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The map label for this gene is glmM

Identifier: 126208918

GI number: 126208918

Start: 1667107

End: 1668441

Strand: Reverse

Name: glmM

Synonym: APL_1454

Alternate gene names: 126208918

Gene position: 1668441-1667107 (Counterclockwise)

Preceding gene: 126208919

Following gene: 126208917

Centisome position: 73.35

GC content: 45.92

Gene sequence:

>1335_bases
ATGGCAGAACGTAAATATTTCGGTACGGACGGTGTACGAGGCAAAGTAGGACAATTCCCTATCACTCCGGATTTTGCATT
AAAACTCGGTTGGGCGGCAGGTAAAATTTTGGCAACCCAAGGTACTAAACAAGTGCTAATCGGTAAAGATACGCGTATTT
CAGGTTATATGTTGGAATCGGCATTAGAAGCGGGGCTTGCAGCGGCAGGTCTTTCCGCTGCATTTGTCGGTCCAATGCCG
ACTCCCGCAATCGCATATCTTACGCGTACTTTCCGTGCCGAAGCGGGTATTGTGATTTCCGCATCACATAACCCATATTA
CGATAATGGCATTAAATTCTTCTCAAGTGTCGGGGAAAAATTACCGGACGAAGTGGAAGAAGCAATCGAAGCGTTATTAG
ATCAACCGATGGATTGCGTTGAATCCGCGCAATTAGGTAAAGCCATGCGCATTAATGACGCAGCTGGTCGTTATATCGAA
TTCTGCAAAGGAACATTCCCGGCAAATGCCAGCCTGAAAGGTTATAAAATCGTGGTGGACTGTGCAAACGGCGCAACTTA
CCACATCGCACCGAATGTAATGCGTGAACTTGGTGCGGAAGTGATTGAAATCGGTACCAAGCCGGACGGTTTAAATATCA
ATGAAAAATGCGGCGCAACCGATATTAAAGCGTTACAAAAAGTGGTGGTTGAATCAGGTGCGGACGTTGGTCTTGCTTAT
GACGGTGACGGCGACCGCATTATGATGGTGGATCATTTAGGTAATAAAGTGGACGGCGACCAGATCCTATTTATTATTGC
GCGTGAAGCATTACGTTCGGGCAAATTACACGGTGGTGTAGTCGGTACGTTAATGAGTAATATGGGCTTAGAAGTGGCGT
TGAAACACTTAGCGATTCCATTTACTCGTGCGAATGTCGGCGACCGTTACGTACTCGAACAATTAAAAGAAAAAGGCTGG
AAATTGGGCGGTGAAAACTCAGGTCACATTATCGTGTTAGATAAAAATACGACCGGTGACGGTATTATCGCCTCACTTGA
AGTGTTGGCCGCAATGGAAGCGCATAAAATGAGCTTAAATGACTTAGCGCGCGCCGTACCATTATTCCCACAAGTGTTAA
TTAATGTACGTTTTGAAGGCGGTAAAAATCCGTTAGAAAGCGATGCGGTAAAAGCAGTTGCGGCAGATGTAGAAAAACGT
TTGGCAGGCAAAGGACGTATTCTTTTACGTAAGTCCGGTACCGAGCCGTTAATTCGTGTGATGGTGGAATGCGAAGACGG
TGCGTTGGCACAAAGCTGTGCGGAAGAAATCGTCGAAGCGGTTAAAAGCAACTAA

Upstream 100 bases:

>100_bases
GCCTTGCATATCAATACTTTTTAAAATAAATCGCAGGAATTATTGGTTAAATCGGCTGTCTAATCGGCAGTTTTCACTCT
TCTTTTTTAAGGATCTAACA

Downstream 100 bases:

>100_bases
CTGATGACAAGCGGTCGAATTTTTGCAAAAATTTGCGGAAATTCGACCGCTTTGCTTATCACTAACGACTGATGTTTGTA
CGATAACGAATAAAAGTATC

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MAERKYFGTDGVRGKVGQFPITPDFALKLGWAAGKILATQGTKQVLIGKDTRISGYMLESALEAGLAAAGLSAAFVGPMP
TPAIAYLTRTFRAEAGIVISASHNPYYDNGIKFFSSVGEKLPDEVEEAIEALLDQPMDCVESAQLGKAMRINDAAGRYIE
FCKGTFPANASLKGYKIVVDCANGATYHIAPNVMRELGAEVIEIGTKPDGLNINEKCGATDIKALQKVVVESGADVGLAY
DGDGDRIMMVDHLGNKVDGDQILFIIAREALRSGKLHGGVVGTLMSNMGLEVALKHLAIPFTRANVGDRYVLEQLKEKGW
KLGGENSGHIIVLDKNTTGDGIIASLEVLAAMEAHKMSLNDLARAVPLFPQVLINVRFEGGKNPLESDAVKAVAADVEKR
LAGKGRILLRKSGTEPLIRVMVECEDGALAQSCAEEIVEAVKSN

Sequences:

>Translated_444_residues
MAERKYFGTDGVRGKVGQFPITPDFALKLGWAAGKILATQGTKQVLIGKDTRISGYMLESALEAGLAAAGLSAAFVGPMP
TPAIAYLTRTFRAEAGIVISASHNPYYDNGIKFFSSVGEKLPDEVEEAIEALLDQPMDCVESAQLGKAMRINDAAGRYIE
FCKGTFPANASLKGYKIVVDCANGATYHIAPNVMRELGAEVIEIGTKPDGLNINEKCGATDIKALQKVVVESGADVGLAY
DGDGDRIMMVDHLGNKVDGDQILFIIAREALRSGKLHGGVVGTLMSNMGLEVALKHLAIPFTRANVGDRYVLEQLKEKGW
KLGGENSGHIIVLDKNTTGDGIIASLEVLAAMEAHKMSLNDLARAVPLFPQVLINVRFEGGKNPLESDAVKAVAADVEKR
LAGKGRILLRKSGTEPLIRVMVECEDGALAQSCAEEIVEAVKSN
>Mature_443_residues
AERKYFGTDGVRGKVGQFPITPDFALKLGWAAGKILATQGTKQVLIGKDTRISGYMLESALEAGLAAAGLSAAFVGPMPT
PAIAYLTRTFRAEAGIVISASHNPYYDNGIKFFSSVGEKLPDEVEEAIEALLDQPMDCVESAQLGKAMRINDAAGRYIEF
CKGTFPANASLKGYKIVVDCANGATYHIAPNVMRELGAEVIEIGTKPDGLNINEKCGATDIKALQKVVVESGADVGLAYD
GDGDRIMMVDHLGNKVDGDQILFIIAREALRSGKLHGGVVGTLMSNMGLEVALKHLAIPFTRANVGDRYVLEQLKEKGWK
LGGENSGHIIVLDKNTTGDGIIASLEVLAAMEAHKMSLNDLARAVPLFPQVLINVRFEGGKNPLESDAVKAVAADVEKRL
AGKGRILLRKSGTEPLIRVMVECEDGALAQSCAEEIVEAVKSN

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=444, Percent_Identity=70.4954954954955, Blast_Score=627, Evalue=0.0,
Organism=Escherichia coli, GI1788361, Length=454, Percent_Identity=26.431718061674, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_ACTP2 (A3N2A2)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001054143.1
- ProteinModelPortal:   A3N2A2
- SMR:   A3N2A2
- STRING:   A3N2A2
- GeneID:   4849540
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1454
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- PhylomeDB:   A3N2A2
- ProtClustDB:   PRK10887
- BioCyc:   APLE416269:APL_1454-MONOMER
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 47313; Mature: 47182

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 102-102

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERKYFGTDGVRGKVGQFPITPDFALKLGWAAGKILATQGTKQVLIGKDTRISGYMLES
CCCCCCCCCCCCCCCCCCCCCCCCHHEEECCCCCEEEECCCCCEEEEECCCCCHHHHHHH
ALEAGLAAAGLSAAFVGPMPTPAIAYLTRTFRAEAGIVISASHNPYYDNGIKFFSSVGEK
HHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHC
LPDEVEEAIEALLDQPMDCVESAQLGKAMRINDAAGRYIEFCKGTFPANASLKGYKIVVD
CHHHHHHHHHHHHCCCHHHHHHHHCCCEEEECHHHHHHHHHHCCCCCCCCCCCCEEEEEE
CANGATYHIAPNVMRELGAEVIEIGTKPDGLNINEKCGATDIKALQKVVVESGADVGLAY
CCCCCEEEECHHHHHHHCHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEE
DGDGDRIMMVDHLGNKVDGDQILFIIAREALRSGKLHGGVVGTLMSNMGLEVALKHLAIP
CCCCCEEEEEECCCCCCCCCCEEEEEEHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHCC
FTRANVGDRYVLEQLKEKGWKLGGENSGHIIVLDKNTTGDGIIASLEVLAAMEAHKMSLN
CCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHH
DLARAVPLFPQVLINVRFEGGKNPLESDAVKAVAADVEKRLAGKGRILLRKSGTEPLIRV
HHHHHHHHCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEE
MVECEDGALAQSCAEEIVEAVKSN
EEECCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AERKYFGTDGVRGKVGQFPITPDFALKLGWAAGKILATQGTKQVLIGKDTRISGYMLES
CCCCCCCCCCCCCCCCCCCCCCCHHEEECCCCCEEEECCCCCEEEEECCCCCHHHHHHH
ALEAGLAAAGLSAAFVGPMPTPAIAYLTRTFRAEAGIVISASHNPYYDNGIKFFSSVGEK
HHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHC
LPDEVEEAIEALLDQPMDCVESAQLGKAMRINDAAGRYIEFCKGTFPANASLKGYKIVVD
CHHHHHHHHHHHHCCCHHHHHHHHCCCEEEECHHHHHHHHHHCCCCCCCCCCCCEEEEEE
CANGATYHIAPNVMRELGAEVIEIGTKPDGLNINEKCGATDIKALQKVVVESGADVGLAY
CCCCCEEEECHHHHHHHCHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEE
DGDGDRIMMVDHLGNKVDGDQILFIIAREALRSGKLHGGVVGTLMSNMGLEVALKHLAIP
CCCCCEEEEEECCCCCCCCCCEEEEEEHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHCC
FTRANVGDRYVLEQLKEKGWKLGGENSGHIIVLDKNTTGDGIIASLEVLAAMEAHKMSLN
CCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHH
DLARAVPLFPQVLINVRFEGGKNPLESDAVKAVAADVEKRLAGKGRILLRKSGTEPLIRV
HHHHHHHHCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEE
MVECEDGALAQSCAEEIVEAVKSN
EEECCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA