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The map label for this gene is hsp90 [H]

Identifier: 126451945

GI number: 126451945

Start: 1147600

End: 1149498

Strand: Direct

Name: hsp90 [H]

Synonym: BURPS1106A_1167

Alternate gene names: 126451945

Gene position: 1147600-1149498 (Clockwise)

Preceding gene: 126455072

Following gene: 126452801

Centisome position: 28.77

GC content: 64.35

Gene sequence:

>1899_bases
ATGACTCAGCAAACCATGAGCTTTCAGGCAGAGGTGAAGCAGCTCCTCCACCTGATGATTCATTCGCTTTACAGCAACAA
GGAAATCTTCCTGCGCGAACTCGTGTCCAACGCGTCCGACGCCGCTGACAAGCTCCGTTTCGAGGCTCTGGAAAACAACG
CGCTGTACGAGAGCGATCCGAATCTGCGCATTCGCCTGTCGTTCGACAAGGCCGCGCGTACGATCACGATCGACGACAAC
GGCATCGGCATGAGCCGTGACGAGGCGATCGCGAACCTCGGCACGATCGCGCGCTCGGGCACGAAGGAATTCTTCTCGAA
GCTCTCCGGCGACCAGCAGAAGGACGCGGCGCTCATCGGCCAGTTCGGCGTGGGCTTCTATTCGGGTTTCATCGTCGCGG
ACAGGATCACCGTCGAGACGCGCCGCGCGGGCCTGCCGGCGTCCGAGGGCGTGCGCTGGGAAAGCGCGGGCGAAGGGGAT
TTCCAGGTCGACACGATCGAGCGCGCCGCGCGCGGCACGACGATCACGCTGCATCTGCGCGAAGGCGAGGATGAGCTGCT
GTCGTCGTACCGGCTGAAATCGATCGTCCAGAAGTATTCGGACCACGTCGCGCTGCCGATCCTGATGAAGAAGGAGGAGT
GGGATCAGGAAAAGGGCGAGATGGTCGAGAAGGACGAGGACGAGACCATCAACCAGGCGAGCGCGCTGTGGACGCGCGCG
AAGAGCGAGGTCACCGACGAGCAGTACAAGCAGTTCTACCAGCACGTCGCGCACGATCACCAGGATCCGCTCGCGTGGAC
CCACAACCGCGTCGAGGGCCGCAGCGAATACACGCAGTTGCTGTTCGTGCCGTCGCACGCGCCGTTCGATCTGTGGAACC
GCGACTATCGCGGCGGCCTCAAGCTGTACGTGAAGCGCGTGTTCATCATGGACGACGCCGAGCAGTTGCTGCCGCAGTAC
CTGCGCTTCATCAAGGGCGTCGTCGATTCGTCGGATCTGCCGCTGAACGTGTCGCGCGAGATCCTGCAGGAAAGCCGCGA
CGTGAAGGCGATCCGCGAGGGCGTGACCAAGCGCGCGCTGTCGATGCTCGAGGAGCTCGCGAACGCCGAGGACGATGCGG
GCAAGGAGAAGTACAAGACGTTCTGGAGCGCGTTCGGCCAGGTGCTGAAGGAAGGCGTCGGCGAGGATCACGCGAACCGC
GAGCGCGTCGCGAAGCTGCTGCGCTTCGCGTCGACGCACGGCGACACCGACGCGCAGGACGTGGCGCTCGCCGACTACGT
CGCGCGGATGAAGCCCGAGCAAACGAAGCTCTACTACGTGACGGCCGATACGTGGCAGGCCGCGAAGAACAGCCCGCATC
TCGAGGTGTTCCGCAAGAAGGGCGTCGAGGTGCTGCTGCTCACCGATCGCGTCGACGAATGGATGCTGTCGTTCCTGCAC
GAGTTCGACGGCAAGCCGCTCGCGAGCGTCGCGCGCGGCGATCTCGATCTCGGCGCGCTGAACGACGACGAGAAGAAGGC
GCAGGAAGAGACGGGCGAGGCGATGAAGCCCGTCGTCGACAAGATGAAGGAGACGCTCGGCGAGAAGGTGAAGGACGTGC
GCGTCACGTTCCGGCTGACCGATTCGCCGTCGTGCCTCGTCGCCGACGACAACGACATGAGCGGCTACCTGCAGCGGATG
CTGAAGGCGGCGGGCCAGAGCGCGCCGTCGTTCCAGCCGATTCTCGAGATCAATCCGGAGCATCCGCTCGTCAAGGCGCT
GAAGGCCGACGGCGCGGATTTCGGCGACTGGTGCCACCTGCTGTTCGATCAGGCGCTGCTCGCCGAAGGCGGCGCGCTCG
AGGATCCGGCGAGCTTCGTGAAGCGGACCAACGCGCTGCTGCTGTCGCGCGCGGCGTGA

Upstream 100 bases:

>100_bases
AGCGTTGCGGCGGTCGGCACGCCGCCGTCGCGCGCCGGCTCCGATGGGGTCGTGAATCGAAACTGTCTGTCGTATTGACG
CAATCAACAGGTAAATCAAG

Downstream 100 bases:

>100_bases
TGGCGCGGATGCGTTTCGACGCCGCCGATGCGCACTGGCGCGAGACGCCGCGCCCCGGCGCGTCGAGCGCGCAGAAGGAC
TGGCTCACGCGCGGCGGCTC

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 632; Mature: 631

Protein sequence:

>632_residues
MTQQTMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAADKLRFEALENNALYESDPNLRIRLSFDKAARTITIDDN
GIGMSRDEAIANLGTIARSGTKEFFSKLSGDQQKDAALIGQFGVGFYSGFIVADRITVETRRAGLPASEGVRWESAGEGD
FQVDTIERAARGTTITLHLREGEDELLSSYRLKSIVQKYSDHVALPILMKKEEWDQEKGEMVEKDEDETINQASALWTRA
KSEVTDEQYKQFYQHVAHDHQDPLAWTHNRVEGRSEYTQLLFVPSHAPFDLWNRDYRGGLKLYVKRVFIMDDAEQLLPQY
LRFIKGVVDSSDLPLNVSREILQESRDVKAIREGVTKRALSMLEELANAEDDAGKEKYKTFWSAFGQVLKEGVGEDHANR
ERVAKLLRFASTHGDTDAQDVALADYVARMKPEQTKLYYVTADTWQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLH
EFDGKPLASVARGDLDLGALNDDEKKAQEETGEAMKPVVDKMKETLGEKVKDVRVTFRLTDSPSCLVADDNDMSGYLQRM
LKAAGQSAPSFQPILEINPEHPLVKALKADGADFGDWCHLLFDQALLAEGGALEDPASFVKRTNALLLSRAA

Sequences:

>Translated_632_residues
MTQQTMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAADKLRFEALENNALYESDPNLRIRLSFDKAARTITIDDN
GIGMSRDEAIANLGTIARSGTKEFFSKLSGDQQKDAALIGQFGVGFYSGFIVADRITVETRRAGLPASEGVRWESAGEGD
FQVDTIERAARGTTITLHLREGEDELLSSYRLKSIVQKYSDHVALPILMKKEEWDQEKGEMVEKDEDETINQASALWTRA
KSEVTDEQYKQFYQHVAHDHQDPLAWTHNRVEGRSEYTQLLFVPSHAPFDLWNRDYRGGLKLYVKRVFIMDDAEQLLPQY
LRFIKGVVDSSDLPLNVSREILQESRDVKAIREGVTKRALSMLEELANAEDDAGKEKYKTFWSAFGQVLKEGVGEDHANR
ERVAKLLRFASTHGDTDAQDVALADYVARMKPEQTKLYYVTADTWQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLH
EFDGKPLASVARGDLDLGALNDDEKKAQEETGEAMKPVVDKMKETLGEKVKDVRVTFRLTDSPSCLVADDNDMSGYLQRM
LKAAGQSAPSFQPILEINPEHPLVKALKADGADFGDWCHLLFDQALLAEGGALEDPASFVKRTNALLLSRAA
>Mature_631_residues
TQQTMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAADKLRFEALENNALYESDPNLRIRLSFDKAARTITIDDNG
IGMSRDEAIANLGTIARSGTKEFFSKLSGDQQKDAALIGQFGVGFYSGFIVADRITVETRRAGLPASEGVRWESAGEGDF
QVDTIERAARGTTITLHLREGEDELLSSYRLKSIVQKYSDHVALPILMKKEEWDQEKGEMVEKDEDETINQASALWTRAK
SEVTDEQYKQFYQHVAHDHQDPLAWTHNRVEGRSEYTQLLFVPSHAPFDLWNRDYRGGLKLYVKRVFIMDDAEQLLPQYL
RFIKGVVDSSDLPLNVSREILQESRDVKAIREGVTKRALSMLEELANAEDDAGKEKYKTFWSAFGQVLKEGVGEDHANRE
RVAKLLRFASTHGDTDAQDVALADYVARMKPEQTKLYYVTADTWQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLHE
FDGKPLASVARGDLDLGALNDDEKKAQEETGEAMKPVVDKMKETLGEKVKDVRVTFRLTDSPSCLVADDNDMSGYLQRML
KAAGQSAPSFQPILEINPEHPLVKALKADGADFGDWCHLLFDQALLAEGGALEDPASFVKRTNALLLSRAA

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI20149594, Length=686, Percent_Identity=39.2128279883382, Blast_Score=440, Evalue=1e-123,
Organism=Homo sapiens, GI4507677, Length=688, Percent_Identity=37.2093023255814, Blast_Score=413, Evalue=1e-115,
Organism=Homo sapiens, GI155722983, Length=639, Percent_Identity=35.2112676056338, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI154146191, Length=414, Percent_Identity=40.0966183574879, Blast_Score=287, Evalue=2e-77,
Organism=Homo sapiens, GI153792590, Length=414, Percent_Identity=40.0966183574879, Blast_Score=283, Evalue=2e-76,
Organism=Escherichia coli, GI1786679, Length=629, Percent_Identity=61.3672496025437, Blast_Score=793, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=671, Percent_Identity=38.1520119225037, Blast_Score=451, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI17542208, Length=675, Percent_Identity=38.2222222222222, Blast_Score=395, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI115535205, Length=648, Percent_Identity=32.5617283950617, Blast_Score=321, Evalue=6e-88,
Organism=Caenorhabditis elegans, GI115535167, Length=435, Percent_Identity=34.0229885057471, Blast_Score=248, Evalue=6e-66,
Organism=Saccharomyces cerevisiae, GI6323840, Length=682, Percent_Identity=39.0029325513196, Blast_Score=459, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6325016, Length=686, Percent_Identity=38.4839650145773, Blast_Score=456, Evalue=1e-129,
Organism=Drosophila melanogaster, GI17647529, Length=685, Percent_Identity=39.2700729927007, Blast_Score=460, Evalue=1e-129,
Organism=Drosophila melanogaster, GI21357739, Length=675, Percent_Identity=36.8888888888889, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24586016, Length=651, Percent_Identity=33.9477726574501, Blast_Score=354, Evalue=8e-98,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71150; Mature: 71019

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQTMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAADKLRFEALENNALYESDP
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCC
NLRIRLSFDKAARTITIDDNGIGMSRDEAIANLGTIARSGTKEFFSKLSGDQQKDAALIG
CEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHH
QFGVGFYSGFIVADRITVETRRAGLPASEGVRWESAGEGDFQVDTIERAARGTTITLHLR
HHHHHHHHCEEEEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEE
EGEDELLSSYRLKSIVQKYSDHVALPILMKKEEWDQEKGEMVEKDEDETINQASALWTRA
CCHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHCHHHCCCCCCCCHHHHHHHHHHHHHH
KSEVTDEQYKQFYQHVAHDHQDPLAWTHNRVEGRSEYTQLLFVPSHAPFDLWNRDYRGGL
HHHCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCEEEEEECCCCCHHHCCCCCCCCH
KLYVKRVFIMDDAEQLLPQYLRFIKGVVDSSDLPLNVSREILQESRDVKAIREGVTKRAL
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SMLEELANAEDDAGKEKYKTFWSAFGQVLKEGVGEDHANRERVAKLLRFASTHGDTDAQD
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHH
VALADYVARMKPEQTKLYYVTADTWQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLH
HHHHHHHHHCCCCCCEEEEEECCCHHHHCCCCHHHHHHHCCCEEEEEECHHHHHHHHHHH
EFDGKPLASVARGDLDLGALNDDEKKAQEETGEAMKPVVDKMKETLGEKVKDVRVTFRLT
HCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEE
DSPSCLVADDNDMSGYLQRMLKAAGQSAPSFQPILEINPEHPLVKALKADGADFGDWCHL
CCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHCCCCCHHHHHHH
LFDQALLAEGGALEDPASFVKRTNALLLSRAA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TQQTMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAADKLRFEALENNALYESDP
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCC
NLRIRLSFDKAARTITIDDNGIGMSRDEAIANLGTIARSGTKEFFSKLSGDQQKDAALIG
CEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHH
QFGVGFYSGFIVADRITVETRRAGLPASEGVRWESAGEGDFQVDTIERAARGTTITLHLR
HHHHHHHHCEEEEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEE
EGEDELLSSYRLKSIVQKYSDHVALPILMKKEEWDQEKGEMVEKDEDETINQASALWTRA
CCHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHCHHHCCCCCCCCHHHHHHHHHHHHHH
KSEVTDEQYKQFYQHVAHDHQDPLAWTHNRVEGRSEYTQLLFVPSHAPFDLWNRDYRGGL
HHHCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCEEEEEECCCCCHHHCCCCCCCCH
KLYVKRVFIMDDAEQLLPQYLRFIKGVVDSSDLPLNVSREILQESRDVKAIREGVTKRAL
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SMLEELANAEDDAGKEKYKTFWSAFGQVLKEGVGEDHANRERVAKLLRFASTHGDTDAQD
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHH
VALADYVARMKPEQTKLYYVTADTWQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLH
HHHHHHHHHCCCCCCEEEEEECCCHHHHCCCCHHHHHHHCCCEEEEEECHHHHHHHHHHH
EFDGKPLASVARGDLDLGALNDDEKKAQEETGEAMKPVVDKMKETLGEKVKDVRVTFRLT
HCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEE
DSPSCLVADDNDMSGYLQRMLKAAGQSAPSFQPILEINPEHPLVKALKADGADFGDWCHL
CCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHCCCCCHHHHHHH
LFDQALLAEGGALEDPASFVKRTNALLLSRAA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA