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The map label for this gene is glmS [H]

Identifier: 126452572

GI number: 126452572

Start: 520529

End: 521536

Strand: Direct

Name: glmS [H]

Synonym: BURPS1106A_0553

Alternate gene names: 126452572

Gene position: 520529-521536 (Clockwise)

Preceding gene: 126453864

Following gene: 126451463

Centisome position: 13.05

GC content: 73.71

Gene sequence:

>1008_bases
ATGCTTAACGAGGCGCGCGAATCGGCGCGCGTCGTCGCCGCGCAACTGGCGGACACGCGCCGCGTCGAGGCGCTCGCGCA
GCACCTCGCCACGCATGCGCCGCAAGTCGCGCTCACCGTCGCGCGCGGCAGCTCCGATCACGCGGCGAGCTACTTCGCGA
GCCTGACGATGAGCCGCCTCGGCGTGCCCGTCGCGTCGCTGCCGATGTCGGTCGCCACGCTGCAGCAGGCGCCGCTGAAA
GTGCGGGGCCAGCTCGCGCTCGCGTTCTCGCAATCGGGCAAGAGCCCGGATCTCGTCAACACGATGGCCGCGCTGCGCGA
GGCGGGCGCGCTGACGGTGGCCGCCGTCAACGTGCTGCCGTCGCCGCTCGCGCACGCGTGCGAGCACCCGTTGCCGCTGC
TCGCCGGCCCGGAGCTGTCGGTCGCCGCGACGAAGAGCTACATCGCGATGCTGTCGATTGCCGCGCAGCTCGTCGCGTTC
TGGCAGCGCGACGCCGCGCTCGCGTCCGCGCTGCGCGGCCTGCCCGACGCGCTCGAGCAGGCGGGCCGGCTCGACTGGTC
GAGCGCCGTCGACGAACTGCGCGACGTCGAGCGGATGATCGTGATCGGCCGCGGGCTCGGTCTCGCGATCGCGCAGGAGG
CGGCGCTCAAGCTGAAGGAGACCTCGGGCATCCAGGCCGAGGCGTTCTCGAGCGCCGAAGTGCGGCACGGCCCGATGGAG
CTGATCGAGCGCGACTACCCGCTGCTCGTGTTCGCGCCGCCCGGGCCCGAGCAGGAGAGCCTGCTGCAGCTCGCGCGCGA
CATGCGCGCGCGCGGCGCGCGCGTGCTGCTCGCCGCGCCGGCGGGTACGCCCGATGCGACGCTGCCGCTCGCGCGCACCG
CGCACGCGGCGCTCGATCCGATCGCCGCGATCCTCACGTTCTACGTGATGGCGGCCGGGCTCGCGCCCGCGCGCGGCCGC
GATCCCGATGCGCCGCGCCATCTGCACAAGATCACCGAAACACACTGA

Upstream 100 bases:

>100_bases
CGCGGCCGCATCGCGCGTGGCGCGTGGGCCGATCTCGCCGTGTTCGACCGCGAGCTGAATCTGACCGCAACCTTCGTCGA
AGGAGAATCGATTGTCGAAT

Downstream 100 bases:

>100_bases
CGATCCGACGATCACCGACGAGACGAGACAGCCATGAGACGTGCCGAGGAGTCACAGTTGAAGCAACAAGCATCCCACGA
CCAGATCGTGCTGGTCGCTC

Product: SIS domain-containing protein

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MLNEARESARVVAAQLADTRRVEALAQHLATHAPQVALTVARGSSDHAASYFASLTMSRLGVPVASLPMSVATLQQAPLK
VRGQLALAFSQSGKSPDLVNTMAALREAGALTVAAVNVLPSPLAHACEHPLPLLAGPELSVAATKSYIAMLSIAAQLVAF
WQRDAALASALRGLPDALEQAGRLDWSSAVDELRDVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
LIERDYPLLVFAPPGPEQESLLQLARDMRARGARVLLAAPAGTPDATLPLARTAHAALDPIAAILTFYVMAAGLAPARGR
DPDAPRHLHKITETH

Sequences:

>Translated_335_residues
MLNEARESARVVAAQLADTRRVEALAQHLATHAPQVALTVARGSSDHAASYFASLTMSRLGVPVASLPMSVATLQQAPLK
VRGQLALAFSQSGKSPDLVNTMAALREAGALTVAAVNVLPSPLAHACEHPLPLLAGPELSVAATKSYIAMLSIAAQLVAF
WQRDAALASALRGLPDALEQAGRLDWSSAVDELRDVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
LIERDYPLLVFAPPGPEQESLLQLARDMRARGARVLLAAPAGTPDATLPLARTAHAALDPIAAILTFYVMAAGLAPARGR
DPDAPRHLHKITETH
>Mature_335_residues
MLNEARESARVVAAQLADTRRVEALAQHLATHAPQVALTVARGSSDHAASYFASLTMSRLGVPVASLPMSVATLQQAPLK
VRGQLALAFSQSGKSPDLVNTMAALREAGALTVAAVNVLPSPLAHACEHPLPLLAGPELSVAATKSYIAMLSIAAQLVAF
WQRDAALASALRGLPDALEQAGRLDWSSAVDELRDVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
LIERDYPLLVFAPPGPEQESLLQLARDMRARGARVLLAAPAGTPDATLPLARTAHAALDPIAAILTFYVMAAGLAPARGR
DPDAPRHLHKITETH

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=265, Percent_Identity=26.7924528301887, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI205277386, Length=264, Percent_Identity=25.3787878787879, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI1790167, Length=271, Percent_Identity=33.210332103321, Blast_Score=108, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17532899, Length=315, Percent_Identity=26.031746031746, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17532897, Length=316, Percent_Identity=26.2658227848101, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17539970, Length=315, Percent_Identity=26.3492063492064, Blast_Score=98, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6322745, Length=309, Percent_Identity=25.8899676375405, Blast_Score=96, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6323731, Length=205, Percent_Identity=23.9024390243902, Blast_Score=66, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21357745, Length=309, Percent_Identity=24.2718446601942, Blast_Score=101, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 35257; Mature: 35257

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNEARESARVVAAQLADTRRVEALAQHLATHAPQVALTVARGSSDHAASYFASLTMSRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHH
GVPVASLPMSVATLQQAPLKVRGQLALAFSQSGKSPDLVNTMAALREAGALTVAAVNVLP
CCCHHHHHHHHHHHHHCCHHHHHHEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHCC
SPLAHACEHPLPLLAGPELSVAATKSYIAMLSIAAQLVAFWQRDAALASALRGLPDALEQ
CHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
AGRLDWSSAVDELRDVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
HCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHCCCHHH
LIERDYPLLVFAPPGPEQESLLQLARDMRARGARVLLAAPAGTPDATLPLARTAHAALDP
HHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHH
IAAILTFYVMAAGLAPARGRDPDAPRHLHKITETH
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MLNEARESARVVAAQLADTRRVEALAQHLATHAPQVALTVARGSSDHAASYFASLTMSRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHH
GVPVASLPMSVATLQQAPLKVRGQLALAFSQSGKSPDLVNTMAALREAGALTVAAVNVLP
CCCHHHHHHHHHHHHHCCHHHHHHEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHCC
SPLAHACEHPLPLLAGPELSVAATKSYIAMLSIAAQLVAFWQRDAALASALRGLPDALEQ
CHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
AGRLDWSSAVDELRDVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
HCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHCCCHHH
LIERDYPLLVFAPPGPEQESLLQLARDMRARGARVLLAAPAGTPDATLPLARTAHAALDP
HHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHH
IAAILTFYVMAAGLAPARGRDPDAPRHLHKITETH
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]