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The map label for this gene is pyc [H]

Identifier: 126697587

GI number: 126697587

Start: 34867

End: 38298

Strand: Direct

Name: pyc [H]

Synonym: CD0021

Alternate gene names: 126697587

Gene position: 34867-38298 (Clockwise)

Preceding gene: 126697586

Following gene: 126697588

Centisome position: 0.81

GC content: 29.9

Gene sequence:

>3432_bases
ATGCTTAAAAAGTTTAATAAAATACTAGTGGCTAATAGAGGCGAAATAGCTATAAGAATATTTAGAGCCTGTTCAGAATT
GGGGATAAAAAGTGTTGGTATATACAGTAAGGAAGATAAGTATGGATTGTTTAGAACAAAAGCGGATGAATCATATTTGA
TAGGAGAAGGTAAAGGGCCAATAGATGCATATTTAGATATGGATGGAATAATAGACCTAGCAAAGAGAAAAAAAGTTGAT
GCTATACATCCAGGATATGGTTTTCTAGCGGAGAATGCAGAATTTGCTCGTAAATGTGAAGAGAATGGAATTACTTTTAT
AGGACCATCATCTAAGGTAATGAATATGATGGGGGATAAGATTAACTCTAAAAAAATCGCAAAAGAAGTTAATGTTCAAA
CTATACCAGGAGTAGAAAAAGCAATAAGAAGTACTGAAGAAGCAAAGGAAGTTGCAAACAAAATAGGATATCCTGTTATG
ATAAAAGCATCTAATGGCGGTGGCGGTAGAGGTATGAGAATTGTACATCGCGAAGAAGACTTAGAGCTTGAATATGAAAC
TGCTTGTAGTGAATCAAGAAAAGCTTTTGGAGAAGATATTATATTTATAGAAAAATATATAGCTGATCCAAAACATATAG
AAGTTCAAATATTAGGTGATAATTATGGAAATATAGTTCACTTATATGAAAGAGATTGTTCAGTTCAAAGAAGACATCAA
AAAATAATAGAATATGCACCAGCTTTTTCGTTAGATGATAAAGTAAGAAAAGAGATATGTGAAGATGCAGTTAAGTTATC
AAAACATGTGGGTTATTCTAATGCGGGAACATTAGAATTTTTAGTAGATGCAAATGGTGGGCATTATTTTATAGAGATGA
ACACAAGAGTACAGGTTGAACATACTGTAACAGAGATGGTTACAGGAATAGATATAGTTCAAAGTCAAATACTAATAGCC
CAAGGTTACAGCTTAGATAGTGAAGAAATTAATATAAAATCACAAGATGATGTGGAAATAAGAGGTTACTCTATCCAATG
TAGAATAACTACAGAAGACCCTAAGAATAAATTCATGCCTGATACAGGTAAAATTCAAGTTTATAGAACTGGTTCAGGAT
TTGGTATAAGACTAGATGGAGGAAATGGATTTACAGGGGCAAACATAAGTCCTCATTATGATAGTTTATTGGTTAAGACA
ATATCTTGGGATAGAACATTCCAAGGAGCAATAAATAAAACTATAAGATCTATAAAAGAACTTAGAGTTAGAGGTGTTAA
AACTAATGTAGGATTCCTAGTTAATGTTTTAAATAATCCTATATTCTCAAATGGTAAATGTAGTACTAAGTTTATAGATG
AAAATCCAGATTTATTTGAAATAACAGAAAGTAAAGACAGAGGAACAAAATTACTTCAATTTATAGGAGATGTAATTGTA
AATGATAATGCTTGTAAAGAAAAACCATTATTTGATGCATTACATGACCCAAGAATGGATAAGGATGGTTCAAAATCAGA
AGGAAGTAAAATACTTTTCGATAAGTTAGGTAAATCTGCATATATAGAAAAGATAAAAAATGATAAGAAATTACTATTAA
CAGATACAACAATGAGAGATGCACATCAATCATTATTAGCAACAAGAATAAGAACATATGACTTATTAAAAGCTGCTAAG
CCAACAGAAAAATATCAAAAGGATTTATTCTCACTTGAAATGTGGGGAGGAGCTACTTATGATGTTGCATATAGATTTTT
AAAAGAATCTCCTTGGCGTAGATTACAAAAGCTAAGAGAAGAAATACCAAGCATAATGTTCCAAATGTTGCTTAGAGCAT
CAAATGGAGTTGGATATAAAAACTATCCAGATAATGTAATAGAAGAATTTACAAAAGAATCTGCTAGACAAGGTATAGAT
GTATTTAGAATATTTGATTCATTAAACTGGGTTGAAAATATGAAACCATCTATTAATACAGCTTTAGAAACTGGAAAAAT
TGTTGAAGCAACTATGTGTTATACAGGTGATATACTAGATAAGACTAAAACTAAATACAATCTAGAATATTATATTAAAA
TGGCACAAGAATTAGAAAGCTTGGGAGCAGATATAATAGCAATAAAAGATATGTCAGGTCTTCTTAAACCATATTCAGCT
TACACACTAGTTAAAGAGTTAAAGAAAAATGTAAAAGCACCAATACATTTACACACTCATGATACAAGTGGAAATGGTGT
AGCAACTTGTTTAATGGCGTCAGAAGCTGGAGTAGACATAATTGATGCTGCATTAGAATCTATGGCAGGACTTACAAGTC
AGCCATCACTTAATGCTATAGTAGAGGCACTTAAGAATACAGAGAGAGATACAGGAATAGATTTATTTGGATATGATGAG
TTAGGAAAATATTATAAGGATTTAAGAAAAGTTTATAATAAATTTGAAAGTGATTTAACTAATTCTTGTGCAGAAATATA
TAATTTTGAAATACCAGGAGGCCAATATACAAACTTAAAACCTCAAGCTGATAGTTTAGGATTAGTTAATAGATTTGATG
AAGTTAAAGAAAAATATAAAGAAGCTAATGAAGTTGTAGGAGATATAATAAAAGTAACTCCATCTTCAAAAGTTGTAGGA
GACTTAGCTATCTTTATGACTAAAAATAAATTAGATAAAGATAATATAATAGAAGAAGGTAAAAATTTATCATTCCCAGA
TTCTGTTGTGGATTACTGTAAAGGTATGATTGGTCAACCAGAAGGTGGAATACCAAAAGATTTACAAGAGGTAGTTCTAA
AAGGTGAAGAAGCTATAACAGTAAGACCAGGTTCATTATTACCAGCAGAAGATTTTGATGAAATAGCTAAATATCTAAAT
GAAAAGTATGATATAAATGCTAATATAAGAAATGTTATAAGTTATGCTTTATATCCAAAAGTATATGAAGATTATATCAA
ACATCTACAACATTATAATGATATATCTAAACTTGAAAGTGATGTATTCTTCTATGGATTAAATAAAAATGAAGAATGTG
AAGTAGAAATAGAAGAAGGTAAGGTATTAACAATAAGATTAGTTGAAATTGGTGAAGTTAAGGAAAATGGATTTAGAACT
ATAGGATTTGAGTTAAATGGAATGGTTAGAGAAGTAGAAATAAAAGATAAGAATTTCTCTGGAAAAATTAATAATGTTGA
AAAAGCTGATATGAATGACCCTCTTCAAATTGGAGCAAGCATACCAGGAAAAGTTATAAAAATAATGGTTAAAGAAGAAG
ATGAAGTAAAAGCAAATCAACCATTAATCGTTATAGAGGCTATGAAGATGGAAACTATAATAGTTGCTAAGACTGATGGA
GTAATTAAGTCAATCAAAGTAAAAGAAGATGATATGGTTGAAGATAAACAATTATTAATGATAATGAAGTAA

Upstream 100 bases:

>100_bases
ATCTTATTAATTAAGGAACTTTCTTAAACATCTTCAAAAATAAAGTATTTTAGTCTATAATCTTTAATATTACACAAACA
ATAAAGGAGAAGAATAGAGT

Downstream 100 bases:

>100_bases
TTTAATTAAAATAAATTAAAAAGCACTCTGAAATGTTTAATAAAAAATGTTTTAGAGTGTTTTTATTTATTTTAATTAAA
TATTTGTTAAAAAAAAGAGG

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1143; Mature: 1143

Protein sequence:

>1143_residues
MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLFRTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVD
AIHPGYGFLAENAEFARKCEENGITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQILGDNYGNIVHLYERDCSVQRRHQ
KIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAGTLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIA
QGYSLDSEEINIKSQDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPHYDSLLVKT
ISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTKFIDENPDLFEITESKDRGTKLLQFIGDVIV
NDNACKEKPLFDALHDPRMDKDGSKSEGSKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAK
PTEKYQKDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPDNVIEEFTKESARQGID
VFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKTKTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSA
YTLVKELKKNVKAPIHLHTHDTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGYDE
LGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVKEKYKEANEVVGDIIKVTPSSKVVG
DLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCKGMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLN
EKYDINANIRNVISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEIGEVKENGFRT
IGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKIMVKEEDEVKANQPLIVIEAMKMETIIVAKTDG
VIKSIKVKEDDMVEDKQLLMIMK

Sequences:

>Translated_1143_residues
MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLFRTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVD
AIHPGYGFLAENAEFARKCEENGITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQILGDNYGNIVHLYERDCSVQRRHQ
KIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAGTLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIA
QGYSLDSEEINIKSQDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPHYDSLLVKT
ISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTKFIDENPDLFEITESKDRGTKLLQFIGDVIV
NDNACKEKPLFDALHDPRMDKDGSKSEGSKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAK
PTEKYQKDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPDNVIEEFTKESARQGID
VFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKTKTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSA
YTLVKELKKNVKAPIHLHTHDTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGYDE
LGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVKEKYKEANEVVGDIIKVTPSSKVVG
DLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCKGMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLN
EKYDINANIRNVISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEIGEVKENGFRT
IGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKIMVKEEDEVKANQPLIVIEAMKMETIIVAKTDG
VIKSIKVKEDDMVEDKQLLMIMK
>Mature_1143_residues
MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLFRTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVD
AIHPGYGFLAENAEFARKCEENGITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQILGDNYGNIVHLYERDCSVQRRHQ
KIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAGTLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIA
QGYSLDSEEINIKSQDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPHYDSLLVKT
ISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTKFIDENPDLFEITESKDRGTKLLQFIGDVIV
NDNACKEKPLFDALHDPRMDKDGSKSEGSKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAK
PTEKYQKDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPDNVIEEFTKESARQGID
VFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKTKTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSA
YTLVKELKKNVKAPIHLHTHDTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGYDE
LGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVKEKYKEANEVVGDIIKVTPSSKVVG
DLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCKGMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLN
EKYDINANIRNVISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEIGEVKENGFRT
IGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKIMVKEEDEVKANQPLIVIEAMKMETIIVAKTDG
VIKSIKVKEDDMVEDKQLLMIMK

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1150, Percent_Identity=47.9130434782609, Blast_Score=1096, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1150, Percent_Identity=47.9130434782609, Blast_Score=1096, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1150, Percent_Identity=47.9130434782609, Blast_Score=1096, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=495, Percent_Identity=41.010101010101, Blast_Score=390, Evalue=1e-108,
Organism=Homo sapiens, GI189095269, Length=462, Percent_Identity=44.1558441558442, Blast_Score=389, Evalue=1e-108,
Organism=Homo sapiens, GI65506442, Length=461, Percent_Identity=44.0347071583514, Blast_Score=387, Evalue=1e-107,
Organism=Homo sapiens, GI295821183, Length=461, Percent_Identity=44.0347071583514, Blast_Score=386, Evalue=1e-107,
Organism=Homo sapiens, GI134142062, Length=507, Percent_Identity=31.5581854043393, Blast_Score=251, Evalue=2e-66,
Organism=Homo sapiens, GI38679960, Length=513, Percent_Identity=32.3586744639376, Blast_Score=249, Evalue=7e-66,
Organism=Homo sapiens, GI38679977, Length=513, Percent_Identity=32.3586744639376, Blast_Score=249, Evalue=8e-66,
Organism=Homo sapiens, GI38679967, Length=513, Percent_Identity=32.3586744639376, Blast_Score=249, Evalue=8e-66,
Organism=Homo sapiens, GI38679974, Length=513, Percent_Identity=32.3586744639376, Blast_Score=249, Evalue=9e-66,
Organism=Homo sapiens, GI38679971, Length=513, Percent_Identity=32.3586744639376, Blast_Score=249, Evalue=9e-66,
Organism=Escherichia coli, GI1789654, Length=457, Percent_Identity=42.0131291028446, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI1786216, Length=266, Percent_Identity=25.9398496240602, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562816, Length=1134, Percent_Identity=47.7954144620811, Blast_Score=1096, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=468, Percent_Identity=42.3076923076923, Blast_Score=370, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17567343, Length=462, Percent_Identity=40.9090909090909, Blast_Score=342, Evalue=5e-94,
Organism=Caenorhabditis elegans, GI71997163, Length=441, Percent_Identity=34.4671201814059, Blast_Score=229, Evalue=6e-60,
Organism=Caenorhabditis elegans, GI71997168, Length=441, Percent_Identity=34.4671201814059, Blast_Score=229, Evalue=8e-60,
Organism=Caenorhabditis elegans, GI133931226, Length=495, Percent_Identity=30.1010101010101, Blast_Score=204, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1163, Percent_Identity=47.2914875322442, Blast_Score=1066, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1162, Percent_Identity=47.1600688468158, Blast_Score=1055, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=462, Percent_Identity=40.4761904761905, Blast_Score=332, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6324343, Length=513, Percent_Identity=32.7485380116959, Blast_Score=245, Evalue=3e-65,
Organism=Saccharomyces cerevisiae, GI6323863, Length=437, Percent_Identity=34.0961098398169, Blast_Score=234, Evalue=7e-62,
Organism=Drosophila melanogaster, GI24652212, Length=1149, Percent_Identity=48.7380330722367, Blast_Score=1105, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1149, Percent_Identity=48.7380330722367, Blast_Score=1105, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1149, Percent_Identity=48.7380330722367, Blast_Score=1105, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1149, Percent_Identity=48.7380330722367, Blast_Score=1105, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1149, Percent_Identity=48.7380330722367, Blast_Score=1105, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1165, Percent_Identity=48.4978540772532, Blast_Score=1102, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1165, Percent_Identity=48.4978540772532, Blast_Score=1102, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1165, Percent_Identity=48.4978540772532, Blast_Score=1102, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1165, Percent_Identity=48.4978540772532, Blast_Score=1102, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1165, Percent_Identity=48.4978540772532, Blast_Score=1102, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=458, Percent_Identity=41.703056768559, Blast_Score=377, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24651759, Length=412, Percent_Identity=42.4757281553398, Blast_Score=340, Evalue=4e-93,
Organism=Drosophila melanogaster, GI161076409, Length=517, Percent_Identity=30.7543520309478, Blast_Score=244, Evalue=3e-64,
Organism=Drosophila melanogaster, GI161076407, Length=517, Percent_Identity=30.7543520309478, Blast_Score=244, Evalue=4e-64,
Organism=Drosophila melanogaster, GI24586460, Length=517, Percent_Identity=30.7543520309478, Blast_Score=244, Evalue=4e-64,
Organism=Drosophila melanogaster, GI24586458, Length=517, Percent_Identity=30.7543520309478, Blast_Score=243, Evalue=4e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 128571; Mature: 128571

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLFRTKADESYLIGEGKGP
CCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCC
IDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEENGITFIGPSSKVMNMMGDK
CCEEECCHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHCCCEEECCCHHHHHHHCCC
INSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVMIKASNGGGGRGMRIVHREED
CCHHHHHHHCCCEECCCHHHHHHCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEECCC
LELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQILGDNYGNIVHLYERDCSVQRRHQ
CCEEHHHHHHHHHHHHCCCEEEHHHHHCCCCEEEEEEEECCCCCEEEEECCCCHHHHHHH
KIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAGTLEFLVDANGGHYFIEMNTRVQVE
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEECCEEEEH
HTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKSQDDVEIRGYSIQCRITTEDPKNKFMP
HHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCCCCCCC
DTGKIQVYRTGSGFGIRLDGGNGFTGANISPHYDSLLVKTISWDRTFQGAINKTIRSIKE
CCCCEEEEEECCCEEEEEECCCCCCCCCCCCCHHHHEEEEECCCCHHHHHHHHHHHHHHH
LRVRGVKTNVGFLVNVLNNPIFSNGKCSTKFIDENPDLFEITESKDRGTKLLQFIGDVIV
HHHCCCCCCHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHHHC
NDNACKEKPLFDALHDPRMDKDGSKSEGSKILFDKLGKSAYIEKIKNDKKLLLTDTTMRD
CCCCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHCCCCEEEEECCHHHH
AHQSLLATRIRTYDLLKAAKPTEKYQKDLFSLEMWGGATYDVAYRFLKESPWRRLQKLRE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEEECCCCHHHHHHHHHHCCHHHHHHHHHH
EIPSIMFQMLLRASNGVGYKNYPDNVIEEFTKESARQGIDVFRIFDSLNWVENMKPSINT
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHH
ALETGKIVEATMCYTGDILDKTKTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSA
HHHCCCEEEEEEECCCCHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHCHHHH
YTLVKELKKNVKAPIHLHTHDTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAI
HHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHH
VEALKNTERDTGIDLFGYDELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLK
HHHHHCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCC
PQADSLGLVNRFDEVKEKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHEEEEEECCCCCHHHHHHCC
KNLSFPDSVVDYCKGMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLN
CCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHC
EKYDINANIRNVISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCC
KVLTIRLVEIGEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGAS
CEEEEEEEEECCCCCCCCEEEEEEECCEEEEEEEECCCCCCCCCCCCCCCCCCCHHCCCC
IPGKVIKIMVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLM
CCCEEEEEEEECCCCCCCCCCEEEEEEECEEEEEEEECCCCEEEEEECCCCCCCCCCEEE
IMK
EEC
>Mature Secondary Structure
MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLFRTKADESYLIGEGKGP
CCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCC
IDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEENGITFIGPSSKVMNMMGDK
CCEEECCHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHCCCEEECCCHHHHHHHCCC
INSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVMIKASNGGGGRGMRIVHREED
CCHHHHHHHCCCEECCCHHHHHHCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEECCC
LELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQILGDNYGNIVHLYERDCSVQRRHQ
CCEEHHHHHHHHHHHHCCCEEEHHHHHCCCCEEEEEEEECCCCCEEEEECCCCHHHHHHH
KIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAGTLEFLVDANGGHYFIEMNTRVQVE
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEECCEEEEH
HTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKSQDDVEIRGYSIQCRITTEDPKNKFMP
HHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCCCCCCC
DTGKIQVYRTGSGFGIRLDGGNGFTGANISPHYDSLLVKTISWDRTFQGAINKTIRSIKE
CCCCEEEEEECCCEEEEEECCCCCCCCCCCCCHHHHEEEEECCCCHHHHHHHHHHHHHHH
LRVRGVKTNVGFLVNVLNNPIFSNGKCSTKFIDENPDLFEITESKDRGTKLLQFIGDVIV
HHHCCCCCCHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHHHC
NDNACKEKPLFDALHDPRMDKDGSKSEGSKILFDKLGKSAYIEKIKNDKKLLLTDTTMRD
CCCCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHCCCCEEEEECCHHHH
AHQSLLATRIRTYDLLKAAKPTEKYQKDLFSLEMWGGATYDVAYRFLKESPWRRLQKLRE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEEECCCCHHHHHHHHHHCCHHHHHHHHHH
EIPSIMFQMLLRASNGVGYKNYPDNVIEEFTKESARQGIDVFRIFDSLNWVENMKPSINT
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHH
ALETGKIVEATMCYTGDILDKTKTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSA
HHHCCCEEEEEEECCCCHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHCHHHH
YTLVKELKKNVKAPIHLHTHDTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAI
HHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHH
VEALKNTERDTGIDLFGYDELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLK
HHHHHCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCC
PQADSLGLVNRFDEVKEKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHEEEEEECCCCCHHHHHHCC
KNLSFPDSVVDYCKGMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLN
CCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHC
EKYDINANIRNVISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCC
KVLTIRLVEIGEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGAS
CEEEEEEEEECCCCCCCCEEEEEEECCEEEEEEEECCCCCCCCCCCCCCCCCCCHHCCCC
IPGKVIKIMVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLM
CCCEEEEEEEECCCCCCCCCCEEEEEEECEEEEEEEECCCCEEEEEECCCCCCCCCCEEE
IMK
EEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]