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The map label for this gene is modF [H]

Identifier: 126209050

GI number: 126209050

Start: 1813385

End: 1814857

Strand: Reverse

Name: modF [H]

Synonym: APL_1586

Alternate gene names: 126209050

Gene position: 1814857-1813385 (Counterclockwise)

Preceding gene: 126209051

Following gene: 126209045

Centisome position: 79.79

GC content: 43.58

Gene sequence:

>1473_bases
ATGCCAAATATCAACATCCAGAACGCCTTATTTTCCCTTGCTCAACACAATAAACTGTCGATTGAATCGCTGGAAATCAA
TACTCACGATTTCTGGGTGATTGTCGGCGGTAACGGCTCGGGTAAAACTGCTTTCGCCCAAGCGCTACATAATTCACTTT
CACTATATTCGGGCGAATATCAAAACAGCTTCCAACATATCGCTTTACTTTCCTTCGAGCAGCAACAAAAAATCATCGAG
CAAATCTTTAAACACCGTAACAACGATATGATTTCACCGGATGATTTCGGTTTAACAGCACGTCAAATTATCTTAAACGG
TAGCGAAAAAACGCAATTATGCGAGGAATATGAGGCTAAATTACGCATTCAACCGTTATTAGATCGCCCGTTTATTCAGC
TCTCCACCGGCGAAAGTCGCAAAGTGTTATTTTGCCAAATGTTGGTTAGTGAACCGGATTTATTGATTCTAGATGAGCCT
TTCGAAGGGTTAGACCAAGCCTCGGTCGCTTATTGGCAAGACGTTATGGCGCAACTCGGCAAGCAAATGGCGGTGGTTCT
GATTTCTAACCGCTTTAACGATATTCCCAACTGTGCTACGCATATCGCTTTATTGGATAATCTACAACTGATTTTACAAG
GCGAACGCCAAGCGATTGAGCAACAAGCGGTCTATTCTCAGCTAAAATTTGCAGAACAGAATGTGAATGCGCCGTTACCG
GACAGTGCCGCACCGCTGATTCAGCTCCCACCGAATACCAATCCGTTCGAACTGAAAAACGTGATGATTCGTTACGGCGA
AAAAACCATTATTGATGATCTAACTTGGACGGTTGCCCCAAAACAACATTGGTGGATTAAAGGCCCGAACGGAGCCGGCA
AATCGACCTTACTTTCGATTATTACCGGCGATCATCCGCAGTCTTATGCCAATTCTGTGCATTTATTCGGTCGTCAGCGT
GGCTCCGGCGAAACGATTTGGGATATTAAGAAAAATATCGGCTATGTAAGTAGTCAATTACATATGGATTATCGGGTGAA
TTGTTCGGCGTTAGATGTGATTTTATCCGGCTTTTTTGATTCAATCGGTGTTTACCAACAAGTGCCAAGTGCCTTACAGC
TCAAAGCAATGGAATGGCTGGAACGCTTACATTTAGCCAATCTGGCGAAAAAACCGTTCCGTTCACTTTCGTGGGGGCAA
CAACGTTTATTATTGATTACTCGAGCCATGGTAAAGCATCCGCCGATTCTAATTTTAGACGAACCTCTGCAAGGCTTGGA
TGGTGTAAACCGCAAATTGGTTAAACAGTTTATCGAGCAGTTGGTCACTAACAGCCAAACCCAGTTGCTATTTGTTTCTC
ATCAAGATGCGGACGCCCCAAATTGCATCACCCATTTATTTGAATTTGTCCCGCAAGAGAATGGTGGTTATCGATACGTA
CAGACGGCTTTGAATCAAATAGAAAACGCCTGA

Upstream 100 bases:

>100_bases
AACTCTAACAAATAAAAACTATCGGATACGGAAAACATAACGCACACGCCTAATAATTATTCCATTAGCGTTGTGTTTTC
CGTCATAACAGGAACACAAC

Downstream 100 bases:

>100_bases
GATTTAACCACGGAAAACACAGATTGCACGGAGTTTAATGAATCGGTCAGTTGACGTAATGTTTGGATAATATTGTTTTT
TTCAGGTTTTTCTTATCTCG

Product: putative molybdenum transport ATP-binding protein ModF

Products: NA

Alternate protein names: Photorepair protein PhrA [H]

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MPNINIQNALFSLAQHNKLSIESLEINTHDFWVIVGGNGSGKTAFAQALHNSLSLYSGEYQNSFQHIALLSFEQQQKIIE
QIFKHRNNDMISPDDFGLTARQIILNGSEKTQLCEEYEAKLRIQPLLDRPFIQLSTGESRKVLFCQMLVSEPDLLILDEP
FEGLDQASVAYWQDVMAQLGKQMAVVLISNRFNDIPNCATHIALLDNLQLILQGERQAIEQQAVYSQLKFAEQNVNAPLP
DSAAPLIQLPPNTNPFELKNVMIRYGEKTIIDDLTWTVAPKQHWWIKGPNGAGKSTLLSIITGDHPQSYANSVHLFGRQR
GSGETIWDIKKNIGYVSSQLHMDYRVNCSALDVILSGFFDSIGVYQQVPSALQLKAMEWLERLHLANLAKKPFRSLSWGQ
QRLLLITRAMVKHPPILILDEPLQGLDGVNRKLVKQFIEQLVTNSQTQLLFVSHQDADAPNCITHLFEFVPQENGGYRYV
QTALNQIENA

Sequences:

>Translated_490_residues
MPNINIQNALFSLAQHNKLSIESLEINTHDFWVIVGGNGSGKTAFAQALHNSLSLYSGEYQNSFQHIALLSFEQQQKIIE
QIFKHRNNDMISPDDFGLTARQIILNGSEKTQLCEEYEAKLRIQPLLDRPFIQLSTGESRKVLFCQMLVSEPDLLILDEP
FEGLDQASVAYWQDVMAQLGKQMAVVLISNRFNDIPNCATHIALLDNLQLILQGERQAIEQQAVYSQLKFAEQNVNAPLP
DSAAPLIQLPPNTNPFELKNVMIRYGEKTIIDDLTWTVAPKQHWWIKGPNGAGKSTLLSIITGDHPQSYANSVHLFGRQR
GSGETIWDIKKNIGYVSSQLHMDYRVNCSALDVILSGFFDSIGVYQQVPSALQLKAMEWLERLHLANLAKKPFRSLSWGQ
QRLLLITRAMVKHPPILILDEPLQGLDGVNRKLVKQFIEQLVTNSQTQLLFVSHQDADAPNCITHLFEFVPQENGGYRYV
QTALNQIENA
>Mature_489_residues
PNINIQNALFSLAQHNKLSIESLEINTHDFWVIVGGNGSGKTAFAQALHNSLSLYSGEYQNSFQHIALLSFEQQQKIIEQ
IFKHRNNDMISPDDFGLTARQIILNGSEKTQLCEEYEAKLRIQPLLDRPFIQLSTGESRKVLFCQMLVSEPDLLILDEPF
EGLDQASVAYWQDVMAQLGKQMAVVLISNRFNDIPNCATHIALLDNLQLILQGERQAIEQQAVYSQLKFAEQNVNAPLPD
SAAPLIQLPPNTNPFELKNVMIRYGEKTIIDDLTWTVAPKQHWWIKGPNGAGKSTLLSIITGDHPQSYANSVHLFGRQRG
SGETIWDIKKNIGYVSSQLHMDYRVNCSALDVILSGFFDSIGVYQQVPSALQLKAMEWLERLHLANLAKKPFRSLSWGQQ
RLLLITRAMVKHPPILILDEPLQGLDGVNRKLVKQFIEQLVTNSQTQLLFVSHQDADAPNCITHLFEFVPQENGGYRYVQ
TALNQIENA

Specific function: Involved in the transport of molybdenum into the cell. Involved in photorepair. Could act on UV-induced DNA damage other than pyrimidine dimers [H]

COG id: COG1119

COG function: function code P; ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Escherichia coli, GI1786975, Length=490, Percent_Identity=49.5918367346939, Blast_Score=468, Evalue=1e-133,
Organism=Escherichia coli, GI48994943, Length=371, Percent_Identity=23.4501347708895, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1788165, Length=223, Percent_Identity=27.3542600896861, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI2367384, Length=353, Percent_Identity=23.7960339943343, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1789864, Length=210, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1788761, Length=209, Percent_Identity=28.2296650717703, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789593, Length=216, Percent_Identity=25.462962962963, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787712, Length=209, Percent_Identity=28.2296650717703, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788506, Length=471, Percent_Identity=23.3545647558386, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1789991, Length=448, Percent_Identity=21.2053571428571, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790544, Length=181, Percent_Identity=29.8342541436464, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1786563, Length=213, Percent_Identity=26.7605633802817, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790162, Length=249, Percent_Identity=23.6947791164659, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790525, Length=339, Percent_Identity=21.8289085545723, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1789672, Length=225, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786319, Length=178, Percent_Identity=26.9662921348315, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787370, Length=230, Percent_Identity=26.5217391304348, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787089, Length=208, Percent_Identity=26.4423076923077, Blast_Score=63, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320266, Length=535, Percent_Identity=26.7289719626168, Blast_Score=141, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 55322; Mature: 55191

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNINIQNALFSLAQHNKLSIESLEINTHDFWVIVGGNGSGKTAFAQALHNSLSLYSGEY
CCCCCHHHHHHHHHHCCCCEEEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCHH
QNSFQHIALLSFEQQQKIIEQIFKHRNNDMISPDDFGLTARQIILNGSEKTQLCEEYEAK
HCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHEECCCHHHHHHHHHHHH
LRIQPLLDRPFIQLSTGESRKVLFCQMLVSEPDLLILDEPFEGLDQASVAYWQDVMAQLG
EEEEECCCCCEEEEECCCCCCEEEEEHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHH
KQMAVVLISNRFNDIPNCATHIALLDNLQLILQGERQAIEQQAVYSQLKFAEQNVNAPLP
HHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCC
DSAAPLIQLPPNTNPFELKNVMIRYGEKTIIDDLTWTVAPKQHWWIKGPNGAGKSTLLSI
CCCCCEEECCCCCCCHHHHHHHHHCCCHHHHCCCEEEECCCCCEEEECCCCCCHHHEEEE
ITGDHPQSYANSVHLFGRQRGSGETIWDIKKNIGYVSSQLHMDYRVNCSALDVILSGFFD
HCCCCCHHHHHHEEEEECCCCCCCCHHHHHHHCCHHHHHEECCEECCHHHHHHHHHHHHH
SIGVYQQVPSALQLKAMEWLERLHLANLAKKPFRSLSWGQQRLLLITRAMVKHPPILILD
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEC
EPLQGLDGVNRKLVKQFIEQLVTNSQTQLLFVSHQDADAPNCITHLFEFVPQENGGYRYV
CCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCHHH
QTALNQIENA
HHHHHHHCCC
>Mature Secondary Structure 
PNINIQNALFSLAQHNKLSIESLEINTHDFWVIVGGNGSGKTAFAQALHNSLSLYSGEY
CCCCHHHHHHHHHHCCCCEEEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCHH
QNSFQHIALLSFEQQQKIIEQIFKHRNNDMISPDDFGLTARQIILNGSEKTQLCEEYEAK
HCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHEECCCHHHHHHHHHHHH
LRIQPLLDRPFIQLSTGESRKVLFCQMLVSEPDLLILDEPFEGLDQASVAYWQDVMAQLG
EEEEECCCCCEEEEECCCCCCEEEEEHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHH
KQMAVVLISNRFNDIPNCATHIALLDNLQLILQGERQAIEQQAVYSQLKFAEQNVNAPLP
HHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCC
DSAAPLIQLPPNTNPFELKNVMIRYGEKTIIDDLTWTVAPKQHWWIKGPNGAGKSTLLSI
CCCCCEEECCCCCCCHHHHHHHHHCCCHHHHCCCEEEECCCCCEEEECCCCCCHHHEEEE
ITGDHPQSYANSVHLFGRQRGSGETIWDIKKNIGYVSSQLHMDYRVNCSALDVILSGFFD
HCCCCCHHHHHHEEEEECCCCCCCCHHHHHHHCCHHHHHEECCEECCHHHHHHHHHHHHH
SIGVYQQVPSALQLKAMEWLERLHLANLAKKPFRSLSWGQQRLLLITRAMVKHPPILILD
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEC
EPLQGLDGVNRKLVKQFIEQLVTNSQTQLLFVSHQDADAPNCITHLFEFVPQENGGYRYV
CCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCHHH
QTALNQIENA
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8564363; 8550508; 8905232; 9278503; 8310005 [H]