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The map label for this gene is rpiA

Identifier: 126208917

GI number: 126208917

Start: 1666301

End: 1666960

Strand: Reverse

Name: rpiA

Synonym: APL_1453

Alternate gene names: 126208917

Gene position: 1666960-1666301 (Counterclockwise)

Preceding gene: 126208918

Following gene: 126208916

Centisome position: 73.29

GC content: 47.27

Gene sequence:

>660_bases
ATGACCCAACAAGAAATGAAAAAAATTGCCGCTCAAGCTGCGCTTCAATTCGTCAAACCGGATACCATCGTGGGGGTGGG
TAGCGGTTCTACCGTAAACTGTTTTATCGATGCGTTAGCCTCTATGAAAGATCAAATTAAAGGTGCGGTTGCCGCCTCCA
AAGCGTCCGAAGAACGTTTACGTGCGATCGGCATCGAAGTATTCAATGCAAATGAAGTCAGCGAATTGGACGTTTATATC
GACGGTGCGGATGAAATTACCCCTCAAGGCGCAATGATTAAAGGCGGCGGTGCGGCATTAACCCGAGAAAAAATCGTTAG
CTCGCTGGCGAAAAAATTCGTTTGTATCGTGGACGGTTCAAAACAAGTGGACGTATTAGGCACAACCTTCCCGTTACCGG
TCGAAGTGATCCCGATGGCACGTTCGTATGTCGCCCGTCAATTAGTGGCATTAGGCGGTTCGCCGGAATACCGTGAAGGC
GTGGTCACCGATAACGGTAATGTAATTTTAGACGTGCATAATTTCCACATTATCGAACCGCTTAAAATGGAACATACCAT
CAATAACATCGCCGGTGTGGTTACCAACGGTATCTTTGCGCAACGCTATGCGAACGTAACCATTGTCGGTACGCCGGAAG
GTGCGAAAATTATTGAATAA

Upstream 100 bases:

>100_bases
CCGCTTTGCTTATCACTAACGACTGATGTTTGTACGATAACGAATAAAAGTATCGTGTTTACCTATATCTTAAAATAATA
CTAATTAAAAAGGATGGATT

Downstream 100 bases:

>100_bases
ATTCGCTATTCACCATCTTAAAACACACGAAAATTTTTCTTGATTTGTTATGACGATAACTTCTATCAAATTCAAAAATT
TTTCGTGTGTTTATCTTTAT

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MTQQEMKKIAAQAALQFVKPDTIVGVGSGSTVNCFIDALASMKDQIKGAVAASKASEERLRAIGIEVFNANEVSELDVYI
DGADEITPQGAMIKGGGAALTREKIVSSLAKKFVCIVDGSKQVDVLGTTFPLPVEVIPMARSYVARQLVALGGSPEYREG
VVTDNGNVILDVHNFHIIEPLKMEHTINNIAGVVTNGIFAQRYANVTIVGTPEGAKIIE

Sequences:

>Translated_219_residues
MTQQEMKKIAAQAALQFVKPDTIVGVGSGSTVNCFIDALASMKDQIKGAVAASKASEERLRAIGIEVFNANEVSELDVYI
DGADEITPQGAMIKGGGAALTREKIVSSLAKKFVCIVDGSKQVDVLGTTFPLPVEVIPMARSYVARQLVALGGSPEYREG
VVTDNGNVILDVHNFHIIEPLKMEHTINNIAGVVTNGIFAQRYANVTIVGTPEGAKIIE
>Mature_218_residues
TQQEMKKIAAQAALQFVKPDTIVGVGSGSTVNCFIDALASMKDQIKGAVAASKASEERLRAIGIEVFNANEVSELDVYID
GADEITPQGAMIKGGGAALTREKIVSSLAKKFVCIVDGSKQVDVLGTTFPLPVEVIPMARSYVARQLVALGGSPEYREGV
VTDNGNVILDVHNFHIIEPLKMEHTINNIAGVVTNGIFAQRYANVTIVGTPEGAKIIE

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=212, Percent_Identity=34.4339622641509, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1789280, Length=218, Percent_Identity=66.0550458715596, Blast_Score=294, Evalue=3e-81,
Organism=Caenorhabditis elegans, GI17551758, Length=214, Percent_Identity=36.4485981308411, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6324669, Length=237, Percent_Identity=29.957805907173, Blast_Score=79, Evalue=6e-16,
Organism=Drosophila melanogaster, GI281364072, Length=203, Percent_Identity=33.0049261083744, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_ACTP2 (A3N2A1)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001054142.1
- ProteinModelPortal:   A3N2A1
- SMR:   A3N2A1
- STRING:   A3N2A1
- GeneID:   4850152
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1453
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   VFDLNSV
- PhylomeDB:   A3N2A1
- ProtClustDB:   PRK00702
- BioCyc:   APLE416269:APL_1453-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 23255; Mature: 23124

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQEMKKIAAQAALQFVKPDTIVGVGSGSTVNCFIDALASMKDQIKGAVAASKASEERL
CCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAIGIEVFNANEVSELDVYIDGADEITPQGAMIKGGGAALTREKIVSSLAKKFVCIVDGS
HHHEEEEECCCCCEEEEEEECCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHEEEEECCC
KQVDVLGTTFPLPVEVIPMARSYVARQLVALGGSPEYREGVVTDNGNVILDVHNFHIIEP
CEEEEEECCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEECCEEEECC
LKMEHTINNIAGVVTNGIFAQRYANVTIVGTPEGAKIIE
HHHHHHHHHHHHHHHCCHHHHHHCCEEEEECCCCCCCCC
>Mature Secondary Structure 
TQQEMKKIAAQAALQFVKPDTIVGVGSGSTVNCFIDALASMKDQIKGAVAASKASEERL
CHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAIGIEVFNANEVSELDVYIDGADEITPQGAMIKGGGAALTREKIVSSLAKKFVCIVDGS
HHHEEEEECCCCCEEEEEEECCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHEEEEECCC
KQVDVLGTTFPLPVEVIPMARSYVARQLVALGGSPEYREGVVTDNGNVILDVHNFHIIEP
CEEEEEECCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEECCEEEECC
LKMEHTINNIAGVVTNGIFAQRYANVTIVGTPEGAKIIE
HHHHHHHHHHHHHHHCCHHHHHHCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA