVFVLTLLTKANDNYIME

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

Organism=Escherichia coli, GI87082263, Length=226, Percent_Identity=23.0088495575221, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 30749; Mature: 30749

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKICNDNFIKNFKNMINKCLDFIYPENISCIICDKSIKKTNTYSIFKSCFKEMNFIQDGC
CCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
MKCGKPIIRHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDVTKKMVLGLKYNQKTFMAK
HHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHCCCCCHHHHHHH
YIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQKIAFNLSKIVNIPLLDCISRK
HHHHHHHHHHHHHCCCEEEEEEEECHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHH
KYTRMLYKLNKKERKEELKNVFVVKENVKLINNKNILLIDDIFTTGLTTNEISKLLKLSG
HHHHHHHHHHHHHHHHHHHHEEEEECCEEEECCCCEEEEECHHHCCCCHHHHHHHHHHCC
ANKVFVLTLLTKANDNYIME
CCEEEEEEEEEECCCCCCCC
>Mature Secondary Structure
MKICNDNFIKNFKNMINKCLDFIYPENISCIICDKSIKKTNTYSIFKSCFKEMNFIQDGC
CCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
MKCGKPIIRHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDVTKKMVLGLKYNQKTFMAK
HHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHCCCCCHHHHHHH
YIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQKIAFNLSKIVNIPLLDCISRK
HHHHHHHHHHHHHCCCEEEEEEEECHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHH
KYTRMLYKLNKKERKEELKNVFVVKENVKLINNKNILLIDDIFTTGLTTNEISKLLKLSG
HHHHHHHHHHHHHHHHHHHHEEEEECCEEEECCCCEEEEECHHHCCCCHHHHHHHHHHCC
ANKVFVLTLLTKANDNYIME
CCEEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]