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The map label for this gene is nagA [H]

Identifier: 126453864

GI number: 126453864

Start: 519433

End: 520536

Strand: Direct

Name: nagA [H]

Synonym: BURPS1106A_0552

Alternate gene names: 126453864

Gene position: 519433-520536 (Clockwise)

Preceding gene: 126454767

Following gene: 126452572

Centisome position: 13.02

GC content: 70.11

Gene sequence:

>1104_bases
ATGCTGACCGGAAACATACTGACCGCCGAAGGCTGGATCCACGGCACGCTCGAATTCGAGAACGGCCGGATCACCACGCT
GTCGGGCGACGCGGCGGACCCGTCGAACAACGATGCGCCCTACATCCTGCCCGGCTTCATCGATCTGCACGTGCACGGCG
CGGGCGGCGCGGACGTGATGGAGGGCGGCGACGCGATCGAGACGATCGCGCGCACGCACGCGCGCTACGGCACGACGAGC
CTGCTCGCGACGACGATGACCGCGCCGCGCGACGAGCTGATGCGCGTCGTCGCGGAGCTGGGCGACGTCGCGCGCACGCG
CACGCCGGGCGGCTCGCGCGTGCTCGGCGTGCATCTCGAAGGCCCGTACATCAATCCCGGCAAGCTCGGCGCTCAGCCGG
ACGCGGCGGTGTCCGCGGCGCTCGACGAGGTGCTGAAGTATCTGTCGATCGCGCCGATCCGCGTGGTCACGCTCGCGCCG
GAGATCGCCGGGCACATCGAGATCATCTCGGAGATGGCCGCGCGCGGCGTGCGCGTGCAGCTCGGCCATTCGCTCGGCAC
GTACGACGACGCGGTCGCCGCGCTCAAGCACGGCGCGTGCGGCTTCACGCACCTGTTCAACGCGATGTCGCCGCTGCATC
ACCGCAATCCCGGCATCGTCGGCGCGGCGCTCGCGCACGCCGAATACGCGGAGATCATCCCCGATCTGCTGCACGTGCAC
CCGGGCGCGATCCGCGCGGCGCTGCGCGCGATCCCGCGGCTGTACGTGGTGACCGACAGCACGTCGGCCACCGGCATGCC
CGACGGCGAATACCGGCTCGGCAGCCAGCGCGTGACGAAGTGCCTGGGCGGCGTGCGCCTCGCCGACGGCACGCTCGCCG
GCAGCACGCTGACGATGGATCAGGCGCTGCGCAATCTCGTGTCGCTCGGCCTGCCGATCGCCGACGTGTCGAGCCGGATG
TCGCGCTACGCGGCCGACTATCTCGGGCTCGCCGATCGCGGCCGCATCGCGCGTGGCGCGTGGGCCGATCTCGCCGTGTT
CGACCGCGAGCTGAATCTGACCGCAACCTTCGTCGAAGGAGAATCGATTGTCGAATATGCTTAA

Upstream 100 bases:

>100_bases
GACACGACAGACTGTCCGCGGCGGCCCGGCGACTCGCAAGCCCTCTCGCAAGCAGCAAGCAGCACCGCCCCCATACGCAT
CACCAGATATAGAGAACGTC

Downstream 100 bases:

>100_bases
CGAGGCGCGCGAATCGGCGCGCGTCGTCGCCGCGCAACTGGCGGACACGCGCCGCGTCGAGGCGCTCGCGCAGCACCTCG
CCACGCATGCGCCGCAAGTC

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MLTGNILTAEGWIHGTLEFENGRITTLSGDAADPSNNDAPYILPGFIDLHVHGAGGADVMEGGDAIETIARTHARYGTTS
LLATTMTAPRDELMRVVAELGDVARTRTPGGSRVLGVHLEGPYINPGKLGAQPDAAVSAALDEVLKYLSIAPIRVVTLAP
EIAGHIEIISEMAARGVRVQLGHSLGTYDDAVAALKHGACGFTHLFNAMSPLHHRNPGIVGAALAHAEYAEIIPDLLHVH
PGAIRAALRAIPRLYVVTDSTSATGMPDGEYRLGSQRVTKCLGGVRLADGTLAGSTLTMDQALRNLVSLGLPIADVSSRM
SRYAADYLGLADRGRIARGAWADLAVFDRELNLTATFVEGESIVEYA

Sequences:

>Translated_367_residues
MLTGNILTAEGWIHGTLEFENGRITTLSGDAADPSNNDAPYILPGFIDLHVHGAGGADVMEGGDAIETIARTHARYGTTS
LLATTMTAPRDELMRVVAELGDVARTRTPGGSRVLGVHLEGPYINPGKLGAQPDAAVSAALDEVLKYLSIAPIRVVTLAP
EIAGHIEIISEMAARGVRVQLGHSLGTYDDAVAALKHGACGFTHLFNAMSPLHHRNPGIVGAALAHAEYAEIIPDLLHVH
PGAIRAALRAIPRLYVVTDSTSATGMPDGEYRLGSQRVTKCLGGVRLADGTLAGSTLTMDQALRNLVSLGLPIADVSSRM
SRYAADYLGLADRGRIARGAWADLAVFDRELNLTATFVEGESIVEYA
>Mature_367_residues
MLTGNILTAEGWIHGTLEFENGRITTLSGDAADPSNNDAPYILPGFIDLHVHGAGGADVMEGGDAIETIARTHARYGTTS
LLATTMTAPRDELMRVVAELGDVARTRTPGGSRVLGVHLEGPYINPGKLGAQPDAAVSAALDEVLKYLSIAPIRVVTLAP
EIAGHIEIISEMAARGVRVQLGHSLGTYDDAVAALKHGACGFTHLFNAMSPLHHRNPGIVGAALAHAEYAEIIPDLLHVH
PGAIRAALRAIPRLYVVTDSTSATGMPDGEYRLGSQRVTKCLGGVRLADGTLAGSTLTMDQALRNLVSLGLPIADVSSRM
SRYAADYLGLADRGRIARGAWADLAVFDRELNLTATFVEGESIVEYA

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=412, Percent_Identity=32.5242718446602, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI224922791, Length=407, Percent_Identity=32.6781326781327, Blast_Score=164, Evalue=2e-40,
Organism=Escherichia coli, GI1786892, Length=337, Percent_Identity=34.4213649851632, Blast_Score=148, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17553768, Length=343, Percent_Identity=32.3615160349854, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI19920392, Length=345, Percent_Identity=34.7826086956522, Blast_Score=174, Evalue=6e-44,
Organism=Drosophila melanogaster, GI281361140, Length=360, Percent_Identity=33.3333333333333, Blast_Score=168, Evalue=6e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 38679; Mature: 38679

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTGNILTAEGWIHGTLEFENGRITTLSGDAADPSNNDAPYILPGFIDLHVHGAGGADVM
CCCCCEEEECCEEEEEEEECCCEEEEEECCCCCCCCCCCCEEECCEEEEEEECCCCCHHH
EGGDAIETIARTHARYGTTSLLATTMTAPRDELMRVVAELGDVARTRTPGGSRVLGVHLE
CCCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
GPYINPGKLGAQPDAAVSAALDEVLKYLSIAPIRVVTLAPEIAGHIEIISEMAARGVRVQ
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCEEEE
LGHSLGTYDDAVAALKHGACGFTHLFNAMSPLHHRNPGIVGAALAHAEYAEIIPDLLHVH
ECCCCCCHHHHHHHHHCCCCCHHHHHHHHCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
PGAIRAALRAIPRLYVVTDSTSATGMPDGEYRLGSQRVTKCLGGVRLADGTLAGSTLTMD
CHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCEEECCCCCCCEEEHH
QALRNLVSLGLPIADVSSRMSRYAADYLGLADRGRIARGAWADLAVFDRELNLTATFVEG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHEECCCCEEEEEECC
ESIVEYA
CHHHCCC
>Mature Secondary Structure
MLTGNILTAEGWIHGTLEFENGRITTLSGDAADPSNNDAPYILPGFIDLHVHGAGGADVM
CCCCCEEEECCEEEEEEEECCCEEEEEECCCCCCCCCCCCEEECCEEEEEEECCCCCHHH
EGGDAIETIARTHARYGTTSLLATTMTAPRDELMRVVAELGDVARTRTPGGSRVLGVHLE
CCCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
GPYINPGKLGAQPDAAVSAALDEVLKYLSIAPIRVVTLAPEIAGHIEIISEMAARGVRVQ
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCEEEE
LGHSLGTYDDAVAALKHGACGFTHLFNAMSPLHHRNPGIVGAALAHAEYAEIIPDLLHVH
ECCCCCCHHHHHHHHHCCCCCHHHHHHHHCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
PGAIRAALRAIPRLYVVTDSTSATGMPDGEYRLGSQRVTKCLGGVRLADGTLAGSTLTMD
CHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCEEECCCCCCCEEEHH
QALRNLVSLGLPIADVSSRMSRYAADYLGLADRGRIARGAWADLAVFDRELNLTATFVEG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHEECCCCEEEEEECC
ESIVEYA
CHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA