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The map label for this gene is manR [H]

Identifier: 126697706

GI number: 126697706

Start: 180593

End: 182506

Strand: Direct

Name: manR [H]

Synonym: CD0134

Alternate gene names: 126697706

Gene position: 180593-182506 (Clockwise)

Preceding gene: 126697705

Following gene: 126697707

Centisome position: 4.21

GC content: 23.62

Gene sequence:

>1914_bases
GTGATATGTTTGAATAAAAGACAAGAAAATTTATTAACAACATTGCTATTAAAAGAAGAGTTTATAAATGTTAATAAGAT
TGCCAATGATTTTGAGTGTTCAGAAAGGACAATAAGAAATGATTGCAAATATATTGATGAATGGTTATCTACTTTTTGTA
ATGCTTATATCAAAAGAAAACCTAATATTGGGATTAAATTTAGTGGAGATGGAACAGACAAAATACTGGTAAATCAGAAG
TTGCGAGGTGAAGTTAAAAGAGTAAATAGTGAGCTTCATAAGCAAGTTGAGATATTAAATTTACTACTTTGTAATAATAA
AAAAGTTACTTTAAATGATTTATCTAATAAGTTGTACATAAATAAAAATATTGTCAGAGAAGAAATAAGTAAATTATCAG
TAGCATTAAATAATTATAATTTAAATATCTCGACTAAAAAAGGCAGTGGTATATATATTGAAGGGGATGAGAAAGACATA
AGAATAATGTTAGTATCATTCTTATTTAAATACATAGATAAATACAGATTAAACATAGATGAAATAGAGTACTTCCATAT
AGTAGATATAATAATTGTAAAAAACATAATGCTTACTATAGAGGAGGATATGGATATAAGACTTACAGATATATCATTCA
AGCAATTGATGCTATTTTTGCTTATAAATATAATACGAATAAGGCTGGGAAATTCTTTAAAAGTATCAAATACTAAGAAA
GAGCTTAAGCTAAAAATGCTTATATTGGATATAGAAGATGAATTGAAATCTAATTTATCCATAGTATTAAATTATGAAGA
AAAATTGTTTATAGAATCTTTAATATTGGGTATGAACAAACAAATAAATAGTAATAATATTAAGAAATCTTTATATCTAA
ATGAAGAATTAGCAAGTTATACAAAAAAAATTATAAATTTAGTATCAGAAGAATCAGGAATAAATTTTAATAATGATATA
TTACTTTATGAACAATTAATATGTCATTTGAATGTTACAATGCATCAAATGAAAAGCAATGTTTACTTAGAAAATCCACT
TTTAGATAACATAAAAACTAAATTTTGTTTTTTATTTACAGTAATATCAAGTTCAATAGAAATTGAATTAAAAGGAAAAC
AAATAACGGAAGGTGAAATTGGTTATCTTACACTTCACTTTCAAACCTCTCTAGAAAGAAAATACAGCAAAAGGGAATCA
AATAAAAAGGCAAGTATTGTATGTCCATTTAGTTTTGGAGTAAGTATGCTATTAAAAGTAAAGATAGAAAAGAGATTTGA
TAACATAAAAATTATTGAAACATTAAGAGAGGAAGATTTAAAAAGAGATAACTTTAATAAGACTATAGATTTTATAATTG
CATTTCAAGAGTATGAAAATATCCAAAAACCAATTTTTATAACAACACCATTATTTACTGATGAGGATGAGAATAAACTT
AAAGAGTTCACAAACAAAATAAAAGAAAAAGACACTTCATATAAACTTATGAACAGATTAATGATGTCTGATTATTTAAT
AAGAGAGTTAGAACATGATGATATTTATGAAGCTATAACATATTTAACTAATTTATTAATTGAAAAACATTATGCAGAAA
AAGAGTATTTACAATCTATTATAACAAGAGAAAAGTCATATCCAACCAATGTTGGAAAAGGAATATTATTCCCTCATGGA
GACATGAAATATATAAAACAATCTGTTTTATGTTTTGCAAGGTTAAAAACACCAATAAAAATTAGAAATGGAAAGGATAT
AAAGATTATACTTTTGTTAGCATATAAAAAAGATGATGATAGAAAAGTATTTAGAGAATTATTTAAAGAAATATCTAATT
TAACAGAGGATGAAAATATGCTAGATATTCTAAGTAAATGTGACATTGAAAAGGTAAAAGATATTCTTATATAA

Upstream 100 bases:

>100_bases
AAAAACCAGGTCAGCTAAATATCATATTAAAAGAGAGCTAGCATACCTTTATGTATAGCTCTTTTTTATATATAATAAAT
TTAGGTTGAGTCATAAAGAG

Downstream 100 bases:

>100_bases
AATTCATAGTGAACTATGGATAAGCACAAAATTTTCCATGTGATGGAAAAAGTTGTGCATGTTTTTTTGTTTTTATAAGA
TATTATATGTTTGTAAGGTA

Product: transcription antiterminator

Products: NA

Alternate protein names: Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 637; Mature: 637

Protein sequence:

>637_residues
MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKYIDEWLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQK
LRGEVKRVNSELHKQVEILNLLLCNNKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNISTKKGSGIYIEGDEKDI
RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMLTIEEDMDIRLTDISFKQLMLFLLINIIRIRLGNSLKVSNTKK
ELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLILGMNKQINSNNIKKSLYLNEELASYTKKIINLVSEESGINFNNDI
LLYEQLICHLNVTMHQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEGEIGYLTLHFQTSLERKYSKRES
NKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTIDFIIAFQEYENIQKPIFITTPLFTDEDENKL
KEFTNKIKEKDTSYKLMNRLMMSDYLIRELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHG
DMKYIKQSVLCFARLKTPIKIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDILSKCDIEKVKDILI

Sequences:

>Translated_637_residues
MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKYIDEWLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQK
LRGEVKRVNSELHKQVEILNLLLCNNKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNISTKKGSGIYIEGDEKDI
RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMLTIEEDMDIRLTDISFKQLMLFLLINIIRIRLGNSLKVSNTKK
ELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLILGMNKQINSNNIKKSLYLNEELASYTKKIINLVSEESGINFNNDI
LLYEQLICHLNVTMHQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEGEIGYLTLHFQTSLERKYSKRES
NKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTIDFIIAFQEYENIQKPIFITTPLFTDEDENKL
KEFTNKIKEKDTSYKLMNRLMMSDYLIRELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHG
DMKYIKQSVLCFARLKTPIKIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDILSKCDIEKVKDILI
>Mature_637_residues
MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKYIDEWLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQK
LRGEVKRVNSELHKQVEILNLLLCNNKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNISTKKGSGIYIEGDEKDI
RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMLTIEEDMDIRLTDISFKQLMLFLLINIIRIRLGNSLKVSNTKK
ELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLILGMNKQINSNNIKKSLYLNEELASYTKKIINLVSEESGINFNNDI
LLYEQLICHLNVTMHQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEGEIGYLTLHFQTSLERKYSKRES
NKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTIDFIIAFQEYENIQKPIFITTPLFTDEDENKL
KEFTNKIKEKDTSYKLMNRLMMSDYLIRELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHG
DMKYIKQSVLCFARLKTPIKIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDILSKCDIEKVKDILI

Specific function: May regulate the expression of the mannose operon [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR007737
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF00359 PTS_EIIA_2 [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 74862; Mature: 74862

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKYIDEWLSTFCNAYIKRK
CCCCCCHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLLLCNNKKVTLNDLSNKLYI
CCCCEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCEEEE
NKNIVREEISKLSVALNNYNLNISTKKGSGIYIEGDEKDIRIMLVSFLFKYIDKYRLNID
CHHHHHHHHHHHHEEEECEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCHH
EIEYFHIVDIIIVKNIMLTIEEDMDIRLTDISFKQLMLFLLINIIRIRLGNSLKVSNTKK
HHHHHHHHHHHHHHHHHEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEECCCHH
ELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLILGMNKQINSNNIKKSLYLNEELASY
HEEEEEEEEECHHHHCCCCEEEEECHHHHHHHHHHHCCCCCCCCCCCHHHEEECHHHHHH
TKKIINLVSEESGINFNNDILLYEQLICHLNVTMHQMKSNVYLENPLLDNIKTKFCFLFT
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHH
VISSSIEIELKGKQITEGEIGYLTLHFQTSLERKYSKRESNKKASIVCPFSFGVSMLLKV
HHCCCEEEEECCCEECCCCEEEEEEEEEHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHE
KIEKRFDNIKIIETLREEDLKRDNFNKTIDFIIAFQEYENIQKPIFITTPLFTDEDENKL
EHHHCCCCHHHHHHHHHHHCCCCCCCCEEEHEEEEHHHHCCCCCEEEECCCCCCCCHHHH
KEFTNKIKEKDTSYKLMNRLMMSDYLIRELEHDDIYEAITYLTNLLIEKHYAEKEYLQSI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITREKSYPTNVGKGILFPHGDMKYIKQSVLCFARLKTPIKIRNGKDIKIILLLAYKKDDD
HHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCEEEEEEEEECCCCH
RKVFRELFKEISNLTEDENMLDILSKCDIEKVKDILI
HHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHCC
>Mature Secondary Structure
MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKYIDEWLSTFCNAYIKRK
CCCCCCHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLLLCNNKKVTLNDLSNKLYI
CCCCEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCEEEE
NKNIVREEISKLSVALNNYNLNISTKKGSGIYIEGDEKDIRIMLVSFLFKYIDKYRLNID
CHHHHHHHHHHHHEEEECEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCHH
EIEYFHIVDIIIVKNIMLTIEEDMDIRLTDISFKQLMLFLLINIIRIRLGNSLKVSNTKK
HHHHHHHHHHHHHHHHHEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEECCCHH
ELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLILGMNKQINSNNIKKSLYLNEELASY
HEEEEEEEEECHHHHCCCCEEEEECHHHHHHHHHHHCCCCCCCCCCCHHHEEECHHHHHH
TKKIINLVSEESGINFNNDILLYEQLICHLNVTMHQMKSNVYLENPLLDNIKTKFCFLFT
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHH
VISSSIEIELKGKQITEGEIGYLTLHFQTSLERKYSKRESNKKASIVCPFSFGVSMLLKV
HHCCCEEEEECCCEECCCCEEEEEEEEEHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHE
KIEKRFDNIKIIETLREEDLKRDNFNKTIDFIIAFQEYENIQKPIFITTPLFTDEDENKL
EHHHCCCCHHHHHHHHHHHCCCCCCCCEEEHEEEEHHHHCCCCCEEEECCCCCCCCHHHH
KEFTNKIKEKDTSYKLMNRLMMSDYLIRELEHDDIYEAITYLTNLLIEKHYAEKEYLQSI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITREKSYPTNVGKGILFPHGDMKYIKQSVLCFARLKTPIKIRNGKDIKIILLLAYKKDDD
HHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCEEEEEEEEECCCCH
RKVFRELFKEISNLTEDENMLDILSKCDIEKVKDILI
HHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]