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The map label for this gene is atpD [H]

Identifier: 126209110

GI number: 126209110

Start: 1873805

End: 1875178

Strand: Reverse

Name: atpD [H]

Synonym: APL_1646

Alternate gene names: 126209110

Gene position: 1875178-1873805 (Counterclockwise)

Preceding gene: 126209111

Following gene: 126209109

Centisome position: 82.44

GC content: 43.01

Gene sequence:

>1374_bases
ATGGCAACAGGAAAAATTGTACAGATTATCGGTGCGGTAATCGACGTTGAATTCCCGCAAGATGCAGTACCAAAAGTATA
TGATGCCTTAAAAGTTGAATCGGGTTTAACCCTTGAGGTTCAACAACAATTAGGTGGTGGACTTGTGCGTTGTATCGCAT
TAGGTACATCAGACGGTTTAAAACGCGGCTTAAAAGTTGAAAATACGGGTAACCCGATTCAAGTACCGGTCGGTACCAAG
ACTCTAGGTCGTATTATGAACGTATTAGGTGAGCCGATCGATGAAAAAGGTCCTATCGGCGAAGAAGCTCGTTGGGATAT
TCACCGTGCGGCACCAAGCTACGAAGAACAATCAAACAGTACGGAATTACTTGAAACCGGTATTAAAGTTATCGACTTAA
TTTGTCCGTTCGCAAAAGGTGGTAAAGTCGGTTTATTCGGTGGTGCGGGTGTAGGTAAAACCGTTAATATGATGGAATTA
ATCCGTAATATCGCAATCGAACACTCCGGTTACTCAGTATTCGCAGGTGTTGGTGAGCGTACTCGTGAAGGTAATGACTT
CTATCACGAAATGACGGATTCTAACGTATTAGATAAAGTATCACTTGTTTACGGTCAGATGAACGAGCCGCCGGGTAACC
GTCTGCGTGTTGCATTAACCGGTTTAACAATGGCGGAAAAATTCCGTGATGAAGGTCGTGACGTGTTATTCTTCGTAGAT
AACATCTACCGTTATACACTTGCAGGTACGGAAGTATCGGCATTATTAGGTCGTATGCCGTCAGCGGTAGGTTACCAACC
TACACTTGCGGAAGAAATGGGTGTATTACAAGAACGTATTACATCAACCAAAACAGGTTCGATTACTTCTGTTCAAGCGG
TTTACGTTCCAGCGGATGACTTAACGGACCCATCTCCGGCAACAACTTTCGCACACTTAGACTCAACGGTTGTATTAAGT
CGTAATATCGCATCTCTTGGTATTTACCCTGCGGTTGATCCACTAGATTCAACTTCTCGTCAATTAGATCCATTAGTCGT
CGGTGAAGAACACTATAATGTAGCTCGTGGTGTACAAGGCACATTACAACGCTATAAAGAGTTAAAAGACATCATCGCTA
TTTTAGGTATGGATGAGTTATCTGAAGACGATAAATTAGTGGTTGCTCGTGCGCGTAAGATCGAACGTTTCTTATCACAA
CCATTCTTCGTTGCGGAAGTATTTACCGGTTCTCCGGGTAAATATGTATCGTTAAAAGATACAATCCGTGGCTTCAAAGG
TATCTTAGAAGGCGAATTCGACCATATTCCGGAACAAGCGTTCTATATGGCGGGTTCTATTGACGAAGTAGTGGAAAGAG
CGAGCAAGATGTAA

Upstream 100 bases:

>100_bases
GAATTACAATTAGTGTATAACAAAGCTCGCCAAGCAAGCATTACAAATGAATTAAACGAAATTGTTGCGGGTGCCGCAGC
AATTTAATGGAGAACAGGTA

Downstream 100 bases:

>100_bases
TTGTTCCCTGACCTCAATTAGGAACTAAAGGAGAACAATATGGCATCTCAATTTGAGCTTAGCGTAGTAAGTGCTGAAAA
AGAAATCTTCAACGGTAATG

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta [H]

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MATGKIVQIIGAVIDVEFPQDAVPKVYDALKVESGLTLEVQQQLGGGLVRCIALGTSDGLKRGLKVENTGNPIQVPVGTK
TLGRIMNVLGEPIDEKGPIGEEARWDIHRAAPSYEEQSNSTELLETGIKVIDLICPFAKGGKVGLFGGAGVGKTVNMMEL
IRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLFFVD
NIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDSTVVLS
RNIASLGIYPAVDPLDSTSRQLDPLVVGEEHYNVARGVQGTLQRYKELKDIIAILGMDELSEDDKLVVARARKIERFLSQ
PFFVAEVFTGSPGKYVSLKDTIRGFKGILEGEFDHIPEQAFYMAGSIDEVVERASKM

Sequences:

>Translated_457_residues
MATGKIVQIIGAVIDVEFPQDAVPKVYDALKVESGLTLEVQQQLGGGLVRCIALGTSDGLKRGLKVENTGNPIQVPVGTK
TLGRIMNVLGEPIDEKGPIGEEARWDIHRAAPSYEEQSNSTELLETGIKVIDLICPFAKGGKVGLFGGAGVGKTVNMMEL
IRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLFFVD
NIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDSTVVLS
RNIASLGIYPAVDPLDSTSRQLDPLVVGEEHYNVARGVQGTLQRYKELKDIIAILGMDELSEDDKLVVARARKIERFLSQ
PFFVAEVFTGSPGKYVSLKDTIRGFKGILEGEFDHIPEQAFYMAGSIDEVVERASKM
>Mature_456_residues
ATGKIVQIIGAVIDVEFPQDAVPKVYDALKVESGLTLEVQQQLGGGLVRCIALGTSDGLKRGLKVENTGNPIQVPVGTKT
LGRIMNVLGEPIDEKGPIGEEARWDIHRAAPSYEEQSNSTELLETGIKVIDLICPFAKGGKVGLFGGAGVGKTVNMMELI
RNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLFFVDN
IYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDSTVVLSR
NIASLGIYPAVDPLDSTSRQLDPLVVGEEHYNVARGVQGTLQRYKELKDIIAILGMDELSEDDKLVVARARKIERFLSQP
FFVAEVFTGSPGKYVSLKDTIRGFKGILEGEFDHIPEQAFYMAGSIDEVVERASKM

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=466, Percent_Identity=68.4549356223176, Blast_Score=638, Evalue=0.0,
Organism=Homo sapiens, GI19913428, Length=396, Percent_Identity=26.5151515151515, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI50345984, Length=303, Percent_Identity=26.4026402640264, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI4757810, Length=303, Percent_Identity=26.4026402640264, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI19913424, Length=321, Percent_Identity=27.1028037383178, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI19913426, Length=397, Percent_Identity=26.1964735516373, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1790170, Length=460, Percent_Identity=88.4782608695652, Blast_Score=837, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=335, Percent_Identity=29.8507462686567, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1790172, Length=340, Percent_Identity=26.7647058823529, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI25144756, Length=466, Percent_Identity=67.381974248927, Blast_Score=634, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17510931, Length=358, Percent_Identity=26.8156424581006, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17570191, Length=406, Percent_Identity=26.3546798029557, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17565854, Length=321, Percent_Identity=28.6604361370716, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71988080, Length=367, Percent_Identity=24.7956403269755, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=367, Percent_Identity=24.7956403269755, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71988074, Length=395, Percent_Identity=23.5443037974684, Blast_Score=88, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6322581, Length=458, Percent_Identity=67.6855895196507, Blast_Score=625, Evalue=1e-180,
Organism=Saccharomyces cerevisiae, GI6319603, Length=389, Percent_Identity=26.7352185089974, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6319370, Length=372, Percent_Identity=26.0752688172043, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6320016, Length=256, Percent_Identity=26.953125, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24638766, Length=465, Percent_Identity=67.5268817204301, Blast_Score=627, Evalue=1e-180,
Organism=Drosophila melanogaster, GI28574560, Length=465, Percent_Identity=64.0860215053764, Blast_Score=589, Evalue=1e-168,
Organism=Drosophila melanogaster, GI281361666, Length=390, Percent_Identity=26.9230769230769, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24646341, Length=390, Percent_Identity=26.9230769230769, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17136796, Length=390, Percent_Identity=26.9230769230769, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI20129479, Length=331, Percent_Identity=26.8882175226586, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24583992, Length=321, Percent_Identity=27.1028037383178, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24583988, Length=321, Percent_Identity=26.4797507788162, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24583986, Length=321, Percent_Identity=26.4797507788162, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24583984, Length=321, Percent_Identity=26.4797507788162, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24658560, Length=338, Percent_Identity=25.4437869822485, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24638768, Length=92, Percent_Identity=52.1739130434783, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 49678; Mature: 49547

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGKIVQIIGAVIDVEFPQDAVPKVYDALKVESGLTLEVQQQLGGGLVRCIALGTSDGL
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHCCCEEEEEEECCCHHH
KRGLKVENTGNPIQVPVGTKTLGRIMNVLGEPIDEKGPIGEEARWDIHRAAPSYEEQSNS
HCCCEECCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCHHCCCC
TELLETGIKVIDLICPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGER
HHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCC
TREGNDFYHEMTDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLFFVD
CCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEEEEEECHHHHHHHHHCCCEEEEEEE
NIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADD
CHHHEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCC
LTDPSPATTFAHLDSTVVLSRNIASLGIYPAVDPLDSTSRQLDPLVVGEEHYNVARGVQG
CCCCCCCCCHHHCCCEEEEECCHHHHCCCCCCCCCCCCHHHCCCEEECCCHHHHHHHHHH
TLQRYKELKDIIAILGMDELSEDDKLVVARARKIERFLSQPFFVAEVFTGSPGKYVSLKD
HHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEEHHH
TIRGFKGILEGEFDHIPEQAFYMAGSIDEVVERASKM
HHHHHHHHHCCCHHCCCHHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure 
ATGKIVQIIGAVIDVEFPQDAVPKVYDALKVESGLTLEVQQQLGGGLVRCIALGTSDGL
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHCCCEEEEEEECCCHHH
KRGLKVENTGNPIQVPVGTKTLGRIMNVLGEPIDEKGPIGEEARWDIHRAAPSYEEQSNS
HCCCEECCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCHHCCCC
TELLETGIKVIDLICPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGER
HHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCC
TREGNDFYHEMTDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLFFVD
CCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEEEEEECHHHHHHHHHCCCEEEEEEE
NIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADD
CHHHEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCC
LTDPSPATTFAHLDSTVVLSRNIASLGIYPAVDPLDSTSRQLDPLVVGEEHYNVARGVQG
CCCCCCCCCHHHCCCEEEEECCHHHHCCCCCCCCCCCCHHHCCCEEECCCHHHHHHHHHH
TLQRYKELKDIIAILGMDELSEDDKLVVARARKIERFLSQPFFVAEVFTGSPGKYVSLKD
HHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEEHHH
TIRGFKGILEGEFDHIPEQAFYMAGSIDEVVERASKM
HHHHHHHHHCCCHHCCCHHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA