Click here to switch to the map view.

The map label for this gene is epsM [H]

Identifier: 126452282

GI number: 126452282

Start: 3866063

End: 3866695

Strand: Direct

Name: epsM [H]

Synonym: BURPS1106A_3961

Alternate gene names: 126452282

Gene position: 3866063-3866695 (Clockwise)

Preceding gene: 126455374

Following gene: 126453073

Centisome position: 96.93

GC content: 68.56

Gene sequence:

>633_bases
ATGACTCCACGGCTGATCGTCGCCGGCTGCGGCGCATTCGCGCGCGAGCTGATCAATTGGGCCGACGATGCGGCGCACGC
CGGCATCGGCCAGCGGATCACCGGCTTTCTCGACGCGAATCCCGCCGCACTCGCCGGCTTCCCGTATCGCGCCGAATGGC
TCGGCGACATCGATGCCTACACGCCCGAGGACGGCGACGAGCTGATCGTCGCGATCGGCGATCCCAATGCGAAGCGGGAC
GTCGTCGAGCGTCTGCGCGCGCGCGGCGCGCGCTTCGGCAGCCTGCGGCATCCGAGCGCCGTCGTCGCGCGAAGCGCGTC
GCTCGGCGCGGGCGTCGTACTCTGCCCGCACGCGGTCGTCTCGGCGGACGCGCAAATCGGCGATTTCGTCGCGGTCAACG
TGCTGTCGAGCATCGGCCATGACGTGAAGGTCGGCGCGTATTCGACGCTGAGTTCACACGTCGATCTGATGGGCCACGTC
GAGACCGGCGAGCGCGTGTTCTTCGGCTCCGGCGCGAAGATTCTGCCGAAAGTGAGGATCGGCGCCGGCGCGAAGATCGG
TGCCGGCGCGACCGTCATGCGCTCGGCGCCCGAAAACGCCGTGCTCTATACGATGCCCGCGAAGAAGCTCTGA

Upstream 100 bases:

>100_bases
CCGGCGACGTCGCGGCCGCGGCGATCTTTCTGTTGAGCGGCGCGAGCCGCTGGATTACCGGCACGTCGCTCGTCGTCGAC
GGCGGCTACAAGGTGCGCTG

Downstream 100 bases:

>100_bases
CATGAATTTCGATACGGACCTCCTCCATCGCCACTGGCATCTCGGCTGTCACCGCCGGGAGCTTCCGAACGACGGCGATT
TCGTGCGCTTCGACACCGCA

Product: hexapeptide repeat-containing transferase

Products: UDP-2,3-Bis(3-Hydroxytetradecanoyl)Glucosamine; [Acyl-Carrier Protein]. [C]

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MTPRLIVAGCGAFARELINWADDAAHAGIGQRITGFLDANPAALAGFPYRAEWLGDIDAYTPEDGDELIVAIGDPNAKRD
VVERLRARGARFGSLRHPSAVVARSASLGAGVVLCPHAVVSADAQIGDFVAVNVLSSIGHDVKVGAYSTLSSHVDLMGHV
ETGERVFFGSGAKILPKVRIGAGAKIGAGATVMRSAPENAVLYTMPAKKL

Sequences:

>Translated_210_residues
MTPRLIVAGCGAFARELINWADDAAHAGIGQRITGFLDANPAALAGFPYRAEWLGDIDAYTPEDGDELIVAIGDPNAKRD
VVERLRARGARFGSLRHPSAVVARSASLGAGVVLCPHAVVSADAQIGDFVAVNVLSSIGHDVKVGAYSTLSSHVDLMGHV
ETGERVFFGSGAKILPKVRIGAGAKIGAGATVMRSAPENAVLYTMPAKKL
>Mature_209_residues
TPRLIVAGCGAFARELINWADDAAHAGIGQRITGFLDANPAALAGFPYRAEWLGDIDAYTPEDGDELIVAIGDPNAKRDV
VERLRARGARFGSLRHPSAVVARSASLGAGVVLCPHAVVSADAQIGDFVAVNVLSSIGHDVKVGAYSTLSSHVDLMGHVE
TGERVFFGSGAKILPKVRIGAGAKIGAGATVMRSAPENAVLYTMPAKKL

Specific function: May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018357
- InterPro:   IPR013817
- InterPro:   IPR020019
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: 2.3.1.- [C]

Molecular weight: Translated: 21827; Mature: 21696

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPRLIVAGCGAFARELINWADDAAHAGIGQRITGFLDANPAALAGFPYRAEWLGDIDAY
CCCCEEEECCCHHHHHHHHHHHHHHHCCCCHHEEEEECCCCHHEECCCCCHHHCCCCCCC
TPEDGDELIVAIGDPNAKRDVVERLRARGARFGSLRHPSAVVARSASLGAGVVLCPHAVV
CCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCEEECCHHHH
SADAQIGDFVAVNVLSSIGHDVKVGAYSTLSSHVDLMGHVETGERVFFGSGAKILPKVRI
CCCCCCCHHHHHHHHHHCCCCEEECHHHHHHHHHHEEEEECCCCEEEECCCCEECEEEEE
GAGAKIGAGATVMRSAPENAVLYTMPAKKL
CCCCCCCCCHHEECCCCCCEEEEECCCCCC
>Mature Secondary Structure 
TPRLIVAGCGAFARELINWADDAAHAGIGQRITGFLDANPAALAGFPYRAEWLGDIDAY
CCCEEEECCCHHHHHHHHHHHHHHHCCCCHHEEEEECCCCHHEECCCCCHHHCCCCCCC
TPEDGDELIVAIGDPNAKRDVVERLRARGARFGSLRHPSAVVARSASLGAGVVLCPHAVV
CCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCEEECCHHHH
SADAQIGDFVAVNVLSSIGHDVKVGAYSTLSSHVDLMGHVETGERVFFGSGAKILPKVRI
CCCCCCCHHHHHHHHHHCCCCEEECHHHHHHHHHHEEEEECCCCEEEECCCCEECEEEEE
GAGAKIGAGATVMRSAPENAVLYTMPAKKL
CCCCCCCCCHHEECCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-3-O-(3-Hydroxytetradecanoyl)Glucosamine; (R)-3-Hydroxytetradecanoyl-[Acyl-Carrier Protein] [C]

Specific reaction: UDP-3-O-(3-Hydroxytetradecanoyl)Glucosamine + (R)-3-Hydroxytetradecanoyl-[Acyl-Carrier Protein] = UDP-2,3-Bis(3-Hydroxytetradecanoyl)Glucosamine + [Acyl-Carrier Protein]. [C]

General reaction: Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969506; 9384377 [H]