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The map label for this gene is selU [H]

Identifier: 126453956

GI number: 126453956

Start: 747788

End: 748867

Strand: Direct

Name: selU [H]

Synonym: BURPS1106A_0765

Alternate gene names: 126453956

Gene position: 747788-748867 (Clockwise)

Preceding gene: 126453397

Following gene: 126451644

Centisome position: 18.75

GC content: 69.35

Gene sequence:

>1080_bases
TTGAACCTCCAGCCCGCTTCCCTCGCCCAGATCGACGATTTCGACGAGATCGTCGACGTCCGCACGCCGCTCGAATACGC
GGAGGACCATATTCCGGGCGCGCTGAACGCGCCGGTTCTCAGCAACGAAGAGCGCGTGATCGTCGGCACGATGTACAAGC
AGGTGTCGCCGTTCGAGGCGACCCGCGTCGGTGCGGCGATGGTCGCGCGCAACATCGCCGCGCATCTGGACACGACGTTC
GCCGATCGCCCGCGCAACTGGCGCCCGCTCATCTATTGCTGGCGCGGCGGCAAGCGCTCCGGTTCGATGACGGTCTGGTT
CAACATGATCGGCTGGCGCGCGCGGCAGCTCGACGGCGGCTACAAGACGTACCGCCGCTCGATCGTCGACGCGCTCGGCG
AACTGCCCGCCGGGTTCCGTTACGTCGTGCTCGCCGGACATACGGGCAGCGGCAAGACGCGGCTGCTGCACGCGCTTGCG
CGGGCAGGCGCGCAGACGCTCGATCTCGAGGCGCTCGCCGCGCATCGCGGCTCGTTGCTGGGCGCGCTGCCGAGCGGCGA
GCAGCCTTCGCAGAAGGCGTTCGACACGGCGCTCGTCAGCGCGCTGCGCGGCTTCGAGCACGACCGGCCCGTGTTCATCG
AAGCGGAGAGCCGGCGCATCGGCGCGATCACGCTGCCGCTCGCGCTGCTCGCCGGCATGCACGCGGCGGATTGCGTGAAG
GTGGAGACCGCGCGCGACGAGCGCGTCGAGCTGTTGTTGCAGGACTATGGGCATCTGTTCGATCAGCCCGCGTTCTTCAA
GATCCAGCTCGAGAAGCTCGTGCCGCTGCACGGGCACGCGCGGATCCGCAAGTGGCACGCGATGCTCGACGAAGGGCGGC
GCGGCGAGCTGTTCGAGGAGCTCGTCGACGTGCACTACGATCCCGCCTATACGCGCAGCAGCGGCGCGCACTTCGCGCGC
CTGCCGCAGGCGGAGCGCTTTGCGTTCCGGCCGACCGCGCGCGATGTCGTCGAGCAGGCGCGGGCATTGCTTGCGCATCT
CGACGCAGCGGGCGCGCGTGCGCTCGACAAGCGGGCCTGA

Upstream 100 bases:

>100_bases
GAGGGCGGCCGACGGGCGGGCTCGCGGGACGTGCCGCCGCGCGTGAGATAATCGCGCTTTCACCCGCCAGCGATGATGCG
GCCCCGCCGCACCCGATACG

Downstream 100 bases:

>100_bases
ACGATACGTCGCGATCGCGCGGGTTCATCCGGCCGCGACCGGCGAACCGGTCGCCGTCGCGCTTGCCGTACGTCGCATCG
CGCCGCTTCGGGCGTGCCTT

Product: tRNA 2-selenouridine synthase

Products: NA

Alternate protein names: Selenophosphate-dependent tRNA 2-selenouridine synthase [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MNLQPASLAQIDDFDEIVDVRTPLEYAEDHIPGALNAPVLSNEERVIVGTMYKQVSPFEATRVGAAMVARNIAAHLDTTF
ADRPRNWRPLIYCWRGGKRSGSMTVWFNMIGWRARQLDGGYKTYRRSIVDALGELPAGFRYVVLAGHTGSGKTRLLHALA
RAGAQTLDLEALAAHRGSLLGALPSGEQPSQKAFDTALVSALRGFEHDRPVFIEAESRRIGAITLPLALLAGMHAADCVK
VETARDERVELLLQDYGHLFDQPAFFKIQLEKLVPLHGHARIRKWHAMLDEGRRGELFEELVDVHYDPAYTRSSGAHFAR
LPQAERFAFRPTARDVVEQARALLAHLDAAGARALDKRA

Sequences:

>Translated_359_residues
MNLQPASLAQIDDFDEIVDVRTPLEYAEDHIPGALNAPVLSNEERVIVGTMYKQVSPFEATRVGAAMVARNIAAHLDTTF
ADRPRNWRPLIYCWRGGKRSGSMTVWFNMIGWRARQLDGGYKTYRRSIVDALGELPAGFRYVVLAGHTGSGKTRLLHALA
RAGAQTLDLEALAAHRGSLLGALPSGEQPSQKAFDTALVSALRGFEHDRPVFIEAESRRIGAITLPLALLAGMHAADCVK
VETARDERVELLLQDYGHLFDQPAFFKIQLEKLVPLHGHARIRKWHAMLDEGRRGELFEELVDVHYDPAYTRSSGAHFAR
LPQAERFAFRPTARDVVEQARALLAHLDAAGARALDKRA
>Mature_359_residues
MNLQPASLAQIDDFDEIVDVRTPLEYAEDHIPGALNAPVLSNEERVIVGTMYKQVSPFEATRVGAAMVARNIAAHLDTTF
ADRPRNWRPLIYCWRGGKRSGSMTVWFNMIGWRARQLDGGYKTYRRSIVDALGELPAGFRYVVLAGHTGSGKTRLLHALA
RAGAQTLDLEALAAHRGSLLGALPSGEQPSQKAFDTALVSALRGFEHDRPVFIEAESRRIGAITLPLALLAGMHAADCVK
VETARDERVELLLQDYGHLFDQPAFFKIQLEKLVPLHGHARIRKWHAMLDEGRRGELFEELVDVHYDPAYTRSSGAHFAR
LPQAERFAFRPTARDVVEQARALLAHLDAAGARALDKRA

Specific function: Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA [H]

COG id: COG2603

COG function: function code R; Predicted ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Escherichia coli, GI1786712, Length=244, Percent_Identity=35.2459016393443, Blast_Score=115, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001763
- InterPro:   IPR017582 [H]

Pfam domain/function: PF00581 Rhodanese [H]

EC number: NA

Molecular weight: Translated: 39857; Mature: 39857

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLQPASLAQIDDFDEIVDVRTPLEYAEDHIPGALNAPVLSNEERVIVGTMYKQVSPFEA
CCCCCCCHHHHCCHHHHHHHCCCHHHHHHCCCCCCCCCEECCCCEEEEEEHHHHCCCHHH
TRVGAAMVARNIAAHLDTTFADRPRNWRPLIYCWRGGKRSGSMTVWFNMIGWRARQLDGG
HHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEEEECCCCCCCCEEEEEEHHCCCHHHCCCH
YKTYRRSIVDALGELPAGFRYVVLAGHTGSGKTRLLHALARAGAQTLDLEALAAHRGSLL
HHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCEE
GALPSGEQPSQKAFDTALVSALRGFEHDRPVFIEAESRRIGAITLPLALLAGMHAADCVK
ECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCHHHEEE
VETARDERVELLLQDYGHLFDQPAFFKIQLEKLVPLHGHARIRKWHAMLDEGRRGELFEE
EECCHHHHHHHHHHHHHHHHCCCCEEEEEEEHHCCCCCHHHHHHHHHHHCCCCCCHHHHH
LVDVHYDPAYTRSSGAHFARLPQAERFAFRPTARDVVEQARALLAHLDAAGARALDKRA
HHHCCCCCCCCCCCCCCHHHCCCHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLQPASLAQIDDFDEIVDVRTPLEYAEDHIPGALNAPVLSNEERVIVGTMYKQVSPFEA
CCCCCCCHHHHCCHHHHHHHCCCHHHHHHCCCCCCCCCEECCCCEEEEEEHHHHCCCHHH
TRVGAAMVARNIAAHLDTTFADRPRNWRPLIYCWRGGKRSGSMTVWFNMIGWRARQLDGG
HHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEEEECCCCCCCCEEEEEEHHCCCHHHCCCH
YKTYRRSIVDALGELPAGFRYVVLAGHTGSGKTRLLHALARAGAQTLDLEALAAHRGSLL
HHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCEE
GALPSGEQPSQKAFDTALVSALRGFEHDRPVFIEAESRRIGAITLPLALLAGMHAADCVK
ECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCHHHEEE
VETARDERVELLLQDYGHLFDQPAFFKIQLEKLVPLHGHARIRKWHAMLDEGRRGELFEE
EECCHHHHHHHHHHHHHHHHCCCCEEEEEEEHHCCCCCHHHHHHHHHHHCCCCCCHHHHH
LVDVHYDPAYTRSSGAHFARLPQAERFAFRPTARDVVEQARALLAHLDAAGARALDKRA
HHHCCCCCCCCCCCCCCHHHCCCHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]