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The map label for this gene is paaG [C]

Identifier: 126453469

GI number: 126453469

Start: 404802

End: 405629

Strand: Direct

Name: paaG [C]

Synonym: BURPS1106A_0439

Alternate gene names: 126453469

Gene position: 404802-405629 (Clockwise)

Preceding gene: 126454589

Following gene: 126453407

Centisome position: 10.15

GC content: 70.41

Gene sequence:

>828_bases
ATGACCGATCTCGCTCTCTATGCCGGCTATGAAGCGCTGCGCATCCAGCGCCGGCCGCACGGCATCGTCGAAATCGTGAT
GAGCGGCGAAGGCGCGAACCGCAGCGGCCTCGCGGTCGCGAGCGAGGCGATGCACCGCGAGCTCGCCGATATCTGGCGCG
ACGTCGACCGCGATCCCGACGCGCGCGTCGCGGTGATCCGCGGCGAAGGCAAGGGCTTCTCGGCGGGCGGCGATCTCGCG
CTCGTCGAGCGCATGGCCGACGCTCACGCGGTGCGCGAGCGCGTCTGGCGCGAAGCGCGCGATCTCGTCTACAACGTGAT
CAATTGCAGCAAGCCGATCGTGTCGGCGATGCACGGGCCGGCCGTCGGCGCCGGGCTCGTCGCCGGGCTGCTCGCCGACG
TGTCGATCGCCGCGAAGCACGCGCGGATCATCGACGGGCACACGCGTCTCGGCGTCGCCGCGGGCGATCACGCGGCGATC
GTCTGGCCGCTGCTCTGCGGGATGGCGAAGGCGAAATACCACCTGCTCCTCTGCGAGCCCGTGAGCGGCGAGGAGGCCGA
GCGCATCGGGCTCGTGTCGCTCGCGCTCGACGATCACGAGCTGCTGCCGAAGGCGTACGAGATCGCCGAGCGCCTCGCGC
AAGGCTCGCAAAGCGCGATCCGCTGGACCAAGTACGCGCTCAACAACTGGCTGCGGCTGGCCGGGCCGACCTTCGACGCG
TCGCTCGCGCTCGAATTCATGGGTTTTTCCGGGCCGGACGTGCGCGAAGGCATTCGCTCGCTGCGCGAGCGCCGCGCGCC
GGATTTCACGGGCGGCGCGCCGTCTTGA

Upstream 100 bases:

>100_bases
GCGCCGGGTTTCGCCGGATGACCCTGCCGCCCGCCTTCGCTACACTGAGTTTGCAGGCTTGTCGGCTCACCCCACACCCC
ACTTCGAAGGAAGGTCCAGC

Downstream 100 bases:

>100_bases
GCGCCGCGCGCGCTATGATCGATCATGAACGCCGCCGCGCGTGCGGCGTATCCCCACGACCTGCGTGACTCGCTTCGAAG
GAATCGACGATGACCGACCC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MTDLALYAGYEALRIQRRPHGIVEIVMSGEGANRSGLAVASEAMHRELADIWRDVDRDPDARVAVIRGEGKGFSAGGDLA
LVERMADAHAVRERVWREARDLVYNVINCSKPIVSAMHGPAVGAGLVAGLLADVSIAAKHARIIDGHTRLGVAAGDHAAI
VWPLLCGMAKAKYHLLLCEPVSGEEAERIGLVSLALDDHELLPKAYEIAERLAQGSQSAIRWTKYALNNWLRLAGPTFDA
SLALEFMGFSGPDVREGIRSLRERRAPDFTGGAPS

Sequences:

>Translated_275_residues
MTDLALYAGYEALRIQRRPHGIVEIVMSGEGANRSGLAVASEAMHRELADIWRDVDRDPDARVAVIRGEGKGFSAGGDLA
LVERMADAHAVRERVWREARDLVYNVINCSKPIVSAMHGPAVGAGLVAGLLADVSIAAKHARIIDGHTRLGVAAGDHAAI
VWPLLCGMAKAKYHLLLCEPVSGEEAERIGLVSLALDDHELLPKAYEIAERLAQGSQSAIRWTKYALNNWLRLAGPTFDA
SLALEFMGFSGPDVREGIRSLRERRAPDFTGGAPS
>Mature_274_residues
TDLALYAGYEALRIQRRPHGIVEIVMSGEGANRSGLAVASEAMHRELADIWRDVDRDPDARVAVIRGEGKGFSAGGDLAL
VERMADAHAVRERVWREARDLVYNVINCSKPIVSAMHGPAVGAGLVAGLLADVSIAAKHARIIDGHTRLGVAAGDHAAIV
WPLLCGMAKAKYHLLLCEPVSGEEAERIGLVSLALDDHELLPKAYEIAERLAQGSQSAIRWTKYALNNWLRLAGPTFDAS
LALEFMGFSGPDVREGIRSLRERRAPDFTGGAPS

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=226, Percent_Identity=22.1238938053097, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787660, Length=237, Percent_Identity=30.8016877637131, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787659, Length=238, Percent_Identity=29.4117647058824, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788597, Length=270, Percent_Identity=24.8148148148148, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI221142681, Length=211, Percent_Identity=27.4881516587678, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=243, Percent_Identity=26.7489711934156, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17534483, Length=194, Percent_Identity=31.4432989690722, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17535521, Length=179, Percent_Identity=27.3743016759777, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560910, Length=200, Percent_Identity=27, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=232, Percent_Identity=25, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17540306, Length=260, Percent_Identity=25, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24654903, Length=195, Percent_Identity=25.6410256410256, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24653139, Length=240, Percent_Identity=26.25, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI20129971, Length=267, Percent_Identity=23.5955056179775, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24653477, Length=267, Percent_Identity=23.5955056179775, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 29660; Mature: 29529

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLALYAGYEALRIQRRPHGIVEIVMSGEGANRSGLAVASEAMHRELADIWRDVDRDPD
CCCCHHHCCHHHHHEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
ARVAVIRGEGKGFSAGGDLALVERMADAHAVRERVWREARDLVYNVINCSKPIVSAMHGP
CEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC
AVGAGLVAGLLADVSIAAKHARIIDGHTRLGVAAGDHAAIVWPLLCGMAKAKYHLLLCEP
CHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCHHHHHHHHHHHHHCCEEEEEECC
VSGEEAERIGLVSLALDDHELLPKAYEIAERLAQGSQSAIRWTKYALNNWLRLAGPTFDA
CCCCCHHHEEEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCH
SLALEFMGFSGPDVREGIRSLRERRAPDFTGGAPS
HHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TDLALYAGYEALRIQRRPHGIVEIVMSGEGANRSGLAVASEAMHRELADIWRDVDRDPD
CCCHHHCCHHHHHEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
ARVAVIRGEGKGFSAGGDLALVERMADAHAVRERVWREARDLVYNVINCSKPIVSAMHGP
CEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC
AVGAGLVAGLLADVSIAAKHARIIDGHTRLGVAAGDHAAIVWPLLCGMAKAKYHLLLCEP
CHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCHHHHHHHHHHHHHCCEEEEEECC
VSGEEAERIGLVSLALDDHELLPKAYEIAERLAQGSQSAIRWTKYALNNWLRLAGPTFDA
CCCCCHHHEEEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCH
SLALEFMGFSGPDVREGIRSLRERRAPDFTGGAPS
HHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA