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The map label for this gene is btuB [H]

Identifier: 126453524

GI number: 126453524

Start: 1009619

End: 1011676

Strand: Direct

Name: btuB [H]

Synonym: BURPS1106A_1035

Alternate gene names: 126453524

Gene position: 1009619-1011676 (Clockwise)

Preceding gene: 126453449

Following gene: 126452870

Centisome position: 25.31

GC content: 68.61

Gene sequence:

>2058_bases
ATGCGAACCCCCTTCGTCCGCGCAGCGCTCGCCGCTCTGTCCGGACTGCCGTGCATCGCGCTCGCGCAAGGCGACGCGTC
GGCTTCGTCCGCTTCATTCGCGTCATCCGTCTCTTACGCGCCGGCCGCCGCTTCGCCGGCCGATGCGGATTCCGCGCTTT
CAACGGCTCCTGCAGCCGCGGCGGCATCGCCGGCGTCCGGGGCGGCGCGGGGGGCCGAGGCAGTCTCCGCAGACGCGGCA
TCCGCCGTCGCCTCCGGGGCGTCGTCGGCATCGCCGGCGCGCGCGGCGTCCGCCGCGCAGCTCGCGCCGGTCGTCGTCAC
CGCGCGGCGCGGGCCGCAGAGGCTCGCCGACGCGATTCCACAGACGACGCTCTTCGATGCGCGCGACATCGCCGACAGCG
GCGCGACCGATCTGCCCGGCCTGCTCGCGCTCGCGCCCGGCGCGCAGATCGTGCGCAACGGCGGGCCGGGCGCGAGCGCG
AGCCTTTTCCTGCGCGGCGCGCAGCCGACGCAATCGCTCGTGCTGATCGACGGCGTGCGCGTCGATTCGGCGAGCCTCGG
GCAATCGCAGATCGCCCAGTTGCCGCTCGATCAGATCGAGCGCGTCGAAGTGGTGAACGGCAACGTGTCGTCGCTGTACG
GCTCGGGCGCGATCGGCGGCGTCGTGCAGGTGTTCACGAAGAACGGCGGCAATCACCCGCCGCGCTTCGATTTTTCCGCG
GGCTACGGCAGCTATCACACGCAAACGCAAAGCGCGGGCGCATCGGGCCGACTCGATCCGGACGGCAGGACGACGTTCAG
CGTGTCGCTCGCGCGGCTGAAGACCGACGGCTTCTCGGCGCTCGATCCCGCGCGCAAGCCGCAGGCGAATCCGAACGCGA
ACGGCTATCTGAACGAGAGCGCATCCGCGTCGCTGCGGCACACGTTCAGCGACAAGTGGAACGCGGGCGTCACGTACTTC
CAGGCGAACGGCCGGAACAGCTATGACGACGCGTACGGCTCGCCGGCCGATCTGAATGATCTGTACAGCCGCGTTCAGCA
ACTGTCCGCGTTCGCGAACGGCGCGCTCGCCGACGGGTGGACGACGCGCGTGAGCGTGTCGAGCGGCAAGGATCGCAACC
AGTCGGCGCTGAACGGCGCGTACACCGATCACTTCAACACCGACAACCGCCAGTACACATGGCAGAACGATTTCGCGATC
GCGCGCGGCCACAAGATCCAGGCGGGGTACGAGCGGCTCGACCAGTCGTTCGAATCGAACAAGTATTCGGCGCCCGAGCG
GCACGTGAATTCCGGCTGGCTCGGCTATACCGGCCGCATCGGCGACAGCCGGTTCCAGGCGAACGTGCGCCGCGACCAGT
ACTCCGATTTCGGCGGCGCGAACAGCTACTATTTCGGCTATGGCTTTGACGTCACCGAGCACTGGACGGTATCGGCGAGC
TACTCGAGCGCGTTTCGCGCGCCGAGCTTCAACGATCTGTACTATCCGAACTCGGGCAACCTGTCGATCCGCCCCGAGCG
CAGCCATTCGGTCGAGGCGGCCGTGCAGTATGCGTCGGACGACGTGGGCGTCGTGCGCGTGACCGCGTTCCAGACCCGCT
ACACGAACCTGATCGACTATCGTCCCGGCGCGAGCGGCCCTTACTATGTCGCGCAGAACGTCGGCCGCGCGAAGGTGCAG
GGCGTCGAGGGATCGTGGCAGGGGCACGTCGGCGGGACCGACGTGCGCATTGCCGCGACGCTGCAGAACCCGGTCGACGA
AACCGCCGGCCGCGACCTGAACCGGCGCGCGCGGCGCTTCGCGTCGATCTCGGCGAACCGCTCGTTCGGCGGCTGGCGCG
TCGGCGGCGAATGGCTCGCGAGCGGTGCGCGCGACGATTTCGGCGATCGTCTCGGCGGATACGGCATCGTCAATCTGTCC
GCGCGCTACGACATCACGAAGTCGTGGTACGTGAGCGCGCGCATCGACAATCTGTTCGACAAGGACTACGAGCTTGCATA
CGCATACAACACGCCGCGCCGCGGCGCCTATGTCACGCTCGGCTGGCAGCAGCGCTGA

Upstream 100 bases:

>100_bases
CCCGGATACCGGCCGAGGCGGGGAGGCGGACGTGTTCGTCTCCGTGATGCGGCGCCTGCGGGGAAGCGGGCGACGCAGTG
GCTCAACAGGATCTTCGTTC

Downstream 100 bases:

>100_bases
CGGCCGGCCGCGTCGCCGGCGCGGCGCGCGCGGCCGCGCGCGGGAGGCCGCGTGAGGTCGGACGCGCGCGGCGCCGGCAT
GCACGCGGCGCGCGCGGCCG

Product: putative TonB-dependent vitamin B12 receptor BtuB

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 685; Mature: 685

Protein sequence:

>685_residues
MRTPFVRAALAALSGLPCIALAQGDASASSASFASSVSYAPAAASPADADSALSTAPAAAAASPASGAARGAEAVSADAA
SAVASGASSASPARAASAAQLAPVVVTARRGPQRLADAIPQTTLFDARDIADSGATDLPGLLALAPGAQIVRNGGPGASA
SLFLRGAQPTQSLVLIDGVRVDSASLGQSQIAQLPLDQIERVEVVNGNVSSLYGSGAIGGVVQVFTKNGGNHPPRFDFSA
GYGSYHTQTQSAGASGRLDPDGRTTFSVSLARLKTDGFSALDPARKPQANPNANGYLNESASASLRHTFSDKWNAGVTYF
QANGRNSYDDAYGSPADLNDLYSRVQQLSAFANGALADGWTTRVSVSSGKDRNQSALNGAYTDHFNTDNRQYTWQNDFAI
ARGHKIQAGYERLDQSFESNKYSAPERHVNSGWLGYTGRIGDSRFQANVRRDQYSDFGGANSYYFGYGFDVTEHWTVSAS
YSSAFRAPSFNDLYYPNSGNLSIRPERSHSVEAAVQYASDDVGVVRVTAFQTRYTNLIDYRPGASGPYYVAQNVGRAKVQ
GVEGSWQGHVGGTDVRIAATLQNPVDETAGRDLNRRARRFASISANRSFGGWRVGGEWLASGARDDFGDRLGGYGIVNLS
ARYDITKSWYVSARIDNLFDKDYELAYAYNTPRRGAYVTLGWQQR

Sequences:

>Translated_685_residues
MRTPFVRAALAALSGLPCIALAQGDASASSASFASSVSYAPAAASPADADSALSTAPAAAAASPASGAARGAEAVSADAA
SAVASGASSASPARAASAAQLAPVVVTARRGPQRLADAIPQTTLFDARDIADSGATDLPGLLALAPGAQIVRNGGPGASA
SLFLRGAQPTQSLVLIDGVRVDSASLGQSQIAQLPLDQIERVEVVNGNVSSLYGSGAIGGVVQVFTKNGGNHPPRFDFSA
GYGSYHTQTQSAGASGRLDPDGRTTFSVSLARLKTDGFSALDPARKPQANPNANGYLNESASASLRHTFSDKWNAGVTYF
QANGRNSYDDAYGSPADLNDLYSRVQQLSAFANGALADGWTTRVSVSSGKDRNQSALNGAYTDHFNTDNRQYTWQNDFAI
ARGHKIQAGYERLDQSFESNKYSAPERHVNSGWLGYTGRIGDSRFQANVRRDQYSDFGGANSYYFGYGFDVTEHWTVSAS
YSSAFRAPSFNDLYYPNSGNLSIRPERSHSVEAAVQYASDDVGVVRVTAFQTRYTNLIDYRPGASGPYYVAQNVGRAKVQ
GVEGSWQGHVGGTDVRIAATLQNPVDETAGRDLNRRARRFASISANRSFGGWRVGGEWLASGARDDFGDRLGGYGIVNLS
ARYDITKSWYVSARIDNLFDKDYELAYAYNTPRRGAYVTLGWQQR
>Mature_685_residues
MRTPFVRAALAALSGLPCIALAQGDASASSASFASSVSYAPAAASPADADSALSTAPAAAAASPASGAARGAEAVSADAA
SAVASGASSASPARAASAAQLAPVVVTARRGPQRLADAIPQTTLFDARDIADSGATDLPGLLALAPGAQIVRNGGPGASA
SLFLRGAQPTQSLVLIDGVRVDSASLGQSQIAQLPLDQIERVEVVNGNVSSLYGSGAIGGVVQVFTKNGGNHPPRFDFSA
GYGSYHTQTQSAGASGRLDPDGRTTFSVSLARLKTDGFSALDPARKPQANPNANGYLNESASASLRHTFSDKWNAGVTYF
QANGRNSYDDAYGSPADLNDLYSRVQQLSAFANGALADGWTTRVSVSSGKDRNQSALNGAYTDHFNTDNRQYTWQNDFAI
ARGHKIQAGYERLDQSFESNKYSAPERHVNSGWLGYTGRIGDSRFQANVRRDQYSDFGGANSYYFGYGFDVTEHWTVSAS
YSSAFRAPSFNDLYYPNSGNLSIRPERSHSVEAAVQYASDDVGVVRVTAFQTRYTNLIDYRPGASGPYYVAQNVGRAKVQ
GVEGSWQGHVGGTDVRIAATLQNPVDETAGRDLNRRARRFASISANRSFGGWRVGGEWLASGARDDFGDRLGGYGIVNLS
ARYDITKSWYVSARIDNLFDKDYELAYAYNTPRRGAYVTLGWQQR

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: COG4206

COG function: function code H; Outer membrane cobalamin receptor protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790405, Length=624, Percent_Identity=28.525641025641, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1788478, Length=131, Percent_Identity=36.6412213740458, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 72574; Mature: 72574

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
0.1 %Met     (Translated Protein)
0.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
0.1 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTPFVRAALAALSGLPCIALAQGDASASSASFASSVSYAPAAASPADADSALSTAPAAA
CCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHCCCCHH
AASPASGAARGAEAVSADAASAVASGASSASPARAASAAQLAPVVVTARRGPQRLADAIP
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCEEEEECCCCHHHHHHHCC
QTTLFDARDIADSGATDLPGLLALAPGAQIVRNGGPGASASLFLRGAQPTQSLVLIDGVR
CCEEECHHHHCCCCCCCCCCCEEECCCHHEEECCCCCCCEEEEEECCCCCCCEEEEECEE
VDSASLGQSQIAQLPLDQIERVEVVNGNVSSLYGSGAIGGVVQVFTKNGGNHPPRFDFSA
ECCCCCCHHHHHHCCHHHHCEEEEECCCHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCC
GYGSYHTQTQSAGASGRLDPDGRTTFSVSLARLKTDGFSALDPARKPQANPNANGYLNES
CCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEECCC
ASASLRHTFSDKWNAGVTYFQANGRNSYDDAYGSPADLNDLYSRVQQLSAFANGALADGW
CCCHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
TTRVSVSSGKDRNQSALNGAYTDHFNTDNRQYTWQNDFAIARGHKIQAGYERLDQSFESN
EEEEEECCCCCCCCHHHCCCCCCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHCC
KYSAPERHVNSGWLGYTGRIGDSRFQANVRRDQYSDFGGANSYYFGYGFDVTEHWTVSAS
CCCCCHHCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEEC
YSSAFRAPSFNDLYYPNSGNLSIRPERSHSVEAAVQYASDDVGVVRVTAFQTRYTNLIDY
HHHHCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHCCCCCCEEEEEEEHHHHHHHEEC
RPGASGPYYVAQNVGRAKVQGVEGSWQGHVGGTDVRIAATLQNPVDETAGRDLNRRARRF
CCCCCCCCHHHCCCCCEEEECCCCCCCCCCCCCCEEEEEEECCCHHHHHCCCHHHHHHHH
ASISANRSFGGWRVGGEWLASGARDDFGDRLGGYGIVNLSARYDITKSWYVSARIDNLFD
HHHCCCCCCCCEECCHHHHHCCCCCHHHHHCCCCEEEEEEEEEECCCEEEEEEEHHHHCC
KDYELAYAYNTPRRGAYVTLGWQQR
CCCEEEEEECCCCCCEEEEEECCCC
>Mature Secondary Structure
MRTPFVRAALAALSGLPCIALAQGDASASSASFASSVSYAPAAASPADADSALSTAPAAA
CCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHCCCCHH
AASPASGAARGAEAVSADAASAVASGASSASPARAASAAQLAPVVVTARRGPQRLADAIP
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCEEEEECCCCHHHHHHHCC
QTTLFDARDIADSGATDLPGLLALAPGAQIVRNGGPGASASLFLRGAQPTQSLVLIDGVR
CCEEECHHHHCCCCCCCCCCCEEECCCHHEEECCCCCCCEEEEEECCCCCCCEEEEECEE
VDSASLGQSQIAQLPLDQIERVEVVNGNVSSLYGSGAIGGVVQVFTKNGGNHPPRFDFSA
ECCCCCCHHHHHHCCHHHHCEEEEECCCHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCC
GYGSYHTQTQSAGASGRLDPDGRTTFSVSLARLKTDGFSALDPARKPQANPNANGYLNES
CCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEECCC
ASASLRHTFSDKWNAGVTYFQANGRNSYDDAYGSPADLNDLYSRVQQLSAFANGALADGW
CCCHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
TTRVSVSSGKDRNQSALNGAYTDHFNTDNRQYTWQNDFAIARGHKIQAGYERLDQSFESN
EEEEEECCCCCCCCHHHCCCCCCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHCC
KYSAPERHVNSGWLGYTGRIGDSRFQANVRRDQYSDFGGANSYYFGYGFDVTEHWTVSAS
CCCCCHHCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEEC
YSSAFRAPSFNDLYYPNSGNLSIRPERSHSVEAAVQYASDDVGVVRVTAFQTRYTNLIDY
HHHHCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHCCCCCCEEEEEEEHHHHHHHEEC
RPGASGPYYVAQNVGRAKVQGVEGSWQGHVGGTDVRIAATLQNPVDETAGRDLNRRARRF
CCCCCCCCHHHCCCCCEEEECCCCCCCCCCCCCCEEEEEEECCCHHHHHCCCHHHHHHHH
ASISANRSFGGWRVGGEWLASGARDDFGDRLGGYGIVNLSARYDITKSWYVSARIDNLFD
HHHCCCCCCCCEECCHHHHHCCCCCHHHHHCCCCEEEEEEEEEECCCEEEEEEEHHHHCC
KDYELAYAYNTPRRGAYVTLGWQQR
CCCEEEEEECCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA