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The map label for this gene is ttdR [H]

Identifier: 126453397

GI number: 126453397

Start: 746914

End: 747738

Strand: Direct

Name: ttdR [H]

Synonym: BURPS1106A_0764

Alternate gene names: 126453397

Gene position: 746914-747738 (Clockwise)

Preceding gene: 126452655

Following gene: 126453956

Centisome position: 18.73

GC content: 74.06

Gene sequence:

>825_bases
GTGAACGGCTCGCCGAGGCCGGGGGCGACGCGCCCGACGAGCACGCCCGCGACGAGCGAGGGCGAGACCTACCTGGGCTA
CGCGACGCGCATCGTCGCCGACATCCGGCGGATGGCGGACGCGGTGCGCGCGAGCCGCTCGGTGCCGCGCGGGCTGTTGC
GCGTGAACGTGATGCTCGGCTTCGGGCGCACGACGATCACGCCGCTCGTCTCCGAGTTCGCGACGCCGCATCCGCGGGTG
GAAGTGCGGCTCGACGTGACGGACCGGCCGGTCGATCGCGTCGACGGCGGCTTCGATTTCGCGATCCGCTTCGGCGAGCC
GCCGGATACGCGGCTCAACGCGCGCCGCATCATGTCGAACCGGCGCCTGCTGCGCGCGTCGCCCGTGCATCTGCAGCGGC
GCGGCGCGCCCGCGAGCCTCGCTCGCTGCATCGTCCATCGGCGAAACGACGACGCGCACGGTGTGTGGCGCTTCGTGCGC
GACGGCGAGGCCGAGGGCGTGAAGGTGCGCGCCGCGCCGTCGAGCAACGACGGCGACATCGTGCCCGGCTGGGCGCTCGA
CGGCCACGGCATCCTGATCCGCTCGGAATGGGATCTCGCGAAGTATCTGGAGAGCGGGCGCCTGAGGCGCGTGCTGCCCG
AGTACGCGCTGCCTTCGGCGGATCTGTCCGCCTGCTATCCGGTGCGGCGCAACCCGTCGGCGCGAGCCCGCGCGCCGATC
GATTTTCTCGTCGCGCGGCTCGGCGCATCCGCGCCGGCGCCGGCGCGGACACCGGAGGGCGGCCGACGGGCGGGCTCGCG
GGACGTGCCGCCGCGCGTGAGATAA

Upstream 100 bases:

>100_bases
CCGCGTGAATCTCGTTCATCCGCGCGATGCCGACGACGAGCGACGCGAACACGGACGGCGCGAGCCGCATCCGGATCAGG
CGGACGGGGCGCCGAGCGGC

Downstream 100 bases:

>100_bases
TCGCGCTTTCACCCGCCAGCGATGATGCGGCCCCGCCGCACCCGATACGTTGAACCTCCAGCCCGCTTCCCTCGCCCAGA
TCGACGATTTCGACGAGATC

Product: LysR substrate binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MNGSPRPGATRPTSTPATSEGETYLGYATRIVADIRRMADAVRASRSVPRGLLRVNVMLGFGRTTITPLVSEFATPHPRV
EVRLDVTDRPVDRVDGGFDFAIRFGEPPDTRLNARRIMSNRRLLRASPVHLQRRGAPASLARCIVHRRNDDAHGVWRFVR
DGEAEGVKVRAAPSSNDGDIVPGWALDGHGILIRSEWDLAKYLESGRLRRVLPEYALPSADLSACYPVRRNPSARARAPI
DFLVARLGASAPAPARTPEGGRRAGSRDVPPRVR

Sequences:

>Translated_274_residues
MNGSPRPGATRPTSTPATSEGETYLGYATRIVADIRRMADAVRASRSVPRGLLRVNVMLGFGRTTITPLVSEFATPHPRV
EVRLDVTDRPVDRVDGGFDFAIRFGEPPDTRLNARRIMSNRRLLRASPVHLQRRGAPASLARCIVHRRNDDAHGVWRFVR
DGEAEGVKVRAAPSSNDGDIVPGWALDGHGILIRSEWDLAKYLESGRLRRVLPEYALPSADLSACYPVRRNPSARARAPI
DFLVARLGASAPAPARTPEGGRRAGSRDVPPRVR
>Mature_274_residues
MNGSPRPGATRPTSTPATSEGETYLGYATRIVADIRRMADAVRASRSVPRGLLRVNVMLGFGRTTITPLVSEFATPHPRV
EVRLDVTDRPVDRVDGGFDFAIRFGEPPDTRLNARRIMSNRRLLRASPVHLQRRGAPASLARCIVHRRNDDAHGVWRFVR
DGEAEGVKVRAAPSSNDGDIVPGWALDGHGILIRSEWDLAKYLESGRLRRVLPEYALPSADLSACYPVRRNPSARARAPI
DFLVARLGASAPAPARTPEGGRRAGSRDVPPRVR

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=243, Percent_Identity=37.8600823045267, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI87081978, Length=240, Percent_Identity=38.75, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1786401, Length=236, Percent_Identity=30.9322033898305, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI145693193, Length=232, Percent_Identity=28.8793103448276, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787589, Length=244, Percent_Identity=25.8196721311475, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 30072; Mature: 30072

Theoretical pI: Translated: 11.80; Mature: 11.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGSPRPGATRPTSTPATSEGETYLGYATRIVADIRRMADAVRASRSVPRGLLRVNVMLG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEEEEE
FGRTTITPLVSEFATPHPRVEVRLDVTDRPVDRVDGGFDFAIRFGEPPDTRLNARRIMSN
CCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHCCCEEEEEEECCCCCCHHHHHHHHHC
RRLLRASPVHLQRRGAPASLARCIVHRRNDDAHGVWRFVRDGEAEGVKVRAAPSSNDGDI
CCEEECCCCHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCC
VPGWALDGHGILIRSEWDLAKYLESGRLRRVLPEYALPSADLSACYPVRRNPSARARAPI
CCCEEECCCEEEEECCCHHHHHHHCCCHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCH
DFLVARLGASAPAPARTPEGGRRAGSRDVPPRVR
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNGSPRPGATRPTSTPATSEGETYLGYATRIVADIRRMADAVRASRSVPRGLLRVNVMLG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEEEEE
FGRTTITPLVSEFATPHPRVEVRLDVTDRPVDRVDGGFDFAIRFGEPPDTRLNARRIMSN
CCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHCCCEEEEEEECCCCCCHHHHHHHHHC
RRLLRASPVHLQRRGAPASLARCIVHRRNDDAHGVWRFVRDGEAEGVKVRAAPSSNDGDI
CCEEECCCCHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCC
VPGWALDGHGILIRSEWDLAKYLESGRLRRVLPEYALPSADLSACYPVRRNPSARARAPI
CCCEEECCCEEEEECCCHHHHHHHCCCHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCH
DFLVARLGASAPAPARTPEGGRRAGSRDVPPRVR
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]