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The map label for this gene is fucU

Identifier: 126209150

GI number: 126209150

Start: 1917421

End: 1917855

Strand: Direct

Name: fucU

Synonym: APL_1686

Alternate gene names: 126209150

Gene position: 1917421-1917855 (Clockwise)

Preceding gene: 126209149

Following gene: 126209151

Centisome position: 84.3

GC content: 47.36

Gene sequence:

>435_bases
ATGTTAAAAGGTATTCATCCGGCAATTTCTCCGGAATTACTCAAAGTGTTAGCGGAAATGGGGCACGGTGACGAATTAGT
CCTTTCCGATGCGCACTTTCCGGCGCATTCGATTCATTCCAAAGTGATTCGTGCGGACGGTATCGGTGTTGCCACTTTAT
TAGAAGGAATTTCGGCGTTGTTTGAATTCGACCAGTATGTCGAAGCCCCGTTAGCAATGATGCAAGCCGTACCGGGCGAC
ACGTTGGATCCGAGTGTCGAAGAACGTTATTTAGCCGCAATTAAAAAAGTAAACGGCAGCACCCCGAAAGTCGAGCGAGT
AGAACGCTTTGCTTTTTACGATCGTGCGAAAACCGCTTATGCGGTCGTGATTACCGGCGAGTTAGCGAAATACGGCAACA
TCATCATCAAAAAAGGGGTTACGCCCGTTAAATAA

Upstream 100 bases:

>100_bases
CAAGCGATCGAATTTCTTGCCGGCTTTGTGAAGTGCTGCCCAAAAACGACCGCTTGGTGAAAATTTAGGCATTCGTTCTA
GGAAAAAACAGGAGTTCAAG

Downstream 100 bases:

>100_bases
AAATTTACACCATTAACAGAATTCATCATAAAAAATTAAAGGAGTTCACTATGAATCGCAGAGAACTAGCTCGACAAATC
ATCGATACTTGCCTTGAAAT

Product: fucose operon FucU protein

Products: NA

Alternate protein names: Fucose 1-epimerase; Type-2 mutarotase

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MLKGIHPAISPELLKVLAEMGHGDELVLSDAHFPAHSIHSKVIRADGIGVATLLEGISALFEFDQYVEAPLAMMQAVPGD
TLDPSVEERYLAAIKKVNGSTPKVERVERFAFYDRAKTAYAVVITGELAKYGNIIIKKGVTPVK

Sequences:

>Translated_144_residues
MLKGIHPAISPELLKVLAEMGHGDELVLSDAHFPAHSIHSKVIRADGIGVATLLEGISALFEFDQYVEAPLAMMQAVPGD
TLDPSVEERYLAAIKKVNGSTPKVERVERFAFYDRAKTAYAVVITGELAKYGNIIIKKGVTPVK
>Mature_144_residues
MLKGIHPAISPELLKVLAEMGHGDELVLSDAHFPAHSIHSKVIRADGIGVATLLEGISALFEFDQYVEAPLAMMQAVPGD
TLDPSVEERYLAAIKKVNGSTPKVERVERFAFYDRAKTAYAVVITGELAKYGNIIIKKGVTPVK

Specific function: Involved in the anomeric conversion of L-fucose

COG id: COG4154

COG function: function code G; Fucose dissimilation pathway protein FucU

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rbsD / fucU family. FucU mutarotase subfamily

Homologues:

Organism=Homo sapiens, GI148596947, Length=145, Percent_Identity=48.9655172413793, Blast_Score=132, Evalue=1e-31,
Organism=Homo sapiens, GI148596951, Length=131, Percent_Identity=47.3282442748092, Blast_Score=112, Evalue=9e-26,
Organism=Escherichia coli, GI1789169, Length=142, Percent_Identity=64.0845070422535, Blast_Score=182, Evalue=5e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FUCM_ACTP2 (A3N2Y4)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001054375.1
- ProteinModelPortal:   A3N2Y4
- SMR:   A3N2Y4
- STRING:   A3N2Y4
- GeneID:   4849287
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1686
- eggNOG:   COG4154
- HOGENOM:   HBG510403
- OMA:   GDEVAIC
- PhylomeDB:   A3N2Y4
- ProtClustDB:   CLSK2518364
- BioCyc:   APLE416269:APL_1686-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01662
- InterPro:   IPR007721

Pfam domain/function: PF05025 RbsD_FucU; SSF102546 RbsD_FucU

EC number: NA

Molecular weight: Translated: 15614; Mature: 15614

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: ACT_SITE 22-22 BINDING 30-30 BINDING 109-109

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKGIHPAISPELLKVLAEMGHGDELVLSDAHFPAHSIHSKVIRADGIGVATLLEGISAL
CCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHH
FEFDQYVEAPLAMMQAVPGDTLDPSVEERYLAAIKKVNGSTPKVERVERFAFYDRAKTAY
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEE
AVVITGELAKYGNIIIKKGVTPVK
EEEEECCHHHHCCEEEECCCCCCC
>Mature Secondary Structure
MLKGIHPAISPELLKVLAEMGHGDELVLSDAHFPAHSIHSKVIRADGIGVATLLEGISAL
CCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHH
FEFDQYVEAPLAMMQAVPGDTLDPSVEERYLAAIKKVNGSTPKVERVERFAFYDRAKTAY
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEE
AVVITGELAKYGNIIIKKGVTPVK
EEEEECCHHHHCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA