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The map label for this gene is rpiA [H]

Identifier: 126697018

GI number: 126697018

Start: 1412011

End: 1412706

Strand: Reverse

Name: rpiA [H]

Synonym: P9301_16801

Alternate gene names: 126697018

Gene position: 1412706-1412011 (Counterclockwise)

Preceding gene: 126697019

Following gene: 126697016

Centisome position: 86.04

GC content: 34.91

Gene sequence:

>696_bases
ATGAAACAAGTTGTTGCTGATGCAGCAATAAGGGAAGTAAAAAGTGACATGATTCTTGGATTAGGTTCTGGATCTACAGC
TGCGTTAATGATAAAAAGCCTTGCGGATGAAATGCGTTCTGGGAAACTCCAAAATATAAAAGGTGTTGCAACTTCTTTTC
AATCAGAAGTTTTAGCGCTTGAACTGAATATCCCCCTTATCGATTTAGCTTCTGTATCTCAAATTGATTTAGCTATTGAT
GGAGCAGATGAAGTTGATCCAGGATTTCAATTAATTAAAGGAGGAGGAGCATGCCATGTGAGAGAAAAGTTAGTAGCATC
TAAAGCTGATCAATTGCTGATTGTTGTTGATGAAACTAAACTTGTACAAAATTTAAATCTATCTTTCCCTTTACCTGTAG
AAGTTCTTCCAAATGCTTGGAAGCAAGTTCAGGAAGTTATCTCAGAGATGAAAGGTAGTTCTACTTTAAGAATGGCTACT
AAAAAAGCTGGCCCAGTTGTTACTGATCAAGGCAATCTAATTCTTGATGTATTATTTGATGATGGCATTAATAATCCGAA
AGACATTGAAATGAAGATTAATAATATTCCAGGAGTATTAGAAAATGGATTATTCGTTGATCTTACAGATAAAGTATTAG
TTGGTAAAATTGAAAACAATACTCCAGTGGTTTACTCACCATCAAGAGCTAGCTAA

Upstream 100 bases:

>100_bases
TATCAAACCAGAACCTCTCCCAGGTTTGACATAAAGCTCCCATTGAAATTTAATAATCTATAACCAATTAGAGAAAAAGA
TTTTGGATTCACAAACTCAA

Downstream 100 bases:

>100_bases
TCTTCAAATCTTATTTGTACTGAGTTAGCGTGACTATGCAAGCCCTCACTTTTAGCTAGATTAATAATATCAAGGCTATT
AACTTTTAAACTTTCTTCAT

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKQVVADAAIREVKSDMILGLGSGSTAALMIKSLADEMRSGKLQNIKGVATSFQSEVLALELNIPLIDLASVSQIDLAID
GADEVDPGFQLIKGGGACHVREKLVASKADQLLIVVDETKLVQNLNLSFPLPVEVLPNAWKQVQEVISEMKGSSTLRMAT
KKAGPVVTDQGNLILDVLFDDGINNPKDIEMKINNIPGVLENGLFVDLTDKVLVGKIENNTPVVYSPSRAS

Sequences:

>Translated_231_residues
MKQVVADAAIREVKSDMILGLGSGSTAALMIKSLADEMRSGKLQNIKGVATSFQSEVLALELNIPLIDLASVSQIDLAID
GADEVDPGFQLIKGGGACHVREKLVASKADQLLIVVDETKLVQNLNLSFPLPVEVLPNAWKQVQEVISEMKGSSTLRMAT
KKAGPVVTDQGNLILDVLFDDGINNPKDIEMKINNIPGVLENGLFVDLTDKVLVGKIENNTPVVYSPSRAS
>Mature_231_residues
MKQVVADAAIREVKSDMILGLGSGSTAALMIKSLADEMRSGKLQNIKGVATSFQSEVLALELNIPLIDLASVSQIDLAID
GADEVDPGFQLIKGGGACHVREKLVASKADQLLIVVDETKLVQNLNLSFPLPVEVLPNAWKQVQEVISEMKGSSTLRMAT
KKAGPVVTDQGNLILDVLFDDGINNPKDIEMKINNIPGVLENGLFVDLTDKVLVGKIENNTPVVYSPSRAS

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=218, Percent_Identity=40.3669724770642, Blast_Score=155, Evalue=4e-38,
Organism=Escherichia coli, GI1789280, Length=217, Percent_Identity=38.7096774193548, Blast_Score=118, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17551758, Length=208, Percent_Identity=38.9423076923077, Blast_Score=147, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6324669, Length=233, Percent_Identity=33.0472103004292, Blast_Score=121, Evalue=1e-28,
Organism=Drosophila melanogaster, GI281364072, Length=206, Percent_Identity=42.2330097087379, Blast_Score=140, Evalue=6e-34,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 24702; Mature: 24702

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQVVADAAIREVKSDMILGLGSGSTAALMIKSLADEMRSGKLQNIKGVATSFQSEVLAL
CCHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEE
ELNIPLIDLASVSQIDLAIDGADEVDPGFQLIKGGGACHVREKLVASKADQLLIVVDETK
EECCCEEECCCCCEEEEEECCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCEEEEEECHH
LVQNLNLSFPLPVEVLPNAWKQVQEVISEMKGSSTLRMATKKAGPVVTDQGNLILDVLFD
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCEEECCCCEEEEEEEC
DGINNPKDIEMKINNIPGVLENGLFVDLTDKVLVGKIENNTPVVYSPSRAS
CCCCCCCEEEEEECCCCCHHHCCEEEEEECCEEEEEECCCCCEEECCCCCC
>Mature Secondary Structure
MKQVVADAAIREVKSDMILGLGSGSTAALMIKSLADEMRSGKLQNIKGVATSFQSEVLAL
CCHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEE
ELNIPLIDLASVSQIDLAIDGADEVDPGFQLIKGGGACHVREKLVASKADQLLIVVDETK
EECCCEEECCCCCEEEEEECCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCEEEEEECHH
LVQNLNLSFPLPVEVLPNAWKQVQEVISEMKGSSTLRMATKKAGPVVTDQGNLILDVLFD
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCEEECCCCEEEEEEEC
DGINNPKDIEMKINNIPGVLENGLFVDLTDKVLVGKIENNTPVVYSPSRAS
CCCCCCCEEEEEECCCCCHHHCCEEEEEECCEEEEEECCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA