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The map label for this gene is btuC [H]

Identifier: 126452870

GI number: 126452870

Start: 1011728

End: 1012756

Strand: Direct

Name: btuC [H]

Synonym: BURPS1106A_1036

Alternate gene names: 126452870

Gene position: 1011728-1012756 (Clockwise)

Preceding gene: 126453524

Following gene: 126451756

Centisome position: 25.37

GC content: 76.29

Gene sequence:

>1029_bases
GTGAGGTCGGACGCGCGCGGCGCCGGCATGCACGCGGCGCGCGCGGCCGCGATCTGGGCCGCGCTCGCGCTCGTCGCATG
CGCGGCGTTCGTCGCGTCGCTCACGCTCGGCAGCGTGCCCCTCACGAGCGTCGATGCGCTCGCGGCGCTCGTCCATCGCG
CGGGCGCCGATCCGCTCGCGGCCGACATCGTCCGCACGCTCAGGCTGCCGCGCGCGCTCGCGGGCTTCGGCTGCGGCGCG
CTACTCGCGCTCGCGGGCGCGCTGCTGCAGGTGCTGCTGCGGAATCCGCTCGCCGAGCCTTACGTGCTCGGCGTATCGGG
CGGCGCGGCCGCGTTCGCGCTCGTCGCGATGATCGCGGGCGGCGCGTGGTGGATCGTCGATTGCGCGTCGTTCGCCGGCG
CGCTCGCGTCGATCGCGTTCGTGCTCGGGCTCGCGCGGCGCGAGCTGTGGCGCGGCGAGCCGCGCGACGCTTCGCCGCGC
CTGCTGCTCACGGGCGTCGTGATTTCGGCCGGCTGGTTCGCGCTCATCACGCTGATGCTCGCGATCGCGCCCGACGAGCG
TCTGCGCGGCATCCTGTTCTGGCTGTCGGGCGACCTGAGCGGCGCGGCGTCGCCGGGGTTCGCGCTCGCGGCGCTCGCCG
CCGCGGCGTGCGTCGCGCTGCCGGCCGCGCCGCAACTGAACGTGCTGCTGCGCGGCGACGCGGCGGCAGCCGCGCTCGGC
GTACCGGTCGCGCGGCTGCGGCTGCGCGTCTATCTGATCGCGTCGCTCGCGGCGGCCGCGGCCGTCACGACGGCGGGCAC
GATCGGTTTCGTCGGGCTCGTCGTGCCGCACGCGCTGCGGCTCGCGTTCGGCAACGATCAGCGGATGCTGCTGCCCGCCG
CGATGCTCGCGGGCGGCGCGGGCGTGATGGCCGCGGACTTGCTCGCGCGCACGGCGATCGCGCCCGCGCAGTTGCCGGTC
GGCGTGATGACCGCGCTGATCGGCGTGCCGCTCTTCCTGTGGATGCTGTTGCGCGGGGCCGCGCGATGA

Upstream 100 bases:

>100_bases
CACGCCGCGCCGCGGCGCCTATGTCACGCTCGGCTGGCAGCAGCGCTGACGGCCGGCCGCGTCGCCGGCGCGGCGCGCGC
GGCCGCGCGCGGGAGGCCGC

Downstream 100 bases:

>100_bases
CGATGCACGACGCGCCGACCTCGCGCCCGACCCGCTACGGCACGCGGCATCTCGTGCTGAAGGCGGGCGCGCGCACGCTG
CTCGACGATTTCACGCACAC

Product: cobalamin ABC transporter, permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MRSDARGAGMHAARAAAIWAALALVACAAFVASLTLGSVPLTSVDALAALVHRAGADPLAADIVRTLRLPRALAGFGCGA
LLALAGALLQVLLRNPLAEPYVLGVSGGAAAFALVAMIAGGAWWIVDCASFAGALASIAFVLGLARRELWRGEPRDASPR
LLLTGVVISAGWFALITLMLAIAPDERLRGILFWLSGDLSGAASPGFALAALAAAACVALPAAPQLNVLLRGDAAAAALG
VPVARLRLRVYLIASLAAAAAVTTAGTIGFVGLVVPHALRLAFGNDQRMLLPAAMLAGGAGVMAADLLARTAIAPAQLPV
GVMTALIGVPLFLWMLLRGAAR

Sequences:

>Translated_342_residues
MRSDARGAGMHAARAAAIWAALALVACAAFVASLTLGSVPLTSVDALAALVHRAGADPLAADIVRTLRLPRALAGFGCGA
LLALAGALLQVLLRNPLAEPYVLGVSGGAAAFALVAMIAGGAWWIVDCASFAGALASIAFVLGLARRELWRGEPRDASPR
LLLTGVVISAGWFALITLMLAIAPDERLRGILFWLSGDLSGAASPGFALAALAAAACVALPAAPQLNVLLRGDAAAAALG
VPVARLRLRVYLIASLAAAAAVTTAGTIGFVGLVVPHALRLAFGNDQRMLLPAAMLAGGAGVMAADLLARTAIAPAQLPV
GVMTALIGVPLFLWMLLRGAAR
>Mature_342_residues
MRSDARGAGMHAARAAAIWAALALVACAAFVASLTLGSVPLTSVDALAALVHRAGADPLAADIVRTLRLPRALAGFGCGA
LLALAGALLQVLLRNPLAEPYVLGVSGGAAAFALVAMIAGGAWWIVDCASFAGALASIAFVLGLARRELWRGEPRDASPR
LLLTGVVISAGWFALITLMLAIAPDERLRGILFWLSGDLSGAASPGFALAALAAAACVALPAAPQLNVLLRGDAAAAALG
VPVARLRLRVYLIASLAAAAAVTTAGTIGFVGLVVPHALRLAFGNDQRMLLPAAMLAGGAGVMAADLLARTAIAPAQLPV
GVMTALIGVPLFLWMLLRGAAR

Specific function: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790741, Length=305, Percent_Identity=37.3770491803279, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788004, Length=287, Percent_Identity=36.9337979094077, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1790740, Length=328, Percent_Identity=35.0609756097561, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786347, Length=282, Percent_Identity=30.8510638297872, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1786805, Length=286, Percent_Identity=35.3146853146853, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786804, Length=347, Percent_Identity=34.5821325648415, Blast_Score=78, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34441; Mature: 34441

Theoretical pI: Translated: 11.48; Mature: 11.48

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSDARGAGMHAARAAAIWAALALVACAAFVASLTLGSVPLTSVDALAALVHRAGADPLA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHH
ADIVRTLRLPRALAGFGCGALLALAGALLQVLLRNPLAEPYVLGVSGGAAAFALVAMIAG
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHC
GAWWIVDCASFAGALASIAFVLGLARRELWRGEPRDASPRLLLTGVVISAGWFALITLML
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHH
AIAPDERLRGILFWLSGDLSGAASPGFALAALAAAACVALPAAPQLNVLLRGDAAAAALG
HHCCCHHHCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHC
VPVARLRLRVYLIASLAAAAAVTTAGTIGFVGLVVPHALRLAFGNDQRMLLPAAMLAGGA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
GVMAADLLARTAIAPAQLPVGVMTALIGVPLFLWMLLRGAAR
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRSDARGAGMHAARAAAIWAALALVACAAFVASLTLGSVPLTSVDALAALVHRAGADPLA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHH
ADIVRTLRLPRALAGFGCGALLALAGALLQVLLRNPLAEPYVLGVSGGAAAFALVAMIAG
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHC
GAWWIVDCASFAGALASIAFVLGLARRELWRGEPRDASPRLLLTGVVISAGWFALITLML
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHH
AIAPDERLRGILFWLSGDLSGAASPGFALAALAAAACVALPAAPQLNVLLRGDAAAAALG
HHCCCHHHCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHC
VPVARLRLRVYLIASLAAAAAVTTAGTIGFVGLVVPHALRLAFGNDQRMLLPAAMLAGGA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
GVMAADLLARTAIAPAQLPVGVMTALIGVPLFLWMLLRGAAR
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA