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The map label for this gene is mco [H]

Identifier: 126453660

GI number: 126453660

Start: 941558

End: 943168

Strand: Direct

Name: mco [H]

Synonym: BURPS1106A_0961

Alternate gene names: 126453660

Gene position: 941558-943168 (Clockwise)

Preceding gene: 126453346

Following gene: 126455350

Centisome position: 23.61

GC content: 70.95

Gene sequence:

>1611_bases
ATGTTGCGCAGACATTTCCTTTCGAGCGCGCTGGCGGCGGCCGCCGCGTCGCTTTTCGCGCGCGGCGCGTTTGCCGCAGG
CCAAGCGATGGACGGCATGCAGGGCATGGAAGGCATGGACGACATGCCGGACATGAAGCCCGCGCCGGCTCACGCGCGGC
ACGGCAAGCCGGCGCCCACGCCCGCTTCCGCGCTGGCCGCCGCCGACGCGCTGCCGGCGGGCGCGCCGCTTGCCGCGTTG
CGCGTGCTTGCAAACGAGAGCCGCGAGCCGGGCGTATTTCGCGCGACGCTCGTTGCGCAGCCCGTCGCGCGCGCGCTCCT
GCCGGGCGCCGCGCCGACGACGCTCTGGCAGTTCGGCGCCGGCACGCAAGGGCCCGCGGTCGGCCCGCTCATCGACGTGC
GCGAAGGCGATGCGGTCGAGATCCGCTTCGTGAACCGGCTGCCGCAGCCGTCGACGATCCACTGGCACGGATTGCCGGTG
CCGCCCGATCAGGATGGCAATCCGTCCGATCTCGTCGCGCCGGGTGCGACGCGCGTCTATCGTTTCACACTGCCGAAAGG
CAGCGCGGGCACGTACTGGTATCACCCGCATCCGCACATGGCGACGGCCGAGCAGGTGTTTCGCGGGCTCGCCGGCCCGA
TCGTCGTGCGCGCGGCCGACGATCCGCTCGCCGGCTGGCCCGAGCGGCATCTGTTCGTGTCCGATCTGAAGCTCGCGCGC
GACGGCGCGATCGCGCCGAACGACATGATGGATTGGATGAACGGTCGCCAAGGTCAGTTCGCGCTCGTCAACGGTGCGCG
ACGGCCGCGCATTTCGCTCACCGGCGACGAACGCTGGCGCGTATGGAACGGGTGCAGCGCGCGCTACTTGCGCATCGCGT
TCGACGACGGAAGGCCGTTTGCGCACGTCGGCACGGACGGCGGGCTGTTCGACGCGCCGCGCGAGGTGGCCTCGCTGTTG
CTCGCGCCGGGCGAGCGCGCCGAGCTCGTCGTGCGCGCGGGCGACCGTGCGTCGCACGCGGTGCTGACCGCGCTCGAGTA
CGATCGCGGCAAGATGGCGATGGCGATGTCGGAGGCGGCGCACGGCAGCCTGCCGCCCGATCCCGCGCTGCCGCTCGCCG
ACGTCGCATTCGAGCCGGCCGCGCCGCGCGCGTTGCCCGCCCGGCTGCGCGCGGTGCCCGCGCTCGGCGAGCCGGTCGCG
CGCAAGGAGGTCGTGTTCGGCGAGCAGATGGACATGGCCGCGATGATGCGCGCGGGCGCGCATGGTCGACCGGCCGGCAT
GCGCTTCATGGTGAACGGCGCGACGTTCGAGCCGCATCGCGCGACGCTGACGAGCCGGCGCGGCGAGATCGAATCATGGA
CGATTCGCAACGAAACCGACATGGATCACCCGTTTCATCTGCACGGCACGCAATTCCAGGTCGTCGAGCGCGAGATCGAC
GGCGAGACGACGCCCGAGCCCTATCGCGCGTGGCGCGACACGGTGAACGTTCGGAAGGGCGAGCGCGTGCGGATTCTCAC
GACGCAGACCGAGCGCGGCGAGCGGATGTTCCACTGCCACATTCTCGAGCACGAGGATCTCGGGATGATGGGGACGCTGA
AAGTCGTTTGA

Upstream 100 bases:

>100_bases
TGGTGCCGCGCGTGCGCGCGTTGTCCGCACGCGAAGTGCAGCGTGCGCGCCGACTGGTGTATTGTCGGAACCTCCGCTTC
GACAACACGGGAATCGATCG

Downstream 100 bases:

>100_bases
AATACGCGGCGAACGCGTTGAGTCACCGAGCGCACACTCGGTTCGCGCAACGGCGTTCGAGCGCACGGCGCGCGCGCGAA
AAAAAACCCGGCTGGAAGCC

Product: multicopper oxidase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 536; Mature: 536

Protein sequence:

>536_residues
MLRRHFLSSALAAAAASLFARGAFAAGQAMDGMQGMEGMDDMPDMKPAPAHARHGKPAPTPASALAAADALPAGAPLAAL
RVLANESREPGVFRATLVAQPVARALLPGAAPTTLWQFGAGTQGPAVGPLIDVREGDAVEIRFVNRLPQPSTIHWHGLPV
PPDQDGNPSDLVAPGATRVYRFTLPKGSAGTYWYHPHPHMATAEQVFRGLAGPIVVRAADDPLAGWPERHLFVSDLKLAR
DGAIAPNDMMDWMNGRQGQFALVNGARRPRISLTGDERWRVWNGCSARYLRIAFDDGRPFAHVGTDGGLFDAPREVASLL
LAPGERAELVVRAGDRASHAVLTALEYDRGKMAMAMSEAAHGSLPPDPALPLADVAFEPAAPRALPARLRAVPALGEPVA
RKEVVFGEQMDMAAMMRAGAHGRPAGMRFMVNGATFEPHRATLTSRRGEIESWTIRNETDMDHPFHLHGTQFQVVEREID
GETTPEPYRAWRDTVNVRKGERVRILTTQTERGERMFHCHILEHEDLGMMGTLKVV

Sequences:

>Translated_536_residues
MLRRHFLSSALAAAAASLFARGAFAAGQAMDGMQGMEGMDDMPDMKPAPAHARHGKPAPTPASALAAADALPAGAPLAAL
RVLANESREPGVFRATLVAQPVARALLPGAAPTTLWQFGAGTQGPAVGPLIDVREGDAVEIRFVNRLPQPSTIHWHGLPV
PPDQDGNPSDLVAPGATRVYRFTLPKGSAGTYWYHPHPHMATAEQVFRGLAGPIVVRAADDPLAGWPERHLFVSDLKLAR
DGAIAPNDMMDWMNGRQGQFALVNGARRPRISLTGDERWRVWNGCSARYLRIAFDDGRPFAHVGTDGGLFDAPREVASLL
LAPGERAELVVRAGDRASHAVLTALEYDRGKMAMAMSEAAHGSLPPDPALPLADVAFEPAAPRALPARLRAVPALGEPVA
RKEVVFGEQMDMAAMMRAGAHGRPAGMRFMVNGATFEPHRATLTSRRGEIESWTIRNETDMDHPFHLHGTQFQVVEREID
GETTPEPYRAWRDTVNVRKGERVRILTTQTERGERMFHCHILEHEDLGMMGTLKVV
>Mature_536_residues
MLRRHFLSSALAAAAASLFARGAFAAGQAMDGMQGMEGMDDMPDMKPAPAHARHGKPAPTPASALAAADALPAGAPLAAL
RVLANESREPGVFRATLVAQPVARALLPGAAPTTLWQFGAGTQGPAVGPLIDVREGDAVEIRFVNRLPQPSTIHWHGLPV
PPDQDGNPSDLVAPGATRVYRFTLPKGSAGTYWYHPHPHMATAEQVFRGLAGPIVVRAADDPLAGWPERHLFVSDLKLAR
DGAIAPNDMMDWMNGRQGQFALVNGARRPRISLTGDERWRVWNGCSARYLRIAFDDGRPFAHVGTDGGLFDAPREVASLL
LAPGERAELVVRAGDRASHAVLTALEYDRGKMAMAMSEAAHGSLPPDPALPLADVAFEPAAPRALPARLRAVPALGEPVA
RKEVVFGEQMDMAAMMRAGAHGRPAGMRFMVNGATFEPHRATLTSRRGEIESWTIRNETDMDHPFHLHGTQFQVVEREID
GETTPEPYRAWRDTVNVRKGERVRILTTQTERGERMFHCHILEHEDLGMMGTLKVV

Specific function: May be involved in copper homeostasis and oxidative stress response [H]

COG id: COG2132

COG function: function code Q; Putative multicopper oxidases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multicopper oxidase family [H]

Homologues:

Organism=Escherichia coli, GI1786314, Length=472, Percent_Identity=32.2033898305085, Blast_Score=195, Evalue=6e-51,
Organism=Escherichia coli, GI1789394, Length=441, Percent_Identity=28.3446712018141, Blast_Score=130, Evalue=3e-31,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011706
- InterPro:   IPR011707
- InterPro:   IPR002355
- InterPro:   IPR008972 [H]

Pfam domain/function: PF07731 Cu-oxidase_2; PF07732 Cu-oxidase_3 [H]

EC number: NA

Molecular weight: Translated: 58046; Mature: 58046

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS00080 MULTICOPPER_OXIDASE2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRRHFLSSALAAAAASLFARGAFAAGQAMDGMQGMEGMDDMPDMKPAPAHARHGKPAPT
CCHHHHHHHHHHHHHHHHHHHCCHHCCHHHCCHHCCCCCCCCCCCCCCCCCCCCCCCCCC
PASALAAADALPAGAPLAALRVLANESREPGVFRATLVAQPVARALLPGAAPTTLWQFGA
CHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHCCCCCCHHHHCCCC
GTQGPAVGPLIDVREGDAVEIRFVNRLPQPSTIHWHGLPVPPDQDGNPSDLVAPGATRVY
CCCCCCCCCEEECCCCCEEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCEECCCCCEEE
RFTLPKGSAGTYWYHPHPHMATAEQVFRGLAGPIVVRAADDPLAGWPERHLFVSDLKLAR
EEECCCCCCCCEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEHHHHHHHC
DGAIAPNDMMDWMNGRQGQFALVNGARRPRISLTGDERWRVWNGCSARYLRIAFDDGRPF
CCCCCCHHHHHHHCCCCCCEEEECCCCCCEEEECCCCCEEEECCCCCEEEEEEEECCCCE
AHVGTDGGLFDAPREVASLLLAPGERAELVVRAGDRASHAVLTALEYDRGKMAMAMSEAA
EEECCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEECCCCCEEEHHHHHH
HGSLPPDPALPLADVAFEPAAPRALPARLRAVPALGEPVARKEVVFGEQMDMAAMMRAGA
CCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHCCC
HGRPAGMRFMVNGATFEPHRATLTSRRGEIESWTIRNETDMDHPFHLHGTQFQVVEREID
CCCCCCEEEEEECCCCCCHHHHHHHCCCCCCEEEECCCCCCCCCEEECCCEEEEEEHHCC
GETTPEPYRAWRDTVNVRKGERVRILTTQTERGERMFHCHILEHEDLGMMGTLKVV
CCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCCCCEEEEEC
>Mature Secondary Structure
MLRRHFLSSALAAAAASLFARGAFAAGQAMDGMQGMEGMDDMPDMKPAPAHARHGKPAPT
CCHHHHHHHHHHHHHHHHHHHCCHHCCHHHCCHHCCCCCCCCCCCCCCCCCCCCCCCCCC
PASALAAADALPAGAPLAALRVLANESREPGVFRATLVAQPVARALLPGAAPTTLWQFGA
CHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHCCCCCCHHHHCCCC
GTQGPAVGPLIDVREGDAVEIRFVNRLPQPSTIHWHGLPVPPDQDGNPSDLVAPGATRVY
CCCCCCCCCEEECCCCCEEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCEECCCCCEEE
RFTLPKGSAGTYWYHPHPHMATAEQVFRGLAGPIVVRAADDPLAGWPERHLFVSDLKLAR
EEECCCCCCCCEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEHHHHHHHC
DGAIAPNDMMDWMNGRQGQFALVNGARRPRISLTGDERWRVWNGCSARYLRIAFDDGRPF
CCCCCCHHHHHHHCCCCCCEEEECCCCCCEEEECCCCCEEEECCCCCEEEEEEEECCCCE
AHVGTDGGLFDAPREVASLLLAPGERAELVVRAGDRASHAVLTALEYDRGKMAMAMSEAA
EEECCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEECCCCCEEEHHHHHH
HGSLPPDPALPLADVAFEPAAPRALPARLRAVPALGEPVARKEVVFGEQMDMAAMMRAGA
CCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHCCC
HGRPAGMRFMVNGATFEPHRATLTSRRGEIESWTIRNETDMDHPFHLHGTQFQVVEREID
CCCCCCEEEEEECCCCCCHHHHHHHCCCCCCEEEECCCCCCCCCEEECCCEEEEEEHHCC
GETTPEPYRAWRDTVNVRKGERVRILTTQTERGERMFHCHILEHEDLGMMGTLKVV
CCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA