BacMap

Definition	Burkholderia pseudomallei 1106a chromosome I, complete genome.
Accession	NC_009076
Length	3,988,455

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The map label for this gene is fabG [H]

Identifier: 126455374

GI number: 126455374

Start: 3865305

End: 3866063

Strand: Direct

Name: fabG [H]

Synonym: BURPS1106A_3960

Alternate gene names: 126455374

Gene position: 3865305-3866063 (Clockwise)

Preceding gene: 126454521

Following gene: 126452282

Centisome position: 96.91

GC content: 73.78

Gene sequence:

>759_bases
ATGTTCTCCGAACGCTGCCTCGCAGGCGGCACCTACCTCGTCACGGGCGCGTCGTCCGGCATCGGCCGCGCGGCGGCGAT
CGCGATCGCGCAACTCGGCGGGCGGCTCGTCCTCGGCGGGCGCGACCCGGCGCGCCTCGCCGACACGCTCGCCGCGCTGC
CCGGCGACGGCCATGCATCGCACGCGGCCGCGCTCGACGACGCGGACGCGGCCGCCGACTGGGTCGGCGCGCTCGCCGAG
ACCCACGGCCCGCTCGCGGGCGTGTTCCATGCGGCGGGCGTCGAGCTGATCCGCCCGGCGCGCATGACGGCGCAGGCGCA
ACTCGAGCAGGTATTCGGCGCGAGTCTGTACGCCGCGTTCGGCATCGCGCGCGCCGCCGCGAAGAAGAACGTCATCGCGG
ACGGCGGCTCGGTCGTCTACATGTCCTCCGTCGCCGGCTCGACCGGGCAGGTCGGCATGACCGCCTATTCGGCGGCGAAG
GCGGGCATCGAAGGGCTCGTGCGTTCGCTCGCATGCGAACTCGCGCCGCGCCGGATTCGTGCCAATGCGATCGCCGCGGG
CGCGGTCAAGACGGAAATGCATGCGCGCCTGACGCGCGGCACGCCCGAGGACGCGCTCGCCGCGTACGAGGCGAGCCATC
TGCTCGGCTTCGGCGAGCCCGGCGACGTCGCGGCCGCGGCGATCTTTCTGTTGAGCGGCGCGAGCCGCTGGATTACCGGC
ACGTCGCTCGTCGTCGACGGCGGCTACAAGGTGCGCTGA

Upstream 100 bases:

>100_bases
TGCGGCTCGCGATGTTCGGCTTCGGCGTCGGCTATTCGTGGGCGTCGGCATCGCTCGCCGTCGAACCGCTTTCCGTCATC
GACAACATCGAGCTATGACC

Downstream 100 bases:

>100_bases
TGACTCCACGGCTGATCGTCGCCGGCTGCGGCGCATTCGCGCGCGAGCTGATCAATTGGGCCGACGATGCGGCGCACGCC
GGCATCGGCCAGCGGATCAC

Product: short chain dehydrogenase/reductase family oxidoreductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MFSERCLAGGTYLVTGASSGIGRAAAIAIAQLGGRLVLGGRDPARLADTLAALPGDGHASHAAALDDADAAADWVGALAE
THGPLAGVFHAAGVELIRPARMTAQAQLEQVFGASLYAAFGIARAAAKKNVIADGGSVVYMSSVAGSTGQVGMTAYSAAK
AGIEGLVRSLACELAPRRIRANAIAAGAVKTEMHARLTRGTPEDALAAYEASHLLGFGEPGDVAAAAIFLLSGASRWITG
TSLVVDGGYKVR

Sequences:

>Translated_252_residues
MFSERCLAGGTYLVTGASSGIGRAAAIAIAQLGGRLVLGGRDPARLADTLAALPGDGHASHAAALDDADAAADWVGALAE
THGPLAGVFHAAGVELIRPARMTAQAQLEQVFGASLYAAFGIARAAAKKNVIADGGSVVYMSSVAGSTGQVGMTAYSAAK
AGIEGLVRSLACELAPRRIRANAIAAGAVKTEMHARLTRGTPEDALAAYEASHLLGFGEPGDVAAAAIFLLSGASRWITG
TSLVVDGGYKVR
>Mature_252_residues
MFSERCLAGGTYLVTGASSGIGRAAAIAIAQLGGRLVLGGRDPARLADTLAALPGDGHASHAAALDDADAAADWVGALAE
THGPLAGVFHAAGVELIRPARMTAQAQLEQVFGASLYAAFGIARAAAKKNVIADGGSVVYMSSVAGSTGQVGMTAYSAAK
AGIEGLVRSLACELAPRRIRANAIAAGAVKTEMHARLTRGTPEDALAAYEASHLLGFGEPGDVAAAAIFLLSGASRWITG
TSLVVDGGYKVR

Specific function: Catalyzes A Reversible Reduction Of 5-Ketoglutanate To Form D-Gluconate. Dependent On Nadp, Almost Inactive With NAD. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=34.9593495934959, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI15277342, Length=248, Percent_Identity=32.258064516129, Blast_Score=94, Evalue=8e-20,
Organism=Homo sapiens, GI32483357, Length=252, Percent_Identity=29.7619047619048, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=30.6451612903226, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=29.8039215686275, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI19923817, Length=254, Percent_Identity=27.9527559055118, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI5031737, Length=261, Percent_Identity=27.5862068965517, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI66933014, Length=139, Percent_Identity=30.2158273381295, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI10190704, Length=253, Percent_Identity=26.4822134387352, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=28.1746031746032, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=33.4645669291339, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1787526, Length=245, Percent_Identity=28.1632653061224, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI87082160, Length=251, Percent_Identity=28.2868525896414, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1787905, Length=245, Percent_Identity=27.7551020408163, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=26.3779527559055, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786812, Length=260, Percent_Identity=29.2307692307692, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=29.3877551020408, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788459, Length=241, Percent_Identity=27.8008298755187, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=28.9256198347107, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1786701, Length=184, Percent_Identity=30.9782608695652, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=27.0916334661355, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=27.3092369477912, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=243, Percent_Identity=31.6872427983539, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=32.4, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=31.4516129032258, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=29.9595141700405, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI115534694, Length=238, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=258, Percent_Identity=25.968992248062, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=29.1187739463602, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17561402, Length=263, Percent_Identity=26.9961977186312, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=27.7992277992278, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=27.7992277992278, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=26.953125, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=257, Percent_Identity=27.2373540856031, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=259, Percent_Identity=25.8687258687259, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=27.9693486590038, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=27.7566539923954, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=256, Percent_Identity=30.078125, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=27.3076923076923, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=27.027027027027, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=254, Percent_Identity=25.5905511811024, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=254, Percent_Identity=26.3779527559055, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=26.3358778625954, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=251, Percent_Identity=32.2709163346614, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571526, Length=246, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=33.4661354581673, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21357041, Length=244, Percent_Identity=31.5573770491803, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=32.8, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24644337, Length=121, Percent_Identity=38.0165289256198, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=29.9595141700405, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25283; Mature: 25283

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSERCLAGGTYLVTGASSGIGRAAAIAIAQLGGRLVLGGRDPARLADTLAALPGDGHAS
CCCCCEECCCCEEEECCCCCCCHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCCCCCC
HAAALDDADAAADWVGALAETHGPLAGVFHAAGVELIRPARMTAQAQLEQVFGASLYAAF
HHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIARAAAKKNVIADGGSVVYMSSVAGSTGQVGMTAYSAAKAGIEGLVRSLACELAPRRIR
HHHHHHHHCCEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANAIAAGAVKTEMHARLTRGTPEDALAAYEASHLLGFGEPGDVAAAAIFLLSGASRWITG
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHEEC
TSLVVDGGYKVR
CEEEECCCEECC
>Mature Secondary Structure
MFSERCLAGGTYLVTGASSGIGRAAAIAIAQLGGRLVLGGRDPARLADTLAALPGDGHAS
CCCCCEECCCCEEEECCCCCCCHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCCCCCC
HAAALDDADAAADWVGALAETHGPLAGVFHAAGVELIRPARMTAQAQLEQVFGASLYAAF
HHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIARAAAKKNVIADGGSVVYMSSVAGSTGQVGMTAYSAAKAGIEGLVRSLACELAPRRIR
HHHHHHHHCCEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANAIAAGAVKTEMHARLTRGTPEDALAAYEASHLLGFGEPGDVAAAAIFLLSGASRWITG
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHEEC
TSLVVDGGYKVR
CEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]