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The map label for this gene is thiL [H]

Identifier: 126695361

GI number: 126695361

Start: 25193

End: 26179

Strand: Reverse

Name: thiL [H]

Synonym: P9301_00231

Alternate gene names: 126695361

Gene position: 26179-25193 (Counterclockwise)

Preceding gene: 126695362

Following gene: 126695359

Centisome position: 1.59

GC content: 30.4

Gene sequence:

>987_bases
ATGCATAAAAAAACATTAGAAGATATAGGAGAAAAAGAATTAATCAATAGGCTAGGAAAATTTATGCCTAAAAACCAAAT
TTCAGATGATTGCGCTTTAATCAAAACTAAAAATGAAAATTTACTTGTTAATACTGATTGTTTGGTAGAAAATGTTCATT
TCAATGACATTAATATTTGTCCTATGGACCTTGGGTGGAAAGCAGTTGTAAGCAACATCTCAGACTTATTATCTAGTGGC
AGTAAGAAAACTATTGGAATTACAATAAGCCTAGTTCTACCTCCTAGAACTGAGTGGATTTGGGTTGAAGAATTATACAA
AGGAATTAATAAAGCATTAAAAGAATATGGCGGGATGATTCTAGGGGGAGATTGCTCAAAGGGGGATGACAAAGTCATTT
CAATTACAGCCTTTGGAATACAAGGTGAACTTGAATTAAGAAGAAACGCATGCAAACCAGGAGAGATAATTTTAACTACA
GGAATTCATGGTCTTAGCAAACTAGGATTTTTGATGCAAAATAAAATTAATTTCGATAATCAATTTTCTCTTAATGAAAG
ATTAATTATTAAGTCCATTGAACATTTTTGTCGACCTAGAGTTTACCCAAATTTTCTAAATAATCTCCTCAAAACTCGCT
CCAATAAAAAAATTAAGAGAATAGGATGCACTGATAGCAGTGATGGTTTATTTCAAGCATTACAAGATCTAGCAATGGCT
AGCAGCTGCAAAGCGATAATAGATTATGAAAAAATACCTAAAGATAAAGATTGGCCTAATGGAGATAAATGGGATGAATA
TTATTTTTTTGGGGGTGAAGATTATGAATTAGTGTTCTCATTGCCAAAAAAATGGGCAAAGAATTTATCTAAACTTGATA
AAAATATTAACGAGATTGGTTTTTTTACTGATGGTAAACCATCAATAGAATTTAATGATAATAAAAAAAACAAAATATTA
AATAATACGACTTTCAAACACTTTTAG

Upstream 100 bases:

>100_bases
GGTTACGTTGTTGATGGATTTGATGTATTAGAAGAGCTTACTAAAGATGACACAATCATTTCAATTGATGTTTTAGATGG
GATTGAAAACCTCAAATTAA

Downstream 100 bases:

>100_bases
TTACTCCCAATTCTTAGCAACAATCTCTGCTAAATCTACAACTCTCTGACTATAACCCCACTCATTGTCATACCATGCAA
GGACCTTAACAAGGTTATCT

Product: putative thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MHKKTLEDIGEKELINRLGKFMPKNQISDDCALIKTKNENLLVNTDCLVENVHFNDINICPMDLGWKAVVSNISDLLSSG
SKKTIGITISLVLPPRTEWIWVEELYKGINKALKEYGGMILGGDCSKGDDKVISITAFGIQGELELRRNACKPGEIILTT
GIHGLSKLGFLMQNKINFDNQFSLNERLIIKSIEHFCRPRVYPNFLNNLLKTRSNKKIKRIGCTDSSDGLFQALQDLAMA
SSCKAIIDYEKIPKDKDWPNGDKWDEYYFFGGEDYELVFSLPKKWAKNLSKLDKNINEIGFFTDGKPSIEFNDNKKNKIL
NNTTFKHF

Sequences:

>Translated_328_residues
MHKKTLEDIGEKELINRLGKFMPKNQISDDCALIKTKNENLLVNTDCLVENVHFNDINICPMDLGWKAVVSNISDLLSSG
SKKTIGITISLVLPPRTEWIWVEELYKGINKALKEYGGMILGGDCSKGDDKVISITAFGIQGELELRRNACKPGEIILTT
GIHGLSKLGFLMQNKINFDNQFSLNERLIIKSIEHFCRPRVYPNFLNNLLKTRSNKKIKRIGCTDSSDGLFQALQDLAMA
SSCKAIIDYEKIPKDKDWPNGDKWDEYYFFGGEDYELVFSLPKKWAKNLSKLDKNINEIGFFTDGKPSIEFNDNKKNKIL
NNTTFKHF
>Mature_328_residues
MHKKTLEDIGEKELINRLGKFMPKNQISDDCALIKTKNENLLVNTDCLVENVHFNDINICPMDLGWKAVVSNISDLLSSG
SKKTIGITISLVLPPRTEWIWVEELYKGINKALKEYGGMILGGDCSKGDDKVISITAFGIQGELELRRNACKPGEIILTT
GIHGLSKLGFLMQNKINFDNQFSLNERLIIKSIEHFCRPRVYPNFLNNLLKTRSNKKIKRIGCTDSSDGLFQALQDLAMA
SSCKAIIDYEKIPKDKDWPNGDKWDEYYFFGGEDYELVFSLPKKWAKNLSKLDKNINEIGFFTDGKPSIEFNDNKKNKIL
NNTTFKHF

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=287, Percent_Identity=31.3588850174216, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 37312; Mature: 37312

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKKTLEDIGEKELINRLGKFMPKNQISDDCALIKTKNENLLVNTDCLVENVHFNDINIC
CCCCHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEECHHEEEEECCCCCEEE
PMDLGWKAVVSNISDLLSSGSKKTIGITISLVLPPRTEWIWVEELYKGINKALKEYGGMI
ECCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCEEEHHHHHHHHHHHHHHHCCEE
LGGDCSKGDDKVISITAFGIQGELELRRNACKPGEIILTTGIHGLSKLGFLMQNKINFDN
EECCCCCCCCCEEEEEEECCCCHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCC
QFSLNERLIIKSIEHFCRPRVYPNFLNNLLKTRSNKKIKRIGCTDSSDGLFQALQDLAMA
CCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHH
SSCKAIIDYEKIPKDKDWPNGDKWDEYYFFGGEDYELVFSLPKKWAKNLSKLDKNINEIG
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCEEEEEHHHHHHHHHHHHHHCCHHHCC
FFTDGKPSIEFNDNKKNKILNNTTFKHF
CEECCCCCEEECCCCCCCEECCCCCCCC
>Mature Secondary Structure
MHKKTLEDIGEKELINRLGKFMPKNQISDDCALIKTKNENLLVNTDCLVENVHFNDINIC
CCCCHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEECHHEEEEECCCCCEEE
PMDLGWKAVVSNISDLLSSGSKKTIGITISLVLPPRTEWIWVEELYKGINKALKEYGGMI
ECCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCEEEHHHHHHHHHHHHHHHCCEE
LGGDCSKGDDKVISITAFGIQGELELRRNACKPGEIILTTGIHGLSKLGFLMQNKINFDN
EECCCCCCCCCEEEEEEECCCCHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCC
QFSLNERLIIKSIEHFCRPRVYPNFLNNLLKTRSNKKIKRIGCTDSSDGLFQALQDLAMA
CCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHH
SSCKAIIDYEKIPKDKDWPNGDKWDEYYFFGGEDYELVFSLPKKWAKNLSKLDKNINEIG
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCEEEEEHHHHHHHHHHHHHHCCHHHCC
FFTDGKPSIEFNDNKKNKILNNTTFKHF
CEECCCCCEEECCCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA