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The map label for this gene is glpT [H]

Identifier: 126209297

GI number: 126209297

Start: 2058079

End: 2059236

Strand: Reverse

Name: glpT [H]

Synonym: APL_1835

Alternate gene names: 126209297

Gene position: 2059236-2058079 (Counterclockwise)

Preceding gene: 126209299

Following gene: 126209296

Centisome position: 90.54

GC content: 43.44

Gene sequence:

>1158_bases
ATGTTACTTTCCTGTTTAACCATTTCTTACGGCTTGGCAAAATTTTATATGGGCGCATTGGGCGATCGTGTCGATTTACG
TAAATTGTTTGCGATCTGTTTAGGGGCAAGCGCCGTGATTTGTATTACGATCGGTTTCTACCATACTTCGATCCTCACTC
TTGCCGTTTTACTGGTACTTTGCGGTGTGGTGCAAGGTGCACTGGCTCCGGCATCACAAAATATGATTGCAAATTATTAC
CCGAACAAAACCCGCGGGGCGGCTATCGCAGGTTGGAATATTTCACAAAATATGGGGTCTGCGTTATTACCGATGATGAT
TGCAATGATGACGACGATGGGTTTTATCGTGCCTTCAACCGGTAATGTATTGATGGCATTCTTAGTACCTGCCGTTTTAG
TTTTATTATTTGCGGTATTTTGTTGGAAATTCGGTGGCGATGCGCCGGAAAAAGAAGGATTGGATTCACTCCGTACGATG
TATGGCGATGCAGGCGAATCTAATGTCGCTTCCGAAGAAGAAAAACATAATTTAGGTTATTGGCAACTTATCGGTAAATA
TGTATTCCTCAACCCCGCACTACTATTGGTTGCGGCAGTAAACGTCGCACTATACTTCGTTCGCTTAGGCATTGAGGACT
GGATGCCGATTTATTTACATGAAGTGGCGAAAATGGGCGATGCGGAATCCCATATGGCAATCTCGATTCTTGAATGGGTC
GCGATTCCGGGTTCATTAGTATTCGCATGGTTAGCGGTTAAATATCCGAATAAAATGGCAAAAATGGGTGCAATCGGATT
ATTCATTATGGCGGGTATCGTATTCGCTTATGAATATGTTACCGCAAGCGGTGCGCCTAACTATCCGTTATTACTGGTAA
TTTGCGGTATTTTAGGAGCTTTAATTTATGGTCCGCAATTAATCGTAAATATTTTAACCATTAACTTCGTCCCGCTAAAT
GTTGCCGGTACCGCAATCGGCTTTGTCGGTGTCACCGCTTACTTAATCGGTAATATGGGCGCAAACTGGATTATGCCGAT
TATGGCGGATAACTTCGGTTGGTTCTGGTCTTATGTAGTCATTGCCGCGCTTTCCGCATTTTCTGCCGTCGGTTACTTAA
TATTGGCTAAACACGAAGAGAAAACGATAAAAGCCTAA

Upstream 100 bases:

>100_bases
TTTGCTCGGCTATGTCTGCGCTTATTTAGTCCGTAACAATTTTAAATTAATGTCTAAATCCATTATGGTCACAAACGGTT
GGGAAAAAGCGGATATTGCG

Downstream 100 bases:

>100_bases
ATTCCTATTTTTATAAATCTAAAAAAAGCCGAGTGACTATATTTGAACTCGGTTTTTTTATTTGAATCTAATCTGCTCGT
AAGAAAAACAGACGAGAAAG

Product: glycerol-3-phosphate transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MLLSCLTISYGLAKFYMGALGDRVDLRKLFAICLGASAVICITIGFYHTSILTLAVLLVLCGVVQGALAPASQNMIANYY
PNKTRGAAIAGWNISQNMGSALLPMMIAMMTTMGFIVPSTGNVLMAFLVPAVLVLLFAVFCWKFGGDAPEKEGLDSLRTM
YGDAGESNVASEEEKHNLGYWQLIGKYVFLNPALLLVAAVNVALYFVRLGIEDWMPIYLHEVAKMGDAESHMAISILEWV
AIPGSLVFAWLAVKYPNKMAKMGAIGLFIMAGIVFAYEYVTASGAPNYPLLLVICGILGALIYGPQLIVNILTINFVPLN
VAGTAIGFVGVTAYLIGNMGANWIMPIMADNFGWFWSYVVIAALSAFSAVGYLILAKHEEKTIKA

Sequences:

>Translated_385_residues
MLLSCLTISYGLAKFYMGALGDRVDLRKLFAICLGASAVICITIGFYHTSILTLAVLLVLCGVVQGALAPASQNMIANYY
PNKTRGAAIAGWNISQNMGSALLPMMIAMMTTMGFIVPSTGNVLMAFLVPAVLVLLFAVFCWKFGGDAPEKEGLDSLRTM
YGDAGESNVASEEEKHNLGYWQLIGKYVFLNPALLLVAAVNVALYFVRLGIEDWMPIYLHEVAKMGDAESHMAISILEWV
AIPGSLVFAWLAVKYPNKMAKMGAIGLFIMAGIVFAYEYVTASGAPNYPLLLVICGILGALIYGPQLIVNILTINFVPLN
VAGTAIGFVGVTAYLIGNMGANWIMPIMADNFGWFWSYVVIAALSAFSAVGYLILAKHEEKTIKA
>Mature_385_residues
MLLSCLTISYGLAKFYMGALGDRVDLRKLFAICLGASAVICITIGFYHTSILTLAVLLVLCGVVQGALAPASQNMIANYY
PNKTRGAAIAGWNISQNMGSALLPMMIAMMTTMGFIVPSTGNVLMAFLVPAVLVLLFAVFCWKFGGDAPEKEGLDSLRTM
YGDAGESNVASEEEKHNLGYWQLIGKYVFLNPALLLVAAVNVALYFVRLGIEDWMPIYLHEVAKMGDAESHMAISILEWV
AIPGSLVFAWLAVKYPNKMAKMGAIGLFIMAGIVFAYEYVTASGAPNYPLLLVICGILGALIYGPQLIVNILTINFVPLN
VAGTAIGFVGVTAYLIGNMGANWIMPIMADNFGWFWSYVVIAALSAFSAVGYLILAKHEEKTIKA

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Escherichia coli, GI1788573, Length=385, Percent_Identity=29.0909090909091, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI87082310, Length=372, Percent_Identity=28.7634408602151, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI2367259, Length=394, Percent_Identity=26.9035532994924, Blast_Score=133, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41492; Mature: 41492

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLSCLTISYGLAKFYMGALGDRVDLRKLFAICLGASAVICITIGFYHTSILTLAVLLVL
CEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHH
CGVVQGALAPASQNMIANYYPNKTRGAAIAGWNISQNMGSALLPMMIAMMTTMGFIVPST
HHHHHHHCCCCCCCCHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHEECCC
GNVLMAFLVPAVLVLLFAVFCWKFGGDAPEKEGLDSLRTMYGDAGESNVASEEEKHNLGY
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCHH
WQLIGKYVFLNPALLLVAAVNVALYFVRLGIEDWMPIYLHEVAKMGDAESHMAISILEWV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHH
AIPGSLVFAWLAVKYPNKMAKMGAIGLFIMAGIVFAYEYVTASGAPNYPLLLVICGILGA
HCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LIYGPQLIVNILTINFVPLNVAGTAIGFVGVTAYLIGNMGANWIMPIMADNFGWFWSYVV
HHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHH
IAALSAFSAVGYLILAKHEEKTIKA
HHHHHHHHHHHHHEEEECCHHCCCC
>Mature Secondary Structure
MLLSCLTISYGLAKFYMGALGDRVDLRKLFAICLGASAVICITIGFYHTSILTLAVLLVL
CEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHH
CGVVQGALAPASQNMIANYYPNKTRGAAIAGWNISQNMGSALLPMMIAMMTTMGFIVPST
HHHHHHHCCCCCCCCHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHEECCC
GNVLMAFLVPAVLVLLFAVFCWKFGGDAPEKEGLDSLRTMYGDAGESNVASEEEKHNLGY
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCHH
WQLIGKYVFLNPALLLVAAVNVALYFVRLGIEDWMPIYLHEVAKMGDAESHMAISILEWV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHH
AIPGSLVFAWLAVKYPNKMAKMGAIGLFIMAGIVFAYEYVTASGAPNYPLLLVICGILGA
HCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LIYGPQLIVNILTINFVPLNVAGTAIGFVGVTAYLIGNMGANWIMPIMADNFGWFWSYVV
HHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHH
IAALSAFSAVGYLILAKHEEKTIKA
HHHHHHHHHHHHHEEEECCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3329281; 9205837; 9278503; 3141744; 12893936 [H]