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The map label for this gene is fabH [H]

Identifier: 126454521

GI number: 126454521

Start: 3864238

End: 3865302

Strand: Direct

Name: fabH [H]

Synonym: BURPS1106A_3959

Alternate gene names: 126454521

Gene position: 3864238-3865302 (Clockwise)

Preceding gene: 126453659

Following gene: 126455374

Centisome position: 96.89

GC content: 69.3

Gene sequence:

>1065_bases
GTGAGCACGCCGCACGCCGTCGCGGGACGTGAGATCTGCCTGGGCGGTGCCCGGCTCGCCGGCATCGTCTCGTGCCTGCC
GTCGCGCGAGATCGACAACGATGCGTTCGTCGCACGCTTCGGCGAGGGACCGGTCAGGGACGTCGTCAAGATGATCGGCG
TGGAGCGCCGCCGCTGGGCGGCCGAACACGAGACGACGAGCGATCTGTGCCGCGCGGCCGGCGCGCACCTGCTGCGCGAG
CTCGACTGGCGGCCGGACAGCGTCGACGCCGTGATCTTCGTCTCGCAGACGCCCGACTACCGGCTACCCGGCACGTCGTT
CGTGCTGCAGGCGGCATGGGGCTTGCCGCAGGCGAGCATCGCGCTCGACGTCAACCTCGGCTGCTCCGGCTATCCGCAGG
CGCTGTGGCTCGGCACGAACCTGATCGCCACGGGCGCCGCGCGGCGCGTGCTGCTCGCCGTCGGCGATACGATCAGCAAG
CTCGTCGATCCGAACGACCGGTCGACGAGCCTGCTGTTCGGCGACGCCGGCACCGTGACGGCGCTCGAAGCCGATGGCGC
GGCGGGCGACGCGCACTTCGTGATCGGCGCGGACGGCCGCGGCGCGCGCAACCTGATCGTGCCGTCGGGCGCGTGCCGCC
CATACGACGCGCAGGCCGACGCGCGCCTCGCGCAGCGCTCGCCCGGCCACCTGTTCATGGACGGCGGCGAGATATTCAAT
TTCACGCTGCAAGGCATTCCGCCGCTCGTCGCGCATACGCTCGCGTTCGCGAACACGAGCGTCGACCAGTACGACGCGTT
CCTGTTTCATCAGGCGAACCTCTTCATGCTGAAGCATCTCGCGAAGAAAGCGGGGCTGCCCGCCGAGCGCGTGCCGATCA
ACATCGGCACATACGGCAATACGAGCTGCGCGTCCATTCCGCTACTGATGACGACCGCGCTGCAAGCGCAGCTCGCCGCG
CGCCCGATGCGGCTCGCGATGTTCGGCTTCGGCGTCGGCTATTCGTGGGCGTCGGCATCGCTCGCCGTCGAACCGCTTTC
CGTCATCGACAACATCGAGCTATGA

Upstream 100 bases:

>100_bases
CCGACGACTGCTTCGGCGTGCTGCTCAACGGCCAGGCGCTCGGCAACTGCAAGACGGTCGCCGATATCGACGCGCTCGTC
GCGGCGCAAAAGGGCTGATC

Downstream 100 bases:

>100_bases
CCATGTTCTCCGAACGCTGCCTCGCAGGCGGCACCTACCTCGTCACGGGCGCGTCGTCCGGCATCGGCCGCGCGGCGGCG
ATCGCGATCGCGCAACTCGG

Product: 3-oxoacyl-(acyl-carrier-protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSTPHAVAGREICLGGARLAGIVSCLPSREIDNDAFVARFGEGPVRDVVKMIGVERRRWAAEHETTSDLCRAAGAHLLRE
LDWRPDSVDAVIFVSQTPDYRLPGTSFVLQAAWGLPQASIALDVNLGCSGYPQALWLGTNLIATGAARRVLLAVGDTISK
LVDPNDRSTSLLFGDAGTVTALEADGAAGDAHFVIGADGRGARNLIVPSGACRPYDAQADARLAQRSPGHLFMDGGEIFN
FTLQGIPPLVAHTLAFANTSVDQYDAFLFHQANLFMLKHLAKKAGLPAERVPINIGTYGNTSCASIPLLMTTALQAQLAA
RPMRLAMFGFGVGYSWASASLAVEPLSVIDNIEL

Sequences:

>Translated_354_residues
MSTPHAVAGREICLGGARLAGIVSCLPSREIDNDAFVARFGEGPVRDVVKMIGVERRRWAAEHETTSDLCRAAGAHLLRE
LDWRPDSVDAVIFVSQTPDYRLPGTSFVLQAAWGLPQASIALDVNLGCSGYPQALWLGTNLIATGAARRVLLAVGDTISK
LVDPNDRSTSLLFGDAGTVTALEADGAAGDAHFVIGADGRGARNLIVPSGACRPYDAQADARLAQRSPGHLFMDGGEIFN
FTLQGIPPLVAHTLAFANTSVDQYDAFLFHQANLFMLKHLAKKAGLPAERVPINIGTYGNTSCASIPLLMTTALQAQLAA
RPMRLAMFGFGVGYSWASASLAVEPLSVIDNIEL
>Mature_353_residues
STPHAVAGREICLGGARLAGIVSCLPSREIDNDAFVARFGEGPVRDVVKMIGVERRRWAAEHETTSDLCRAAGAHLLREL
DWRPDSVDAVIFVSQTPDYRLPGTSFVLQAAWGLPQASIALDVNLGCSGYPQALWLGTNLIATGAARRVLLAVGDTISKL
VDPNDRSTSLLFGDAGTVTALEADGAAGDAHFVIGADGRGARNLIVPSGACRPYDAQADARLAQRSPGHLFMDGGEIFNF
TLQGIPPLVAHTLAFANTSVDQYDAFLFHQANLFMLKHLAKKAGLPAERVPINIGTYGNTSCASIPLLMTTALQAQLAAR
PMRLAMFGFGVGYSWASASLAVEPLSVIDNIEL

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=323, Percent_Identity=26.9349845201238, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 37580; Mature: 37449

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPHAVAGREICLGGARLAGIVSCLPSREIDNDAFVARFGEGPVRDVVKMIGVERRRWA
CCCCCCCCCCEEEECCHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHCCHHHHHH
AEHETTSDLCRAAGAHLLRELDWRPDSVDAVIFVSQTPDYRLPGTSFVLQAAWGLPQASI
HCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCEE
ALDVNLGCSGYPQALWLGTNLIATGAARRVLLAVGDTISKLVDPNDRSTSLLFGDAGTVT
EEEEECCCCCCCCEEEECCHHHHHHHHHEEEEHHHHHHHHHCCCCCCCCEEEEECCCCEE
ALEADGAAGDAHFVIGADGRGARNLIVPSGACRPYDAQADARLAQRSPGHLFMDGGEIFN
EEECCCCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCHHHHHHHCCCCEEEEECCEEEE
FTLQGIPPLVAHTLAFANTSVDQYDAFLFHQANLFMLKHLAKKAGLPAERVPINIGTYGN
EEECCCCHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHCEEEECCCCC
TSCASIPLLMTTALQAQLAARPMRLAMFGFGVGYSWASASLAVEPLSVIDNIEL
CCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEECHHHHHCCCCC
>Mature Secondary Structure 
STPHAVAGREICLGGARLAGIVSCLPSREIDNDAFVARFGEGPVRDVVKMIGVERRRWA
CCCCCCCCCEEEECCHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHCCHHHHHH
AEHETTSDLCRAAGAHLLRELDWRPDSVDAVIFVSQTPDYRLPGTSFVLQAAWGLPQASI
HCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCEE
ALDVNLGCSGYPQALWLGTNLIATGAARRVLLAVGDTISKLVDPNDRSTSLLFGDAGTVT
EEEEECCCCCCCCEEEECCHHHHHHHHHEEEEHHHHHHHHHCCCCCCCCEEEEECCCCEE
ALEADGAAGDAHFVIGADGRGARNLIVPSGACRPYDAQADARLAQRSPGHLFMDGGEIFN
EEECCCCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCHHHHHHHCCCCEEEEECCEEEE
FTLQGIPPLVAHTLAFANTSVDQYDAFLFHQANLFMLKHLAKKAGLPAERVPINIGTYGN
EEECCCCHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHCEEEECCCCC
TSCASIPLLMTTALQAQLAARPMRLAMFGFGVGYSWASASLAVEPLSVIDNIEL
CCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEECHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]