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The map label for this gene is tldD [C]

Identifier: 126696363

GI number: 126696363

Start: 884169

End: 885593

Strand: Direct

Name: tldD [C]

Synonym: P9301_10251

Alternate gene names: 126696363

Gene position: 884169-885593 (Clockwise)

Preceding gene: 126696362

Following gene: 126696364

Centisome position: 53.85

GC content: 34.95

Gene sequence:

>1425_bases
ATGCTTTCGTCACAAATCAAATCAAATGAAATAGTTTTTGGTAGTTGCAATAAAGATTTATTAGAAGAAATAATTTTTTA
CGGTATTGGACTTGGCGCTGATTTTGTAGAAATATTTATAGAGAATACCGACAACTCAAGTGTGCTAGCTGAAGAGGATT
TTATTACAAGTGTAAGTCCATCATTTGGAAGAGGTGCTGGTATCAGAATCTTCAAAGAAAAAAAGGATGGATTTGTAAGT
ACAAATGATTTAACAAAACATGGCTTGATGAGATCAGTAACTCAGGCTGTTGAGATGTTAGATATTGTAGTTAACAAAAA
AAGAGAAGTGTTTAACGGTTTAAATAAACATAGGGACTATAGTTTAAACAAGAAAAAATGGATTAATGAGGTTCCATCTA
TTAATGAGATAAGTGAAAAACTTTTAATCAGCACAAAGTCTCTAAAAAAAAATAATAAAATAATAACCAGAAAAGGAAGT
TACTCAAGAAATCTACAAGAAGTAATCATAGCCTCCAGCGACGGCACCTATGTTTCAGATATTAGGTTGCATCAAACAGT
TGGACTCAACTTAATTGCTAGTGATGCCCAATATAGATCTAGTGGAAGTAGAAGATTTGGATCGTCAGGAATGCCAAATG
AATTCAGATTATGGGATCACGAAAAAGCAGCTAATGATGTGTTTGAAAGCTCAATGAAGATGTTGTATGCAGATTATGTT
GAAGCGGGGCAAATGCCTGTCGTATTAGCTAATAAATTTGGTGGCGTTATATTCCACGAAGCCTGCGGTCATTTACTTGA
AACTACACAAATAGAGAGAGGAACAACACCATTTGAGAATAAATTGAATGAAAAAATTGCACATGAATCTGTAACAGCAA
TAGATGAAGGAATTTCAGAAGGATCATTTGGTTCATTATCAGTAGATGATGAAGGTATGGAACCCGAAAAATCAGTTCTT
ATAAAAGATGGAATTTTAAAAAAATTCATATCCGACAGGGCAGGGGAATTAAGAACAGGCCATAAAAGAACAGGAAGTGG
AAGAAGACAAAATTATTCTTTTGCTGCAGCTTCACGAATGAGAAATACTTATATAGCTAAAGGTGAGCACTCGAAGGACG
ATTTAATTAATAGTATTAGTGATGGTCTTTACTGCAAATCAATGGGTGGTGGCAGTGTAGGTGCTACCGGACAATTTAAT
TTTGCGGTAGAAGAAGGATATCTTATTAAAAATGGAAAATTAACTAATCCAGTAAAAGGAGCAACTTTGATTGGTGAGGC
TAAAGAAGTTATGCCGAAAATATCAATGTGTGGAAATGACCTCGAATTAGCTCCTGGATTTTGTGGATCCGTCAGTGGAA
GTGTCAACGTAACTGTTGGACAACCTCATATCAAGGTTGATTCAATCACTGTTGGCGGAAGATAG

Upstream 100 bases:

>100_bases
TACCAGTTATTAAGACTATACTTATTAAAACCTCTAGATAGCAAAGATTACCAACCTTCAATTAGATAATCTTTCATACA
GAGAAGACATATAGACTCAA

Downstream 100 bases:

>100_bases
GATATGAATTCAAAAGAAATAACAACTCAAATCTCTGAAGCTGCAGATTCACTAAATCTTAAAAAATGGGATTATGGTGC
AAGCTTTTCTAATGATTATT

Product: putative modulator of DNA gyrase; TldD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MLSSQIKSNEIVFGSCNKDLLEEIIFYGIGLGADFVEIFIENTDNSSVLAEEDFITSVSPSFGRGAGIRIFKEKKDGFVS
TNDLTKHGLMRSVTQAVEMLDIVVNKKREVFNGLNKHRDYSLNKKKWINEVPSINEISEKLLISTKSLKKNNKIITRKGS
YSRNLQEVIIASSDGTYVSDIRLHQTVGLNLIASDAQYRSSGSRRFGSSGMPNEFRLWDHEKAANDVFESSMKMLYADYV
EAGQMPVVLANKFGGVIFHEACGHLLETTQIERGTTPFENKLNEKIAHESVTAIDEGISEGSFGSLSVDDEGMEPEKSVL
IKDGILKKFISDRAGELRTGHKRTGSGRRQNYSFAAASRMRNTYIAKGEHSKDDLINSISDGLYCKSMGGGSVGATGQFN
FAVEEGYLIKNGKLTNPVKGATLIGEAKEVMPKISMCGNDLELAPGFCGSVSGSVNVTVGQPHIKVDSITVGGR

Sequences:

>Translated_474_residues
MLSSQIKSNEIVFGSCNKDLLEEIIFYGIGLGADFVEIFIENTDNSSVLAEEDFITSVSPSFGRGAGIRIFKEKKDGFVS
TNDLTKHGLMRSVTQAVEMLDIVVNKKREVFNGLNKHRDYSLNKKKWINEVPSINEISEKLLISTKSLKKNNKIITRKGS
YSRNLQEVIIASSDGTYVSDIRLHQTVGLNLIASDAQYRSSGSRRFGSSGMPNEFRLWDHEKAANDVFESSMKMLYADYV
EAGQMPVVLANKFGGVIFHEACGHLLETTQIERGTTPFENKLNEKIAHESVTAIDEGISEGSFGSLSVDDEGMEPEKSVL
IKDGILKKFISDRAGELRTGHKRTGSGRRQNYSFAAASRMRNTYIAKGEHSKDDLINSISDGLYCKSMGGGSVGATGQFN
FAVEEGYLIKNGKLTNPVKGATLIGEAKEVMPKISMCGNDLELAPGFCGSVSGSVNVTVGQPHIKVDSITVGGR
>Mature_474_residues
MLSSQIKSNEIVFGSCNKDLLEEIIFYGIGLGADFVEIFIENTDNSSVLAEEDFITSVSPSFGRGAGIRIFKEKKDGFVS
TNDLTKHGLMRSVTQAVEMLDIVVNKKREVFNGLNKHRDYSLNKKKWINEVPSINEISEKLLISTKSLKKNNKIITRKGS
YSRNLQEVIIASSDGTYVSDIRLHQTVGLNLIASDAQYRSSGSRRFGSSGMPNEFRLWDHEKAANDVFESSMKMLYADYV
EAGQMPVVLANKFGGVIFHEACGHLLETTQIERGTTPFENKLNEKIAHESVTAIDEGISEGSFGSLSVDDEGMEPEKSVL
IKDGILKKFISDRAGELRTGHKRTGSGRRQNYSFAAASRMRNTYIAKGEHSKDDLINSISDGLYCKSMGGGSVGATGQFN
FAVEEGYLIKNGKLTNPVKGATLIGEAKEVMPKISMCGNDLELAPGFCGSVSGSVNVTVGQPHIKVDSITVGGR

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=456, Percent_Identity=31.359649122807, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI1790682, Length=454, Percent_Identity=21.3656387665198, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51831; Mature: 51831

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSSQIKSNEIVFGSCNKDLLEEIIFYGIGLGADFVEIFIENTDNSSVLAEEDFITSVSP
CCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEECCHHHHCCCC
SFGRGAGIRIFKEKKDGFVSTNDLTKHGLMRSVTQAVEMLDIVVNKKREVFNGLNKHRDY
CCCCCCCEEEEEECCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SLNKKKWINEVPSINEISEKLLISTKSLKKNNKIITRKGSYSRNLQEVIIASSDGTYVSD
CCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEECCCCCEEEE
IRLHQTVGLNLIASDAQYRSSGSRRFGSSGMPNEFRLWDHEKAANDVFESSMKMLYADYV
EEEEHECCCEEEECCCHHHCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHH
EAGQMPVVLANKFGGVIFHEACGHLLETTQIERGTTPFENKLNEKIAHESVTAIDEGISE
HCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
GSFGSLSVDDEGMEPEKSVLIKDGILKKFISDRAGELRTGHKRTGSGRRQNYSFAAASRM
CCCCEEECCCCCCCHHHHEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
RNTYIAKGEHSKDDLINSISDGLYCKSMGGGSVGATGQFNFAVEEGYLIKNGKLTNPVKG
HHHEEECCCCCHHHHHHHHHCCEEEECCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCC
ATLIGEAKEVMPKISMCGNDLELAPGFCGSVSGSVNVTVGQPHIKVDSITVGGR
CEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEECCC
>Mature Secondary Structure
MLSSQIKSNEIVFGSCNKDLLEEIIFYGIGLGADFVEIFIENTDNSSVLAEEDFITSVSP
CCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEECCHHHHCCCC
SFGRGAGIRIFKEKKDGFVSTNDLTKHGLMRSVTQAVEMLDIVVNKKREVFNGLNKHRDY
CCCCCCCEEEEEECCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SLNKKKWINEVPSINEISEKLLISTKSLKKNNKIITRKGSYSRNLQEVIIASSDGTYVSD
CCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEECCCCCEEEE
IRLHQTVGLNLIASDAQYRSSGSRRFGSSGMPNEFRLWDHEKAANDVFESSMKMLYADYV
EEEEHECCCEEEECCCHHHCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHH
EAGQMPVVLANKFGGVIFHEACGHLLETTQIERGTTPFENKLNEKIAHESVTAIDEGISE
HCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
GSFGSLSVDDEGMEPEKSVLIKDGILKKFISDRAGELRTGHKRTGSGRRQNYSFAAASRM
CCCCEEECCCCCCCHHHHEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
RNTYIAKGEHSKDDLINSISDGLYCKSMGGGSVGATGQFNFAVEEGYLIKNGKLTNPVKG
HHHEEECCCCCHHHHHHHHHCCEEEECCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCC
ATLIGEAKEVMPKISMCGNDLELAPGFCGSVSGSVNVTVGQPHIKVDSITVGGR
CEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]