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The map label for this gene is atpC

Identifier: 126209109

GI number: 126209109

Start: 1873346

End: 1873765

Strand: Reverse

Name: atpC

Synonym: APL_1645

Alternate gene names: 126209109

Gene position: 1873765-1873346 (Counterclockwise)

Preceding gene: 126209110

Following gene: 126209103

Centisome position: 82.38

GC content: 39.05

Gene sequence:

>420_bases
ATGGCATCTCAATTTGAGCTTAGCGTAGTAAGTGCTGAAAAAGAAATCTTCAACGGTAATGTAGTGAGTGTTCGCGTCTC
AGGTATTGACGGGGAATTAGGTGTGTATGCAGGTCATACGCCCTTATTAACCTCTATTAAACCGGGTATGGTGAAGTACA
CGCTTGAAAATGGTAAAGAAGAGTTTATCTATGTATCCGGCGGCTTCTTAGAAGTCCAGCCTACTATTGTAACTGTTCTT
GCCGATGTAGCAATTCGAGGCGAAGAGTTAGATCAACAACGCATTCTTGCTGCAAAACGTAAAGCGGAAGATACGTTAAG
TAAATCAAATAATGCGGAGCTTTCTGCAAAACTATCTCGTGAAATTGCTAAATTACGTGTTTATGAAATTGTAAATTCAA
AATTAGCAAATAGACGTTAA

Upstream 100 bases:

>100_bases
ACAAGCGTTCTATATGGCGGGTTCTATTGACGAAGTAGTGGAAAGAGCGAGCAAGATGTAATTGTTCCCTGACCTCAATT
AGGAACTAAAGGAGAACAAT

Downstream 100 bases:

>100_bases
TCTAAAAAAACCTCAGTGAATTTCACTGAGGTTTTTCTTTTTTTATTTTTTGTGTTTATCTTCAAAATTCAGGTGTAAAG
AAACTAACGGAGAATGACTT

Product: F0F1 ATP synthase subunit epsilon

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F1 sector epsilon subunit; F-ATPase epsilon subunit

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MASQFELSVVSAEKEIFNGNVVSVRVSGIDGELGVYAGHTPLLTSIKPGMVKYTLENGKEEFIYVSGGFLEVQPTIVTVL
ADVAIRGEELDQQRILAAKRKAEDTLSKSNNAELSAKLSREIAKLRVYEIVNSKLANRR

Sequences:

>Translated_139_residues
MASQFELSVVSAEKEIFNGNVVSVRVSGIDGELGVYAGHTPLLTSIKPGMVKYTLENGKEEFIYVSGGFLEVQPTIVTVL
ADVAIRGEELDQQRILAAKRKAEDTLSKSNNAELSAKLSREIAKLRVYEIVNSKLANRR
>Mature_138_residues
ASQFELSVVSAEKEIFNGNVVSVRVSGIDGELGVYAGHTPLLTSIKPGMVKYTLENGKEEFIYVSGGFLEVQPTIVTVLA
DVAIRGEELDQQRILAAKRKAEDTLSKSNNAELSAKLSREIAKLRVYEIVNSKLANRR

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane

COG id: COG0355

COG function: function code C; F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase epsilon chain family

Homologues:

Organism=Escherichia coli, GI1790169, Length=139, Percent_Identity=53.2374100719424, Blast_Score=154, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPE_ACTP2 (A3N2U3)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001054334.1
- ProteinModelPortal:   A3N2U3
- SMR:   A3N2U3
- STRING:   A3N2U3
- GeneID:   4848768
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1645
- eggNOG:   COG0355
- HOGENOM:   HBG663981
- OMA:   SAEASIF
- PhylomeDB:   A3N2U3
- ProtClustDB:   PRK00571
- BioCyc:   APLE416269:APL_1645-MONOMER
- HAMAP:   MF_00530
- InterPro:   IPR001469
- InterPro:   IPR020547
- InterPro:   IPR020546
- Gene3D:   G3DSA:2.60.15.10
- PANTHER:   PTHR13822
- ProDom:   PD000944
- TIGRFAMs:   TIGR01216

Pfam domain/function: PF02823 ATP-synt_DE_N; SSF46604 ATPsynt_DE; SSF51344 ATPsynt_DE

EC number: 3.6.3.14

Molecular weight: Translated: 15226; Mature: 15094

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASQFELSVVSAEKEIFNGNVVSVRVSGIDGELGVYAGHTPLLTSIKPGMVKYTLENGKE
CCCCEEEEEEECHHHHCCCCEEEEEEECCCCCCCEEECCCCEEECCCCCEEEEEECCCCE
EFIYVSGGFLEVQPTIVTVLADVAIRGEELDQQRILAAKRKAEDTLSKSNNAELSAKLSR
EEEEEECCEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEHHHHHH
EIAKLRVYEIVNSKLANRR
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ASQFELSVVSAEKEIFNGNVVSVRVSGIDGELGVYAGHTPLLTSIKPGMVKYTLENGKE
CCCEEEEEEECHHHHCCCCEEEEEEECCCCCCCEEECCCCEEECCCCCEEEEEECCCCE
EFIYVSGGFLEVQPTIVTVLADVAIRGEELDQQRILAAKRKAEDTLSKSNNAELSAKLSR
EEEEEECCEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEHHHHHH
EIAKLRVYEIVNSKLANRR
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA