Click here to switch to the map view.

The map label for this gene is panE

Identifier: 126455021

GI number: 126455021

Start: 922085

End: 923107

Strand: Direct

Name: panE

Synonym: BURPS1106A_0940

Alternate gene names: NA

Gene position: 922085-923107 (Clockwise)

Preceding gene: 126452824

Following gene: 126452729

Centisome position: 23.12

GC content: 73.8

Gene sequence:

>1023_bases
ATGGCGACGATCTGCGTCTATGGCGCGGGCGCGGTCGGCTGCTATCTCGGCGGCCGGCTGCTCGCGGGCGGCGCGGATGT
CGCGCTGATCGGCCGCGCGCGGATCGGCGACGAGTTGCGCGCGCACGGGCTCGCGCTGTCCGATTATCGCGGCCGCGACG
TGCGCGTGCCGCCATCCGCGATTGCGTTCTCGACGGCGGATGCGGCGCTCGCCACCGCCGAACTCGTGCTCGTCACGGTG
AAATCGGCGGCGACGCCCGCCGTCGGCGCGGCGCTCGCACGCATCGCGCGGCCCGGCGCGGTCGTCATCAGCTTTCAGAA
CGGCGTGCGCAACGCGGACGTGCTGCGCGCCGCGCTGCCCGGCGCGACGGTGCTTGCCGGCATGGTGCCGTTCAACGTCA
TCGCGCGCGGCGAGGGCCGATTCCATCAAGGCACGGCGGGCGCGCTGCAGGCCGAGGCCGCGCCCGCGCTGCGCCGCTTC
GCGGCCGCGTTCGAGCGCGCGGGGCTGCCGCTCGTGCCGTGCGAGGACATGCGCGCGGTTCAGTGGGCGAAGTTGCTGCT
CAATCTCAACAACGCGATCAACGCGCTCGCGAACCGGCCGCTGAAGGAGGAACTCGCGGCGCGCAGCTATCGGCGCTGTC
TCGCGCTCGCGCAGACCGAGGCGCTGCGCGTGCTGTCGGCGGCGCAGATTCGTCCCGCCCGGCTCACGCCGTTGCCGGCC
GCGTGGGTGCCGCGGGTGCTGAGCGTGCCGGACCCGCTGTTCGCGCGGCTCGGCCGGAAGATGCTCGAGATCGATCCGCT
CGCGCGTTCGTCGATGTCCGATGATCTGGCTGCGAAACGCGCGACCGAGATCGACTGGATCAACGGCGAGATCGTGCGCC
TTGCCGGGCAGCTCGGGTGCGCGGCGCCCGTCAACGCACGCCTTTGCGCGCTCGTCCACGAGGCGGAGCGCGCTGCGGCG
CGGCCGGCGTGGGGCGGCGACGCGCTGCTCGCCGAATTGCGCGAGGCGGCGCGGGCGGGATAG

Upstream 100 bases:

>100_bases
CGCCGGCTTGCGCGGCGACGTGCGCGACGCGGTCGAGCGGCGCGTCGGGCCGGTGCGTGTGGGCGCGCGCAACGCGCGCG
TCTGAGCCGCGCCGCGCGCG

Downstream 100 bases:

>100_bases
CCGAGGCGCGCGCTCGCAGGCATGGCATGCATCGGCCGCCCGGCCGTCGCGATGCGCGCGGCCGGATAGCCTGGGTGCGT
GCCGATATCGGCGCGGCGGC

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MATICVYGAGAVGCYLGGRLLAGGADVALIGRARIGDELRAHGLALSDYRGRDVRVPPSAIAFSTADAALATAELVLVTV
KSAATPAVGAALARIARPGAVVISFQNGVRNADVLRAALPGATVLAGMVPFNVIARGEGRFHQGTAGALQAEAAPALRRF
AAAFERAGLPLVPCEDMRAVQWAKLLLNLNNAINALANRPLKEELAARSYRRCLALAQTEALRVLSAAQIRPARLTPLPA
AWVPRVLSVPDPLFARLGRKMLEIDPLARSSMSDDLAAKRATEIDWINGEIVRLAGQLGCAAPVNARLCALVHEAERAAA
RPAWGGDALLAELREAARAG

Sequences:

>Translated_340_residues
MATICVYGAGAVGCYLGGRLLAGGADVALIGRARIGDELRAHGLALSDYRGRDVRVPPSAIAFSTADAALATAELVLVTV
KSAATPAVGAALARIARPGAVVISFQNGVRNADVLRAALPGATVLAGMVPFNVIARGEGRFHQGTAGALQAEAAPALRRF
AAAFERAGLPLVPCEDMRAVQWAKLLLNLNNAINALANRPLKEELAARSYRRCLALAQTEALRVLSAAQIRPARLTPLPA
AWVPRVLSVPDPLFARLGRKMLEIDPLARSSMSDDLAAKRATEIDWINGEIVRLAGQLGCAAPVNARLCALVHEAERAAA
RPAWGGDALLAELREAARAG
>Mature_339_residues
ATICVYGAGAVGCYLGGRLLAGGADVALIGRARIGDELRAHGLALSDYRGRDVRVPPSAIAFSTADAALATAELVLVTVK
SAATPAVGAALARIARPGAVVISFQNGVRNADVLRAALPGATVLAGMVPFNVIARGEGRFHQGTAGALQAEAAPALRRFA
AAFERAGLPLVPCEDMRAVQWAKLLLNLNNAINALANRPLKEELAARSYRRCLALAQTEALRVLSAAQIRPARLTPLPAA
WVPRVLSVPDPLFARLGRKMLEIDPLARSSMSDDLAAKRATEIDWINGEIVRLAGQLGCAAPVNARLCALVHEAERAAAR
PAWGGDALLAELREAARAG

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 35511; Mature: 35379

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATICVYGAGAVGCYLGGRLLAGGADVALIGRARIGDELRAHGLALSDYRGRDVRVPPSA
CCEEEEECCCHHHHHHCCEEEECCCCEEEEECHHHCHHHHHCCCEEECCCCCCEECCCHH
IAFSTADAALATAELVLVTVKSAATPAVGAALARIARPGAVVISFQNGVRNADVLRAALP
HEECCHHHHHHHHHEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHCC
GATVLAGMVPFNVIARGEGRFHQGTAGALQAEAAPALRRFAAAFERAGLPLVPCEDMRAV
CHHHHHHHHCHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
QWAKLLLNLNNAINALANRPLKEELAARSYRRCLALAQTEALRVLSAAQIRPARLTPLPA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
AWVPRVLSVPDPLFARLGRKMLEIDPLARSSMSDDLAAKRATEIDWINGEIVRLAGQLGC
HHHHHHHCCCCHHHHHHCHHHHHCCHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHCCC
AAPVNARLCALVHEAERAAARPAWGGDALLAELREAARAG
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATICVYGAGAVGCYLGGRLLAGGADVALIGRARIGDELRAHGLALSDYRGRDVRVPPSA
CEEEEECCCHHHHHHCCEEEECCCCEEEEECHHHCHHHHHCCCEEECCCCCCEECCCHH
IAFSTADAALATAELVLVTVKSAATPAVGAALARIARPGAVVISFQNGVRNADVLRAALP
HEECCHHHHHHHHHEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHCC
GATVLAGMVPFNVIARGEGRFHQGTAGALQAEAAPALRRFAAAFERAGLPLVPCEDMRAV
CHHHHHHHHCHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
QWAKLLLNLNNAINALANRPLKEELAARSYRRCLALAQTEALRVLSAAQIRPARLTPLPA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
AWVPRVLSVPDPLFARLGRKMLEIDPLARSSMSDDLAAKRATEIDWINGEIVRLAGQLGC
HHHHHHHCCCCHHHHHHCHHHHHCCHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHCCC
AAPVNARLCALVHEAERAAARPAWGGDALLAELREAARAG
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]