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The map label for this gene is pchC

Identifier: 126443306

GI number: 126443306

Start: 847431

End: 848204

Strand: Reverse

Name: pchC

Synonym: BURPS668_A0873

Alternate gene names: NA

Gene position: 848204-847431 (Counterclockwise)

Preceding gene: 126444853

Following gene: 126443288

Centisome position: 27.12

GC content: 72.35

Gene sequence:

>774_bases
ATGAAGCCGCCGCCTCCGCACGCCGGCTGGGTTCGCGAACTCAGGCTGTCGCCCTGCCCGCGCGCGCAGCTCGTCTGCAT
GCCGCACGCGGGCGGCGCCGCAAGTTTCTTTCGCGGCTGGGCAGGCGCGCTGCCGTGGGATCTCGATCTGCTCGCGCTTC
AATATCCGGGCCGCGAGGACCGCTTCGGCGAACCGTGCGCGCGCTCGATCGACGCGCTCGCCGGCCCCGCCGCCGAAGCG
CTCGTCGAGTACGCGCGCCAGCCGCTCGTGCTGTTCGGCCACAGCCTGGGCGCCGCGCTCGCCTACGAAGTCGCGTTGCG
CCTCGAGCAGCGCGGCGCGCCGCCGCTGTATGTCGCGGTCTCGTCGCATCCGCCGCCGCACCGGCAGCGCGCGTCGAGCC
TGCACCTGCAATCCGACGCCGCGCTGCTGAACGACGTCGCGCGGCTGTCCGGCGAACACGCGGCGCTGCTCGACGATCCG
GCGCTGCGCGCGATCTATCTGCCGATGATCCGCGACGACTATCGCGCGATCGAGACCTACCGGCGCGAGCGGCCGCCGAT
GCTCGACGCGCCGCTCGGCGTGATGCTGCCGCTCGCCGATCCCGAGCTCGACCGCGACGAAGCGCAGGCCTGGCAGGACG
TCGCGTCCCGGCCGATCCGCGTGACGACGTTCGACGGCGACCATTTCTATCTGCGCCACGCGTACCCGGCGCTCATCGCG
CACATCGCCGGGCAGATCGACCGCTCGCTGCGCCCACTCAAGGAACACGCATGA

Upstream 100 bases:

>100_bases
GCATCGAATTCGTGCCGAGCTTTCCGGAAACCGGCATCGGCAAGACCAGCAAGAAATCGCTGCGCGACCTGCTGCGCCGC
CGGCTCGAAGCGGCGCGCGC

Downstream 100 bases:

>100_bases
AGACACCGGACCAATGCACGGGCCTCGCCGACATCCGCGAAGCCATCGACCGCCTCGACGCCGACATCATCGCGGCGCTC
GGCGCGCGCATGCAATACGT

Product: pyochelin biosynthetic protein PchC

Products: NA

Alternate protein names: ORF-1; Protein X [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKPPPPHAGWVRELRLSPCPRAQLVCMPHAGGAASFFRGWAGALPWDLDLLALQYPGREDRFGEPCARSIDALAGPAAEA
LVEYARQPLVLFGHSLGAALAYEVALRLEQRGAPPLYVAVSSHPPPHRQRASSLHLQSDAALLNDVARLSGEHAALLDDP
ALRAIYLPMIRDDYRAIETYRRERPPMLDAPLGVMLPLADPELDRDEAQAWQDVASRPIRVTTFDGDHFYLRHAYPALIA
HIAGQIDRSLRPLKEHA

Sequences:

>Translated_257_residues
MKPPPPHAGWVRELRLSPCPRAQLVCMPHAGGAASFFRGWAGALPWDLDLLALQYPGREDRFGEPCARSIDALAGPAAEA
LVEYARQPLVLFGHSLGAALAYEVALRLEQRGAPPLYVAVSSHPPPHRQRASSLHLQSDAALLNDVARLSGEHAALLDDP
ALRAIYLPMIRDDYRAIETYRRERPPMLDAPLGVMLPLADPELDRDEAQAWQDVASRPIRVTTFDGDHFYLRHAYPALIA
HIAGQIDRSLRPLKEHA
>Mature_257_residues
MKPPPPHAGWVRELRLSPCPRAQLVCMPHAGGAASFFRGWAGALPWDLDLLALQYPGREDRFGEPCARSIDALAGPAAEA
LVEYARQPLVLFGHSLGAALAYEVALRLEQRGAPPLYVAVSSHPPPHRQRASSLHLQSDAALLNDVARLSGEHAALLDDP
ALRAIYLPMIRDDYRAIETYRRERPPMLDAPLGVMLPLADPELDRDEAQAWQDVASRPIRVTTFDGDHFYLRHAYPALIA
HIAGQIDRSLRPLKEHA

Specific function: Probable thioesterase involved in the biosynthesis of candicidin. Could release the macrolide ring from the polyketide synthase [H]

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI89257335, Length=223, Percent_Identity=26.0089686098655, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR010693
- InterPro:   IPR012223
- InterPro:   IPR001031 [H]

Pfam domain/function: PF06902 DUF1271; PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 28393; Mature: 28393

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPPPPHAGWVRELRLSPCPRAQLVCMPHAGGAASFFRGWAGALPWDLDLLALQYPGRED
CCCCCCCCHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCC
RFGEPCARSIDALAGPAAEALVEYARQPLVLFGHSLGAALAYEVALRLEQRGAPPLYVAV
CCCCHHHHHHHHHCCHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEE
SSHPPPHRQRASSLHLQSDAALLNDVARLSGEHAALLDDPALRAIYLPMIRDDYRAIETY
CCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHH
RRERPPMLDAPLGVMLPLADPELDRDEAQAWQDVASRPIRVTTFDGDHFYLRHAYPALIA
HHCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCEEEEHHHHHHHHH
HIAGQIDRSLRPLKEHA
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKPPPPHAGWVRELRLSPCPRAQLVCMPHAGGAASFFRGWAGALPWDLDLLALQYPGRED
CCCCCCCCHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCC
RFGEPCARSIDALAGPAAEALVEYARQPLVLFGHSLGAALAYEVALRLEQRGAPPLYVAV
CCCCHHHHHHHHHCCHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEE
SSHPPPHRQRASSLHLQSDAALLNDVARLSGEHAALLDDPALRAIYLPMIRDDYRAIETY
CCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHH
RRERPPMLDAPLGVMLPLADPELDRDEAQAWQDVASRPIRVTTFDGDHFYLRHAYPALIA
HHCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCEEEEHHHHHHHHH
HIAGQIDRSLRPLKEHA
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8472954 [H]