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The map label for this gene is 126454252

Identifier: 126454252

GI number: 126454252

Start: 610524

End: 611300

Strand: Direct

Name: 126454252

Synonym: BURPS1106A_0638

Alternate gene names: NA

Gene position: 610524-611300 (Clockwise)

Preceding gene: 126453886

Following gene: 126453370

Centisome position: 15.31

GC content: 67.44

Gene sequence:

>777_bases
GTGACGAATCGAACGCCGAATCAACCGTTCGCCCGCCCGGCGCGTTTTGCGCAAGCGGAGTGGCAGGCGCGCGTGCAACT
GGCGGCCGCGTACCGGATCTTCGATCATCTCGGCTGGAGCGAGCTGATCTACAACCACATCTCGCTGCGCGTGCCGGGCG
AAGACACGCATTTTCTGATCAACCCGTTCGGGCTGCACTACCGCGAGGTCTGCGCCTCGAACCTCGTGAAGGTCGACGTC
GACGGCCATTCGGTCGGCCACGCGGACTGGCCGTTCAATCCGGCAGGCGTCACGTTCCATGCGGCGATTCACGCGGCGCT
GCCCGATGCGCACTGCGTGATGCACGTGCACACGACGCCGACGATGGCCGTGTGCGCGACGCGCCGCGGGCTGTCGTTCT
CCAATTTCTATGCGGCGCAATTGCACGGCCGCGTCGCGTATCACGATTTCGAGGGCATCACCGTGCGGCCCGACGAAGGC
CGGCGGATCGTCGACAGCGCGGCCGGGCGGCCGGTGCTGCTGTTGCGCAATCACGGGCCGGTCGCGATCGGCCGCACGCT
CGCGCATGCGTTCTCGCTGATGTGGCTGCTCCATCGCGCGTGCGAGGTGCAGGTCGCGACGCATGCGCTCGGCGAGCCGC
TCGAGATCGACGCGCCGATTCTCGACGCGTGCGCGCGCGATTCGCTGAATCTCGATCCGCGCCACGGCGCGGGGCAGGAT
GCGTTCGATGCGCTGCAGCGCATCGTCGACCGGATCGATCCGGGTTATCGCAGCTGA

Upstream 100 bases:

>100_bases
CGCGCTCAATCGCGCGCTGCTGTTCCTGTAGCGCGGGCCCGCCGCCGGCGGGCTTGCATGCGCCGGCGCCCGCAACGATG
TCATTCGACGAGGAGCGCAC

Downstream 100 bases:

>100_bases
ATGCGGATGCCGCGATTGTTCTGATCAAAATCGTTCGACGGATTGACTTCAAATATTAAGAATCAATTGATCCGGAATGC
TTTCATTCGGAAGCGAAATT

Product: aldolase II superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MTNRTPNQPFARPARFAQAEWQARVQLAAAYRIFDHLGWSELIYNHISLRVPGEDTHFLINPFGLHYREVCASNLVKVDV
DGHSVGHADWPFNPAGVTFHAAIHAALPDAHCVMHVHTTPTMAVCATRRGLSFSNFYAAQLHGRVAYHDFEGITVRPDEG
RRIVDSAAGRPVLLLRNHGPVAIGRTLAHAFSLMWLLHRACEVQVATHALGEPLEIDAPILDACARDSLNLDPRHGAGQD
AFDALQRIVDRIDPGYRS

Sequences:

>Translated_258_residues
MTNRTPNQPFARPARFAQAEWQARVQLAAAYRIFDHLGWSELIYNHISLRVPGEDTHFLINPFGLHYREVCASNLVKVDV
DGHSVGHADWPFNPAGVTFHAAIHAALPDAHCVMHVHTTPTMAVCATRRGLSFSNFYAAQLHGRVAYHDFEGITVRPDEG
RRIVDSAAGRPVLLLRNHGPVAIGRTLAHAFSLMWLLHRACEVQVATHALGEPLEIDAPILDACARDSLNLDPRHGAGQD
AFDALQRIVDRIDPGYRS
>Mature_257_residues
TNRTPNQPFARPARFAQAEWQARVQLAAAYRIFDHLGWSELIYNHISLRVPGEDTHFLINPFGLHYREVCASNLVKVDVD
GHSVGHADWPFNPAGVTFHAAIHAALPDAHCVMHVHTTPTMAVCATRRGLSFSNFYAAQLHGRVAYHDFEGITVRPDEGR
RIVDSAAGRPVLLLRNHGPVAIGRTLAHAFSLMWLLHRACEVQVATHALGEPLEIDAPILDACARDSLNLDPRHGAGQDA
FDALQRIVDRIDPGYRS

Specific function: Unknown

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family [H]

Homologues:

Organism=Homo sapiens, GI29826323, Length=257, Percent_Identity=41.2451361867704, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI29826325, Length=257, Percent_Identity=41.2451361867704, Blast_Score=164, Evalue=6e-41,
Organism=Homo sapiens, GI29826321, Length=257, Percent_Identity=41.2451361867704, Blast_Score=164, Evalue=7e-41,
Organism=Homo sapiens, GI29826319, Length=257, Percent_Identity=41.2451361867704, Blast_Score=164, Evalue=8e-41,
Organism=Homo sapiens, GI297307158, Length=261, Percent_Identity=34.8659003831418, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI9257192, Length=261, Percent_Identity=34.8659003831418, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI89276787, Length=261, Percent_Identity=34.8659003831418, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI9257190, Length=261, Percent_Identity=34.8659003831418, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI297307160, Length=261, Percent_Identity=34.8659003831418, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI9943848, Length=201, Percent_Identity=38.3084577114428, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI9951927, Length=201, Percent_Identity=38.3084577114428, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI62912453, Length=201, Percent_Identity=38.3084577114428, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI115533216, Length=190, Percent_Identity=40.5263157894737, Blast_Score=141, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI115533218, Length=190, Percent_Identity=40.5263157894737, Blast_Score=140, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI71989544, Length=193, Percent_Identity=35.7512953367876, Blast_Score=117, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI71989555, Length=193, Percent_Identity=35.7512953367876, Blast_Score=117, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI71989550, Length=193, Percent_Identity=35.7512953367876, Blast_Score=117, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI71989541, Length=193, Percent_Identity=35.7512953367876, Blast_Score=117, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71989560, Length=193, Percent_Identity=35.7512953367876, Blast_Score=117, Evalue=5e-27,
Organism=Drosophila melanogaster, GI281363755, Length=198, Percent_Identity=31.3131313131313, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI281363751, Length=198, Percent_Identity=31.3131313131313, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24655690, Length=198, Percent_Identity=31.3131313131313, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24655685, Length=198, Percent_Identity=31.3131313131313, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281363761, Length=198, Percent_Identity=31.3131313131313, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281363759, Length=198, Percent_Identity=31.3131313131313, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281363753, Length=198, Percent_Identity=31.3131313131313, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281363763, Length=198, Percent_Identity=31.3131313131313, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI281363757, Length=198, Percent_Identity=31.3131313131313, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI17136738, Length=198, Percent_Identity=31.3131313131313, Blast_Score=108, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: NA

Molecular weight: Translated: 28591; Mature: 28460

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNRTPNQPFARPARFAQAEWQARVQLAAAYRIFDHLGWSELIYNHISLRVPGEDTHFLI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEEEECCCCCEEEE
NPFGLHYREVCASNLVKVDVDGHSVGHADWPFNPAGVTFHAAIHAALPDAHCVMHVHTTP
CCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEEEEEEEHHHCCCCEEEEEEECCC
TMAVCATRRGLSFSNFYAAQLHGRVAYHDFEGITVRPDEGRRIVDSAAGRPVLLLRNHGP
HHHHHHHHCCCCHHHHHHHHHCCEEEEEECCCEEECCCCCCCHHHHCCCCEEEEEECCCC
VAIGRTLAHAFSLMWLLHRACEVQVATHALGEPLEIDAPILDACARDSLNLDPRHGAGQD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCH
AFDALQRIVDRIDPGYRS
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TNRTPNQPFARPARFAQAEWQARVQLAAAYRIFDHLGWSELIYNHISLRVPGEDTHFLI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEEEECCCCCEEEE
NPFGLHYREVCASNLVKVDVDGHSVGHADWPFNPAGVTFHAAIHAALPDAHCVMHVHTTP
CCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEEEEEEEHHHCCCCEEEEEEECCC
TMAVCATRRGLSFSNFYAAQLHGRVAYHDFEGITVRPDEGRRIVDSAAGRPVLLLRNHGP
HHHHHHHHCCCCHHHHHHHHHCCEEEEEECCCEEECCCCCCCHHHHCCCCEEEEEECCCC
VAIGRTLAHAFSLMWLLHRACEVQVATHALGEPLEIDAPILDACARDSLNLDPRHGAGQD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCH
AFDALQRIVDRIDPGYRS
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]